The new $16 million Comcast facility is another feather in the cap of Fort Bend County, which is booming with new business. Courtesy of Comcast

At Comcast's new $16 million technology center in Missouri City, technicians for the internet and cable TV provider can "test drive" new product and services at a demo lab and can take classes at Comcast University. It's a far cry from the stereotypical workplace of the "cable guy."

The center represents a cutting-edge expansion for Comcast — and represents yet another feather in the economic-growth cap of Missouri City and Fort Bend County.

On June 19, officials from Comcast, Missouri City government, and the Fort Bend Economic Development Council debuted the 32,000-square-foot center. The center is at 551 Buffalo Lakes Dr., near the intersection of Texas Freeway and Independence Boulevard. Aside from the demo lab and Comcast University classrooms, the center features more than 100 workstations and 15 conference rooms.

The center employs more than 300 technicians, Comcast Business and Xfinity sales professionals. Service technicians install and maintain internet, video, voice, and home security services for residential and business customers in Missouri City and nearby areas, while network technicians build and maintain Comcast's local fiber-optic system.

Employees at the new center previously worked at other offices in the Houston metro area but live in Missouri City and surrounding communities. More than 1,200 people work at Comcast's 10 technology centers throughout the Houston area.

Michael Bybee, director of external communications at Comcast, says Missouri City was picked for the new center because of its strong economic growth and its proximity to major highways and, ultimately, "to bring our employees closer to customers."

Missouri City and Fort Bend County are gaining more potential Comcast customers by the day. From April 2010 to July 2018, the population of Missouri City grew 12.3 percent, according to the U.S. Census Bureau. For Fort Bend County, the population growth rate during the same period stood at 34.7 percent.

Economic growth has accompanied that population growth. Last year, the Comcast center was among several economic development wins scored by Missouri City. An $85 million, 550,000-square-foot Best Buy distribution center and a 200,000-square-foot Warren Valve warehouse and distribution center were two of the other wins.

Fort Bend County as a whole is enjoying economic success. For instance, discount retailer Dollar Tree said in February that it's building a $130 million distribution center on a 140-acre site in Rosenberg that will employ more than 300 people. The company operates more than 1,600 Dollar Tree and Family Dollar stores in Texas.

The 1.2-million-square-foot distribution center, on Spur 10 near Klosterhoff Road, is scheduled to open in the summer of 2020.

"When you have a company like Dollar Tree seeing the opportunity that we offer, it just adds to our strengths and builds on our assets," Bret Gardella, executive director of Rosenberg Development Corp., said in a Dollar Tree news release.

The economic growth in Missouri City, Rosenberg and other places in Fort Bend County isn't likely to subside, at least for the next several decades. A report from the University of Houston's Hobby School of Public Affairs predicts Fort Bend County will end up being the state's third-fastest-growing county from 2010 to 2050.

"Fort Bend County has continued to top lists for livability and economic success — and there is no sign of slowing down," the Fort Bend Economic Development Council says on its website. "Residents and businesses agree that there's no place better to live or work."

Contributing to Fort Bend County's draw is the presence of five business parks — two in Missouri City, and one each in Rosenberg, Sugar Land, and Stafford. The council touts Fort Bend County as "the hub for industrial development."

Courtesy of Comcast

Aside from the demo lab and Comcast University classrooms, the center features more than 100 workstations and 15 conference rooms.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.