A Houston entrepreneur has created a platform that puts artists first. Photo courtesy of PickleJar

Like so many business owners, Jeff James' inspiration for his innovative new music app PickleJar, came out of sheer necessity. Sitting in a bar in the buzzy Broadway district in Nashville, Tennessee, James, a serial entrepreneur, realized there had to be a better way to tip performing musicians.

"This young girl comes through the crowd carrying a Yeti bucket asking for 20 dollars for the band," James tells CultureMap. With no cash on hand, James donated via Square. "Sixty dollars later, I had so many questions: would she remember my name? Would she remember my songs? There's gotta be a better way to do this."

James, a former radio DJ and record label veteran, started scribbling his idea for a musician tipping app on a napkin. Two years later, PickleJar was sparked, James says, because "every musician we spoke to hates the way they're paid on these apps like Venmo and Facebook."

Pushing an "artist first," mission statement, PickleJar ensures that every musician utilizing the app keeps 100 percent of the money — something unheard of when James started the process two years ago. Fans donate to musicians on the app, and in turn, get five times that tip in proprietary digital currency called Pick Coins.

"If you tip 100 dollars to a musician, you get 500 Pick Coins," explains James, "that goes to buying tickets, merch, or VIP experiences on our app." Another artist-first perk: The artist also gets 500 Pick Coins in that scenario.

With its own e-commerce platform, PickleJar allows fans to use these Pick Coins for experiences, and musicians to use them for much-needed equipment. PickleJar has partnered with Austin-based Strait Music Company, which will provide musicians with instruments and gear. Musicians can create their own wish lists so that fans can directly contribute to the desired gear.

Fittingly, the company has partnered with local venues for themed nights. Buzzy bar McIntyre's Downtown will feature a tip-worthy Texas artist every Wednesday night in its PickLounge.

PickleJar also allows musicians to livestream. "On Facebook Live, data shows that only about eight to 10 percent of an artist's audience know they're live. On top of that, Facebook takes 30 to 40 percent of the tips." With PickleJar, 100 percent of an artists fans will be notified when the artists in livestreaming.

Fans can even donate directly to a musician's nonprofit of choice, something happening now during Hurricane Ida relief efforts. Numerous artists on PickleJar are raising funds for Ida assistance, James notes. "We really believe that a 'gratitude economy' is emerging," he says. "We wanted to create the easiest way possible for fans to say thank you."

That thank-you option also means fans can send direct messages, notes, and even pictures on the app, which, James acknowledges with a chuckle, could get very interesting.

Another musician-first nuance not found on other apps: PickleJar allows for "smart" splits, so that musicians are appropriately compensated for their specific contribution. An artist who wrote songs and drove the van to a gig, for example, can be funneled a higher percentage of tips than bandmates who contributed less.

James and his Houston-based tech team are also working on a TV channel on streaming devices, dubbed PickleJar Plus.

While one might be tempted to assume PickleJar is meant for those gig-to-gig, struggling musicians, James assures that the app is meant for every level, which he breaks down accordingly:

  • "Never-evers": These folks will never get signed, but use the app to get better
  • "Got talent, not signed": Artists can use PickleJar to build audiences and crowdfund
  • "I'm signed/labeled": Here, signed artists curate setlists which can be monetized via tips
  • "Idols": These artists are already brands. "Kenny Chesney can use this to make sure every dollar goes to a nonprofit," says James. Chesney's team can watch a meter, and when donations hit a specific dollar amount, Chesney can reward fans with their favorite song."

If all this seems to point to James one day managing and representing artists, James says that idea is not entirely off. PickleJar could one day be the world's biggest independent record label, he acknowledges, by the way it allows indies to promote themselves.

"We were in a meeting and the guy says, 'you're gonna change the entertainment world forever,'" James, recalls. "We hope so. We just want to build a relationship with artists — and put them first."

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This article originally ran on CultureMap.

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Houston biotech co. raises $11M to advance ALS drug development

drug money

Houston-based clinical-stage biotechnology company Coya Therapeutics (NASDAQ: COYA) has raised $11.1 million in a private investment round.

India-based pharmaceuticals company Dr. Reddy’s Laboratories Inc. led the round with a $10 million investment, according to a news release. New York-based investment firm Greenlight Capital, Coya’s largest institutional shareholder, contributed $1.1 million.

The funding was raised through a definitive securities purchase agreement for the purchase and sale of more than 2.5 million shares of Coya's common stock in a private placement at $4.40 per share.

Coya reports that it plans to use the proceeds to scale up manufacturing of low-dose interleukin-2 (IL-2), which is a component of its COYA 302 and will support the commercial readiness of the drug. COYA 302 enhances anti-inflammatory T cell function and suppresses harmful immune activity for treatment of Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s disease and Alzheimer’s disease.

