A Houston-based app, SAFE 2 SAVE, rewards drivers for putting their phones away while driving. Pexels

Between 2016 and 2017, distracted driving accidents in Harris County rose 62 percent, according to the Texas Department of Transportation, and a local hospital system is stepping up to keep drivers and their passengers out of their emergency rooms.

Memorial Hermann's critical care air transport service Life Flight is partnering with app SAFE 2 SAVE to reward drivers who keep their minds focused and their eyes on the road. The app launched in Houston in January of 2016, and wants to expand to other Texas markets this year.

"Part of our role as trusted providers of high-quality trauma care for our community is to educate and empower people across the region to change behaviors that cause preventable traumas," Tom Flanagan, Memorial Hermann's vice president of Trauma Service Line and System Integration, says in a press release. "We are tapping into the technology that has become such a large part of people's lives and coincidentally, a major part of distracted driving."

The idea for SAFE 2 SAVE began when College Station pastor's wife Marci Corry, who previously worked for Merck — a large pharmaceutical company, met with a college student she was mentoring to discuss how to help the student's peers detach from their phones. They agreed that incentives, particularly food, were the key, and not just for college kids. Corry was inspired by the news of a Chick-fil-A franchise that used a "Cell Phone Coop" challenge to get customers to talk to each other and rewarded them for restricting their cell use with free ice cream at the end of the meal. "Let's do an app version of that!" she remembers saying at the time.

That was October 2016. In that time, the app has blown up to include a fan base of more than 148,000 users. The company has 20 employees, including two based full-time in Houston.

"We're so fortunate we have a product that everyone is interested in," says vice president of operations, Christina Rudolph. "We have such a unique place in the market because everyone likes our app. There aren't a lot of products to change behavior and food is such a motivator."

The sales team at SAFE 2 SAVE works hard to make the rewards appealing to a broad swath of users, not just college students, so while there are discounts at Chick-fil-A and Dave & Buster's, it's far from the whole story. In Houston, food options include free dishes at State Fare and discounts at Cacao & Cardamom, but also 20 percent off at Rooftop Cinema Club or discounted classes at Pure Barre.

For every minute of driving over 10 miles per hour without using their phones, users rack up two points. As long as users set navigation apps and music before they start driving, they can use those, too.

They can also earn more by referring friends. With enough friends on board, it's easy to organize a competition, a great incentive for family and friends to keep each other in check about safe driving.

"To get people to live a life that's less distracted, there's a ripple effect for users," Corry says of the human connection the app helps to foster.

SAFE 2 SAVE launched in Houston in January of 2018. Before that, Corry connected with Memorial Hermann at a Lifesavers National Conference on Highway Safety Priorities.

"They said, 'We want this to stop happening. We don't want these people being pushed through our door on a stretcher and this is epidemic in Houston,'" Corry says.

The sponsorship means that whenever users in Houston open the SAFE 2 SAVE app, they are met with the words, "Is it really worth it? Memorial Hermann Life Flight says no." The hospital logo is accompanied by a photo the user downloads of themselves with a loved one to remind themselves why their behavior matters.

"Our first step is to continue to go deep in Houston. If you can win Houston, you can win anywhere — it's the most distracted city in the nation," Corry says.

Already expanded to San Antonio, the company hopes to expand to Austin and Dallas this year. Once they hit 500,000 users, online brands are likely to join, making it easier to go nationwide. But until then, Houston has some serious work to do.


Marci Corry (left) started SAFE 2 SAVE in January of 2018. Christina Rudolph is the company's vice president of operations.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.