Eli Lilly to build $6.5B pharmaceutical factory at Generation Park

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Eli Lilly is expected to bring a $6.5 billion manufacturing facility to Houston by 2030. Rendering courtesy Greater Houston Partnership.

Pharmaceutical giant Eli Lilly and Co. plans to build a $6.5 billion manufacturing plant at Houston’s Generation Park. More than 300 locations in the U.S. competed for the factory.

The Houston site will be the first major pharmaceutical manufacturing plant in Texas, according to the Greater Houston Partnership.

Lilly said it plans to hire 615 full-time workers for the 236-acre plant, including engineers, scientists and lab technicians. The company will collaborate with local colleges and universities to help build its talent pipeline.

The plant will also generate an estimated 4,000 construction jobs.

Lilly said every dollar it spends in the Houston area will contribute an additional $4 to the local economy.

“This is a transformative moment for the Houston region and our life sciences industry,” Steve Kean, president and CEO of the Greater Houston Partnership, said in a release. “The Lilly project represents one of the largest for-profit life sciences investments in Texas history and is a powerful endorsement of Houston’s growing position as a global hub for innovation, advanced manufacturing, and biomedical excellence.”

The factory, expected to go online by 2030, will make small-molecule medicines for fields such as oncology, immunology and neuroscience. Perhaps most notably, the site will manufacture orforglipron, Lilly's first oral small-molecule GLP-1 medicine for treatment of obesity and type 2 diabetes. The drug is currently undergoing clinical trials.

“Our new Houston site will enhance Lilly’s ability to manufacture orforglipron at scale and, if approved, help fulfill the medicine’s potential as a metabolic health treatment for tens of millions of people worldwide who prefer the ease of a pill that can be taken without food and water restrictions,” David Ricks, chairman and CEO of Lilly, said in a release.

The company said it chose Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, because of factors such as financial incentives, access to utilities and transportation, and the region’s business-friendly environment. Generation Park is home to campuses for San Jacinto College and Lone Star College.

The plant will be outfitted with machine learning, AI, advanced data analytics, digital automation, and similar tools to streamline operations, Lilly said.

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Seven student-founded startups pitched their business plans at an annual NASA event. Photo via NASA.gov

Student startups pitch out-of-this-world tech at Houston competition

space tank

Several groups of students from all over the United States tapped into technology developed by NASA to create business plans. The teams competed in Houston last week for thousands of dollars, and one team went home with the win.

NASA’s Minority University Research and Education Project, or MUREP, hosted its annual "Space Tank" pitch event, MUREP Innovation and Technology Tech Transfer Idea Competition, or MITTIC, last week at Space Center Houston. Seven teams from across the country — including three Texas teams — pitched business plans based on NASA-originated technology.

“Students and faculty members of MITTIC are notably engaging with our agency, but they are helping to fulfill our mission to make the earth a better, safer place creating products and services that will shape the future," says Donna Shafer, associate director at Johnson Space Center.

All seven teams — each led by a minority student — went home with at least $5,000 as a prize for making it to the finals, but one team from the University of Massachusetts at Boston took home first place and a $10,000 prize. The winning team is also invited to join Team Piezo Pace from the University of St. Thomas, Houston, in a visit to NASA’s Ames Research Center in Silicon Valley, California, for additional look in the innovation and entrepreneurial space.

The judges for the event included: Hope Shimabuku, director of the U.S. Patent and Trademark Office for the Texas Region; Megan Ortiz, project manager at NASA; Lawrence Cosby, vice president of IP strategy at JPMorgan Chase & Co; Terik Tidwell, director of inclusive innovation at VentureWell; Jorge Valdes, program advisor on STEM education and intellectual property at the United States Patent and Trademark Office; Walt Ugalde, economic development executive at NASA; and Laura Barron, autonomous systems technology deputy project manager at NASA.

The seven finalist teams — and the technology they are working on — are as follows:

  • Lone Star College - CyFair’s team Aquarius Solutions, which pitched its water purification product, ClearFlow, based off an ammonia removal system developed at NASA
  • Fayetteville State University in North Carolina’s ASAPA team pitched their Autonomous Solar Array Assembly drone technology that’s based on NASA’s Print-assisted Photovoltaic Assembly system for automated printing of solar panels.
  • University of Houston-Clear Lake’s team AstroNOTS has identified a technology to address the safety of wildfire rescue teams. The PyroCap is a emergence fire shelter based on NASA’s Lightweight Flexible Thermal Protection System.
  • Santa Monica College in California’s team, BREATHE, pitched a noninvasive technology to replace traditional mammograms. The device can analyze breath through a NASA-designed sensor.
  • University of Massachusetts-Boston’s winning team, LazerSense Solutions, is working on a technology for smoke and gas detection. The PartaSense device can detect everything from carbon monoxide to black mold. It’s based on NASA’s MPASS IP.
  • Hartnell College in California’s team PanterBotics is working on an zero-emission electric vehicle, the OmniZero, to address climate change. The technology, a modular robotic vehicle, originated at NASA.
  • University of Texas at Austin’s Longhorn Innovators, who pitched a thinking cap technology to increase and enhance focus. The wearable device is based on NASA technology ZONE, or Zeroing Out Negative Effects, an analysis from EEG sensors.

