4 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Sarah Essama of Teach for America Houston, Scott Schneider of HTX Labs, and Drs. Maria Elena Bottazzi and Peter Hotez. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to four local innovators across industries — from health tech to software — recently making headlines in Houston innovation.

Sarah Essama, director of social innovation at Teach For America Houston

Sarah Essama of Teach For America Houston shares how she innovated a new way for students themselves to learn how to innovate. Photo courtesy of Sarah Essama

As director of social innovation at Teach For America Houston, it's Sarah Essama's job to come up with new ways for the organization to support both students and teachers. But, as she explains on the Houston Innovators Podcast this week, Essama realized a huge lesson modern students needed was to learn this innovation process themselves.

This line of thinking turned into Essama founding The Dream Lab, powered by Teach for America Houston.

"The Dream Lab is a set of immersive design spaces where young people leverage their imagination and creativity to innovate and solve problems within their community," she explains.

Last month, the new concept rolled out to high school students in partnership with DivInc Houston, a nonprofit focused on social and economic equity in entrepreneurship, and 21 ninth graders spent the day at the Ion for a mini-innovation accelerator and design showcase. Click here to read more.

Scott Schneider, CEO and founder of HTX Labs

Scott Schneider of HTX Labs has something to celebrate. Photo via htxlabs.com

A Houston-based virtual reality training provider has closed its first round of funding. HTX Labs announced last month that it has received a $3.2 million investment from Cypress Growth Capital.

“We have been looking to secure outside capital to accelerate the growth of our EMPACT platform and customer base but we hadn’t found the right partner who provided an investment vehicle that matched our needs,“ says HTX Labs CEO Scott Schneider in the release. “We found everything we were looking for in Cypress Growth Capital. They have a non-dilutive funding model that aligns with our capital expectations and have the level of experience that really makes this smart money.

The fresh funding will go toward growing and scaling the company's operations — both within the current Department of Defense and expansion opportunities into key commercial markets, like heavy industry, manufacturing, and higher education. Additionally, the funding will support increased customer adoption. Click here to read more.

Drs. Maria Elena Bottazzi and Peter Hotez

Two Houston health care innovators got the green light to distribute their low-cost COVID-19 vaccine in Indonesia. Photo courtesy of TMC

After months of development and testing, the Houston-born COVID-19 vaccine has gotten the go-ahead to be produced and distributed in Indonesia.

IndoVac was created by the Texas Children’s Hospital Center for Vaccine Development and Baylor College of Medicine. Drs. Peter Hotez and Maria Elena Bottazzi lead the vaccine project. Bio Farma is licensing IndoVac from BCM Ventures, the commercial group at the Baylor College of Medicine.

“Access to vaccines in the developing world is critical to the eradication of this virus,” Hotez, co-director of the Texas Children’s Hospital Center for Vaccine Development and dean of the National School of Tropical Medicine at Baylor College of Medicine, says in a news release. Click here to read more.

Drs. Maria Elena Bottazzi and Peter Hotez got the green light to distribute their low-cost COVID-19 vaccine in Indonesia. Photo courtesy

Houston doctors get approval for low-cost COVID vaccine abroad

green light

A Houston-born COVID-19 vaccine has gotten the go-ahead to be produced and distributed in Indonesia.

PT Bio Farma, which oversees government-owned pharmaceutical manufacturers in Indonesia, says it’s prepared to make 20 million doses of the IndoVac COVID-19 vaccine this year and 100 million doses a year by 2024. This comes after the vaccine received authorization from the Indonesian Food and Drug Authority for emergency use in adults.

With more than 275 million residents, Indonesia is the world’s fourth most populous country.

Aside from distributing the vaccine in Indonesia, Bio Farma plans to introduce it to various international markets.

“The need for a safe, effective, low-cost vaccine for middle- to low-income countries is central to the world’s fight against the COVID-19 pandemic,” says Bottazzi, co-director of the Texas Children’s Hospital Center for Vaccine Development and associate dean of the National School of Tropical Medicine at Baylor.

“Without widespread inoculation of populations in the developing world, which must include safe, effective booster doses, additional [COVID-19] variants will develop, hindering the progress achieved by currently available vaccines in the United States and other Western countries.”

Bio Farma says it has completed Phase 1 and Phase 2 clinical trials for IndoVac and is wrapping up a Phase 3 trial.

IndoVac is a version of the patent-free, low-cost Corbevax vaccine, developed in Houston and dubbed “The World’s COVID-19 Vaccine.” The vaccine formula can be licensed by a vaccine producer in any low- or middle-income country, which then can take ownership of it, produce it, name it, and work with government officials to distribute it, Hotez told The Texas Tribune in February.

