Trivie has closed a $5 million investment round led by Houston-based Cottonwood Venture Partners. Photo via Trivie.com

A Texas-based tech startup that has created an artificial intelligence-enabled tool that gamifies corporate training and education has closed its most recent funding round thanks to a Houston investor.

Trivie as announced its $5 million series A investment round led by Houston-based Cottonwood Venture Partners, an investment firm that has a portfolio of technology companies that are providing digital solutions within the energy industry. Trivie will use the new funds to scale its product and expand across industries, from energy and manufacturing to hospitality, healthcare, consumer goods, and more.

"The Trivie team's success to date has been remarkable and we are humbled to partner with them to expand Trivie's reach as organizations increasingly look to maximize knowledge retention, particularly as it relates to health and safety," says Jeremy Arendt, managing partner of CVP, in a news release.

Now, as more employees are working from home than ever before, relevant training is crucial and at the top of mind for business leaders. Trivie's clients include Subway, Phillips66, Anheuser-Busch, to name a few.

"At Trivie, our mission is to ensure that every employee at every organization can be at their very best because what they have been taught, they remember, and what they have said is understood," says Lawrence Schwartz, CEO, and co-founder at Trivie, in a news release. "We are extremely excited to partner with Cottonwood Venture Partners to help us expand our footprint in the Fortune 1000 and to continue to execute on that mission."

One of Trivie's founders, Leland Putterman, who is based in Houston, first had the idea for a consumer-facing trivia game 18 years ago. When the app rolled out in 2013, it garnered more than three million downloads. As COVID-19 has brought new compliance guidelines to the forefront of every industry, Trivie was quick to make the CDC's coronavirus guidelines available to all of its clients for no additional charge to be used across their entire employment bases.

Additionally, Trivie prioritizing its user's ability to connect in a time of social distancing and working from home.

"The only way to maintain that company culture and close communication with confidence is to use something like Trivie," Putterman previously tells InnovationMap. "There's no feedback loop right now. The only way to bridge that gap is to have something like Trivie that's the glue."

This week's Houston innovators to know includes Aleece Hobson of HX Venture Fund, Leland Putterman of Trivie, and Eleonore Cluzel of gBETA Houston. Photos courtesy

3 Houston innovators to know this week

who's who

This week's roundup of who's who in Houston innovation include the HX Venture Fund's newest team member, a startup founder whose app is gamifying corporate training, and a Houston accelerator leader who's pivoted to digital.

Aleece Hobson, venture partner at the HX Venture Fund

Aleece Hobson joined the HX Venture Fund as venture partner. Photo courtesy of HXVF

The HX Venture Fund has expanded its portfolio of venture capital finds its invested in, and with that came a new team member for the fund of funds. Managing director Sandy Guitar — who runs the fund with Guillermo Borda — brought on Houston native Aleece Hobson as venture partner.

"Aleece joining is a phenomenal step for us — a dedicated resource and venture partner on activation," says Guitar on the hire. "I think it speaks to the seriousness of purpose we have to make this not just an investment platform, but one that moves the needle on Houston." Read more.

Leland Putterman, co-founder of Trivie Inc.

Trivie, which gamifies corporate training, has launched a new way for employees to connect with remote learning amid the pandemic. Photo via Trivie.com

Texas-based corporate training tool Trivie already had many clients with needs for safety training, COVID-19 has brought new compliance guidelines to the forefront of every industry. Currently, Trivie has made the CDC's coronavirus guidelines available to all of its clients for no additional charge to be used across their entire employment bases.

Additionally, with most of America's workforce working from home, Putterman expressed that it's common for employees to feel disconnected.

"The only way to maintain that company culture and close communication with confidence is to use something like Trivie," he says. "There's no feedback loop right now. The only way to bridge that gap is to have something like Trivie that's the glue." Read more.

Eléonore Cluzel, director of gBETA Houston

Eléonore Cluzel, director of gBETA Houston, joins the Houston Innovators Podcast to share how the cohort has been going — and to introduce each member of the inaugural cohort. Photo courtesy of gBETA

Things aren't going according to plan for Eléonor Cluzel, who is running the inaugural gBETA Houston cohort virtually. While it isn't ideal, Cluzel shares on the Houston Innovator's Podcast how she's adapted the program for digital — as well as introduces the five Houston companies in the program.