A new initiative from the city of Houston and Hertz aims to boost Houston's electric vehicle rental fleet. Photo via Mayor Sylvester Turner/Facebook

This new partnership will triple Houston's electric vehicle rental fleet

seeing green

A new partnership between The Hertz Corp. and the City of Houston will bring 2,100 rental electric vehicles to Houston, according to an announcement from the organizations earlier this week.

Dubbed Hertz Electrifies Houston, the program aims to boost Houston's EV rental fleet, as well add to the city's charging infrastructure and EV education and training opportunities.

The new vehicles will come from automakers Tesla, Polestar, and GM and can be rented to leisure and business customers, as well as rideshare drivers.

In partnership with bp pulse, Hertz Electrifies Houston will also bring a new EV fast-charging hub to Hobby Airport that's designed to serve ride-hail, taxi fleets and the general public.

"Our goal is to convert all non-emergency, light-duty municipal vehicles to electric by 2030," Mayor Sylvester Turner says in a statement. "This partnership with Hertz will provide an invaluable boost to achieve this goal and the goal of our Climate Action Plan for Houston to be a net-zero city by 2050."

In addition to the new fleet and charging hub, Hertz announced it will also donate an EV to Lone Star College-North Harris to help the college provide EV training to students in its auto servicing curriculum.

"Lone Star College-North Harris houses one of top automotive programs in Texas," Archie Blanson, president of Lone Star College-North Harris, says in the statement. "To make our students competitive and meet industry demand, we must ensure we are bringing the latest technologies, including a diversified fleet of EVs into the classroom.”

Earlier this month, Hertz also launched a Hertz Electrifies program in Denver. The initiative aims to bring 5,200 rental EVs to Denver. In 2022, the company first announced its plan to partner with bp pulse to install a national network of EV charging solutions for its customers.

Houston also has grown into a hub for EV and EV charging innovation recently. Houston-based Zeta Energy is leading efforts to develop efficient EV batteries, and received $4 million in funding from the U.S. Department of Energy's ARPA-E Electric Vehicles for American Low-Carbon Living, or EVs4ALL, program earlier this year.

Houston's Revterra has also created a kinetic energy storage system that enables rapid EV charging. The company’s founder and CEO, Ben Jawdat, spoke about the energy transition on the Houston Innovators Podcast last month.
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Houston scientist wins prestigious Pew Scholar award for brain cancer research

standout scholar

Christina Tringides, an assistant professor of materials science and nanoengineering at Rice University, is one of 21 scientists to win a prestigious Pew Biomedical Scholar award.

She is the first faculty member from Rice to win the distinction, which provides $300,000 over four years for advances in biomedicine, according to the university. The awards are granted to researchers who are in the first few years at the assistant professor level.

In Tringides’ case, the funding will support her innovative new method of modeling glioblastoma, a common and extremely aggressive form of brain cancer. Thanks to producing its own blood supply, glioblastoma spreads quickly, weaving tendrils of blighted tissue throughout the brain. Because of this, surgery is difficult and conventional therapies ineffective.

Understanding the way glioblastoma spreads is crucial to the search for a cure. Tringides is using hydrogels that mimic the brain’s extracellular matrix. Using cultures and a microscopic labyrinth, her team can see how the cancer spreads, bonds with neurons and changes cell wall activity. Essentially, Tringides has devised an intelligence test for tumors in hopes of learning how to outsmart them.

“As cancer crawls through the maze, we can look at how it is interacting with the neurons more and more, and measure how electrical activity is changing as a result,” she said in a news release from Rice.

Examining how cancer cells grow can reveal which conditional changes slow them down. Finding ways to alter the structure of brain matter in a way that makes it inhospitable to the cancer could lead to therapies that would impede growth or even reverse it. Using her custom-made ersatz brain maze makes it easier to observe changes than it would be in a patient’s brain.

“Imaging synapses is time-intensive ⎯ it can involve large data files that are hard to visualize, but if we know that the only place where we might have a synapse is this tiny 1-by-4-by-10 micron channel, it makes it much faster and reliable to image them,” Tringides said.

Born in Ames, Iowa, Tringides received her doctorate in biophysics from Harvard before joining Rice in 2024 through a Cancer Prevention and Research Institute of Texas (CPRIT) recruitment award.

Her research was also one of the first four projects to receive research awards through the Rice Brain Institute and TMC Neuro Collaboration Seed Grant Program.

