Eli Lilly to build $6.5B pharmaceutical factory at Generation Park

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Eli Lilly is expected to bring a $6.5 billion manufacturing facility to Houston by 2030. Rendering courtesy Greater Houston Partnership.

Pharmaceutical giant Eli Lilly and Co. plans to build a $6.5 billion manufacturing plant at Houston’s Generation Park. More than 300 locations in the U.S. competed for the factory.

The Houston site will be the first major pharmaceutical manufacturing plant in Texas, according to the Greater Houston Partnership.

Lilly said it plans to hire 615 full-time workers for the 236-acre plant, including engineers, scientists and lab technicians. The company will collaborate with local colleges and universities to help build its talent pipeline.

The plant will also generate an estimated 4,000 construction jobs.

Lilly said every dollar it spends in the Houston area will contribute an additional $4 to the local economy.

“This is a transformative moment for the Houston region and our life sciences industry,” Steve Kean, president and CEO of the Greater Houston Partnership, said in a release. “The Lilly project represents one of the largest for-profit life sciences investments in Texas history and is a powerful endorsement of Houston’s growing position as a global hub for innovation, advanced manufacturing, and biomedical excellence.”

The factory, expected to go online by 2030, will make small-molecule medicines for fields such as oncology, immunology and neuroscience. Perhaps most notably, the site will manufacture orforglipron, Lilly's first oral small-molecule GLP-1 medicine for treatment of obesity and type 2 diabetes. The drug is currently undergoing clinical trials.

“Our new Houston site will enhance Lilly’s ability to manufacture orforglipron at scale and, if approved, help fulfill the medicine’s potential as a metabolic health treatment for tens of millions of people worldwide who prefer the ease of a pill that can be taken without food and water restrictions,” David Ricks, chairman and CEO of Lilly, said in a release.

The company said it chose Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, because of factors such as financial incentives, access to utilities and transportation, and the region’s business-friendly environment. Generation Park is home to campuses for San Jacinto College and Lone Star College.

The plant will be outfitted with machine learning, AI, advanced data analytics, digital automation, and similar tools to streamline operations, Lilly said.

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Seven student-founded startups pitched their business plans at an annual NASA event. Photo via NASA.gov

Student startups pitch out-of-this-world tech at Houston competition

space tank

Several groups of students from all over the United States tapped into technology developed by NASA to create business plans. The teams competed in Houston last week for thousands of dollars, and one team went home with the win.

NASA’s Minority University Research and Education Project, or MUREP, hosted its annual "Space Tank" pitch event, MUREP Innovation and Technology Tech Transfer Idea Competition, or MITTIC, last week at Space Center Houston. Seven teams from across the country — including three Texas teams — pitched business plans based on NASA-originated technology.

“Students and faculty members of MITTIC are notably engaging with our agency, but they are helping to fulfill our mission to make the earth a better, safer place creating products and services that will shape the future," says Donna Shafer, associate director at Johnson Space Center.

All seven teams — each led by a minority student — went home with at least $5,000 as a prize for making it to the finals, but one team from the University of Massachusetts at Boston took home first place and a $10,000 prize. The winning team is also invited to join Team Piezo Pace from the University of St. Thomas, Houston, in a visit to NASA’s Ames Research Center in Silicon Valley, California, for additional look in the innovation and entrepreneurial space.

The judges for the event included: Hope Shimabuku, director of the U.S. Patent and Trademark Office for the Texas Region; Megan Ortiz, project manager at NASA; Lawrence Cosby, vice president of IP strategy at JPMorgan Chase & Co; Terik Tidwell, director of inclusive innovation at VentureWell; Jorge Valdes, program advisor on STEM education and intellectual property at the United States Patent and Trademark Office; Walt Ugalde, economic development executive at NASA; and Laura Barron, autonomous systems technology deputy project manager at NASA.