"Going virtual was a really good pivot on our end. I think that the cohort has adjusted very well," Cluzel says on the Houston Innovators Podcast. "It is tough. They put tremendous effort into it and I'm proud to be working with them." Read more.

Trivie, which gamifies corporate training, has launched a new way for employees to connect with remote learning amid the pandemic. Photo via Trivie.com

Houston founder's corporate training app shifts to enhance remote learning for employees

there's an app for that

How much of corporate training do employees actually remember? Texas-based Trivie, a training reinforcement app, sought to not only answer that question, but change the results entirely. Using adaptive learning and gamification, the Trivie app is reshaping online learning while the world adapts to remote working in a global pandemic.

According to Gallup Panel data, 62 percent of Americans currently say they have worked from home during the coronavirus pandemic. In a connected yet socially distanced environment, corporations are choosing to automate remote learning and disseminate critical COVID-19 guidelines with the help of Trivie.

One of Trivie's founders, Leland Putterman, who is based in Houston, first had the idea for a consumer-facing trivia game 18 years ago. When the app rolled out in 2013, it garnered more than three million downloads. Like anything in technology, App Store games were diversifying. Competing applications were deviating into in-app purchases — a move Putterman's app hadn't planned.

Rather than sink under the pressures of an unfit revenue model, the founders pivoted to a more fruitful investment in an untapped space: corporate training. After receiving multiple emails from users asking if developers had ever thought of using the app for company training, Putterman jumped into research on information retention and learned that trivia vastly benefits human memory.

With a new business plan and research backed by neuroscientists, the Trivie app launched in 2016. Reaching a broad list of organizations with five to over 40,000 users, Trivie has generated the praise and trust of business goliaths such as Subway, Unilever, and Anheuser-Busch. The app has been used to roll out onboarding, marketing training, safety protocols, sales information, remote learning and more.

"The vast majority of companies and organizations do nothing after a training event," he says, adding that, according to Trivie's own research, the app has found 50 to 75 percent of people had forgotten workplace education within a month. "It makes training one of the least effective business processes out there because everybody knows people don't remember their training unless it gets reinforced."

What if the secret to remembering is forgetting? Studies have shown that re-learning information over time strengthens memory recall.

"The way our solution works is very unique in that we want you to forget so you can re-remember again. The process of re-remembering is what pushes things into durable memory," explains Putterman.

When a company sets up a training on the Trivie app, the program serves each employee personalized training refreshers over time that are balanced with the retention levels of each unique learner. Using adaptive learning, the app prompts employees to remember previous facts until they master the subject.

"The AI [artificial intelligence] on the backend predicts when you're going to forget again, and it automates the whole thing," Putterman says.

In a Trivie control group, half of the test subjects used Trivie and half received basic employee training. Putterman stated the Trivie users typically have 95 percent retention after a month while non-Trivie users show less than 60 percent retention.

Employers can see the results of each Trivie assessment, pinpointed down to individual questions — a feature that is especially crucial for compliance and safety protocol. One of Trivie's university clients published a training on Title IX, where students passed yet 65 percent missed the question: "Whose responsibility is it to gain consent during a sexual encounter?"

When the university received the results, "they were able to see down to that level of detail—and that knowledge gap is pretty darn important," explains Putterman.

"Training is important but nowadays it's mission-critical," he says.

While Trivie already had many clients with needs for safety training, COVID-19 has brought new compliance guidelines to the forefront of every industry. Currently, Trivie has made the CDC's coronavirus guidelines available to all of its clients for no additional charge to be used across their entire employment bases.

Putterman acknowledges the pitfalls of sending out a corporate memo only to hear crickets.

"In a Trivie platform you would send a video, PDF, or word document via Trivie. You'd know people opened it up and after they're required to take a quiz so you know they understand what was in the message," Putterman explains.

An internal discussion board also allows company employees to discuss why the communication is essential to the organization. Another prominent feature of the app is a customizable survey.

