This week's roundup of Houston innovators includes Grace Rodriguez of Impact Hub Houston, Youngro Lee of NextSeed, and Liz Youngblood of Baylor St. Luke's Medical Center. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — startup development, fintech, and health care — recently making headlines in Houston innovation.

Grace Rodriguez, CEO and executive director of Impact Hub Houston

Impact Hub Houston has two new initiatives for female founders. Photo courtesy of Impact Hub Houston

Two accelerator programs were recently announced and they both are aimed at supporting female founders — and one Houston organization is behind them both. Impact Hub Houston announced that it has partnered up with Frost Bank to sponsor eight female founders to participate in Impact Hub's new Accelerate Membership Program.

Additionally, Impact Hub Houston has teamed up with MassChallenge for their own initiative supporting female founders in the Houston-Galveston region in partnership with Houston-based Workforce Solutions. The three organizations are collaborating to launch launch a bootcamp to support female founders in the greater Houston region.

"As a female founder myself, I'm incredibly excited about this opportunity to support and uplift more women entrepreneurs and women-led businesses in our region," says Grace Rodriguez, CEO and executive director of Impact Hub Houston, in a news release. "By now, it's no secret that women, and especially women of color, are under-invested in; and this is our chance to change that by helping more women strengthen their businesses and prepare to seek funding." Click here to read more.

Youngro Lee, co-founder and CEO of NextSeed and COO of Republic

What does the future of investment look like? That's something Youngro Lee thinks about daily – and he shares his thoughts on this week's episode of the Houston Innovators Podcast. Photo courtesy of NextSeed

The world of investing is changing — and the power shift is tilting from the rich elite to individuals. Youngro Lee, co-founder and CEO of NextSeed and COO of Republic, has seen the change starting several years ago.

"Investing is traditionally seen as something you can't do unless you're rich," Lee says on this week's episode of the Houston Innovators Podcast. "There was a certain understanding of what anyone (looking to invest) should do. … But now the world is so different."

Lee shares more about the future of investing and how he's watched the Houston innovation ecosystem develop over the years on the episode. Click here to read more and stream the podcast.

Liz Youngblood, president of Baylor St. Luke's Medical Center and senior vice president and COO of St. Luke's Health

As we enter year two of the pandemic, the way hospitals function now and in the future is forever changed. Photo courtesy

No industry has been unaffected by COVID-19, Liz Youngblood, president of Baylor St. Luke's Medical Center and senior vice president and COO of St. Luke's Health, observes in a guest column for InnovationMap. But hospitals — they've had a spotlight shown on them and their technology adoption since day one of the pandemic.

"The pace of innovation for hospitals has been at breakneck speed — from the evolution of new treatment protocols to the need to reconfigure physical spaces to support an influx of patients while also promoting a healing environment during this unprecedented time," she writes.

Hospitals, she says, look and feel completely different now than they did last year and the year before that. Click here to read more.

As we enter year two of the pandemic, the way hospitals function now and in the future is forever changed. Photo via Getty Images

Houston expert: Hospitals are at the forefront of innovation due to pandemic

guest column

The COVID-19 pandemic has had a drastic effect on every industry throughout the world. Additionally, we have all experienced multiple changes to our daily routine such as schools implementing virtual and hybrid learning while reconfiguring classrooms to promote social distancing and fitness studios closing off every other cardio machine and bench.

But no industry has had to pivot and innovate more than health care, which has been ground zero for the pandemic.

The pace of innovation for hospitals has been at breakneck speed — from the evolution of new treatment protocols to the need to reconfigure physical spaces to support an influx of patients while also promoting a healing environment during this unprecedented time.

Hospitals look and feel a lot different today because of significant modifications that have been made to care for patients and limit exposure to the virus. While a number of these modifications occurred under temporary state waivers, some of these changes may be here to stay.

Adding windows and alternative communication options to every room

Hospitals found that every room is valuable during a pandemic. Identifying and converting any available space, including private rooms like offices, break rooms, and conference rooms, was essential to accommodate an influx of patients during a surge. And when dealing with a highly infectious area, it is imperative to maximize staff and physician efforts while also safely minimizing the amount of time that staff members enter and exit rooms.

One way to do this is by adding windows in doors to promote patient visibility. This increased visibility can improve patient safety while conserving critical personal protective equipment. However, a down side to limiting the amount of times staff members enter and exit rooms is reduced valuable communication opportunities, which is why alternative mechanisms to communicate with patients must be in place in addition to increased visibility.

