While everyone always looks to Silicon Valley as the model of the ideal startup ecosystem, Houston is forging its own path. Getty Images

As WeWork's fall from grace continues to dominate the headlines and we monitor the slew of layoffs and dipping share prices afflicting this year's Silicon Valley darlings, we reflect on Houston's own startup ecosystem. How are Houston startups and investors similar to and different from Silicon Valley early-stage deals? What are the drivers and factors that may be unique to Houston and how do they influence outcomes?

Jamie Jones, executive director of Lilie, sat down with early stage investor and Rice Business alum, Dougal Cameron of Golden Section Technology Venture Capital (GSTVC), to discuss the Houston startup and funding ecosystem. From that discussion, a number of key features emerged:

From Cameron's experience, Houston investors have historically focused on unit economics and profitability, in addition to top line growth, as their key performance measures. As an enterprise software investor, he notes that an indicator of a healthy venture that warrants early stage investment is one where profitability can be achieved as the venture reaches the $1 million revenue mark. Cameron, like other early stage investors in Houston, are interested in ventures that produce sustainable growth not only growth for growth's sake.

While early stage investment capital in Houston does flow, it does not do so at the same check sizes and the same velocity that you may see in Silicon Valley. Analysis of Pitchbook data indicates that Houston firms raised $28.1M in seed and early-stage funding in Q3 2019 versus $2.86B for Silicon Valley based ventures. The belief is that the density of the capital network in Silicon Valley means that if you get one $500,000 check then you will very likely to get others. Cameron noted that he believes the effects of loss aversion are on full display — no firm wants to be the one that passes on the next Google.

However, in Houston, entrepreneurs must be scrappy to pull together funding and ensuring they hit milestones along the way in order to drive scarcer investment into their ventures. From Cameron's perspective, Houston entrepreneurs own their cash balance and strive to keep their overhead low by working out of cheaper spaces, leveraging friends and family to contribute to the venture in its early days, etc.

With fewer investment dollars flowing in Houston, the use of Simple Agreements for Future Equity (SAFEs), which are common in Silicon Valley, are rarely used in Houston. Why? Cameron believes that using unpriced and loosely binding agreements may work in an ecosystem where startups are pushed for rapid top-line growth and may be burning through tens-of-thousands of dollars per month and will need to raise capital quickly, which will drive a pricing event. However, in Houston, investors may prefer arrangements that provide some downside risk.

Examples include convertible notes that include a lien on assets, which would be virtually unheard of in Silicon Valley, or through priced fundraising rounds. Without broad and deep capital networks and the pressure of rapid top-line growth, near term pricing events are not guaranteed, pushing Houston investors to prefer other deal structures.

While everyone agrees that Houston and the robust startup ecosystem that is growing across the city needs more cash to catalyze growth, Cameron firmly believes that new capital coming into the city must be the right type of capital. Capital that will not negatively distort the ecosystem by driving early-stage entrepreneurs to strive for top-line growth that is not sustainable through a profitable business model. This type of capital will not offer exorbitantly-sized seed rounds removing the entrepreneur's need to be scrappy and cost conscious.

We must understand that many Houston entrepreneurs seek to build businesses that have lasting impact and are not only "growing to close," the model Silicon Valley seems to have embraced over the past 7 to 10 years. Cameron is nervous that first big checks that come from outside Houston will push unprofitable businesses forward and will sour the market for local investors that are starting to engage in startup-investing.

While everyone always looks to Silicon Valley as the model of the ideal startup ecosystem, Houston may offer a look into the model of the future — one that is focused on building durable, profitable businesses by right-sizing growth over the venture's life-cycle. For Houston-based entrepreneurs, this means the opportunity to access capital that emphasizes sustainable, smart growth.

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Jamie Jones, executive director of the Liu Idea Lab for Innovation & Entrepreneurship at Rice University, and Dougal Cameron, managing director of Gold Section Technology Ventures and 2013 Rice Business alum, wrote this article for LILIE.

This article originally appeared on Liu Idea Lab for Innovation & Entrepreneurship's blog.

Check out these panels, networking meetups, and more. Getty Images

10+ can't-miss Houston business and innovation events for February

Where to be

Despite the short month, Houston will play host to tons of innovation networking, panel, and meetup events throughout the month of February. And, it's a leap year, so take that as an opportunity to jump into the startup ecosystim in town.

If you know of innovation-focused events for this month or next, email me at natalie@innovationmap.com with the details and subscribe to our daily newsletter that sends fresh stories straight to your inboxes every morning.

February 4 — How AI Can Boost Your Business with Ryan Shirzadi of Tekrevol

How can artificial intelligence help grow your business? Specifically, Ryan Shirzadi of Tekrevol will be covering the social impacts, industries affected, why you need an AI strategy, and how AI can help small businesses grow. Networking will follow the discussion and pizza will be provided by Tekrevol.

