Innovation isn't always the safest field. Here's what to consider within incident reporting. Graphic by Miguel Tovar/University of Houston

Exploding refrigerator? Chemical splash on the face? These are not just personally devastating lab incidents, they are also expensive.

For instance, awhile back, the University of Hawaii faced a total $115,500 fine for 15 workplace safety violations after a laboratory explosion where a postdoctoral researcher lost one of her arms. Beryl Lieff Benderly wrote in Science that the accident “resulted from a static electricity charge that ignited a tank containing a highly flammable, pressurized mixture of hydrogen, oxygen and carbon dioxide.”

Referred to as “incidents,” they are defined by University of California Santa Barbara (UCSB) in this way: “An incident is an event that results in or causes injury or damage to someone or something, or an event that has the potential to result in or cause injury or damage.”

But when asked which incidents are reportable, the answer is uniform across all research universities: all incidents must be reported.

Incidentally...

There are websites dedicated to laboratory accidents, like this one at UCSB. It lists the two accidents mentioned in this blog’s first sentence. University of Michigan Environment, Health and Safety’s website said, “Being safe at the University of Michigan requires a positive safety culture where we learn from mistakes and near-misses in order to improve and prevent future occurrences. It is vital that you report all ‘incidents’ including near- misses, injuries resulting from your activities, non-compliance with safety and environmental rules, and general unsafe work conditions so that we can learn and grow.” Northwestern University’s website on Research Health and Safety said, “Always report ‘near-misses’ just as you would an incident that causes injury or harm to property.”

Near-missing

You may be asking, what constitutes a “near-miss”? At Western Kentucky University, for example: “A laboratory “near-miss” is an unplanned situation, where with minor changes to time or setting, could have easily resulted in damage or injury to person or property. A near-miss is characterized as having little, if any, immediate impact on individuals, processes, or the environment, but provides insight into accidents that could happen.” Laboratory near misses may cause chemical spills, explosions and bodily injury, but can be treated with first-aid.

Form finding

Most universities have a form to fill out if there is an incident that could have led to a severe injury or death. The form asks for a description of the incident and even asks, in some instances, “Why did it happen?” These should be made out comprehensively and quickly.

OSHA

The Occupational Safety and Health Administration (OSHA) has a reporting process, aside from what each university requires. They need information when you call. The OSHA website states: “Be prepared to supply: Business name; names of employees affected; location and time of the incident, brief description of the incident; contact person and phone number.”

There are even time limits for how quickly one must report a severe injury that requires an in-patient hospitalization, amputation or loss of an eye (24) or fatality.

(It’s eight hours.)

The fact that “losing an eye” is one of just four reasons to contact OSHA, you may wonder, “Are a lot of people blinded in the lab, often?” Also, “Where can I buy safety goggles?”

“Are a lot of people blinded in the lab, often? Also, where can I buy safety goggles?”

The big idea

There are many websites which detail lab disasters. Some are cautionary tales, some are avoidable situations. Just be sure to wear your Personal Protective Equipment (PPE) and be safe out there. Or rather, in there.

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This article originally appeared on the University of Houston's The Big Idea. Sarah Hill, the author of this piece, is the communications manager for the UH Division of Research.

Here's some advice for going green in the lab. Graphic by Miguel Tovar/University of Houston

Houston expert shares tips for shrinking your lab's carbon footprint

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Trying to make your lab greener? Here are some practical examples of how to reduce your lab's carbon footprint and increase sustainability. Since China stopped accepting certain types of plastic waste from the United States and Europe in 2017, the need to dispose of hundreds of single-use plastic vials and other materials (per researcher, each year!) has created an avalanche of waste.

The "single use" problem

COVID-19 has led to even more single-use plastics in labs – and in our everyday lives. The sheer number of gloves, testing kits and even masks we throw away is incredible. "The majority of masks are manufactured from long-lasting plastic materials, and if discarded can persist in the environment for decades to hundreds of years," wrote authors from the University of Portsmouth at the Conversation.com.

Reduce, reuse, recycle

Labs are full of other single-use plastics such as pipette tips, weighing boats, tubes, flasks, reagent bottles, cuvettes, and more. 'Reduce, reuse and recycle' is a fine mantra, but how do researchers cut down on plastics when the sterility of equipment is a concern?

