Houston early stage startup accelerator introduces latest cohort

growing gains

The latest cohort from gBETA Houston has been announced and is currently underway at the Downtown Launchpad. Photo courtesy of Downtown Launchpad

Five Houston startups are joining a global accelerator for a seven-week program to strategically grow their businesses.

Houston's gBETA, a part of gener8tor in partnership with the Downtown Launchpad, has launched its spring cohort — the seventh cohort since its launch in Houston in 2019 — this month. The free program lasts seven weeks and connects companies to gener8tor's network of mentors, customers, corporate partners, and investors.

“We’re thrilled to partner with Downtown Launchpad to bring these programs to life and bolster the technology and sustainability industries in Houston,” says Lauren Usher, gener8tor gBETA vice president, in a news release.

gBETA's equity-free model provides coaching for its cohort companies, which are all Houston-based, home-grown.

“It’s exciting to see the seventh cohort of gBETA Houston come together. We’ve seen so much growth from our previous alumni from our program, and we’re excited for that same impact to flourish with this incoming cohort,” says Muriel Foster, gBETA Houston director, in the release.

The ongoing cohort's members include:

  • Adaptagym revolutionizes the fitness and rehabilitation industries by offering a comprehensive and user-friendly platform that caters to the unique needs of all persons on the ability spectrum. The company matches users with the appropriate fitness and allied health professionals. Adaptagym is currently partnering with one clinic and four individuals for beta testing.
  • Circle.ooo is a B2B2C technology company streamlining event tech for small-to-medium event hosts, attendees and sponsors. The app-within-app concept allows event holders to create a free ‘Circle’, and Attendees create a single 'universal profile' digicard to instantly register for any Event without having multiple accounts, profiles or inputting data fields. Circle is a Houston-based Delaware C-Corp, is currently testing v 2.0 of the app, and has 27 customers on their waitlist.
  • Financial Aid Frenzy transforms the way students pay for college, one dollar at a time. Financial Aid Frenzy's crowdfunding platform is tailored to assist students in getting the money needed for their education by connecting them with donors who are passionate about helping them achieve their educational fundraising goals. Financial Aid Frenzy is a Houston-based Delaware C-Corp, with 40 customers interested in the platform.
  • Kash-In Academy utilizes digital “kash” to increase student engagement through monetized lessons and quizzes. With the Kash-In Academy platform, teachers are able to deposit “kash” for positive behavior and academic achievement. Kash-In Academy is approved in 12 school districts servicing 932 teachers and 8,069 students.
  • MendIt’s apparel care marketplace amplifies the choices for consumers to manage their closets more sustainably and empowers retailers with aftercare solutions that elevate their brand. Retailers work with MendIt to offer long-term product care to customers, helping to extend the life of their clothing, save money through reduced returns, and direct capital to local businesses. MendIt’s product is live and available nationwide via shipping, with three local drop-off locations in the Houston market, a waiting list of “menders” across 9 states, and hundreds of garments mended to date.
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This week's roundup of Houston innovators includes Kaitlyn Allen of MendIt, Miguel Calatayud of iwi, and Tatiana Fofanova of Koda Health. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from sustainability to health tech — recently making headlines in Houston innovation.

Kaitlyn Allen, founder and chief strategy officer of MendIt

MendIt seeks to reduce textile waste by providing an easy-to-use app to make menders and customizers more accessible. Photo courtesy of MendIt

Kaitlyn Allen thought she had a great idea for a company — something that can help people repair clothing conveniently. And all of the pieces of the strategy already existed. There are plenty of seamstressing businesses around town, but not an easy way to navigate them. “

There’s a disconnect. There’s a market of people who potentially want to mend their clothes, but there’s no easy way of finding or accessing that service,” she says. “With this next generation, you need to meet them where they are.”

And where they are, Allen says, is on their phones.

MendIt is completing a pilot program with one mender — Connect Community in Gulfton area — in partnership with St. Luke's Gethsemane on Bellaire in Sharpstown. She also hopes to tap into a local artist who can help with customization — like embroidery, for instance. Click here to read more.