Details: The event is from 6 to 7:30 pm on Tuesday, February 4, at Station Houston (1301 Fannin Street, Suite 2440). Learn more.

February 5 — Meet and Greet with Pat Matthews, CEO & Founder of Active Capital

Meet Active Capital's founder and CEO, Pat Matthews. Rakesh Agrawal, founder and CEO of Snapstream, will interview Matthews followed up by an open Q&A and conversation with the audience.

Details: The event is from 5:30 to 6:45 pm on Wednesday, February 5, at WeWork (708 Main Street, 3rd Floor). Learn more.

February 5 — Houston Social Entrepreneurship Meetup

The meetup brings together like-minded individuals from the nonprofit, social enterprise, impact investing, technology and many other fields to understand the concept of social entrepreneurship and be inspired to find new ways to tackle local social issues. At each meetup, you'll get an intro to social entrepreneurship, hear from a social entrepreneur in Houston, and network with other changemakers from across the entrepreneur ecosystem.

Details: The event is from 5:30 to 7:30 pm on Wednesday, February 5, at Impact Hub Houston @ The Cannon Downtown (1801 Main St., 13th Floor). Learn more.

February 6 — Fail Forward presented by Frost Bank

Join BakerRipley and Frost Bank for an evening of #FailForward fun and get real, behind-the-scenes stories straight from entrepreneurs on the challenges they faced trying to access and raise funding for their small business or startups.

Details: The event is from 6 to 8 pm on Thursday, February 6, at BakerRipley Center (4450 Harrisburg Blvd.). Learn more.

February 12 — The Impact of AI on Automation and the Future of the Workforce

Technology and innovation are rapidly changing how we do and think about work. This panel event seeks to bring together respected leaders in the corporate and entrepreneurial worlds to have meaningful conversations on AI, automation and the future of workforce.

Details: The event is from 6:30 to 9 pm on Wednesday, February 12, at GA Houston (1301 Fannin St, Floor 21). Learn more.

February 13 — Female Founders Breakfast with Baker Botts and The Artemis Fund

Baker Botts L.L.P. and The Artemis Fund have come together to bring you a breakfast panel discussion on how a good corporate governance system and a little corporate housekeeping can avoid larger messes down the road.

Details: The event is from 8:30 to 10:30 am on Thursday, February 13, at Baker Botts (910 Louisiana St., 32nd Floor). Learn more.

February 18 — How She Got There: Women Leaders in Tech

Join General Assembly for an evening good conversation with a panel of females in tech. These inspirational women will share their stories on how they got to where they are today and share their insights into being a woman in business and tech.

Details: The event is from 6:30 to 9 pm on Tuesday, February 18, at GA Houston (1301 Fannin St, Floor 21). Learn more.

February 19 — Houston Angel Summit

Join the Houston Angel Network for its bi-annual summit. Attendees will learn the basics of angel investing as well as hear from experts on the topics of term sheets and tax implication of early stage investing. This event is open to accredited investors, HAN members and individuals from our partnership organizations. The price of attendance — $100 — will be applied to annual membership if attendees decide to join the Houston Angel Network.

Details: The event is from 9 am to 3 pm on Wednesday, February 19, at Liu Idea Lab for Innovation and Entrepreneurship (Cambridge Building at Rice University). Learn more.

February 20 — The Five W's of Holding Your First, First-in-Human Trial

Who, what, when, where and why to hold your first, first-in-human clinical trial? JLABS has tapped into experts in the field from Johnson & Johnson, CROs and agencies to help you answer these questions and more.

Details: The event is from 11:30 am to 2 pm on Thursday, February 20, at JLABS @ TMC (2450 Holcombe Blvd.). Learn more.

February 20 — Bunker Brews Houston: How to be Mentored in Your Business

Lots of entrepreneurs fail to seek out mentors, and struggle in silence and isolation because of it. Some will find great mentors, but fail to recognize the unspoken rules of the road to acquire, activate, and maintain a mentor-mentee relationship. Hear from some great local mentors of business owners.

Details: The event is from 6 to 8 pm on Thursday, February 20, at MassChallenge (1313 Main St., Suite 210). Learn more.

February 20 — Rising Stars in Houston Health Tech

Join General Assembly for an epic night with some of the Houston's most inspiring healthtech founders and leaders. In a candid discussion, they'll share their stories and insights.

Details: The event is from 6:30 to 9 pm on Thursday, February 20, at GA Houston (1301 Fannin St, Floor 21). Learn more.

February 24 — Made in Houston: Celebrating Black History Month

In honor of Black History Month, General Assembly has organized an evening with some of Houston's legendary innovators and creators. Each speaker will share their tips and tricks on how to create a unique product, service or brand that's pushing the boundaries while sharing their journey.

