3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Emily Keeton of Loeb.nyc, Steve Kean of GHP, and Lacey Tezino of Passport Journeys. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from investing to mental health — recently making headlines in Houston innovation.

Emily Keeton, operating partner and investor of Loeb.nyc

Emily Keeton has worn a lot of hats in Houston's innovation ecosystem and beyond. She shares on the Houston Innovators Podcast how she's engaging with companies these days, what the future holds for Houston, and more. Photo courtesy

Emily Keeton has had a front-row seat as the Houston innovation ecosystem developed — first hands on as a co-founder of Station Houston, and later from outside looking in from New York. As she shared on the Houston Innovators Podcast, she's hopeful about the future of the community.

"I am very optimistic about the future of Houston. It's a long game, and I think people need to keep showing up," she says on the show.

Now based in Houston, her latest endeavor is working with Michael Loeb on Loeb.nyc, a New York-based investment firm with shared services — marketing, design, etc. — with his portfolio. Read more.

Steve Kean, incoming president and CEO of the Greater Houston Partnership

Steve Kean will transition from leading Kinder Morgan to assuming the role of president and CEO of the Greater Houston Partnership later this year. Photo courtesy of the GHP

Steve Kean, who currently serves as the CEO of Kinder Morgan Inc., has been announced as the next president and CEO of the Greater Houston Partnership. He's expected to transition from CEO to board of directors member at Kinder Morgan on August 1. Kean will then assume his new position at GHP no later than Dec. 1.

“I’m grateful for the opportunity to serve our region in this role," he says. "I look forward to building on what Bob, the Board, members, and staff of the Partnership have accomplished. I know first-hand the opportunities that a vibrant business sector can create for people and communities. I look forward to expanding those opportunities further.”

The GHP's outgoing president and CEO, Bob Harvey, announced his retirement earlier this year, and will remain in his position until Kean is onboarded. Read more.

A Houston-founded company is targeting mothers and daughters with their teletherapy app. Photo courtesy of Passport Journeys

When Lacey Tezino’s mother died of cancer she vowed to help other mothers and daughters find their own ways to bond in beautiful, nurturing ways. She turned that vow into a mission that is now available for others to embark on with an online therapy app tailored specifically for the mother-daughter dynamic Passport Journeys.

The app, which launched aptly on Mother's Day, can be downloaded via Apple or Google Play, and includes video therapy sessions, journal opportunities, interactive worksheets, and help those who need access to this form of mental health help with ease.

“Outside of our target audience being mother-daughter, we are also the first teletherapy app to find prescribed activities,“ Tezino tells InnovationMap. “We are the first ones that are actually having the therapist in between their video sessions assign the mother-daughter pair intentional bonding activities. It is meant for them to spend quality time on where they are at in their relationship…there aren’t any other apps that are doing that.” Read more.

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Emily Keeton has worn a lot of hats in Houston's innovation ecosystem and beyond. She shares on the Houston Innovators Podcast how she's engaging with companies these days, what the future holds for Houston, and more. Photo courtesy

Long-time innovator shares why she's optimistic about Houston's future as a hub for startups, tech

HOUSTON INNOVATORS PODCAST EPISODE 191

As she describes, Emily Keeton's strength and her curse is that she lacks patience. For this reason, her career, launched originally in investment banking, has taken her from the startup world to media and beyond.

"I'm a person of action, and I think that works well when you work with a startup. You tend to get things done," Keeton says on the Houston Innovators Podcast, adding that she's been called a change agent, and while the terminology isn't her preference, she agrees its an accurate identifier for her. "I can step into a situation, and, after many years of working with so many different companies, I have a lens of pattern recognition of what's worked in the past and potential footfalls. It's what keeps me coming back to startups."

Keeton was one of the founding members of Station Houston — along with John "J.R." Reale, Grace Rodriguez, Blair Garrou, and some other innovators who played a central role in the organization almost a decade ago. The goal was to create a community where startup founders in Houston can go for support from mentors and peers. The organization rolled into into a few entities like the Ion and Capital Factory in 2018.

