Two Houston entrepreneurs — Molly Voorhees (left) and Christina Milligan — have launched a new line of sanitizing products. Photo via instagram.com/cobaltclean

Houstonians Molly Voorhees and Christina Milligan have officially launched a line of hand sanitizing and surface cleaning products that blend the importance of cleanliness and safety with the added value of accessibility and a refined appearance.

The products make up the entrepreneurs' new brand, Cobalt, that Voorhees, president of Beck's Prime, and Milligan, an organizing and style expert, first conceptualized in March. As working parents of young children, the two women wanted to create a line of sanitizing products that boosted their confidence in the safety of their environments amid a pandemic and that they'd be proud to pull out of their purse on short notice.

"Cleaning products are in your bathroom or are in an ugly looking bottle or the back of our restaurant in massive chemical containers. There is really nothing for the on-the-go market," Voorhees says.

Too, the women didn't want to stop at hand sanitizer. Instead, they sought to encourage and educate clientele on the importance of cleaning high-touch surfaces, like phones, steering wheels, sunglasses, and the likes.

"It really resonated with us that your hands are only as clean as the surfaces that you touch," Milligan says. "We wanted it to be very approachable and easy to understand and also discrete. We didn't want anyone to feel ashamed if they pulled out a bottle of Lysol on a table."

The result was six FDA-approved sanitizers, sprays, keychains, and to-go kits that eliminate 99.9 percent of bacteria and viruses in easy to access, personal-sized, contemporary bottles, ranging from $14 to $30. The products are designed to be free of harsh, alcoholic odors and come in scents like peppermint and bubble gum.


The duo business women wanted to avoid harsh alcoholic smells and opted for calming and fun scents. Photo courtesy of Cobalt

Each item in the line boasts sleek, trendy designs in a cool blue hue. And while they look quite polished today, bringing the line to launch started off as a somewhat messy process.

"We kinda thought it would be easy. We would just put cleaner in a 4-ounce bottle and that would be fine," Milligan says.

But due to the high demand for chemical products in the pandemic and the way that industrial filling lines are set up, producing cleaning products in personal-sized bottles proved difficult. The women, who became known as the "the girls who want to put cleaner in their purse," were initially met with a resounding "no" from large chemical corporations.

However, by the summer the duo was able to make more headway. They were nearing production with a chemical partner when they learned of a local business who could produce their product by hand all within the Bayou City.

"It turned out through a connection we were making with labels that we discovered [William Price Distilling Company] that was right in our backyard in Houston that was newly filling bottles," Milligan says. "They were employing out of work restaurant staff. Molly and I both felt really strongly about that."

Voorhees and Milligan quickly partnered up with the Garden Oaks-Oak Forest distillery and have since produced roughly 2,500 units of their various products.

In fact, the line is decidedly Houston-based. In addition to William Price, Cobalt was also created with the help of Houston Labels for design. Deutser helped the team from a business management perspective. And the custom scents were developed by Clarity Fragrance near Memorial City.

As of press time, the products are available for purchase online and in area boutiques, including Emerson Sloan, Lexington Boutique, Zadok Jewelers, Therapy Hair Studio, and The Chocolate Bar. They aim to expand to more stores and markets and adapt the line based on demand.

"We feel so fortunate that we have a variety of products," Voorhees says. "It's always my belief that the consumer will tell you what they want and you go in that direction."

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Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”