The city's top power players within Houston's energy innovation ecosystem joined virtual SXSW to discuss Houston's life science innovation scene and developing an inclusive ecosystem. Photos courtesy

Another day of SXSW 2021 has concluded, and just like the first day, Houston innovators logged on to discuss technology and innovation that's taking off in town.

The second of the two days of programming focused on the development of the Houston innovation ecosystem — including how the city is factoring in diversity and inclusion into development — with interviews hosted by me, Natalie Harms, editor of InnovationMap. Missed out on the fun? Catch up with a few overheard moments from Houston House or stream the full interviews below.

"“We have to be true to ourselves of what works for Houston. Making sure the DEI is interwoven and in our DNA of our ecosystem so that we don’t make the same mistakes as other cities." — Ashley DeWalt, managing director of DivInc Houston

Video courtesy of the Greater Houston Partnership

Houston has an advantage in developing its innovation ecosystem because it can do so by learning from established ecosystems on the coasts. Locally, that means making diversity and inclusion a top priority. At a virtual SXSW Houston House panel, Ashley DeWalt, managing director of DivInc Houston, and Jan Odegard, interim executive director of The Ion, discuss the importance of prioritizing inclusion in developing Houston's innovation ecosystem. Click here to watch the full interview.

“This pandemic has really highlighted a lot of the health care disparities that are present within our systems. … Houston is in a unique position to address that.” — Fiona Mack, head of JLABS @ TMC

Video courtesy of the Greater Houston Partnership

The Texas Medical Center is the largest medical center in the world with over 10 million patients coming in annually — and JLABS @ TMC is right in the middle of that. With this access to patients and clinical trials, Houston has a lot of potential to attract new innovative companies solving the world's biggest health care problems. At a virtual SXSW Houston House HOU Talk, Fiona Mack, head of JLABS @TMC, discusses the momentum behind health tech innovation in Houston. Click here to watch the full interview.

“Whatever the training is, you have to actually create bias disruptors and points of friction and processes that change behavior. If we don’t have a way to implement what we learn, it doesn’t really change culture.” — LaTanya Flix, senior vice president at the GHP

Video courtesy of the Greater Houston Partnership

In light of the Black Lives Matter movement, corporations of all shapes and sizes were inspired to look inward to address inequity within their workforce — from training to shifts in workplace culture. At a virtual SXSW Houston House HOU Talk, LaTanya Flix, senior vice president of Diversity, Equity and Inclusion (DEI) at the Greater Houston Partnership, shares how she's on a mission to spread mindful DEI initiatives across all of the GHP's member organizations. Click here to watch the full interview.

“I see a world where I’m sitting in a boardroom, and I’m not the only woman anymore.” — Samantha Lewis, principal at Mercury Fund

Video courtesy of the Greater Houston Partnership

Women in venture capital are used to being the only women in the room and are fighting for that not to be the case for future generations. At a virtual SXSW Houston House panel, Sandy Guitar, managing director of the HX Venture Fund moderates a discussion with fellow women in VC, Paige Pitcher, director of innovation at Hines, and Samantha Lewis, principal at Mercury Fund. Click here to watch the full interview.

“There’s an incredible number of innovations that have popped up in Houston, but a lot of them have been centered around solving engineering-type problems at industrial scale — and that still exists, but doesn’t get as much coverage as consumer-facing technologies.” — Josh Pherigo, director of research and data analytics at GHP

Video courtesy of the Greater Houston Partnership

When tracking any sort of progress or growth, business look to their numbers and data. Houston's innovation system is no different. At a virtual SXSW Houston House HOU Talk, Josh Pherigo, director of research and data analytics at the Greater Houston Partnership, dives in deep with the facts and figures of Houston's burgeoning innovation ecosystem by following the venture dollars coming into local startups. Click here to watch the full interview.

“If you look at the density in Houston, being the energy capital of the United States, there are probably few places in the world where you can walk 15 minutes in either direction and talk to about 100 companies that would potentially be customers.” — Matthew Costello, CEO and co-founder of Voyager Portal

Video courtesy of the Greater Houston Partnership

A good startup idea comes from necessity and a way to apply technology to solve problems and shorten business delivery times, and the maritime shipping industry has a lot of opportunities for these types of innovations. At a virtual SXSW Houston House HOU Talk, Matthew Costello, CEO and co-founder of Voyager Portal, sets sail on a conversation about the maritime shipping industry — and how it was ripe with disruption. Click here to watch the full interview.

“You have institutions of exception in Houston where innovation flows from. The question isn’t that it’s not there, it’s how have we been tapping it.” — David Schubert, president of Magnolia Tejas Corp.

Video courtesy of the Greater Houston Partnership

Houston has a burgeoning life science innovation scene — but what's that next step for its development? At a virtual SXSW Houston House HOU Talk, David Schubert, president of Magnolia Tejas Corp. discusses the potential of Houston's world-class oncologists and biotech innovators have to make the city a hub for cancer innovation. Click here to watch the full interview.