Miguel Calatayud, CEO of iwi

Miguel Calatayud, CEO of iwi, joins the Houston Innovators Podcast to discuss his sustainable business of farming algae for nutritional products. Photo courtesy of iwi

Miguel Calatayud feels like he has the perfect storm of a product. Not only does his company iwi's nutritional supplement have a sustainability focus, it's also just a very competitive product in the marketplace. The company has created a sustainable suite of products from innovative algae farming in the deserts of Texas and New Mexico. These football field-sized farms operate on desert land using just salt water and sand and produce algae sustainably — all while absorbing CO2.

"We've been growing significantly for one main reason," Calatayud says. "It works."

Calatayud shares more about the impact he's making and why Houston is the ideal market for him to do it in on the Houston Innovators podcast. Click here to read more.

Tatiana Fofanova, co-founder and CEO of Koda Health

Tatiana Fofanova, co-founder and CEO of Koda, closed recent funding for the digital health startup. Image via LinkedIn

Tatiana Fofanova, Koda co-founder and CEO, has something to celebrate. The Houston-based startup announced this month that it raised $3.5 million in its latest seed round. The funding will be used to help the digital advanced care planning company double the size of its team in the next six months.

"Koda Health helps vulnerable people navigate and communicate difficult decisions about their health care journey. So, when hiring, we look for empathetic people who are phenomenal communicators," Tatiana Fofanova, Koda co-founder and CEO, says in a statement.

The Koda team will also use the funds to expand its operations to all 50 states. According to the statement, the team plans to focus on low-resource communities and operating in different languages. Click here to read more.

MendIt seeks to reduce textile waste by providing an easy-to-use app to make menders and customizers more accessible. Photo courtesy of MendIt

Houston startup tackles fast fashion with app that connects users to small business menders

sustainable startup

When Kaitlyn Allen’s grandmother died, she left a green sweater that Allen wanted to keep and wear in memory of her. But the sweater had a hole in it and, in a morbidly ironic fashion, the person Allen would have turned to to mend the sweater was her grandmother.

This sparked an idea for the Houstonian, who thought there might be other people out there with the same mending needs.

“We have two generations of people who don’t know how to sew,” Allen tells InnovationMap. “We did national studies to see where people fall within this, and only 4.2 percent of Americans actually take their clothes to get repaired.”

The rest of people, as one might assume, are just buying new clothes and throwing old items out, contributing to a massive — and growing — carbon footprint. Allen — who’s spent almost a decade running Global Affairs Associates, a sustainability consultancy — decided to look into just how big an impact the textile industry had.

Kaitlyn Allen, who's the founder and chief strategy officer for MendIt, has worked a decade in ESG consulting. Photo via mendit.app

“I learned about how the throw-away culture and fast fashion — the mass production of extraordinarily cheap textiles — leads to all these really humongous environmental problems,” Allen says, citing that the equivalent of a garbage truck full of textiles is landfilled or incinerated every second around the globe.

“It’s a really huge problem, but we don’t really see it in our culture,” Allen continues. “One of the simple things we can do to make an impact is to extend the life of the clothes we already own — mend them, take care of the, and don’t just throw them away after three months.”

In light of this research and the unmet need Allen saw from her own experience, she founded MendIt, a Houston startup that connects users digitally to the local seamstresses and menders. Her first idea of the company was to tap into the gig economy and “Uber-ize” the industry. But she quickly realized there was an opportunity to tap into the small businesses already working within this space. These businesses are usually not digitally savvy and usually women and immigrant-owned. While these businesses already exist, they aren’t tapping into the market need as best as they could, Allen says.

“There’s a disconnect. There’s a market of people who potentially want to mend their clothes, but there’s no easy way of finding or accessing that service,” she says. “With this next generation, you need to meet them where they are.”

And where they are, Allen says, is on their phones.

MendIt is completing a pilot program with one mender — Connect Community in Gulfton area — in partnership with St. Luke's Gethsemane on Bellaire in Sharpstown. She also hopes to tap into a local artist who can help with customization — like embroidery, for instance.

MendIt hopes to take the lessons learned from this pilot and expand within Houston before growing nationally. She’s also looking for partners — menders, retailers, and potential investors — down the road to further grow the business.

“The broader vision is to have every small business in the Unite States that does clothing repair or customization will be registered on the app so that local users can find them where they live and place orders through the app,” she says.

The MendIt app is available now as a part of the company's pilot program. Photo via mendit.app

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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