Details: The event is from 6:30 to 9 pm on Monday, February 24, at GA Houston (1301 Fannin St, Floor 21). Learn more.

February 25 — The Cannon Lunch & Learn: Show me the Money

As an early stage company, raising capital is or will be a significant part of your efforts and can present major challenges. Preparation and an understanding of what drives value is crucial to attracting investors. Join Cannon partner, Baker Tilly, as they provide an overview of the capital raise process and highlight key factors to consider when preparing to raise capital.

Details: The event is from 11:30 am to 1 pm on Tuesday, February 25, at The Cannon (1334 Brittmoore Road). Learn more.

Here's your one-stop shop for innovation events in Houston in September. Getty Images

10+ can't-miss Houston business and innovation events for September

Where to be

The busy fall event season is kicking off this month with tons of Houston innovation pitch events, educational panels, and networking opportunities.

If you know of innovation-focused events for this month or next, email me at natalie@innovationmap.com with the details and subscribe to our daily newsletter that sends fresh stories straight to your inboxes every morning.


September 5 — MassChallenge Texas in Houston Finale and Startup Showcase

The top startups from the inaugural MassChallenge Texas cohort in Houston will be recognized by community leaders to a room full of potential investors and customers, MassChallenge mentors, VIP community leaders, and their loved ones.

Details: The event is from 6 to 8 pm on Thursday, September 5, at House of Blues Houston (1204 Caroline St.). Learn more.

September 5 — Frost Bank: Fail Forward Series

Join Impact Hub Houston for an evening of #FailForward — behind-the-scenes stories straight from entrepreneurs on the challenges they faced trying to access and raise funding for their small business or startups. And, learn from bankers and financial experts what those entrepreneurs could have done to make their journey easier and more successful.

Details: The event is from 6 to 8 pm on Thursday, September 5, at BakerRipley Leonel Castillo Community Center (2101 South Street). Learn more.

September 6 — Finding your Product-Market fit via the W3 method

Amos Schwartzfarb, Author of Sell More Faster - The Ultimate Sales Playbook for Startups and Managing Director of Techstars Austin will deliver a hands-on workshop for founders (seed through Series A) that will enable you to identify the path to achieving product-market fit. Included in the $25 workshop is a signed copy of Sell More Faster.

Details: The event is from 11 am to 12:30 pm on Friday, September 6, at WeWork Labs (708 Main St., 3rd floor). Learn more.

September 10 — Founder Institute's inaugural cohort graduation showcase

The fresh (and first) graduates of the Founder Institute in Houston are celebrating the completion of their program. The graduation celebration will consist of a leadership focused commencement speech, hearing from the graduates (remarks and pitch), and showcase where each company will have a display table and be able to be speak one-on-one.

Details: The event is from 6 to 9 pm on Tuesday, September 10, at Station Houston (1301 Fannin Street, #2440). Learn more.

September 11 — Energy and Clean Technology Venture Forum XVII

The Rice Alliance's Energy and Clean Technology Venture Forum is the largest energy and clean technology venture capital conference in the U.S. open, to all emerging energy technology companies (both traditional energy and alternative energy).

Details: The event is from 8:30 am to 5 pm on Wednesday, September 11, at Jones Graduate School of Business (Rice University, 1900 Rice Blvd.). Learn more.

September 12 — HX Capital Summit 2019: Presented by JPMorgan Chase

Join Houston Exponential for its 2nd Annual Capital Summit, which will focus on the latest activity amongst Houston investments. This one-day event will highlight panel discussions from all aspects of Houston's innovation scene.

Details: The event is from 7:30 am to 3 pm on Thursday, September 12, at the Shell Auditorium (Rice University). Learn more.

September 12 — Cooley x JLABS @ TMC: Medtech Startup Fundamentals

Join Cooley, JLABS, and TMC Innovation for a half-day seminar gathering leading executives, investors, entrepreneurs, and thought leaders in the medical technology industry. Speakers will explore market trends and share strategies on how to position your startup for growth and success.

Details: The event is from 12:30 to 5:30 pm on Thursday, September 12, at the JLABS @ TMC (2450 Holcombe Blvd). Learn more.

September 17 — Raising Capital with Investment Crowdfunding

Station Houston, NextSeed, and the Greater Houston Black Chamber of Commerce are putting on a discussion about fundraising online.

Details: The event is from 11:30 am to 1:30 pm on Tuesday, September 17, at Station Houston (1301 Fannin Street, #2440). Learn more.

September 19 — The Cannon Grand Opening

The Cannon, an entrepreneurial hub in West Houston, is celebrating its new digs. Join the party to learn about coworking at The Cannon, to network with Houston's innovation ecosystem, and more.

Details: The event is from 4 to 9 pm on Thursday, September 19, at The Cannon (1336 Brittmoore Road). Invite only.