After her role at Station, Keeton's career took her back to New York, where she worked with WeWork, Mercado, Tempest, and other consumer-facing businesses. She always had one foot still in Houston, until she recently relocated to Houston entirely. She served as COO of Houston Landing, a new nonprofit journalism platform, and her latest endeavor is working with Michael Loeb on Loeb.nyc, a New York-based investment firm with shared services — marketing, design, etc. — with his portfolio.

"I'm based here, and I'll be doing a couple of things, working with a few of the portfolio companies," she says. "And I'm on the lookout for early stage companies here in Texas."

Keeton's perspective, having seen the Houston innovation ecosystem develop — first hands on in Houston, and later from outside looking in from New York — is hopeful. She says that with Station, they realized the power of mentorship — specifically of mentors who have led a startup through scale and exit. Now, Houston just needs more exits and success stories to grow that mentorship base.

"I am very optimistic about the future of Houston. It's a long game, and I think people need to keep showing up," she says on the show.

She adds that what's happening right now is a winter for startups, and she notes that this isn't just something seen in Houston. But this period of time can be an advantage to innovators.

"It's a great time to launch a company," Keeton says, explaining that a few years ago, checks were being written without significant due diligence. Now, this pace has slowed. "It provides a bit of breathing room for people to figure out their business model."

Keeton shares more on her observations of Houston's tech and startup scene and what she looks for in the startups she invests her time and money in on the show. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


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Houston space org to launch experiments aboard first mission into polar orbit

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Houston's Translational Research Institute for Space Health, or TRISH, will send its latest experiments into space aboard the Fram2 mission, the first all-civilian human spaceflight mission to launch over the Earth’s polar regions.

Fram2, operated by SpaceX, is targeting to launch Monday, March 31, at NASA’s Kennedy Space Center in Florida. The crew of four is expected to spend several days in polar orbit aboard the SpaceX Dragon spacecraft in low Earth orbit. TRISH’s research projects are among 22 experiments that the crew will conduct onboard.

The crew's findings will add to TRISH's Enhancing eXploration Platforms and ANalog Definition, or EXPAND, program and will be used to help enhance human health and performance during spaceflight missions, including missions to the moon and Mars, according to a release from TRISH.

“The valuable space health data that will be captured during Fram2 will advance our understanding of how humans respond and adapt to the stressors of space,” Jimmy Wu, TRISH deputy director and chief engineer and assistant professor in Baylor’s Center for Space Medicine, said in the release. “Thanks to the continued interest in furthering space health by commercial space crews, each human health research project sent into orbit brings us closer to improving crew member well-being aboard future spaceflight missions.”

The six TRISH projects on Fram2 include:

  • Cognitive and Physiologic Responses in Commercial Space Crew on Short-Duration Missions, led by Dr. Mathias Basner at the University of Pennsylvania Perelman School of Medicine. The crew will wear a Garmin smartwatch and a BioIntelliSense BioButton® medical grade device to track cognitive performance, including memory, spatial orientation, and attention before, during, and after the mission.
  • Otolith and Posture Evaluation II, led by Mark Shelhamer at Johns Hopkins University. The experiment will look at how astronauts’ eyes sense and respond to motion before and after spaceflight to better understand motion sickness in space.
  • REM and CAD Radiation Monitoring for Private Astronaut Spaceflight, led by Stuart George at NASA Johnson Space Center. This experiment will test space radiation exposure over the Earth’s north and south poles and how this impacts crew members.
  • Space Omics + BioBank, led by Richard Gibbs and Harsha Doddapaneni at Baylor College of Medicine. The experiment will use Baylor’s Human Genome Sequencing Center's Genomic Evaluation of Space Travel and Research program to gain insights from pre-flight and post-flight samples from astronauts.
  • Standardized research questionnaires, led by TRISH. The test asks a set of standardized research questionnaires for the crew to collect data on their sleep, personality, health history, team dynamics and immune-related symptoms.
  • Sensorimotor adaptation, led by TRISH. The project collects data before and after flight to understand sensorimotor abilities, change and recovery time to inform future missions to the moon.

TRISH, which is part of BCM’s Center for Space Medicine with partners Caltech and MIT, has launched experiments on numerous space missions to date, including Blue Origin's New Shepard rocket last November and Axiom Space's Ax-3 mission to the International Space Station last January.