The seven finalist teams — and the technology they are working on — are as follows:

  • Lone Star College - CyFair’s team Aquarius Solutions, which pitched its water purification product, ClearFlow, based off an ammonia removal system developed at NASA
  • Fayetteville State University in North Carolina’s ASAPA team pitched their Autonomous Solar Array Assembly drone technology that’s based on NASA’s Print-assisted Photovoltaic Assembly system for automated printing of solar panels.
  • University of Houston-Clear Lake’s team AstroNOTS has identified a technology to address the safety of wildfire rescue teams. The PyroCap is a emergence fire shelter based on NASA’s Lightweight Flexible Thermal Protection System.
  • Santa Monica College in California’s team, BREATHE, pitched a noninvasive technology to replace traditional mammograms. The device can analyze breath through a NASA-designed sensor.
  • University of Massachusetts-Boston’s winning team, LazerSense Solutions, is working on a technology for smoke and gas detection. The PartaSense device can detect everything from carbon monoxide to black mold. It’s based on NASA’s MPASS IP.
  • Hartnell College in California’s team PanterBotics is working on an zero-emission electric vehicle, the OmniZero, to address climate change. The technology, a modular robotic vehicle, originated at NASA.
  • University of Texas at Austin’s Longhorn Innovators, who pitched a thinking cap technology to increase and enhance focus. The wearable device is based on NASA technology ZONE, or Zeroing Out Negative Effects, an analysis from EEG sensors.

A new initiative from the city of Houston and Hertz aims to boost Houston's electric vehicle rental fleet. Photo via Mayor Sylvester Turner/Facebook

This new partnership will triple Houston's electric vehicle rental fleet

seeing green

A new partnership between The Hertz Corp. and the City of Houston will bring 2,100 rental electric vehicles to Houston, according to an announcement from the organizations earlier this week.

Dubbed Hertz Electrifies Houston, the program aims to boost Houston's EV rental fleet, as well add to the city's charging infrastructure and EV education and training opportunities.

The new vehicles will come from automakers Tesla, Polestar, and GM and can be rented to leisure and business customers, as well as rideshare drivers.

In partnership with bp pulse, Hertz Electrifies Houston will also bring a new EV fast-charging hub to Hobby Airport that's designed to serve ride-hail, taxi fleets and the general public.

"Our goal is to convert all non-emergency, light-duty municipal vehicles to electric by 2030," Mayor Sylvester Turner says in a statement. "This partnership with Hertz will provide an invaluable boost to achieve this goal and the goal of our Climate Action Plan for Houston to be a net-zero city by 2050."

In addition to the new fleet and charging hub, Hertz announced it will also donate an EV to Lone Star College-North Harris to help the college provide EV training to students in its auto servicing curriculum.

"Lone Star College-North Harris houses one of top automotive programs in Texas," Archie Blanson, president of Lone Star College-North Harris, says in the statement. "To make our students competitive and meet industry demand, we must ensure we are bringing the latest technologies, including a diversified fleet of EVs into the classroom.”

Earlier this month, Hertz also launched a Hertz Electrifies program in Denver. The initiative aims to bring 5,200 rental EVs to Denver. In 2022, the company first announced its plan to partner with bp pulse to install a national network of EV charging solutions for its customers.

Houston also has grown into a hub for EV and EV charging innovation recently. Houston-based Zeta Energy is leading efforts to develop efficient EV batteries, and received $4 million in funding from the U.S. Department of Energy's ARPA-E Electric Vehicles for American Low-Carbon Living, or EVs4ALL, program earlier this year.

Houston's Revterra has also created a kinetic energy storage system that enables rapid EV charging. The company’s founder and CEO, Ben Jawdat, spoke about the energy transition on the Houston Innovators Podcast last month.
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5 Houston deep tech startups pushing the boundaries of their industries

meet the finalists

Houston has long been at the forefront of innovation, from NASA’s Johnson Space Center to its startup ecosystem using technology to disrupt industries.

As part of the 2026 Houston Innovation Awards, our Deep Tech Business category will honor an innovative startup providing technology solutions based on substantial scientific or engineering challenges, including those in the AI, robotics and space sectors.

Five deep tech companies have been named finalists for the 2026 award.

Read more about these businesses, their founders and their breakthrough technologies below. The 2026 winners will be announced on InnovationMap.com in mid-November.

Casimir

Battery tech startup Casimir develops semiconductor chips that produce continuous electrical power straight from the quantum vacuum, without the need for a battery, cord or external charge source. The company is targeting commercialization for its first-generation MicroSparc chip by 2028.