September 19 — JLABS x UH: Startup Pains: From Academia to Startup

JLABS and the University of Houston Technology Bridge present a special installment of the university's monthly Startup Pains. This month the focus is on licensing and technology transfer.

Details: The event is from 5:30 to 7 pm on Thursday, September 19, at the JLABS @ TMC (2450 Holcombe Blvd). Learn more.

September 24 — The Future of Payments: How Fintech, Crypto, and Blockchain are Transforming E-Commerce

The global economy is powered by 125 million business and payments between those businesses transacted over a variety of technologies. In the US, $2 trillion of the $58 trillion in payments generated by small business are "other" — new digital payment technologies including cryptocurrency and blockchain created by fintechs, banks and large players like Facebook and JP Morgan. Over time, the remaining $56 trillion will shift from paper checks to more digital forms. A change in the payments landscape is imminent, and in many ways, the US is behind in digital acceptance. What will this change look like? Join Vinay Pai, senior vice president of engineering at Bill.com, as he discusses.

Details: The event is from 4 to 5 pm on Tuesday, September 24, at Duncan Hall (Rice University). Learn more.

September 24 — The Eco-System of the Language Industry: Panel and Networking Event

Introducing the first Women in Localization Texas Chapter Houston Event. Winnie Heh, associate chapter manger - mentoring for the Silicon Valley Chapter, and Middlebury Institute of International Studies Career Advisor, Translation, Interpretation & Localization Management, will be presenting on importance of localization and various localization job functions available in our rapidly globalized world.

Details: The event is from 6 to 8 pm on Tuesday, September 24, at Station Houston (1301 Fannin Street, #2440). Learn more.

September 24 & 25 — Innovation Engineering Quick Start Class

Bruce G. Hall, CEO and president of eureka! inventing is teaching an abridged version of his innovation engineering course that's offered at the University of Houston. InnovationMap readers can get half off by registering through this link.

Details: The course is on either Tuesday, September 24, or Wednesday, September 25, at Energy Corridor Marriott (16011 Katy Fwy).Learn more.

September 25 — Third Coast Innovators Mixer

Calling all innovators and entrepreneurs in the Third Coast. JLABS @ TMC is hosting a networking event with fellow innovators and entrepreneurs in the ecosystem as well as current JLABS residents and the JLABS @ TMC team.

Details: The event is from 5 to 7 pm on Wednesday, September 25, at the JLABS @ TMC (2450 Holcombe Blvd). Learn more.

September 25 — Energy Tech Night

Energy Tech Night offers insights from energy digitalization/innovation/emerging tech experts and rapid-fire pitches from the cutting edge in startups offering solutions for the energy challenges of today & tomorrow.

Details: The event is from 6:30 to 8:30 pm on Wednesday, September 25, at Saint Arnold Brewery (2000 Lyons Ave) Learn More

Life Time Work opening its first Houston location is among this roundup of Houston innovation news. Courtesy of Life Time Work

Hypergiant receives funding from Japan, UH honored for entrepreneur program, coworking space opens, and more Houston innovation news

Short stories

In the Houston innovation news cycle, it's hard to keep up. Three higher education institutions are celebrating big wins within innovation and entrepreneurialism, a new coworking space joins the scene, and a health tech competition launches out of the Texas Medical Center.

Here are all the short stories within Houston innovation that you may have missed.

Texas AI company makes international partnership

Photo via hypergiant.com

Hypergiant Industries, a Texas industrial AI company with a presence in Houston, announced that it has received funding from and has entered into a partnership with Japan-based Sumitomo Corporation of Americas. The relationship will allow the company to enable and accelerate Hypergiant's AI-driven innovation initiatives across over 900 Sumitomo subsidiaries and associated companies.

"We're proud to be backed by a global leader like SCOA," says Ben Lamm, CEO and co-founder of Hypergiant, in a release. "SCOA is a company that has advanced so many industries with critical technological breakthroughs decade after decade. This relationship will ensure that both SCOA and Hypergiant remain ahead of the competition in AI for years to come."

The funding amount wasn't disclosed.

Bauer College of Business gets top marks

Photo via bauerticker.uh.edu

The Deshpande Foundation has selected The University of Houston for its 2019 Entrepreneurial University Award, recognizing the Cyvia and Melvyn Wolff Center for Entrepreneurship at the C.T. Bauer College of Business.

"Over the past decade, the Wolff Center's reputation as one of the nation's leading entrepreneurship programs has grown tremendously, and this award from the Deshpande Foundation reinforces that Bauer College is empowering students to innovate through a world-class program that emphasizes experiential learning and personalized attention by dedicated mentors," says Paul A. Pavlou, incoming dean of the Bauer College, in a release.

The award was announced by the Massachusetts-based organization at the Deshpande Symposium for Innovation and Entrepreneurship in Higher Education at the University of Massachusetts Lowell on June 11.