Implementing additional negative pressure capabilities

Like adding windows to every patient door, negative pressure rooms exist to keep non-contaminated areas free of airborne pathogens. In a negative pressure room, the air in the room is pulled into a room instead of being pushed out of a room, which is very effective in preventing airborne contaminants from escaping the room and infecting other people. But hospitals are not traditionally built with significant numbers of negative pressure rooms as demand for these types of rooms has historically been low.

In addition, the traditional way to design a facility is to spread negative pressure rooms throughout the hospital instead of consolidating them onto specific units. Although not required for COVID-19 patients, negative pressure rooms are helpful in ensuring maximum capabilities within different zones. In instances where negative pressure rooms could not be created, HEPA filters can still be used to "scrub" the air.

Converting anesthesia machines to ventilators

Anesthesia machines are capable of providing life-sustaining mechanical ventilation to patients with respiratory failure from diseases like COVID-19. They are used for this purpose every day in the operating room. Although they are not recommended for long-term ventilator needs, anesthesia ventilators can be modified to provide ventilatory support and are an obvious first-line backup when there are not sufficient ICU ventilators to meet patient care needs.

Building barriers to increase the safety of care

Plexiglass barriers have become a common sight in daily life including the front desks at hospitals. However, hospitals have taken it a step further and have either built or sourced equipment such as intubation boxes, which can be used during the intubation process, which consists of placing a breathing tube into a patient's airway and then connecting it to a ventilator or anesthesia machine if the patient is having surgery. Intubations are often done by an anesthesiologist, intensive care or emergency room provider; however, traditionally we had not often dealt with highly-contagious patients, so providing a higher level of protection is an important step in the containment of this type of virus.

The way healthcare providers enter and exit a COVID patient's room is as important as the proper use of PPE. In a pre-pandemic world, hospitals didn't specifically create spaces or areas within patient floors for staff to remove and discard their PPE and there wasn't any visible signage warning them that they were about to enter or leave a high-risk area. Many hospitals across the country have implemented color-coded zones within their COVID floors to caution staff of the type of precautions they should be taking at any given time. The creation of zones helps to protect staff and reduce contamination opportunities within the unit itself. Red, yellow and green zones using visual markers can be created to help provide staff designated areas that certain processes must be followed such as where PPE must be worn, where it can be donned and doffed and where PPE should not be worn.

Managing complex logistical challenges

Hospitals have been challenged with having to continue to provide uninterrupted care for COVID and non-COVID patients during the pandemic, while also handling, storing and administering vaccines. Hospitals have been at the forefront of the vaccine distribution system, working closely with state and federal officials to distribute vaccines on a large scale and reach the underserved populations that were hit hardest by COVID-19. For example, Baylor St. Luke's chose Texas Southern University, located within the Third Ward of Houston, as a vaccine site to reach communities of color and leverage its accessible location and the school's pharmacy students and faculty. And more recently, the hospital worked with Rice University to administer vaccines at its football stadium, a large venue that can be accessed easily through public transportation. Having these offsite venues with ample space has helped alleviate the space burden on hospitals during the vaccination efforts. Non-traditional healthcare delivery locations like these allow health care providers to administer more doses, closer to targeted communities than would be possible at a single hospital.

As we enter year two of the pandemic, the way hospitals function now and in the future is forever changed. Hospitals continue to learn and adapt during the COVID-19 pandemic, and in case of another pandemic, hospitals are better equipped to quickly pivot to provide care for a surge of patients and to assist in the recovery efforts.

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Liz Youngblood is president of Baylor St. Luke's Medical Center and senior vice president and COO of St. Luke's Health.

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How Houston innovators played a role in the historic Artemis II splashdown

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Research from Rice University played a critical role in the safe return of U.S. astronauts aboard NASA’s Artemis II mission this month.

Rice mechanical engineer Tayfun E. Tezduyar and longtime collaborator Kenji Takizawa developed a key computational parachute fluid-structure interaction (FSI) analysis system that proved vital in NASA’s Orion capsule’s descent into the Pacific Ocean. The FSI system, originally developed in 2013 alongside NASA Johnson Space Center, was critical in Orion’s three-parachute design, which slowed the capsule as it returned to Earth, according to Rice.

The model helped ensure that the parachute design was large enough to slow the capsule for a safe landing while also being stable enough to prevent the capsule from oscillating as it descended.

“You cannot separate the aerodynamics from the structural dynamics,” Tezduyar said in a news release. “They influence each other continuously and even more so for large spacecraft parachutes, so the analysis must capture that interaction in a robustly coupled way.”

