Tammi Wallace of the Greater Houston LGBT Chamber of Commerce is a panelist on The Ion's Pride in Tech event. Photo via LinkedIn

It's Pride Month, and the Houston tech community is celebrating its LGBTQIA+ community — as well as addressing some challenges faced within the business arena.

The Ion Houston, Austin-based Pride.VC, and Houston-based Sesh Coworking are collaborating on a Pride in Tech event, tomorrow, June 24, at noon at the Ion. It's free to attend and all is welcome. The Ion is also encouraging attendees to come early for a cup of coffee at Common Bond for the weekly Cup of Joey networking happy hour from 8:30 to 10:30 am.

The event will feature a panel moderated by Sesh's Maggie Segrich and Meredith Wheeler, and will tackle topics around how Houston can do more to build a truly inclusive business community. The panelists include

Wallace, who co-founded the Greater Houston LGBT Chamber of Commerce in 2016, joined InnovationMap for a quick Q&A ahead of the event.

InnovationMap: What kind of challenges do LGBTQIA+ founders in Houston face these days?

Tammi Wallace: First, LGBTQIA+ founders need to be at the table and have a voice. When we launched the Greater Houston LGBT Chamber of Commerce in 2016, our primary goal was to make sure we were seen, heard and engaged.

A seat and a voice at the table matters because LGBTQIA+ founders often lack visibility in the broader economic ecosystem and continue to experience discrimination. This means they cannot engage with their full and authentic selves as entrepreneurs and experience unique challenges. More specifically, they face challenges with access to venture capital and angel investment funds and these entrepreneurs lack strong LGBTQIA+ role models and mentors.

In fact, some LGBTQIA+ business owners never come out because they fear losing customers or clients. We hear stories all the time about LGBTQIA+ founders not seeking either traditional or non-traditional funding because they fear that they will have to out themselves in the process and fear discrimination and a lack of acceptance in the process. Disclosing personal information, such as financial information, in some cases, can effectively out them as an LGBTQIA+ person. Funding paths must be fully inclusive and ensure that the process is viewed from the lens of the LGBTQIA+ entrepreneur and how that can impact their access to capital.


    IM: How would you recommend these founders find the community and support they are looking for? 

    TW: Definitely get involved with the Houston LGBT Chamber of Commerce. Since 2016, the chamber has been working to build a strong community to support LGBTQIA+ entrepreneurs and get them access to resources to help their businesses grow and thrive.

    We create connections and give LGBTQIA+ entrepreneurs a space and place to walk through the door as their full and authentic selves. Through the Chamber, LGBTQIA+ founders can find support, whether from other entrepreneurs, mentors and Corporate Partners. We collaborate with the National LGBT Chamber of Commerce (NGLCC) as well as the other LGBTQIA+ chambers in Texas to drive connections and build a strong LGBTQIA+ business network across the country and the state.

    We encourage LGBTQIA+ businesses to get LGBTBE® Certified as well which offers even more connection with other certified businesses, major corporations and other key stakeholders and mentoring opportunities with major companies. We can help these founders get started with the LGBTBE® certification process and tap into national, regional and statewide resources.

    IM: How do you recommend startup development organizations, investors, and other businesses become better allies to the LGBTQIA+ startup community? 

    TW: Ensure that LGBTQIA+ entrepreneurs and business and community leaders are engaged with your organization. Organizations like the Greater Houston LGBT Chamber of Commerce and the Ion are working "boots on the ground" to support the LGBTQIA+ business community and can offer the opportunity for meaningful collaboration. We also recommend advocating for others -- when you are around a table, look around and if the LGBTQIA+ community is not being represented, ask why.

    If representation is around the table, be intentional to ensure that we have a voice. As organizations that are involved in Houston's economic ecosystem, be strong and visible advocates for the LGBTQIA+ business community through engagement of businesses and the Chamber throughout the year. Be engaged -- not just during Pride Month, but twelve months out of the year.

    Whether a startup, investor or a business, you can help raise the profile for LGBTQIA+ businesses and the LGBTQIA+ business movement.

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    Houston brain health co. secures $6.5M for rare disease study

    neuro funding

    Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

    The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

    Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

    The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

    The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

    “Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

    11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

    Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

    Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

    27 Houston companies make Fortune 500 for 2026, led by energy giants

    Houston HQs

    Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

    Houston is a giant among U.S. hubs for corporate headquarters.

    The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

    Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

    “Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

    The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

    Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

    • No. 9 ExxonMobil
    • No. 21 Chevron
    • No. 29 Phillips 66
    • No.55 Sysco
    • No. 75 ConocoPhillips
    • No. 89 Enterprise Products Partners
    • No. 103 Plains GP Holdings
    • No. 133 Hewlett Packard Enterprise
    • No. 149 NRG Energy
    • No. 157 Quanta Services
    • No. 164 Baker Hughes
    • No. 173 Occidental Petroleum
    • No. 179 Waste Management
    • No. 201 EOG Resources
    • No. 204 Group 1 Automotive
    • No. 207 Halliburton
    • No. 223 Cheniere Energy
    • No. 236 Corebridge Financial
    • No. 262 Targa Resources
    • No. 266 Kinder Morgan
    • No. 388 Westlake
    • No. 435 CenterPoint Energy
    • No. 438 APA
    • No. 440 Comfort Systems USA
    • No. 455 NOV
    • No. 488 KBR
    • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

    The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

    As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

    Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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    This article first appeared on EnergyCapitalHTX.com.