Life Time Work opens its doors

Courtesy of Life Time Work

Life Time Work's first Houston-area location has opened its doors in City Centre Five at 825 Town & Country Lane. The next location has already been announced to open in downtown Houston next year.

"Life Time Work is a natural extension of the lifestyle brand we have built in our athletic resorts over the past 27 years," says Life Time Work president, James O'Reilly, in a release. "With Houston's continued growth and diversified business and entrepreneurial community, City Centre is the perfect location for us to unveil this concept. We look forward to helping our members in their pursuit of a fulfilling and healthy work life."

The 25,000-square-foot space features 79 desks, 48 offices, lounge spaces, eight phone booths, two phone rooms, five conference rooms, and more features.

JLABS @ TMC opens contest for health care startups

Photo via jlabs.jnjinnovation.com

Johnson & Johnson Innovation, the Texas Medical Center, and AngelMD have teamed up to launch the Breakthrough Medical Technologies QuickFire Challenge, which is looking for game-changing medical device ideas from all over the world for a chance to win prizes.

The winner — or winners — will "receive up to $250,000 in convertible notes funding from TMC, entry to the TMCx accelerator program, one year of residency at JLABS @ TMC in Houston, Texas, and access to the Johnson & Johnson, Innovation - JLABS global ecosystem," according to the website. Also on the line — an additional convertible note investment up to $100,000 from AngelMD's Catalyst Fund.

The competition is looking for innovations within a wide range of health technologies, from oncology to 3D printing.

Houston hospital ranks No. 1 in the state for being one of America's Best Employers

Courtesy of Methodist Hospital/Facebook

Forbes partnered with market research company Statista to identify the best employers in each state. In Texas, Houston was represented at the top. Houston Methodist ranked as the number one company on the Texas list.

Royal Dutch Shell, which ranks at No. 11, is the next Houston-headquartered company on the list, followed by The University of Texas Health Science Center at Houston (No. 19), Katy Independent School District (No. 22), and Texas Children's Hospital (No. 23.)

HCC recognized for innovation of the year

Photo courtesy of HCC

Houston Community College received the Innovation of the Year Award from the League for Innovation in the Community College. HCC won for its Zero Textbook Degree initiative, which launched in 2017 and has grown from 28 to 98 sections across five HCC campuses.

"The Z-Degree program is managed by an entire group of hardworking and forward-thinking HCC faculty who are all deserving of the accolades currently bestowed on them," says Chancellor Cesar Maldonado in a news release.

Textbook prices have increased 88 percent since 2006, according to the Bureau of Labor Statistics, and, according to the release, textbooks could end up costing some HCC students more than their tuition.

Rice University hosts inaugural program for future entrepreneurs

Photo courtesy of Lilie



Rice's Liu Idea Lab for Innovation and Entrepreneurship got a jump on molding its young minds. Lilie hosted 44 incoming freshmen as a part of its inaugural Lilie Change Maker Summit. For four days, the to-be students had the opportunity to get get a taste of the program and entrepreneurialism through workshops, guest speakers, and more.

The summit was led by Jamie Jones, executive director of Lilie, and Hesam Panahi, lecturer in entrepreneurship at Rice's Jones Graduate School of Business and a faculty member at Lilie.

"We truly believe this will be a game changer in the Rice entrepreneurial ecosystem," says Caitlin Bolanos, associate director at Lilie, in an email to InnovationMap. "We were able to connect with these students and build loyalty before they even officially started in the fall, and the students are so pumped to have found each other and to continue working on their ideas while at Rice."

From enlightening talks to anniversary celebrations, here's where you need to be in January. Getty Images

Updated: 10 can't-miss innovation events for January

Where to be

Houston's innovation community is starting 2019 strong with plenty of business professional events.

If you know of innovation-focused events for February, email me at natalie@innovationmap.com with the details.

1. How to Start a Startup with Roberto Moctezuma, founder & CEO of Fractal River

Thinking 2019 is the year you finally turn your business idea into a startup? Station Houston wants to help. It's free to attend this discussion lead by Roberto Moctezuma, the founder and CEO of Houston-based Fractal River, an advisory firm. The talk will focus on identifying problems, determining market needs, learning important metrics, and more.

The event is from 6 to 7 pm on Tuesday, January 8, at Station Houston (1301 Fannin St., Suite 2440).

Learn more here.

2. January U.S. Oil & Gas Blockchain Forum Luncheon

For the first event of the year, the U.S. Oil & Gas Blockchain Forum is focusing on how blockchain can help the energy industry. Guest speakers are Andrew Bruce, CEO and founder of Houston-based Data Gumbo, and Rebecca Hofmann, blockchain strategist at Equinor.