The company received FDA acceptance for its investigational new drug application for COYA 302 for treating ALS and FTD this summer. Its ALSTARS Phase 2 clinical trial for ALS treatment launched this fall in the U.S. and Canada and has begun enrolling and dosing patients. Coya CEO Arun Swaminathan said in a letter to investors that the company also plans to advance its clinical programs for the drug for FTD therapy in 2026.

Coya was founded in 2021. The company merged with Nicoya Health Inc. in 2020 and raised $10 million in its series A the same year. It closed its IPO in January 2023 for more than $15 million. Its therapeutics uses innovative work from Houston Methodist's Dr. Stanley H. Appel.

New accelerator for AI startups to launch at Houston's Ion this spring

The Collectiv Foundation and Rice University have established a sports, health and wellness startup accelerator at the Ion District’s Collectiv, a sports-focused venture capital platform.

The AI Native Dual-Use Sports, Health & Wellness Accelerator, scheduled to formally launch in March, will back early-stage startups developing AI for the sports, health and wellness markets. Accelerator participants will gain access to a host of opportunities with:

  • Mentors
  • Advisers
  • Pro sports teams and leagues
  • University athletics programs
  • Health care systems
  • Corporate partners
  • VC firms
  • Pilot projects
  • University-based entrepreneurship and business initiatives

Accelerator participants will focus on sports tech verticals inlcuding performance and health, fan experience and media platforms, data and analytics, and infrastructure.

“Houston is quickly becoming one of the most important innovation hubs at the intersection of sports, health, and AI,” Ashley DeWalt, co-founder and managing partner of The Collectiv and founder of The Collectiv Foundation, said in a news release.

“By launching this platform with Rice University in the Ion District,” he added, “we are building a category-defining acceleration engine that gives founders access to world-class research, global sports properties, hospital systems, and venture capital. This is about turning sports-validated technology into globally scalable companies at a moment when the world’s attention is converging on Houston ahead of the 2026 World Cup.”

The Collectiv accelerator will draw on expertise from organizations such as the Rice-Houston Methodist Center for Human Performance, Rice Brain Institute, Rice Gateway Project and the Texas Medical Center.

“The combination of Rice University’s research leadership, Houston’s unmatched health ecosystem, and The Collectiv’s operator-driven investment platform creates a powerful acceleration engine,” Blair Garrou, co-founder and managing partner of the Mercury Fund VC firm and a senior adviser for The Collectiv, added in the release.

Additional details on programming, partners and application timelines are expected to be announced in the coming weeks.

4 Houston-area schools excel with best online degree programs in U.S.

Top of the Class

Four Houston-area universities have earned well-deserved recognition in U.S. News & World Report's just-released rankings of the Best Online Programs for 2026.

The annual rankings offer insight into the best American universities for students seeking a flexible and affordable way to attain a higher education. In the 2026 edition, U.S. News analyzed nearly 1,850 online programs for bachelor's degrees and seven master's degree disciplines: MBA, business (non-MBA), criminal justice, education, engineering, information technology, and nursing.

Many of these local schools are also high achievers in U.S. News' separate rankings of the best grad schools.

Rice University tied with Texas A&M University in College Station for the No. 3 best online master's in information technology program in the U.S., and its online MBA program ranked No. 21 nationally.

The online master's in nursing program at The University of Texas Medical Branch in Galveston was the highest performing master's nursing degree in Texas, and it ranked No. 19 nationally.

Three different programs at The University of Houston were ranked among the top 100 nationwide:
  • No. 18 – Best online master's in education
  • No. 59 – Best online master's in business (non-MBA)
  • No. 89 – Best online bachelor's program
The University of Houston's Clear Lake campus ranked No. 65 nationally for its online master's in education program.

"Online education continues to be a vital path for professionals, parents, and service members seeking to advance their careers and broaden their knowledge with necessary flexibility," said U.S. News education managing editor LaMont Jones in a press release. "The 2026 Best Online Programs rankings are an essential tool for prospective students, providing rigorous, independent analysis to help them choose a high-quality program that aligns with their personal and professional goals."

A little farther outside Houston, two more universities – Sam Houston State University in Huntsville and Texas A&M University in College Station – stood out for their online degree programs.

Sam Houston State University

  • No. 5 – Best online master's in criminal justice
  • No. 30 – Best online master's in information technology
  • No. 36 – Best online master's in education
  • No. 77 – Best online bachelor's program
  • No. 96 – Best online master's in business (non-MBA)
Texas A&M University
  • No. 3 – Best online master's in information technology (tied with Rice)
  • No. 3 – Best online master's in business (non-MBA)
  • No. 8 – Best online master's in education
  • No. 9 – Best online master's in engineering
  • No. 11 – Best online bachelor's program
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This article originally appeared on CultureMap.com.