Harold “Sonny” White founded Casimir in 2023 after nearly two decades at NASA. The company emerged from stealth with a $12 million seed round in 2026. It was also awarded an STTR Phase I contract from the U.S. Space Force's SpaceWERX to support the development of the company's solid-state generator for potential use by the Department of the Air Force earlier this year.

FocisAI

Artificial intelligence startup FocisAI helps refinery owner-operators unlock actionable insights from 3D scans and images.

FocisAI was founded by CEO Tyler Wooten, COO Colin Snell and CTO Kyle Snell in 2026. It is a member of Greentown Labs and launched a seed round in September, which is expected to close by the end of the year, according to the company's application. It has rolled out 10 pilot programs and is looking to move into recurring, facility-scale deployments and scale its team in Houston this year.

Machine Saver Inc.

Industrial tech startup Machine Saver Inc. builds wireless and wired vibration and proximity sensors to tell heavy industry when a machine is about to fail. The company's technology runs on an 8-plus-year battery life and helps operators reduce downtime, improve maintenance and extend equipment life.

Machine Saver was founded by CEO Colton Bach and Quentin Bach in 2013. Its customers and partners include Houston Methodist, Blue Bell, Genemco, as well as energy and heavy industry, food and beverage, and cold chain companies, according to its application. The company is raising a Series A.

Square Robot

Energytech startup Square Robot develops and operates submersible inspection robotics that inspect aboveground storage tanks while they remain in service. The robots reduce downtime and costs, improve worker safety and limit hydrocarbon emissions.

Square Robot launched its Houston office in 2019 and closed a Series B in 2025. It plans to complete its first U.S. Navy demonstrator tank in November and is also developing real-time inspection software.

Venus Aerospace

Spacetech company Venus Aerospace is developing a high-thrust rotating detonation rocket engine (RDRE) that replaces the subsonic combustion used in conventional rocket engines. The RDRE is a compact, simpler engine that can deliver up to 15 percent greater efficiency for defense and space applications. It completed its first U.S. flight test of the engine last summer.

Venus Aerospace was founded in 2020 by CEO Cassie Duggleby and CTO Andrew Duggleby. It raised a $20 million Series A in 2022 and $42 million Series A2 in 2025. It closed a $91 million Series B earlier this year and expanded its leadership team. The company is working toward longer-duration and higher-thrust testing and advancing its flight program.

Houston leads U.S. with the biggest surge in millionaire renters

Rent Report

The number of millionaire renters and homeowners in the U.S. has surged over the last five years, and Houston has soared ahead of the rest with the largest growth rate among these affluent renter households.

Houston leads the nation with the No. 1 increase in millionaire renters from 2020 to 2024, a new RentCafe study found. The number of these wealthy households increased from 18 to 232 over the last five years, representing a 1,189 percent growth rate.

"The pandemic accelerated the shift as remote work pushed the wealthy to relocate to lower-tax metros like Houston, where millionaire renters grew 13-fold, versus 3.9-fold for owners," the report said. "Granted, 232 households is still a tiny fraction of the Houston metro’s roughly 2.7 million households, but the growth rate far outpaces any other major metro."

Nationwide, the number of millionaire renter households grew 229 percent from 2020 to 2024, outpacing the 193 percent growth rate among millionaire homeowners.

Dallas was the only other Texas metro to crack the top 10. The number of millionaire renter households in North Texas has more than quintupled, from just 30 in 2020 to 165 in 2024. That represents a growth rate of 450 percent, which — surprisingly — is only the eighth highest nationwide.

But when it comes to the largest populations of millionaire renters, New York City and San Francisco still lead the way. New York claimed the No. 1 spot with nearly 7,300 millionaire renters living in the city in 2024. Houston ranked 12th on that list.

Elsewhere in Texas, Austin and Dallas ranked as the 16th and 17th, respectively, for the largest population of millionaire renters. There were 206 millionaire renters living in Austin in 2024, and 165 in Dallas.

This is who the typical millionaire renter is
The report also revealed a surprising statistic about the typical millionaire renter in the U.S. — a lot of them are millennials working in "white-collar, high-earning fields."