The luncheon is from 11:30 am to 1:30 pm on Tuesday, January 15, at the Equinor Auditorium (2107 CityWest Blvd). Tickets to attend are $50.

Learn more here.

3. Salesforce Essentials Workshop: Houston

Attention small business owners: Salesforce has a workshop designed for you. Learn about the platform and how it can help your business strategy over lunch.

The workshop isn Tuesday, January 15, from noon to 2 p.m. at The Cannon (1336 Brittmoore Road) and is free to attend.

Learn more here.

4. Society of Petroleum Engineers Women-in-Energy Congress

Energy industry ladies take center stage of a full-day event focused on women in oil and gas. Susan Dio, chairman and president of BP America, will deliver the keynote address before the rest of the day's panels and presentations begin.

This event is January 18, from 8 a.m. to 3:30 p.m., at the Houston Community College West Houston Institute (2811 Hayes Road).

Learn more here.

5. Houston Startup Demo Day

Three Houston startups will present their product and business plan at The Station's monthly demo day. The companies and judges are still being determined, but the event details are finalized.

Hear the pitches on Wednesday, January 23, from 6 to 8 p.m., at Station Houston (1301 Fannin Street, Suite 2440). The event is free to attend.

Learn more here.

6. NRLC Workshop: Pitching Part 2: The Physical Pitch with Beth O'Sullivan

If you thought you were pitch perfect, think again. Beth O'Sullivan, a management senior lecturer at Rice University's Jones Graduate School of Business, is giving a free lecture on the art of pitching your company. The Liu Idea Lab for Innovation and Entrepreneurship is offering the event.

The lecture will be from 4 to 5:30 pm on Wednesday, January 23, at the Liu Idea Lab for Innovation and Entrepreneurship (6100 Main Street Cambridge Office Building, Suite 130).

Learn more here.

7. Women Entrepreneurs Pitch Party at The Cannon

Calling all angel investors — The Cannon Ventures would like to introduce you to a few female entrepreneurs this month. InnovationMap is a media partner for the event, and the goal is to generate connections between the entrepreneurs and potential investors.

The event takes place on Thursday, January 24, from 6:30 to 9 p.m. at The Cannon (1336 Brittmoore Road).

If you're an interested investor and would like to attend, email Jake Askew at jaskew@cannonventureshouston.com.

8. Oil & Gas Happy Hour Hosted by OGGN + The Cannon

Grab a beer and some bites at Oil & Gas Global Network's monthly happy hour — this time in collaboration with Houston-based The Cannon.

Join oil and gas professionals at The Cannon (1336 Brittmoore Road) on Tuesday, January 29, from 6 to 9 p.m. Tickets are $10 for this happy hour event, and proceeds go to Redeemed Ministries, a local charity to help human trafficking victims.

Learn more here.

9. Station Houston 3.0 and Launch Party

As Station Houston officially becomes a nonprofit on January 1, and, in preparation for its move to the Midtown Innovation District, the organization is revealing Station Houston 3.0 to start 2019 with. The free event is Wednesday, January 30, from 6 to 8 pm at Station Houston (1301 Fannin St., Suite 2440).

Guests can mingle until the short program and announcement, which is followed by light bites. Station will also be showing off Houston's first VR Lab and its new space.

Learn more here.

10. Inaugural meeting of the Houston Industrial Digital Transformation & IoT Meetup

Calling all digital and tech innovation leaders in oil and gas or utilities — there's a new group for you to join. The Houston Industrial Digital Transformation and IoT Meetup formed to bring leaders of industrial innovation together for collaboration and so that they can learn from each other's digital transformations.

The inaugural meetup is from 6 to 8 pm on Wednesday, January 30, at ChaiOne HQ (9 Greenway Plaza, Suite 850). It's free to attend.

Learn more here.

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Texas A&M University reveals plans for $546M medical complex in Houston

coming soon

Texas A&M University has announced a new three-building project in the Texas Medical Center that will bring a renovated space for its Engineering Medicine program, student housing, parking, retail, and more.

The $546 million complex will be funded in part by a public-private partnership, according to a news release from the university. The project includes one 18-story building to be purchased and renovated for $145 million, and an additional $401 million will go toward constructing two new buildings.

"The Board of Regents of the Texas A&M University System recognized an opportunity in Houston to help Texans and contribute more to the global medical community," says Elaine Mendoza, chairman of the Board of Regents of the Texas A&M University System, in the news release. "We are eager and fortunate to further enhance the world's greatest medical center through this endeavor."

The first of the three buildings to debut will be the EnMed renovation project at 1020 Holcombe Blvd. This project, which had previously been announced, is expected to deliver by this summer and should be monumental for the already successful program, says Bob Harvey, president and CEO of the Greater Houston Partnership, in a statement.