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Houston leaps back into top 50 'World's Best Cities' list for 2025

call it a comeback

Lively Houston has regained its rightful place among the top 50 best cities in the world, according to a prestigious new report by Resonance Consultancy.

The Canada-based real estate and tourism marketing advisors ranked Houston the 40th best city worldwide for 2025 in its annual "World's Best Cities" list.

The report quantifies the relative qualities of livability, "lovability," and prosperity for the world's top 100 cities with metropolitan populations of 1 million or more. New to the 10th anniversary edition, Resonance partnered with global market researchers Ipsos to include perception-based data into the rankings, surveying over 22,000 people in 30 countries worldwide to determine "the most desirable places to visit, live or work."

Houston made a major rebound after plummeting to No. 73 in last year's report. In 2022, Houston ranked No. 42.

Resonance refers to its previous "World's Best Cities" reports and its 2024 "America's Best Cities" list – which ranked Houston in the top 10 – when explaining the Bayou City's successes. The report praised Houston's vast cultural diversity and placed a great focus on its economic prosperity, even going so far as to suggest Houston residents make more money "and can sock more away."

"...[W]here America’s fourth-largest city truly takes off is in its economic heft and wealth, ranking No. 9 globally for GDP per Capita and No. 14 for Fortune 500 companies in town," the report said. "All that rolls up into an overall Prosperity index ranking of No. 36, which is even more impressive given the No. 14-ranked Price-to Income Ratio [of the city]."

Elsewhere in Texas, Austin and Dallas also earned spots on the World's Best Cities list for 2025, but only one made a similar rebound from the previous year's rankings. Dallas moved up from No. 66 in last year's report to its current rank as No. 55. Meanwhile, Austin took its first tumble out of the 43rd spot (which it had occupied for two years straight) and now ranks No. 53.

London held onto its crown as the No. 1 best city in the world for 2025, followed by New York (No. 2), Paris (No. 3), Tokyo (No. 4), and Singapore (No. 5).

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This article originally ran on CultureMap.

3 Houston innovators to know this week

who's who

Editor's note: Every week, I introduce you to a handful of Houston innovators to know recently making headlines with news of innovative technology, investment activity, and more. This week's batch includes three innovators across seed investing, energy tech, and health care.

Samina Farid, head of the Houston Chapter of Golden Seeds

Samina Farid of Golden Seeds joins the Houston Innovators Podcast to discuss opportunities in angel investing. Photo courtesy of Golden Seeds

After working in technology in her home country of Pakistan, Samina Farid, who was raised in the United States, found her way to Houston in the '70s where business was booming.

She was recruited to work at Houston Natural Gas — a company that would later merge and create Enron — where she rose through the ranks and oversaw systems development for the company before taking on a role running the pipelines.

"When you're in technology, you're always looking for inefficiencies, and you always see areas where you can improve," Farid says on the Houston Innovators Podcast, explaining that she moved on from Enron in the mid-'80s, which was an exciting time for the industry.

"We had these silos of data across the industry, and I felt like we needed to be communicating better, having a good source of data, and making sure we weren't continuing to have the problems we were having," she says. "That was really the seed that got me started in the idea of building a company." Read more.

Stuart Corr, executive director of Pumps & Pipes

For the eighteenth year in a row, the annual Pumps & Pipes event will showcase and explore convergence innovation and common technology themes across Houston’s three major industries. Image courtesy of Pumps & Pipes

Every year, Houston's legacy industries — energy, medicine, and aerospace — come together to share innovative ideas and collaborate on future opportunities. The annual Pumps & Pipes event will showcase and explore convergence innovation and common technology themes across Houston’s three major industries.

"With NASA in its backyard, the world’s largest medical center, and a reputation as the 'Energy Capital of the World,' Houston is uniquely positioned to lead in cross-industry convergence innovation and is reflected in the theme of this year’s event – Blueprint Houston: Converge and Innovate," Stuart Corr, executive director of Pumps & Pipes, writes in a guest column about the event. Read more.

Saniya Mansuri, health care consultant for BioPath @ TMC

The goal of the Texas Medical Center's BioPath program is to attract young people considering going into the trades to learn the skills to become biomanufacturing professionals. Photo via TMC

Houston is currently in need of biomanufacturing professionals to keep up with the ever-growing industry. That's what Saniya Mansuri, health care consultant for BioPath @ TMC, says.

“Houston has lost out on a big biopharmaceutical company. And when there was a feasibility study that was done, it was identified that one of the reasons that Houston wasn't chosen was the lack of a workforce and a lack of workforce development programs,” she explains.

Mansuri and the TMC Innovation team are doing just that with the introduction of the new program. She moved from Toronto in 2023. When she applied for a role at TMC Innovation, she was handpicked to help shepherd the BioPath program, thanks to her background that included starting a nonprofit for underserved youth in Canada. Read more.

German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

money moves

Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.