This week's roundup of Houston innovators includes Emily Keeton of Loeb.nyc, Steve Kean of GHP, and Lacey Tezino of Passport Journeys. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from investing to mental health — recently making headlines in Houston innovation.

Emily Keeton, operating partner and investor of Loeb.nyc

Emily Keeton has worn a lot of hats in Houston's innovation ecosystem and beyond. She shares on the Houston Innovators Podcast how she's engaging with companies these days, what the future holds for Houston, and more. Photo courtesy

Emily Keeton has had a front-row seat as the Houston innovation ecosystem developed — first hands on as a co-founder of Station Houston, and later from outside looking in from New York. As she shared on the Houston Innovators Podcast, she's hopeful about the future of the community.

"I am very optimistic about the future of Houston. It's a long game, and I think people need to keep showing up," she says on the show.

Now based in Houston, her latest endeavor is working with Michael Loeb on Loeb.nyc, a New York-based investment firm with shared services — marketing, design, etc. — with his portfolio. Read more.

Steve Kean, incoming president and CEO of the Greater Houston Partnership

Steve Kean will transition from leading Kinder Morgan to assuming the role of president and CEO of the Greater Houston Partnership later this year. Photo courtesy of the GHP

Steve Kean, who currently serves as the CEO of Kinder Morgan Inc., has been announced as the next president and CEO of the Greater Houston Partnership. He's expected to transition from CEO to board of directors member at Kinder Morgan on August 1. Kean will then assume his new position at GHP no later than Dec. 1.

“I’m grateful for the opportunity to serve our region in this role," he says. "I look forward to building on what Bob, the Board, members, and staff of the Partnership have accomplished. I know first-hand the opportunities that a vibrant business sector can create for people and communities. I look forward to expanding those opportunities further.”

The GHP's outgoing president and CEO, Bob Harvey, announced his retirement earlier this year, and will remain in his position until Kean is onboarded. Read more.

A Houston-founded company is targeting mothers and daughters with their teletherapy app. Photo courtesy of Passport Journeys

When Lacey Tezino’s mother died of cancer she vowed to help other mothers and daughters find their own ways to bond in beautiful, nurturing ways. She turned that vow into a mission that is now available for others to embark on with an online therapy app tailored specifically for the mother-daughter dynamic Passport Journeys.

The app, which launched aptly on Mother's Day, can be downloaded via Apple or Google Play, and includes video therapy sessions, journal opportunities, interactive worksheets, and help those who need access to this form of mental health help with ease.

“Outside of our target audience being mother-daughter, we are also the first teletherapy app to find prescribed activities,“ Tezino tells InnovationMap. “We are the first ones that are actually having the therapist in between their video sessions assign the mother-daughter pair intentional bonding activities. It is meant for them to spend quality time on where they are at in their relationship…there aren’t any other apps that are doing that.” Read more.

Emily Keeton has worn a lot of hats in Houston's innovation ecosystem and beyond. She shares on the Houston Innovators Podcast how she's engaging with companies these days, what the future holds for Houston, and more. Photo courtesy

Long-time innovator shares why she's optimistic about Houston's future as a hub for startups, tech

HOUSTON INNOVATORS PODCAST EPISODE 191

As she describes, Emily Keeton's strength and her curse is that she lacks patience. For this reason, her career, launched originally in investment banking, has taken her from the startup world to media and beyond.

"I'm a person of action, and I think that works well when you work with a startup. You tend to get things done," Keeton says on the Houston Innovators Podcast, adding that she's been called a change agent, and while the terminology isn't her preference, she agrees its an accurate identifier for her. "I can step into a situation, and, after many years of working with so many different companies, I have a lens of pattern recognition of what's worked in the past and potential footfalls. It's what keeps me coming back to startups."

Keeton was one of the founding members of Station Houston — along with John "J.R." Reale, Grace Rodriguez, Blair Garrou, and some other innovators who played a central role in the organization almost a decade ago. The goal was to create a community where startup founders in Houston can go for support from mentors and peers. The organization rolled into into a few entities like the Ion and Capital Factory in 2018.

After her role at Station, Keeton's career took her back to New York, where she worked with WeWork, Mercado, Tempest, and other consumer-facing businesses. She always had one foot still in Houston, until she recently relocated to Houston entirely. She served as COO of Houston Landing, a new nonprofit journalism platform, and her latest endeavor is working with Michael Loeb on Loeb.nyc, a New York-based investment firm with shared services — marketing, design, etc. — with his portfolio.

"I'm based here, and I'll be doing a couple of things, working with a few of the portfolio companies," she says. "And I'm on the lookout for early stage companies here in Texas."

Keeton's perspective, having seen the Houston innovation ecosystem develop — first hands on in Houston, and later from outside looking in from New York — is hopeful. She says that with Station, they realized the power of mentorship — specifically of mentors who have led a startup through scale and exit. Now, Houston just needs more exits and success stories to grow that mentorship base.

"I am very optimistic about the future of Houston. It's a long game, and I think people need to keep showing up," she says on the show.

She adds that what's happening right now is a winter for startups, and she notes that this isn't just something seen in Houston. But this period of time can be an advantage to innovators.

"It's a great time to launch a company," Keeton says, explaining that a few years ago, checks were being written without significant due diligence. Now, this pace has slowed. "It provides a bit of breathing room for people to figure out their business model."

Keeton shares more on her observations of Houston's tech and startup scene and what she looks for in the startups she invests her time and money in on the show. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

---

This article first appeared on EnergyCapitalHTX.com.