"Texas A&M's EnMed program fits right into what we are doing in Houston," Harvey says. "Our city has long been recognized as a destination for world-class health care and cutting-edge research, thanks to the incredible institutions in the Texas Medical Center. Houston is also becoming known as an attractive location for both mature and emerging life science and biotech companies. We are, indeed, becoming the 'third coast' for life sciences."

A&M TMC The first of the three buildings is expected to be complete this summer. Photo courtesy of Texas A&M University System

The two new construction buildings will be paid for through public-private partnerships. The student housing building, a 19-story building planned to have 572 units with 704 beds in a 365,000 square-foot space, will be completed by June 2022, according to the release. The building will also include a 3,444-spot parking garage. Students from A&M campuses will get priority housing, but students at other institutions will also be allowed spots if available.

"We saw a need for student housing and medical offices in Houston. Plus, our EnMed students needed the facilities to create the latest medical devices," says Greg Hartman, a vice chancellor at Texas A&M University System and interim senior vice president of the Texas A&M Health Science Center, in a news release. "So, we began the process of expanding the Texas A&M footprint in Houston and I believe the work done by Aggies in Houston will be life-changing for a lot of people."

The third component of the plans includes a 587,000-square-foot, 30-floor Integrated Medical Plaza — another public-private partnership — and it has a June 2023 expected completion. Thirteen of the stories will be parking, and 72,000 square feet of space will be for retail use, while 8,700 square feet will be green space.

According to the release, the developer for the two new construction projects is Houston-based Medistar Corp., which is run by CEO Monzer Hourani. New York-basedAmerican Triple I Partners is on the financing team and was founded by Henry Cisneros, a Texas A&M alumnus.

Representatives from both the school and the city see the potential impact of the complex for medical innovations.

"Last year, Houston had its best year ever in terms of attracting venture capital to the region," Harvey says in his statement on the news. "This program and this facility will provide one more reason for major VCs to give Houston's innovative companies a look – and for talented students, researchers, and entrepreneurs to make Houston their home."

Dr. M Katherine Banks, who serves the university of vice chancellor of engineering and national laboratories at the Texas A&M System, notes in the release how the EnMed program has set up its students for breakthrough medical device innovation.

"I expect to see transformative ideas generated by Texas A&M's broadened presence in Houston," says Dr. Banks in the release.

Houston cancer-fighting researchers granted over $30 million from statewide organization

just granted

The Cancer Prevention and Research Institute of Texas has again granted millions to Texas institutions. Across the state, cancer-fighting scientists have received 55 new grants totaling over $78 million.

Five Houston-area institutions — Baylor College of Medicine, the University of Houston, The University of Texas Medical Branch at Galveston, The University of Texas Health Science Center at Houston, and the The University of Texas MD Anderson Cancer Center — have received around $30 million of that grand total.

"These awards reflect CPRIT's established priorities to invest in childhood cancer research, address population and geographic disparities, and recruit top cancer research talent to our academic institutions," says Wayne Roberts, CPRIT CEO, in a news release. "I'm excited about all the awardees, particularly those in San Antonio, a region that continues expand their cancer research and prevention prowess. San Antonio is poised to have an even greater impact across the Texas cancer-fighting ecosystem."

Four grants went to new companies that are bringing new technologies to the market. Two companies with a presence in Houston — Asylia Therapeutics and Barricade Therapeutics Corp. — received grants in this category.

Last fall, CPRIT gave out nearly $136 million to Texas researchers, and, to date, the organization has granted $2.49 billion to Texas research institutions and organizations.

Here's what recent grants were made to Houston institutions.

Baylor College of Medicine

  • $900,000 granted for Feng Yang's research in targeting AKT signaling in MAPK4-high Triple Negative Breast Cancer (Individual Investigator Award)
  • $897,527 Hyun-Sung Lee's research for Spatial Profiling of Tumor-Immune Microenvironment by Multiplexed Single Cell Imaging Mass Cytometry (Individual Investigator Award)
  • $899,847 for Joshua Wythe's research in targeting Endothelial Transcriptional Networks in GBM (Individual Investigator Award)

University of Houston

  • $890,502 for Matthew Gallagher's research in Transdiagnostic Cognitive Behavioral Therapy for Smokers With Anxiety and Depression (Individual Investigator Research Award for Prevention and Early Detection)
  • $299,953 for Lorraine Reitzel's research in Taking Texas Tobacco Free Through a Sustainable Education/Training Program Designed for Personnel Addressing Tobacco Control in Behavioral Health Settings (Dissemination of CPRIT-Funded Cancer Control Interventions Award)

The University of Texas Medical Branch at Galveston

  • $1,993,096 for Abbey Berenson's research in maximizing opportunities for HPV vaccination in medically underserved counties of Southeast Texas (Expansion of Cancer Prevention Services to Rural and Medically Underserved Populations)

