Sani nudge has developed a hand hygiene tool that prompts medical professionals to clean their hands more often. Courtesy of TMC

Sani nudge, a graduate of the TMCx healthcare accelerator's nineth cohort at Houston's Texas Medical Center, is getting a significant nudge from a new collaboration with a social-impact organization based in California.

Among more than 1,000 startups that were considered, Copenhagen, Denmark-based Sani nudge was chosen as one of nine participants in the Mistletoe Research Fellowship Startup Collaboration Program, sponsored by the Mistletoe Foundation. Three dozen researchers from seven universities also are taking part in the program.

Fresh off a $1.2 million funding round, Sani nudge's technology is an automated monitoring system aimed at helping healthcare workers bolster hygiene compliance and processes through insights from data and a feature that "nudges" healthcare workers to practice proper hand hygiene. Sani nudge created the technology in conjunction with Bispebjerg Hospital and Aarhus University Hospital, both in Denmark.

In the Mistletoe program, representatives of Sani nudge will work alongside four American researchers to improve the startup's technology, thereby providing hospitals with better data and tapping the researchers' expertise in engineering and robotics to come up with related healthcare platforms. Sani nudge employs 13 people in the U.S., Denmark, and Poland.

During tests in healthcare settings, the use of Sani nudge has resulted in a jump in hand hygiene compliance of as much as 200 percent and a reduction in infections of at least 29 percent, the company says. Several hospitals in Scandinavia are using the Sani nudge system.

Theis Jensen, CEO of Sani nudge, and Dr. Marco Bo Hansen, the chief customer officer, became acquainted with Mistletoe when they met Mark Castleman — a partner at the Mistletoe Inc. global-impact investment fund — during a startup and innovation tour of Texas organized by Capital Factory, a startup accelerator with locations in Houston, Austin, and Dallas.

The three men soon found common ground in a shared vision for reducing hospital-acquired infections and combating resistance to antibiotics. Both are costly, potentially fatal problems.

At any given time, 1 in 25 patients in the U.S. are fighting hospital-acquired infections, the U.S. Department of Health and Human Services says. "These infections lead to the loss of tens of thousands of lives," according to the department, "and cost the U.S. healthcare system billions of dollars each year."

Meanwhile, more than 2 million people in the U.S. are infected each year with antibiotic-resistant bacteria, and at least 23,000 people die as a result, according to the U.S. Centers for Disease Control and Prevention (CDC).

Sani nudge's participation in the Mistletoe program kicked off July 31 and August 1 at a workshop in Tokyo. For the next nine months, the Sani nudge group — led by Rebekah Alexander, the startup's in-house data expert — will team up with its four assigned researchers to advance the startup's wireless technology.

The researchers "will work with us over the following academic year to help us take the Sani nudge solution to the next level and enable hospitals to get even more detailed hand hygiene information that can eliminate hospital-acquired infections," Sani nudge wrote on its blog.

In June 2020, the next-level Sani nudge technology is scheduled to be presented to potential investors and academic researchers in Silicon Valley. Sani nudge says Mistletoe effort will strengthen its ties to the U.S. market and the academic research community.

"There are many opportunities within healthcare IoT that can help both patients and hospitals, and our system is designed to embrace these opportunities," Hansen says.

Hansen, a physician, says he'll be vigilantly advocating that his Sani nudge colleagues and the Mistletoe researchers keep hospital patients and staff in mind as Sani nudge moves forward with its innovations.

"We have to make sure that our solutions always generate value to the end users and can easily be used by the clinicians, infection preventionists, and hospital managers," he says.

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Houston space tech companies land $25 million from Texas commission

Out Of This World

Two Houston aerospace companies have collectively received $25 million in grants from the Texas Space Commission.

Starlab Space picked up a $15 million grant, and Intuitive Machines gained a $10 million grant, according to a Space Commission news release.

Starlab Space says the money will help it develop the Systems Integration Lab in Webster, which will feature two components — the main lab and a software verification facility. The integration lab will aid creation of Starlab’s commercial space station.

“To ensure the success of our future space missions, we are starting with state-of-the-art testing facilities that will include the closest approximation to the flight environment as possible and allow us to verify requirements and validate the design of the Starlab space station,” Starlab CEO Tim Kopra said in a news release.

Starlab’s grant comes on top of a $217.5 million award from NASA to help eventually transition activity from the soon-to-be-retired International Space Station to new commercial destinations.

Intuitive Machines is a space exploration, infrastructure and services company. Among its projects are a lunar lander designed to land on the moon and a lunar rover designed for astronauts to travel on the moon’s surface.

The grants come from the Space Commission’s Space Exploration and Aeronautics Research Fund, which recently awarded $47.7 million to Texas companies.

Other recipients were:

  • Cedar Park-based Firefly Aerospace, which received $8.2 million
  • Brownsville-based Space Exploration Technologies (SpaceX), which received $7.5 million
  • Van Horn-based Blue Origin, which received $7 million

Gwen Griffin, chair of the commission, says the grants “will support Texas companies as we grow commercial, military, and civil aerospace activity across the state.”

State lawmakers established the commission in 2023, along with the Texas Aerospace Research & Space Economy Consortium, to bolster the state’s space industry.