"Nearly half (49 percent) of millionaire renters are Millennials, and the number of affluent Millennial renter households surged 392 percent during the five-year period," the report said. "Gen X follows with 33 percent of millionaire Gen X households renting after increasing by 147 percent."

The report continued, "Although Gen Z still represents a small share of millionaire renters (just 2 percent of the total), no generation has expanded faster: Gen Z millionaire renter households leaped from fewer than a dozen to more than 400 — a tiny cohort today, but one that was virtually nonexistent five years ago."

The top three most common professions for millionaire renters are chief executives, software developers, and managers, the report additionally found. In Houston, the surge of wealthy newcomers are mostly executives, professional athletes, and entertainers.

"These roles tend to generate steady, substantial income without necessarily tying workers to one location, making renting a practical fit, rather than a financial necessity," the report said.

Hotspots for millionaire homeowners
In RentCafe's separate list comparing the top 10 most popular U.S. metros for millionaire homeowners, Houston ranked 12th nationally with 4,374 millioniare homeowners living in the metro as of 2024. These wealthy Houstonians are most likely working as chief executives, physicians, managers, and lawyers and judges.

Houston has already proven to be a hotspot for millennial homebuyers, and the latest RentCafe data says millennials make up 19 percent of all millionaire homeowners in the U.S. Gen Xers and Baby Boomers still maintain the largest shares of millionaire homeowners nationwide, at 45 and 33 percent, respectively.

Dallas (No. 10) and Austin (No. 20) also appeared among the hottest metros for millionaire homeowners.

Only one Texas city appeared among RentCafe's list of the 20 fastest-growing metros for millionaire homeowners: College Station ranked 13th nationwide with a growth rate of 1,329 percent. From 2020-2024, the number of millionaire homeowners residing in College Station grew from 14 to 200.

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This article originally appeared on CultureMap.com.

Houston ranks high on best cities for small-business expansion report

business growth

For small businesses looking to expand, Houston might be the right place.

Among 56 major U.S. metros, Houston grabbed the No. 6 spot on a new list of the metros boasting the strongest environments for small-business expansion.

A 2025 report from the state comptroller’s office showed roughly 970,000 small businesses operate in the 13-county Gulf Coast region. The region includes the majority of the Houston metro area.

“Whether it’s a family-owned shop on Main Street or a fast-growing startup, small businesses power our state’s economic engine, create opportunity, and strengthen the character of every Texas community,” Kelly Hancock, who was interim state comptroller when the report was released, said in a press release.

Business lending platform Clarify Capital analyzed five factors to develop the list: job growth, business entry and exit, net job creation, and unemployment.

Overall, the Nashville area claimed the No. 1 spot on the list. Other major Texas metros also cracked the top 10, including Austin at No. 3 and Dallas-Fort Worth at No. 7.

“The highest-ranking metros combine labor-market momentum with steady business formation and relatively favorable local employment conditions,” Clarity Capital says.

The Houston metro ranked sixth for job growth, 11th for business entry rate, 38th for business exit rate, second for net job creation rate, and 50th for unemployment rate.

“For business owners, the ranking is a starting point rather than a guarantee,” Clarify Capital says. “Local demand, competition, operating costs, and access to capital still shape whether an expansion works.”

“Building enough cash-flow room for hiring, equipment, and unexpected expenses can help small and midsize business owners take advantage of a strong market without stretching the business too thin,” the company adds.

Of course, money fuels small-business expansion in the Houston area or anywhere else.

According to an analysis of SBA loan data by feasibility consulting firm MMCG, the Houston metro area saw 1,685 approvals for 7(a) loans and 101 approvals of 504 loans in the federal government’s 2025 budget year. The approval numbers for both loan categories increased from the previous year.

Altogether, the 7(a) and 505 loans exceeded $1 billion.

The data from the U.S. Small Business Administration suggests small-business expansion may be on the rise in the Houston area.

Further potential evidence of small-business expansion in the Houston area: The region experienced a 92 percent rise in account applications from 2024 to 2025 submitted to Bluevine, a small-business banking platform. The Houston metro ranked fifth for the number of Bluevine small-business applications in 2025.

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