"You know as well as I do that there's a ton of anxiety out there [about the coronavirus]. Wouldn't it be nice to push out a survey and then have a discussion around how people are dealing with it?" he questions.

With most of America's workforce working from home, Putterman expressed that it's common for employees to feel disconnected.

"The only way to maintain that company culture and close communication with confidence is to use something like Trivie," he says. "There's no feedback loop right now. The only way to bridge that gap is to have something like Trivie that's the glue."

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Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”

10+ Houston innovation leaders in the spotlight at SXSW 2026

where to be

Houston's innovation scene will be well represented at South by Southwest (SXSW) this month.

The week-long, Austin-based conference and festival will spotlight some of the Bayou City's leaders in health care, energy, space and more. The event kicks off today, March 12, and runs through March 18. The SXSW Innovation Conference will feature keynotes, workshops, mentoring sessions and more throughout various venues in the city.

Here's who to see and when and where to find them:

March 12

Aileen Allen, venture partner at Mercury Fund

Mentor Session from 4-5:15 p.m. at Hilton Austin Downtown

Allen will host a mentoring session focused on funding, marketing, advertising, PR and the future of work.

March 13

Heath Butler, partner at Mercury Fund

SXSW Pitch-Smart Cities, Transportation, Manufacturing & Logistics from 2:30-3:30 p.m. at the J.W. Marriott

Butler will judge five innovative startups as they pitch their solutions to advance smart cities, enhance transportation systems, modernize manufacturing, transform logistics, and strengthen government infrastructure and civic operations.

Jonathan Cirtain, CEO and president of Axiom Space

The Clock is Ticking for Space - Replacing the ISS from 4-5 p.m. at the J.W. Marriott

Cirtain will discuss Axiom's pursuit of building the world’s first commercial space station.

March 14

Jesse Martinez, founder and CEO of LSA Global

SXSW Pitch-Intelligent Systems, Robotics, & Multisensory Technology from 10-11 a.m. at the J.W. Marriott

Martinez will judge five innovative startups as they pitch their technologies that aim to enhance the way people connect, communicate and share unique life experiences with those around them in a digital ecosystem.

Jennifer Schmitt, head of operations at Rhythm Energy

Powering Texas with Reliable Integrated High-Demand Energy from 10-11 a.m. at Marlow

Schmitt will join a panel to discuss how EirGrid, the state-owned electric power transmission operator in Ireland, is pioneering solutions as the country works toward 80 percent renewable integration by 2030.

Saki Sasagawa, director of business development for JETRO Houston

Now is Japan's Time: Leading the Future with Deep Tech from 10-11 a.m. at the J.W. Marriott

Sasagawa joins a panel that will share real-time insights from diverse perspectives on the forefront of Japan’s deep tech and IP businesses.

March 15

Bosco Lai, CEO and co-founder of Little Place Labs

SXSW Pitch Alumni: Where Are They Now? from 10-11 a.m. at the J.W. Marriott

Lai joins a panel of four former SXSW Pitch winners to share how they leveraged the platform to take their startups to the next level.

Tara Karimi, cofounder and chief science and sustainability officer at Cemvita

South by South America: The Rise of Southern Brazil Tech from 2:30-3:30. p.m. at The Line

Karimi will participate in a panel to discuss how Rio Grande do Sul, Brazil's southernmost state, is attracting elite talent and AI infrastructure and share insights on navigating the next wave of South American tech growth.

March 16

Dr. Pavitra P. Krishnamani, emergency medicine physician at The University of Texas MD Anderson Cancer Center

Viva La Revolution: How the Digital Age is Transforming Wellness from 11:30 a.m.-12:30 p.m. at Hilton Austin Downtown

Krishnamani will discuss the latest advancements and policies that can accelerate the digital age of health care, such as wearables, telehealth and artificial intelligence.

March 18

Charlie Childs, co-founder and CEO of Intero Biosystems

Spinning Out: What It Takes to Build a University Startup from 2:30-3:30 p.m. at The Line

Childs will join founders who spun their companies out of the University of Michigan to share the real story of navigating IP, early capital, team building, market validation and the “valley of death.”