Among donors that have pitched in money for development of the vaccine are the Houston-based MD Anderson and John S. Dunn foundations, the San Antonio-based Kleberg Foundation, and Austin-based Tito’s Vodka.

“During 2022, we hope to partner with the World Health Organization and other United Nations agencies to vaccinate the world. We believe that global vaccine equity is finally at hand and that it is the only thing that can bring the COVID pandemic to an end,” Hotez and Bottazzi wrote in a December 2021 article for Scientific American.

Dr. Peter Hotez and Dr. Maria Elena Bottazzi have been recognized by Fast Company for their leadership in developing low-cost COVID vaccine. Photo courtesy of Texas Children's

Houston doctors recognized among top creative leaders in business

winners

This week, Fast Company announced its 14th annual list of Most Creative People in Business — and two notable Houstonians made the cut.

Dr. Peter Hotez and his fellow dean of the National School of Tropical Medicine at Baylor College of Medicine, Dr. Maria Elena Bottazzi, were named among the list for “open sourcing a COVID-19 Vaccine for the rest of the world.” The list, which recognizes individuals making a cultural impact via bold achievements in their field, is made up of influential leaders in business.

Hotez and Bottazzi are also co-directors for the Texas Children's Hospital's Center for Vaccine Development -one of the most cutting-edge vaccine development centers in the world. For the past two decades it has acquired an international reputation as a non-profit Product Development Partnership (PDP), advancing vaccines for poverty-related neglected tropical diseases (NTDs) and emerging infectious diseases of pandemic importance. One of their most notable achievements is the development of a vaccine technology leading to CORBEVAX, a traditional, recombinant protein-based COVID-19 vaccine.

"It's an honor to be recognized not only for our team's scientific efforts to develop and test low cost-effective vaccines for global health, but also for innovation in sustainable financing that goes beyond the traditional pharma business model," says Hotez in a statement.

The technology was created and engineered by Texas Children's Center for Vaccine Development specifically to combat the worldwide problem of vaccine access and availability. Biological E Limited (BE) developed, produced and tested CORBEVAX in India where over 60 million children have been vaccinated so far.

Earlier this year, the doctors were nominated for the 2022 Nobel Peace Prize for their research and vaccine development of the vaccine. Its low cost, ease of production and distribution, safety, and acceptance make it well suited for addressing global vaccine inequity.

"We appreciate the recognition of our efforts to begin the long road to 'decolonize' the vaccine development ecosystem and make it more equitable. We hope that CORBEVAX becomes one of a pipeline of new vaccines developed against many neglected and emerging infections that adversely affect global public health," says Bottazzi in the news release from Texas Children's.

Fast Company editors and writers research candidates for the list throughout the year, scouting every business sector, including technology, medicine, engineering, marketing, entertainment, design, and social good. You can see the complete list here

Dr. Maria Elena Bottazzi and Dr. Peter Hotez have been nominated for their low-cost COVID vaccine. Photo courtesy of Baylor College of Medicine

2 Houston doctors nominated for Nobel Peace Prize for low-cost COVID vaccine

major moment

He’s gained national and global acclaim for his battle against COVID-19 and for his efforts, Houston’s Dr. Peter Hotez has been nominated for the 2022 Nobel Peace Prize.

Hotez, and his fellow dean of the National School of Tropical Medicine at Baylor College of Medicine, Dr. Maria Elena Bottazzi, were nominated for the iconic award by Houston Congresswoman Lizzie Fletcher (Texas-07).

The duo, who are also co-directors of the Center for Vaccine Development at Texas Children’s Hospital, were cited in a letter to the Norwegian Nobel Committee for their work to develop and distribute the low-cost Corbevax vaccine to people of the world — without patent limitation.

“My hope is that the nomination not only recognizes the importance of reducing global vaccine inequities and inequalities, but also raises the awareness regarding the importance of vaccines as lifesaving interventions and combating vaccine hesitancy in the US and globally,” Hotez tells CultureMap.

As ABC13 reports, the Nobel nominations were due Monday, January 31. In March, a shortlist is prepared and then reviewed between April and August. The winners are announced in early October and they receive their awards in Oslo, Norway on December 10.

“Dr. Hotez and Dr. Bottazzi’s effort to develop the Corbevax vaccine is truly one of international cooperation and partnership to bring health, security, and peace around the world by creating a COVID-19 vaccine and making it available and accessible to all,” Fletcher said in a statement. “It is a contribution that is of the greatest benefit to humankind.”