Texas residents earn 11th highest income in U.S., says 2026 study

Money Matters

A new WalletHub study comparing income disparities across America has ranked Texas residents No. 11 on the list of states with the highest earning residents in the nation.

The report, "States Where People Have the Highest Income (2026)," analyzed U.S. Census Bureau income data in all 50 states and the District of Columbia. The report evaluated the average annual income of the top five percent, the median annual household income, and the average annual income of the bottom 20 percent of residents in every state, all adjusted for the cost of living.

The report's data revealed the top five percent of Texans, the highest earners, make $520,378 on average yearly after adjusting for the cost of living. That's the seventh-highest income among the top five percent of earners nationwide.

Meanwhile, the median annual income of a Texas household is just under $76,000. The bottom 20 percent of Texas residents make $17,651 a year, the report found.

For additional context, the latest data from the Federal Reserve shows an American household's median yearly income is about $83,700. WalletHub analyst Chip Lupo also found that the highest earning 10 percent of individuals in the U.S. earn over 12 times more than those in the lowest-earning 10 percent, based on the latest Census data.

"By measuring the income of various percentiles against a state's median income, we can better identify where income disparities are more prevalent, which could help us better understand why residents of certain states struggle more to make ends meet," said Lupo.

Virginia is the state where residents earn the highest income in the U.S., WalletHub said. Based on the report's findings, the top five percent of Virginians make $545,097 on average per year after adjusting for the cost of living. The median annual income of a Virginia household comes out to $95,339, and the bottom 20 percent of residents make $19,671 annually on average.

Conversely, West Virginia is the state where people have the lowest income in the U.S. A West Virginia household makes a median annual income of $56,610, the third-lowest nationally, and the bottom 20 percent of residents make $13,260 on average per year, which is the fifth-lowest in the nation. The top five percent of West Virginians make $372,218 on average per year.

The top 10 states where residents have the highest income are:

  • No. 1 – Virginia
  • No. 2 – New York
  • No. 3 – New Jersey
  • No. 4 – Washington
  • No. 5 – Connecticut
  • No. 6 – Utah
  • No. 7 – Colorado
  • No. 8 – Minnesota
  • No. 9 – Illinois
  • No. 10 – Massachusetts

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This article originally appeared on CultureMap.com.

23 Houston companies rank among America’s most future-ready businesses

future focused

By one measure, Spring-based tech giant Hewlett Packard Enterprises reigns as the most future-ready Houston-area company on the S&P 500 stock index.

HPE sits at No. 72 in a first-time ranking of the best S&P 500 companies for the future. Including HPE, 23 Houston-area companies appear on the list.

Published by The Wall Street Journal, the ranking was created by Bendable Labs for the WSJ Leadership Institute. It evaluates how S&P 500 companies stack up in six areas: AI readiness, innovation, talent readiness, financial fitness, resilience and agility. To be ranked, a company had to be part of the S&P 500 as of Dec. 31.

Among the six categories, HPE ranked highest for innovation (No. 30) among local companies. The WSJ didn’t say why HPE scored so well for innovation. However, the company stands out in this category thanks to:

  • Creation of the El Capitan and Frontier supercomputing systems
  • Research into photonic computing and quantum networking
  • Last year’s $14 billion acquisition of Juniper Networks, giving HPE an edge in AI-native networking
  • Establishment of the everything-as-a-service GreenLake hybrid cloud platform for data centers, colocation facilities and edge computing environments

In an interview with the Six Five podcast at HPE Discover 2025 in Las Vegas, CEO Antonio Neri said the company’s strategy is “basically founded on innovation, and that innovation drives shareholder value over the long term.”

While HPE fared well in the innovation category, it ranked toward the bottom for financial fitness. What’s behind the No. 430 ranking in the financial category? HPE’s low score likely reflects a debt-heavy acquisition strategy coupled with a historically low-margin hardware business.

Here’s the full list of the 23 Houston-area companies included in the ranking of the best companies for the future:

  • No. 72 Hewlett Packard Enterprise
  • No. 105 SLB
  • No. 120 Baker Hughes
  • No. 125 ConocoPhillips
  • No. 158 NRG Energy
  • No. 176 Targa Resources
  • No. 185 Chevron
  • No. 195 Halliburton
  • No. 223 Coterra Energy
  • No. 229 Waste Management
  • No. 235 Exxon Mobil
  • No. 250 Kinder Morgan
  • No. 257 Quanta Services
  • No. 276 CenterPoint Energy
  • No. 285 Sysco
  • No. 313 Occidental Petroleum
  • No. 318 Camden Property Trust
  • No. 333 EOG Resources
  • No. 365 LyondellBasell Industries
  • No. 373 Comfort Systems USA
  • No. 401 Crown Castle
  • No. 408 Phillips 66
  • No. 500 APA
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