Houston experts: Can AI bridge the gap between tech ambitions and market realities?

guest column

Despite successful IPOs from the likes of Ibotta, Reddit and OneStream, 2024 hasn’t provided the influx of capital-raising opportunities that many late-stage tech startups and venture capitalists (VCs) have been waiting for. Since highs last seen in 2021—when 90 tech companies went public—the IPO market has been effectively frozen, with just five tech IPOs between January and September 2024.

As a result, limited partners have not been able to replenish investments and redeploy capital. This shifting investment landscape has VCs and tech leaders feeling stuck in a holding pattern. Tech leaders are hesitant to enter the public markets because valuations are down 30 percent to 40 percent from 2021, which is also making late-stage fundraising more challenging. After all, longer IPO timelines mean fewer exit opportunities for VCs and reduced capital from institutional investors who are turning toward shorter-term investments with more liquid exit options.

Of course, there’s always an exception. And in the case of a slowed IPO market, a select slice of tech companies—AI-related companies—are far outperforming others. While not every tech startup has AI software or infrastructure as their core offering, most can benefit from using AI to revise their playbook and become more attractive to investors.

Unlocking Growth Potential with AI

While overall tech startup investment has slowed, the AI sector burns bright. This presents an opportunity for companies that strategically leverage AI, not just as a buzzword but as a tool for genuine growth and differentiation. Imagine a future where AI-powered insights unlock unprecedented efficiency, customer engagement and a paradigm shift in value creation. This isn’t just about weathering the current storm of reduced access to capital; it’s about emerging stronger, ready to lead the next wave of tech innovation.

Here's how to navigate the AI frontier and unlock its potential:

  1. Understand that data is the foundation of AI success. AI is powerful, but it’s not magic. It thrives on high-quality, interconnected data. Before diving into AI initiatives, companies must assess their data health. Is it structured in a way that AI can understand? Does it go beyond raw numbers to capture context and meaning—like customer sentiment alongside sales figures? Rethinking data infrastructure is often the crucial first step.
  1. Focus on amplifying strengths, not reinventing the wheel. The allure of AI can tempt companies into pursuing radical reinvention. However, a more effective strategy is to leverage AI to enhance existing strengths and address core customer needs. Why do customers choose your company? How can AI supercharge your value proposition? Consider Reddit’s strategic approach: They didn’t overhaul their platform before their 2024 IPO. Instead, they showcased the value of their vast online communities as fertile ground for AI development, leading to a remarkable first-day stock surge of 48 percent.

  2. Use AI as a customer-centric force multiplier. Companies with a deep understanding of their customer base are primed for AI success. By integrating AI into the very core of their product or service—the reason customers choose them—they can create a decisive competitive advantage based on delivering tangible customer value.

From Incremental Gains to Transformative Growth

This practical, customer-centric approach has the potential to help companies generate immediate growth while laying the foundation for future reinvention. By leveraging AI to optimize operations, deepen customer relationships, and redefine industry paradigms, late-state tech startups can not only survive but thrive in a dynamic market. The future belongs to those who embrace AI not as a destination but as a continuous journey of innovation and growth.

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Hong Ogle is the president of Bank of America Houston. Rodrigo Ortiz Gomez is a market executive in Bank of America’s Transformative Technology Banking Group as well as the national software banking lead for the Global Commercial Bank.

Houston joint venture secures $5.2M for AI-powered methane tracking tech

Fresh Funds

Houston-based Envana Software Solutions has received more than $5.2 million in federal and non-federal funding to support the development of technology for the oil and gas sector to monitor and reduce methane emissions.

Thanks to the work backed by the new funding, Envana says its suite of emissions management software will become the industry's first technology to allow an oil and gas company to obtain a full inventory of greenhouse gases.

The funding comes from a more than $4.2 million grant from the U.S. Department of Energy (DOE) and more than $1 million in non-federal funding.

“Methane is many times more potent than carbon dioxide and is responsible for approximately one-third of the warming from greenhouse gases occurring today,” Brad Crabtree, assistant secretary at DOE, said in 2024.

With the funding, Envana will expand artificial intelligence (AI) and physics-based models to help detect and track methane emissions at oil and gas facilities.

“We’re excited to strengthen our position as a leader in emissions and carbon management by integrating critical scientific and operational capabilities. These advancements will empower operators to achieve their methane mitigation targets, fulfill their sustainability objectives, and uphold their ESG commitments with greater efficiency and impact,” says Nagaraj Srinivasan, co-lead director of Envana.

In conjunction with this newly funded project, Envana will team up with universities and industry associations in Texas to:

  • Advance work on the mitigation of methane emissions
  • Set up internship programs
  • Boost workforce development
  • Promote environmental causes

Envana, a software-as-a-service (SaaS) startup, provides emissions management technology to forecast, track, measure and report industrial data for greenhouse gas emissions.

Founded in 2023, Envana is a joint venture between Houston-based Halliburton, a provider of products and services for the energy industry, and New York City-based Siguler Guff, a private equity firm. Siguler Gulf maintains an office in Houston.

“Envana provides breakthrough SaaS emissions management solutions and is the latest example of how innovation adds to sustainability in the oil and gas industry,” Rami Yassine, a senior vice president at Halliburton, said when the joint venture was announced.

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This story originally appeared on our sister site, EnergyCapitalHTX.com