Hotez, one of CultureMap’s most-talked-about Houstonians in 2021, added in a statement: “I am honored that Congresswoman Fletcher would nominate us for the Nobel Peace Prize. Dr. Bottazzi and I have worked together for years, and our purpose has never changed — to bring attention to the neglected diseases of poverty and build a new generation of vaccine in the pursuit of global vaccine diplomacy. With our COVID vaccine, which is inexpensive and easy to produce, our intent was to make it available to millions of people in the world who would otherwise not have access to COVID vaccines.”

“When the COVID pandemic hit, we wanted to make a difference and had great confidence our coronavirus vaccine technology, previously developed, could lead to a global solution,” Bottazzi added. “Hopefully, it will be game changing for many countries.”

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This article originally ran on CultureMap.

Drs. Maria Elena Bottazzi and Peter Hotez at the Center for Vaccine Development. Photo courtesy of Texas Children's Hospital

2 Houston powerhouses deploy game-changing COVID-19 worldwide vaccine

a good shot

With the U.S. logging its highest single-day total of new COVID-19 cases (441,278 infections) and some 281, 808, 270 cases documented worldwide, new treatments worldwide are in major demand — especially in emerging nations.

To that end, Texas Children’s Hospital and Baylor College of Medicine announced a new COVID vaccine ready to deploy in India and soon, other underserved countries.

Corbevax, which is dubbed “The World’s COVID-19 Vaccine,” utilizes a traditional recombinant protein-based technology that will enable production at large scales, per a press release. That means the inoculation will be widely accessible to inoculate the global population.

This new vaccine was developed at Texas Children’s Hospital CVD and led by co-directors Drs. Maria Elena Bottazzi and Peter Hotez — and in-licensed from BCM Ventures, Baylor College of Medicine’s integrated commercialization team, to Hyderabad-based vaccine and pharmaceutical company Biological E. Limited (BE).

After completing two Phase III clinical trials involving more than 3000 subjects the vaccine was found to be safe, well tolerated, and immunogenic. Current research shows Corbevax notably effective against the Ancestral-Wuhan strain and the globally dominant Delta variant, press materials note.

Safe, streamlined, low-cost vaccines for middle- to low-income countries are central to the world’s fight against the COVID-19 pandemic, the two Houston organizations note. Indeed, without widespread vaccination of populations in the Global South, additional virus variants will arise, hindering the progress achieved by currently available vaccines in the United States and other Western countries, per research.

“This announcement is an important first step in vaccinating the world and halting the pandemic,” said Hotez in a statement. “Our vaccine technology offers a path to address an unfolding humanitarian crisis, namely the vulnerability the low- and middle-income countries face against the delta variant. Widespread and global vaccination with our Texas Children’s-Baylor-BE vaccine would also forestall the emergence of new variants. We have previously missed that opportunity for the alpha and delta variant. Now is our chance to prevent a new global wave from what might follow.”

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This article originally ran on CultureMap.

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Who are Houston's top innovators? Nominate now for 2026 Houston Innovation Awards

Calling All Innovators

Calling all Houston innovators: The 2026 Houston Innovation Awards, presented by InnovationMap, return this fall to celebrate the best and brightest in the Houston innovation ecosystem right now.

We're asking you to nominate Houston's top innovators and startups for this year's awards. Nominations are open now through August 27 and can be made on behalf of yourself, your organization, and other influential leaders in the local innovation scene.

The annual awards program recognizes the most innovative individuals and companies in Houston across 10 prestigious categories.

This year's awards will honor the following categories:

Minority-founded Business, honoring an innovative startup founded or co-founded by BIPOC or LGBTQ+ representation.
Female-founded Business, honoring an innovative startup founded or co-founded by a woman.
Energy Transition Business, honoring an innovative startup providing a solution within renewables, climatetech, clean energy, alternative materials, circular economy, and beyond.
Health Tech Business, honoring an innovative startup within the health and medical technology sectors.
Deep Tech Business, honoring an innovative startup providing technology solutions based on substantial scientific or engineering challenges, including those in the AI, robotics, and space sectors.
Startup of the Year (People's Choice), honoring a startup celebrating a recent milestone or success. The winner will be selected by the community via an interactive voting experience.
Scaleup of the Year, honoring an innovative later-stage startup that's recently reached a significant milestone in company growth.
Incubator/Accelerator of the Year, honoring a local incubator or accelerator that is championing and fueling the growth of Houston startups.
Mentor of the Year, honoring an individual who dedicates their time and expertise to guide and support budding entrepreneurs.
Trailblazer, honoring an innovator who's made a lasting impact on the Houston innovation community.

You have three weeks to submit nominees, so don't delay — nominate today at this link or fill out the form below. Qualified nominees will receive a formal application to complete, which will be reviewed by our esteemed panel of judges to determine the finalists and winners.

More announcements about the 2026 Houston Innovation Awards are coming soon, including an introduction to this year's panel of judges. Interested in sponsoring the 2026 Houston Innovation Awards? Please contact sales@innovationmap.com.

