Lindsey Rose King created a seasonal home goods box that shows consumers how to enjoy each item. Courtesy of Mostess

A few years ago, Lindsey Rose King offered to host her friend's engagement party, and she realized she had no clue where to start. There weren't any real resources out there for her to seek out.

King created Mostess, a seasonally curated home goods subscription box aiming to make it easier to host friends and family into their homes. The company was founded in January of 2017.

"I came up with the idea out of a need," says King, founder and lead curator, "it's hard to casually invite people into your house."

Almost two years later, King has managed to accomplish a lot of her goals, and Mostess has a great retention rate of subscribers with about a 30 percent growth each quarter, King says.

"We have a 5 percent churn rate, so 95 percent of customers have been customers since their first purchase," says King.

Mostess moves to disrupt the retail space by changing how consumers shop for home goods, accessories, and tabletop items. The box presents products in a different setting than consumers are used to seeing in a brick-and-mortar store by combining products from different brands and lines that may not be typically paired.

"Consumers are getting a product because we are referring it and picking it for them," King says. "We're choosing for the consumer, rather than them choosing themselves."

Growing business
In need of more space, the growing company recently moved into a warehouse in the Houston-area in a partnership with Alpha Graphics West Houston to launch its first local fulfillment center.

Currently, Mostess ships to 48 states, and next year, King says she wants to be able to ship to Alaska and Hawaii by July. Since the box has already got some buzz around it in Canada, King says she hope to be able to start her first international shipping there by 2020.

Mostess is in the wrapping up its busiest season; the company just released its winter box, which, along with the autumn box, King says subscribers usually purchase additional boxes for friends and family.

Looking forward to 2019, she's got exciting advancements for her subscribers.

In 2019, Mostess will begin offering slight customizations to each seasonal box and a special evergreen box. Customers will be able to purchase add-on items beginning with the spring box, such as extra candles or accessories in addition to what is offered. The Mostess evergreen boxes will have neutral and classic home accessories and hosting pieces. King says she wants these boxes to be a go-to gift idea or party-hosting asset for everything from a housewarming to an engagement party.

Starting from scratch
King first had the idea for Mostess toward the end of her 10-year stint living in Washington, D.C. Anticipating a move to Houston, King began to research local bloggers and small businesses to build a support system and platform for Mostess prior to the launch.

"In the small business world in Houston, there is the blogging community and there are actual small businesses," says King. "Both are very active and both very open to chatting about how to make business work between both of you."

King tells InnovationMap that Houston is an ideal city for an entrepreneur, offering a collaborative community of friendly, laid back, and hard-working small business owners.

King shares that she launched Mostess without any outside investment, using only her personal funds to get the product off the ground and relied on her friends and family as a test market. From there, she sought feedback from every single customer and potential customer, collected data, and tweaked details leading up to the launch.

"There was not a home goods subscription box on the market," says King, "I didn't have something to model after."

Elegant items shipped to your door

Paige Baker/Mostess

Mostess memberships begin at $120 per seasonal box.

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UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.

New Texas Stock Exchange officially begins trading in Dallas

Welcome to Y'all Street

Two-step aside, New York Stock Exchange and Nasdaq. The Dallas-based Texas Stock Exchange, nicknamed Y’all Street, just kicked off live trading with five stocks — and lots of Lone Star ambition.

“The Texas Stock Exchange aims to revitalize competition for [stock] issuers, establish the premier venue for listings, and create a world-class trading platform for all market participants,” the exchange says in a fact sheet.

The exchange — whose Texas-influenced nickname is a nod to New York City’s Wall Street — has collected at least $275 million in investments. The roughly 90 financial backers of TXSE include Bank of America, BlackRock, Charles Schwab, Citadel Securities, Dell Family Office, Fortress, Goldman Sachs, and JPMorgan Chase.

Representatives of TXSE couldn’t be reached for comment. On its website, the exchange calls itself “the most well-capitalized equities exchange to ever be approved” by the U.S. Securities and Exchange Commission (SEC).

Not to be outdone, NYSE has launched Dallas-based NYSE Texas and Nasdaq has expanded its presence in Dallas.

Y’all Street adds to Dallas-Fort Worth’s rising status as a major hub for financial services, with The Wall Street Journal naming North Texas the country’s second biggest financial hub after New York City.

“A homegrown national exchange means more jobs, more investment, and more growth opportunities for businesses and communities across the Lone Star State,” Gabriela von zur Muehlen, senior vice president and chief policy officer at the Texas Association of Business, told The Texas Tribune.

Bulent Temel, an associate professor of practice in economics at the University of Texas at San Antonio, told Texas Standard that TXSE “is going to boost the credibility of the Texas economy.”

Texas’ estimated gross domestic product (GDP), a yardstick for the size of an economy, climbed to a record-setting $2.9 trillion in 2025, making it the state with the second highest GDP after California. DFW’s estimated GDP in 2023 stood at $744.6 billion, eclipsing the GDP of many countries.

“The center of gravity for American capitalism is now headquartered in the Boom Belt,” Abbott proclaimed in April, referring to an 11-state region (including Texas) in the South and Southeast that’s seeing tremendous economic and population growth. “The Texas Stock Exchange is the natural extension of that capitalism. It ensures that capital markets will reflect the quadrant that is driving American growth.”

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This article originally appeared on CultureMap.com.

Orion vehicle manager reflects on Artemis II, looks to 2028 moon mission

Q&A

Humanity is finally headed back to the moon after more than half a century. This year's launch of the Artemis II mission in the Orion spacecraft put four crew members in lunar orbit and tested the new ship developed by Lockheed Martin.

Everything went smoothly, safely returning astronauts home, but there is always room to improve. InnovationMap chatted via email with Orion vehicle manager Branelle Rodriguez, shortly after a talk at The Ion, for insight on how Orion might perform in the future as the next lunar landing approaches in early 2028.

InnovationMap: How satisfied are you with the way Orion operated on this past mission?

Branelle Rodriguez: Orion performed exceptionally well during Artemis II, successfully demonstrating critical spacecraft capabilities, including life support systems, displays and controls, and executing manual piloting operations. Artemis II brought humans back to the moon, achieving key exploration and scientific imagery, while validating systems essential for future Artemis missions.

IM: What is the most important thing you learned about improving Orion for the next mission?

BR: The Artemis II mission provided invaluable insights into crew operations and spacecraft performance in a deep-space environment. With every mission, NASA applies lessons learned to continuously improve Orion’s operations, validate design and ensure mission readiness. Artemis II offered our first opportunity to evaluate several new systems and gain a deeper understanding of what it is like for astronauts to live and work inside the spacecraft. The operational, technical and human factors data collected are being integrated across the program to refine future missions, reduce risk and enhance overall mission success.

IM: How has Orion helped the mission to explore space?

BR: Orion is one of NASA’s foundational elements for human deep space exploration—not only supporting the mission but serving as a core component of it. It is currently the only spacecraft capable of carrying crew on deep space missions and returning them safely to Earth from the high speeds required from the vicinity of the moon. No other spacecraft has the technology to endure the extremes that come with human deep-space travel, such as advanced environmental and life support, navigation, communications, radiation shielding, and the world’s largest ablative heat shield to protect the astronauts during reentry into Earth’s atmosphere. Orion has already taken astronauts to explore space farther than ever before—252,756 miles from Earth— and will carry crews to the moon on future missions to explore the lunar South Pole region. The astronauts’ observations, samples, and data collected on these future missions will expand our understanding of our solar system and home planet.

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This conversation has been edited for brevity and clarity.