Dr. James Allison, regental chair of immunology and director of The Allison Institute at The University of Texas MD Anderson Cancer Center

Dr. Padmanee Sharma, professor in the Department of Genitourinary Medical Oncology, Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center

Beyond Checkpoints: Immunotherapy’s Next Act from 2:30-3:30 p.m. at the J.W. Marriott

Allison and Sharma will sit down with 21-year-old, Stage 4 cancer survivor Sharon Belvin and Time Magazine journalist Alice Park will discuss the future of immunotherapy and what challenges remain.

Last year, Houston startups Little Places Labs and Helix Earth won top prizes in their respective categories at the prestigious SXSW Pitch event, held this year from March 13-14. No Houston startups were named finalists to compete in this year's event.

NASA revamps Artemis moon landing program by modeling it after Apollo

To the moon

NASA is revamping its Artemis moon exploration program to make it more like the fast-paced Apollo program half a century ago, adding an extra practice flight before attempting a high-risk lunar landing with a crew in two years.

The overhaul in the flight lineup came just days after NASA’s new moon rocket returned to its hangar for more repairs, and a safety panel warned the space agency to scale back its overly ambitious goals for humanity’s first lunar landing since 1972.

Artemis II, a lunar fly-around by four astronauts, is off until at least April because of rocket problems.

The follow-up mission, Artemis III, had been targeting a landing near the moon’s south pole by another pair of astronauts in about three years. But with long gaps between flights and concern growing over the readiness of a lunar lander and moonwalking suits, NASA’s new administrator Jared Isaacman announced that mission would instead focus on launching a lunar lander into orbit around Earth in 2027 for docking practice by astronauts flying in an Orion capsule.

The new plan calls for a moon landing — potentially even two moon landings — by astronauts in 2028.

“Everybody agrees. This is the only way forward,” Isaacman said.

The hydrogen fuel leaks and helium flow problems that struck the Space Launch System rocket on the pad at NASA's Kennedy Space Center in February also plagued the first Artemis test flight without a crew in 2022.

Another three-year gap was looming between Artemis II and the moon landing by astronauts as originally envisioned, Isaacman said.

Isaacman stressed that “it should be incredibly obvious” that three years between flights is unacceptable. He'd like to get it down to one year or even less.

Isaacman, a tech billionaire who bought his own trips to orbit and performed the world’s first private spacewalk, took the helm at NASA in December.

During NASA’s storied Apollo program, he said, astronauts’ first flight to the moon was followed by two more missions before Neil Armstrong and Buzz Aldrin landed on the moon. What's more, he added, the Apollo moonshots followed one another in quick succession, just as the earlier Projects Mercury and Gemini had rapid flight rates, sometimes coming just a few months apart.

Twenty-four Apollo astronauts flew to the moon from 1968 through 1972, with 12 of them landing.

“No one at NASA forgot their history books. They knew how to do this," Isaacman said. “Now we're putting it in action.”

To pick up the pace and reduce risk, NASA will standardize its Space Launch System rockets moving forward, Isaacman said. These are the massive rockets that will launch astronauts to the moon aboard Orion capsules. At the same time, Elon Musk's SpaceX and Jeff Bezos' Blue Origin are speeding up their work on the landers needed to get the astronauts from lunar orbit down to the surface.

Isaacman said next year will see an Orion crew rendezvousing in orbit around Earth with SpaceX's Starship, Blue Origin's Blue Moon or both landers. It's similar to the methodical approach that worked so well during Apollo in the late 1960s, he noted. Apollo 8, astronauts' first flight to the moon, was followed by two more missions before Armstrong and Aldrin aimed for the lunar surface.

“We should be getting back to basics and doing what we know works,” he said.

The Aerospace Safety Advisory Panel recommended that NASA revise its objectives for Artemis III “given the demanding mission goals.” It’s urgent the space agency do that, the panel said, if the United States hopes to safely return astronauts to the moon. Isaacman said the revised Artemis flight plan addresses the panel's concerns and is supported by industry and the Trump administration.