KBR unveils name, branding for new government services spinoff

new identity

Houston-based KBR Inc.'s new Mission Technology Solutions unit officially has a name.

The previously announced government services spinoff, which until now has been nicknamed SpinCo, will now be known as Trinzic. The company said in a news release that the name was inspired by the word intrinsic, "reflecting essential, built-in capabilities and deep expertise operating in some of the world’s most complex and mission-critical environments."

New York-based firm Siegel + Gale developed the company's new brand. In addition to the new name, the company shares that its new logo will feature a stylized letter N, with brand colors in orange and gray.

“Trinzic represents who KBR Mission Tech has always been at our core: an essential partner bringing innovation and trusted execution to the missions that matter most,” Stuart Bradie, KBR President and CEO, said in the release. “The new Trinzic brand represents both our strong heritage and the tremendous opportunity ahead. Our teams aim to deliver solutions that address some of the world’s most critical national priorities every day, and this new identity captures the purpose-driven culture and mission focus that we expect to continue to define the company moving forward.”

KBR expects the spin-off to be completed in January 2027. At that time, Trinzic will operate as an independent, publicly traded company that will focus on technology and engineering services for the space and national security sectors.

KBR will remain a separate publicly traded company that will focus on sustainable technology and services to support the energy transition. KBR first announced the spinoff plans in October 2025.

Last month, KBR announced two C-suite hires for Trinzic, or what was then known as SpinCo.

Michael LaRouche will serve as Trinzic's inaugural president and CEO. LaRouche is currently CEO of Serco North America, a Virginia-based government services contractor. Nicholas Veasey, current CFO of Virginia-based MAG Aerospace, was named Trinzic's CFO. Bradie will remain chairman, president and CEO of KBR.

Rice lands $19 million grant to build AI-driven quantum materials lab

Quantum Boost

Rice University has received a $19.9 million award from the National Science Foundation to increase the production of quantum and electronic materials by using a combination of artificial intelligence, cloud-based labs and robotics.

The four-year project will create a remote and automated research platform that aims to accelerate discovery and the testing process, according to Rice. The aptly titled project, "Revolutionizing AI-Driven Autonomous Experimentation for Next-Generation Semiconductor Synthesis” (READINESS), will be led by Rice materials scientist Jun Lou, who serves as principal investigator. SUNY Polytechnic Institute and the University of Texas at Austin will collaborate with Rice on the project.

At first, READINESS will focus on two-dimensional materials, oxide semiconductors and diamond thin films that can support emerging technologies, like quantum devices.

READINESS is one of 20 projects selected for the NSF's Programmable Cloud Laboratories Test Bed initiative, which aims to provide more U.S. researchers with access to automated scientific tools.

Additionally, the project aligns with the Department of Energy’s Genesis Mission, which recently selected four projects from Houston universities and companies, including two from Rice. The national initiative aims to unite government, industry, academia and philanthropy to lead to breakthroughs in energy, scientific discovery and national security.

READINESS will offer more advanced lab systems remotely via a cloud interface to assist startups, other research groups, and companies that don’t have the resources, staffing or equipment to produce quantum materials and advanced electronics. READINESS will also allow researchers to simulate experiments via virtual experiments or digital twins before they conduct the physical experiment.

Rice says this will be particularly useful in quantum materials research, which is often met with barriers— like the adjustments of chemical composition, gas flow, pressure, and temperature—that can change the properties of a material.

“This project will give researchers access to capabilities that have traditionally been available only in a handful of laboratories,” David Sholl, executive vice president for research at Rice, said in a news release. “By lowering those barriers, READINESS can accelerate discovery and expand who can participate in cutting-edge materials research.”

Additionally, the project’s AI aspect will offer recommendations for new tests, recognize safety limits and analyze results to assist researchers.

“Responsible AI should complement researchers’ capabilities rather than replace their judgment,” Luay Nakhleh, Dean of Rice’s George R. Brown School of Engineering and Computing, added in the release. “READINESS embodies this principle by combining automated systems with transparency, safeguards and human oversight at critical decision points.”

READINESS’ lab will be based out of Rice’s Ralph S. O’Connor Building for Engineering and Science. Partner sites will also contribute equipment, expertise and workforce development programs, according to Rice.

Ultimately, READINESS aims to elevate the speed, reliability and reproducibility of experiments, and to promote access to automated scientific tools for U.S. researchers.

“Our goal is to create a laboratory that researchers from across the country can use to produce advanced electronic and quantum materials on demand,” Lou added in the release. “By integrating robotics, AI and digital twins, we aim to learn from every experiment and shorten the pathway from scientific discovery to practical technology.”

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