Global space startup and innovation connector opens Houston branch

Space city win

Australia-based Moonshot has opened a Houston chapter. Miriam Espacio / Pexels

It's almost an understatement to say that Houston's space economy is taking off like a rocket.

On May 28, four companies in the Houston area — Axiom Space Inc., Boeing Co., KBRwyle, and NanoRacks LLC — were tasked with helping chart NASA's course in the space economy, whose global value is projected to climb as high as $3 trillion by 2040. Three days later, Houston-based Intuitive Machines LLC was awarded a $77.2 million contract to send as many as five NASA payloads to the moon.

And a month later, on June 26, officials broke ground on the first phase of Houston Spaceport, a 450-acre project at Ellington Airport that will serve as a sort of control center for aerospace research and manufacturing, and commercial space operations.

Then, on July 19 — a day ahead of the 50th anniversary of Apollo 11 man-on-the-moon mission — Australia-based startup Moonshot Space Co. launched a chapter in Houston to help foster the region's multibillion-dollar space economy. Through its programming, which will kick off this fall, Moonshot seeks to corral entrepreneurs, students, job seekers, business executives, investors, university researchers, government officials, and others in an effort to nurture and promote Houston's space economy.

Troy McCann, founder and CEO of Moonshot, believes Houston — home to NASA's Johnson Space Center — can emerge as the epicenter of the global space economy.

"You'd have to have been living under a rock for the past 50 years not to be aware of Houston's stellar aerospace ecosystem," McCann says. "It's got both the historical credibility and a suite of … successful commercial space ventures based there."

"We want to help fine-tune Houston's space economy by providing a proven framework to elevate people and their ideas into successful teams and scalable businesses," McCann adds, "and to create the industries of the future and solve humanity's greatest challenges."

The Houston chapter, a nonprofit venture, is Moonshot's first in the U.S. and second outside Australia. Nathan Johnson, a Houston attorney who specializes in space law and business development, has been tapped to direct it.

"We're in the process of starting chapters across the globe because we believe that the next Nikola Tesla or Marie Curie is out there somewhere, but they don't have access to the resources they need to change the world for the better," McCann says. "Today, the average person has the ability to start a commercial space program for less than the cost of a fast-food franchise."

Johnson says Houston's prominence as NASA's hub for human spaceflight, its status as the "Energy Capital of the World," and the presence of the Texas Medical Center combine to make Space City a potent force in the space economy.

"My hope is to see Houston continue to lead in space and become a hub for the next wave of space commercialization," Johnson says. "We have a wide breadth of industries, and I would like to see that terrestrial expertise extend to new market applications in space."

If Houston does evolve into a nucleus for the global space economy, it stands to reap sky-high financial rewards. Various analysts forecast the global space economy will soar to between $1 trillion and $3 trillion by 2040, up from an estimated $415 billion in 2018.

"Space is and will be a global endeavor, depending on a strong economy, smart industries, and a talented workforce," Johnson says. "Houston already has all of those things, continues to actively develop them at all levels of the community, and does so in a way that reflects the world's population."

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UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.

New Texas Stock Exchange officially begins trading in Dallas

Welcome to Y'all Street

Two-step aside, New York Stock Exchange and Nasdaq. The Dallas-based Texas Stock Exchange, nicknamed Y’all Street, just kicked off live trading with five stocks — and lots of Lone Star ambition.

“The Texas Stock Exchange aims to revitalize competition for [stock] issuers, establish the premier venue for listings, and create a world-class trading platform for all market participants,” the exchange says in a fact sheet.

The exchange — whose Texas-influenced nickname is a nod to New York City’s Wall Street — has collected at least $275 million in investments. The roughly 90 financial backers of TXSE include Bank of America, BlackRock, Charles Schwab, Citadel Securities, Dell Family Office, Fortress, Goldman Sachs, and JPMorgan Chase.

Representatives of TXSE couldn’t be reached for comment. On its website, the exchange calls itself “the most well-capitalized equities exchange to ever be approved” by the U.S. Securities and Exchange Commission (SEC).

Not to be outdone, NYSE has launched Dallas-based NYSE Texas and Nasdaq has expanded its presence in Dallas.

Y’all Street adds to Dallas-Fort Worth’s rising status as a major hub for financial services, with The Wall Street Journal naming North Texas the country’s second biggest financial hub after New York City.

“A homegrown national exchange means more jobs, more investment, and more growth opportunities for businesses and communities across the Lone Star State,” Gabriela von zur Muehlen, senior vice president and chief policy officer at the Texas Association of Business, told The Texas Tribune.

Bulent Temel, an associate professor of practice in economics at the University of Texas at San Antonio, told Texas Standard that TXSE “is going to boost the credibility of the Texas economy.”

Texas’ estimated gross domestic product (GDP), a yardstick for the size of an economy, climbed to a record-setting $2.9 trillion in 2025, making it the state with the second highest GDP after California. DFW’s estimated GDP in 2023 stood at $744.6 billion, eclipsing the GDP of many countries.

“The center of gravity for American capitalism is now headquartered in the Boom Belt,” Abbott proclaimed in April, referring to an 11-state region (including Texas) in the South and Southeast that’s seeing tremendous economic and population growth. “The Texas Stock Exchange is the natural extension of that capitalism. It ensures that capital markets will reflect the quadrant that is driving American growth.”

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This article originally appeared on CultureMap.com.

Orion vehicle manager reflects on Artemis II, looks to 2028 moon mission

Q&A

Humanity is finally headed back to the moon after more than half a century. This year's launch of the Artemis II mission in the Orion spacecraft put four crew members in lunar orbit and tested the new ship developed by Lockheed Martin.

Everything went smoothly, safely returning astronauts home, but there is always room to improve. InnovationMap chatted via email with Orion vehicle manager Branelle Rodriguez, shortly after a talk at The Ion, for insight on how Orion might perform in the future as the next lunar landing approaches in early 2028.

InnovationMap: How satisfied are you with the way Orion operated on this past mission?

Branelle Rodriguez: Orion performed exceptionally well during Artemis II, successfully demonstrating critical spacecraft capabilities, including life support systems, displays and controls, and executing manual piloting operations. Artemis II brought humans back to the moon, achieving key exploration and scientific imagery, while validating systems essential for future Artemis missions.

IM: What is the most important thing you learned about improving Orion for the next mission?

BR: The Artemis II mission provided invaluable insights into crew operations and spacecraft performance in a deep-space environment. With every mission, NASA applies lessons learned to continuously improve Orion’s operations, validate design and ensure mission readiness. Artemis II offered our first opportunity to evaluate several new systems and gain a deeper understanding of what it is like for astronauts to live and work inside the spacecraft. The operational, technical and human factors data collected are being integrated across the program to refine future missions, reduce risk and enhance overall mission success.

IM: How has Orion helped the mission to explore space?

BR: Orion is one of NASA’s foundational elements for human deep space exploration—not only supporting the mission but serving as a core component of it. It is currently the only spacecraft capable of carrying crew on deep space missions and returning them safely to Earth from the high speeds required from the vicinity of the moon. No other spacecraft has the technology to endure the extremes that come with human deep-space travel, such as advanced environmental and life support, navigation, communications, radiation shielding, and the world’s largest ablative heat shield to protect the astronauts during reentry into Earth’s atmosphere. Orion has already taken astronauts to explore space farther than ever before—252,756 miles from Earth— and will carry crews to the moon on future missions to explore the lunar South Pole region. The astronauts’ observations, samples, and data collected on these future missions will expand our understanding of our solar system and home planet.

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This conversation has been edited for brevity and clarity.

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