The end result was a final parachute system, refined through NASA drop tests and Rice’s computational FSI analysis, that eliminated fluctuations and produced a stable descent profile.

Apart from the dynamic challenges in design, modeling Orion’s parachutes also required solving complex equations that considered airflow and fabric deformation and accounted for features like ringsail canopy construction and aerodynamic interactions among multiple parachutes in a cluster.

“Essentially, my entire group was dedicated to that work, because I considered it a national priority,” Tezduyar added in the release. “Kenji and I were personally involved in every computer simulation. Some of the best graduate students and research associates I met in my career worked on the project, creating unique, first-of-its-kind parachute computer simulations, one after the other.”

Current Intuitive Machines engineer Mario Romero also worked on Orion during his time at NASA. From 2018 to 2021, Romero was a member of the Orion Crew Capsule Recovery Team, which focused on creating likely scenarios that crewmembers could encounter in Orion.

The team trained in NASA’s 6.2-million-gallon pool, using wave machines to replicate a range of sea conditions. They also simulated worst-case scenarios by cutting the lights, blasting high-powered fans and tipping a mock capsule to mimic distress situations. In some drills, mock crew members were treated as “injured,” requiring the team to practice safe, controlled egress procedures.

“It’s hard to find the appropriate descriptors that can fully encapsulate the feeling of getting to witness all the work we, and everyone else, did being put into action,” Romero tells InnovationMap. “I loved seeing the reactions of everyone, but especially of the Houston communities—that brought me a real sense of gratitude and joy.”

Intuitive Machines was also selected to support the Artemis II mission using its Space Data Network and ground station infrastructure. The company monitored radio signals sent from the Orion spacecraft and used Doppler measurements to help determine the spacecraft's precise position and speed.

Tim Crain, Chief Technology Officer at Intuitive Machines, wrote about the experience last week.

"I specialized in orbital mechanics and deep space navigation in graduate school,” Crain shared. “But seeing the theory behind tracking spacecraft come to life as they thread through planetary gravity fields on ultra-precise trajectories still seems like magic."

UH breakthrough moves superconductivity closer to real-world use

Energy Breakthrough

University of Houston researchers have set a new benchmark in the field of superconductivity.

Researchers from the UH physics department and the Texas Center for Superconductivity (TcSUH) have broken the transition temperature record for superconductivity at ambient pressure. The accomplishment could lead to more efficient ways to generate, transmit and store energy, which researchers believe could improve power grids, medical technologies and energy systems by enabling electricity to flow without resistance, according to a release from UH.

To break the record, UH researchers achieved a transition temperature 151 Kelvin, which is the highest ever recorded at ambient pressure since the discovery of superconductivity in 1911.

The transition temperature represents the point just before a material becomes superconducting, where electricity can flow through it without resistance. Scientists have been working for decades to push transition temperature closer to room temperature, which would make superconducting technologies more practical and affordable.

Currently, most superconductors must be cooled to extremely low temperatures, making them more expensive and difficult to operate.

UH physicists Ching-Wu Chu and Liangzi Deng published the research in the Proceedings of the National Academy of Sciences earlier this month. It was funded by Intellectual Ventures and the state of Texas via TcSUH and other foundations. Chu, founding director and chief scientist at TcSUH, previously made the breakthrough discovery that the material YBCO reaches superconductivity at minus 93 K in 1987. This helped begin a global competition to develop high-temperature superconductors.

“Transmitting electricity in the grid loses about 8% of the electricity,” Chu, who’s also a professor of physics at UH and the paper’s senior author, said in a news release. “If we conserve that energy, that’s billions of dollars of savings and it also saves us lots of effort and reduces environmental impacts.”

Chu and his team used a technique known as pressure quenching, which has been adapted from techniques used to create diamonds. With pressure quenching, researchers first apply intense pressure to the material to enhance its superconducting properties and raise its transition temperature.

Next, researchers are targeting ambient-pressure, room-temperature superconductivity of around 300 K. In a companion PNAS paper, Chu and Deng point to pressure quenching as a promising approach to help bridge the gap between current results and that goal.

“Room-temperature superconductivity has been seen as a ‘holy grail’ by scientists for over a century,” Rohit Prasankumar, director of superconductivity research at Intellectual Ventures, said in the release. “The UH team’s result shows that this goal is closer than ever before. However, the distance between the new record set in this study and room temperature is still about 140 C. Closing this gap will require concerted, intentional efforts by the broader scientific community, including materials scientists, chemists, and engineers, as well as physicists.”

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This article originally appeared on EnergyCapitalHTX.com.