Houston lab develops AI tool to improve neurodevelopmental diagnoses

developing news

One of the hardest parts of any medical condition is waiting for answers. Speeding up an accurate diagnosis can be a doctor’s greatest mercy to a family. A team at Baylor College of Medicine has created technology that may do exactly that.

Led by Dr. Ryan S. Dhindsa, assistant professor of pathology and immunology at Baylor and principal investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, the scientists have developed an artificial intelligence-based approach that will help doctors to identify genes tied to neurodevelopmental disorders. Their research was recently published the American Journal of Human Genetics.

According to its website, Dhindsa Lab uses “human genomics, human stem cell models, and computational biology to advance precision medicine.” The diagnoses that stem from the new computational tool could include specific types of autism spectrum disorder, epilepsy and developmental delay, disorders that often don’t come with a genetic diagnosis.

“Although researchers have made major strides identifying different genes associated with neurodevelopmental disorders, many patients with these conditions still do not receive a genetic diagnosis, indicating that there are many more genes waiting to be discovered,” Dhindsa said in a news release.

Typically, scientists must sequence the genes of many people with a diagnosis, as well as people not affected by the disorder, to find new genes associated with a particular disease or disorder. That takes time, money, and a little bit of luck. AI minimizes the need for all three, explains Dhindsa: “We used AI to find patterns among genes already linked to neurodevelopmental diseases and predict additional genes that might also be involved in these disorders.”

The models, made using patterns expressed at the single-cell level, are augmented with north of 300 additional biological features, including data on how intolerant genes are to mutations, whether they interact with other known disease-associated genes, and their functional roles in different biological pathways.

Dhindsa says that these models have exceptionally high predictive value.

“Top-ranked genes were up to two-fold or six-fold, depending on the mode of inheritance, more enriched for high-confidence neurodevelopmental disorder risk genes compared to genic intolerance metrics alone,” he said in the release. “Additionally, some top-ranking genes were 45 to 500 times more likely to be supported by the literature than lower-ranking genes.”

That means that the models may actually validate genes that haven’t yet been proven to be involved in neurodevelopmental conditions. Gene discovery done with the help of AI could possibly become the new normal for families seeking answers beyond umbrella terms like “autism spectrum disorder.”

“We hope that our models will accelerate gene discovery and patient diagnoses, and future studies will assess this possibility,” Dhindsa added.

Texas robotics co. begins new search for missing Malaysia Airlines flight 370

International News

Malaysia’s government has given final approval for a Texas-based marine robotics company to renew the search for Malaysia Airlines Flight 370, which is believed to have crashed in the southern Indian Ocean more than a decade ago.

Cabinet ministers agreed to terms and conditions for a “no-find, no-fee” contract with Texas-based Ocean Infinity to resume the seabed search operation at a new 5,800-square-mile site in the ocean, Transport Minister Anthony Loke said in a statement Wednesday. Ocean Infinity will be paid $70 million only if wreckage is discovered.

The Boeing 777 plane vanished from radar shortly after taking off on March 8, 2014, carrying 239 people, mostly Chinese nationals, on a flight from Malaysia’s capital, Kuala Lumpur, to Beijing. Satellite data showed the plane turned from its flight path and headed south to the far-southern Indian Ocean, where it is believed to have crashed.

An expensive multinational search failed to turn up any clues to its location, although debris washed ashore on the east African coast and Indian Ocean islands. A private search in 2018 by Ocean Infinity also found nothing.

The final approval for a new search came three months after Malaysia gave the nod in principle to plans for a fresh search.

Ocean Infinity CEO Oliver Punkett earlier this year reportedly said the company had improved its technology since 2018. He has said the firm is working with many experts to analyze data and had narrowed the search area to the most likely site.

Loke said his ministry will ink a contract with Ocean Infinity soon but didn’t provide details on the terms. The firm has reportedly sent a search vessel to the site and indicated that January-April is the best period for the search.

“The government is committed to continuing the search operation and providing closure for the families of the passengers of flight MH370,” he said in a statement.

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