The University of Texas Health Science Center at Houston

  • $900,000 for Melissa Aldrich's research on "Can Microsurgeries Cure Lymphedema? An Objective Assessment" (Individual Investigator Award)
  • $900,000 for John Hancock's research in KRAS Spatiotemporal Dynamics: Novel Therapeutic Targets (Individual Investigator Award)
  • $900,000 for Nami McCarty's research in targeting Multiple Myeloma Stem Cell Niche (Individual Investigator Award)
  • $1.96 million for Paula Cuccaro's research in Expanding "All for Them": A comprehensive school-based approach to increase HPV vaccination through public schools (Expansion of Cancer Prevention Services to Rural and Medically Underserved Populations)

The University of Texas MD Anderson Cancer Center

  • $900,000 for Laurence Court's research in Artificial Intelligence for the Peer Review of Radiation Therapy Treatments
  • $900,000 for John deGroot's research in targeting MEK in EGFR-Amplified Glioblastoma (Individual Investigator Award)
  • $900,000 for Don Gibbons's research in Investigating the Role ofCD38 as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer (Individual Investigator Award)
  • $900,000 for John Heymach's research in Molecular Features Impacting Drug Resistance in Atypical EGFR Exon 18 and Exon 20 Mutant NSCLC and the Development of Novel Mutant- Selective Inhibitors (Individual Investigator Award)
  • $900,000 for Zhen Fan's research in Development of a Novel Strategy for Tumor Delivery of MHC-I-Compatible Peptides for Cancer Immunotherapy (Individual Investigator Award)
  • $900,000 for Jin Seon Im's research in off the shelf, Cord-Derived iNK T cells Engineered to Prevent GVHD and Relapse After Hematopoietic Stem Cell Transplantation (Individual Investigator Award)
  • $900,000 for Jae-il Park's research in CRAD Tumor Suppressor and Mucinous Adenocarcinoma (Individual Investigator Award)
  • $900,000 for Helen Piwnica-Worms's research in Single-Cell Evaluation to Identify Tumor-stroma Niches Driving the Transition from In Situ to Invasive Breast Cancer (Individual Investigator Award)
  • $898,872 for Kunal Rai's research in Heterogeneity of Enhancer Patterns in Colorectal Cancers- Mechanisms and Therapy (Individual Investigator Award)
  • $900,000 for Ferdinandos Skoulidis's research in Elucidating Aberrant Splicing-Induced Immune Pathway Activation in RBMl0-Deficient KRAS-Mutant NSCLC and Harnessing Its Potential for Precision Immunotherapy (Individual Investigator Award)
  • $887,713 for Konstantin Sokolov's research in High-Sensitivity 19F MRI for Clinically Translatable Imaging of Adoptive NK Cell Brain Tumor Therapy (Individual Investigator Award)
  • $900,000 for Liuqing Yang's research in Adipocyte-Producing Noncoding RNA Promotes Liver Cancer Immunoresistance (Individual Investigator Award)
  • $1.44 million for Eugenie Kleinerman's research in Doxorubicin-Induced Cardiotoxicity: Defining Blood and Echocardiogram Biomarkers in a Mouse Model and AYA Sarcoma Patients for Evaluating Exercise Interventions (Individual Investigator Award for Cancer in Children and Adolescents)
  • $2.4 million for Arvind Dasari's research in Circulating Tumor DNA- Defined Minimal Residual Disease in Colorectal Cancer (Individual Investigator Research Award for Clinical Translation)
  • Targeting Alterations of the NOTCH! Pathway in Head and Neck Squamous Cell Carcinoma (HNSCC)(Faye Johnson) - $1.2 million (Individual Investigator Research Award for Clinical Translation)
  • $2.07 million for Florencia McAllister's research in Modulating the Gut- Tumor Microbial Axis to Reverse Pancreatic Cancer Immunosuooression (Individual Investigator Research Award for Clinical Translation)
  • $2 million to recruit Eric Smith, MD, PhD, to The University of Texas MD Anderson Cancer Center from Memorial Sloan Kettering Cancer Center (Recruitment of First-Time, Tenure-Track Faculty Members Award)
  • $2 million for Karen Basen-Engquist's research in Active Living After Cancer: Combining a Physical Activity Program with Survivor Navigation (Expansion of Cancer Prevention Services to Rural and Medically Underserved Populations)


Seed Awards for Product Development Research

  • Houston and Boston-based Asylia Therapeutics's Jeno Gyuris was granted $3 million for its development of a Novel Approach to Cancer Immunotherapy by Targeting Extracellular Tumor- derived HSP70 to Dendritic Cells
  • Houston-based Barricade Therapeutics Corp.'s Neil Thapar was granted $3 million for its development of a First-In-Class Small Molecule, TASIN, for Targeting Truncated APC Mutations for the Treatment of Colorectal Cancer (CRC)

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