According to the UK's Chemical and Engineering News magazine, "Different users have optimized washing protocols to get pipette tips clean enough for different lab techniques, including mass spectrometry or toxicology and immunology assays.

Earlier this year, for example, researchers at the National Institutes of Health's National Center for Advancing Translational Sciences found their washed pipettes gave the same results as new tips for preparing small-interfering-RNA screening libraries." Customers of Grenova, a lab equipment firm, have reported that some tips can reused 25-40 times.

Baby it's cold

In Nature, Jyoti Madhusoodanan wrote: "Scientists are increasingly aware of the disproportionate environmental footprint of their research. Academic research facilities consume three to six times as much energy as commercial buildings, much of that due to refrigeration and ventilation systems." The has led some third-party "green companies" employed by labs to hold entire conferences around ultra-low temperature freezers. In a feature advertisement in Nature Portfolio, a statistic read: "An average Ultra-Low Temperature freezer consumes as much energy as a single-family home (~20 kWh/day)."

Help for scientists

There are non-profits that will help you mitigate the amount of waste produced by your lab. One of these, My Green Lab, said on its website: "Run 'for scientists, by scientists,' we leverage our credibility and track record to develop standards, oversee their implementation, and inspire the many behavioral changes that are needed throughout the scientific community."

And it offers a free training course for "ambassadors" – those who would like to guide their lab toward sustainable practices.

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This article originally appeared on the University of Houston's The Big Idea. Sarah Hill, the author of this piece, is the communications manager for the UH Division of Research.

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Houston hospital names leading cancer scientist as new academic head

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Houston Methodist Academic Institute has named cancer clinician and scientist Dr. Jenny Chang as its new executive vice president, president, CEO, and chief academic officer.

Chang was selected following a national search and will succeed Dr. H. Dirk Sostman, who will retire in February after 20 years of leadership. Chang is the director of the Houston Methodist Dr. Mary and Ron Neal Cancer Center and the Emily Herrmann Presidential Distinguished Chair in Cancer Research. She has been with Houston Methodist for 15 years.

Over the last five years, Chang has served as the institute’s chief clinical science officer and is credited with strengthening cancer clinical trials. Her work has focused on therapy-resistant cancer stem cells and their treatment, particularly relating to breast cancer.

Her work has generated more than $35 million in funding for Houston Methodist from organizations like the National Institutes of Health and the National Cancer Institute, according to the health care system. In 2021, Dr. Mary Neal and her husband Ron Neal, whom the cancer center is now named after, donated $25 million to support her and her team’s research on advanced cancer therapy.

In her new role, Chang will work to expand clinical and translational research and education across Houston Methodist in digital health, robotics and bioengineered therapeutics.

“Dr. Chang’s dedication to Houston Methodist is unparalleled,” Dr. Marc L. Boom, Houston Methodist president and CEO, said in a news release. “She is committed to our mission and to helping our patients, and her clinical expertise, research innovation and health care leadership make her the ideal choice for leading our academic mission into an exciting new chapter.”

Chang is a member of the American Association of Cancer Research (AACR) Stand Up to Cancer Scientific Advisory Council. She earned her medical degree from Cambridge University in England and completed fellowship training in medical oncology at the Royal Marsden Hospital/Institute for Cancer Research. She earned her research doctorate from the University of London.

She is also a professor at Weill Cornell Medical School, which is affiliated with the Houston Methodist Academic Institute.

Texas A&M awarded $1.3M federal grant to develop clean energy tech from electronic waste

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Texas A&M University in College Station has received a nearly $1.3 million federal grant for development of clean energy technology.

The university will use the $1,280,553 grant from the U.S. Department of Energy to develop a cost-effective, sustainable method for extracting rare earth elements from electronic waste.

Rare earth elements (REEs) are a set of 17 metallic elements.

“REEs are essential components of more than 200 products, especially high-tech consumer products, such as cellular telephones, computer hard drives, electric and hybrid vehicles, and flat-screen monitors and televisions,” according to the Eos news website.

REEs also are found in defense equipment and technology such as electronic displays, guidance systems, lasers, and radar and sonar systems, says Eos.

The grant awarded to Texas A&M was among $17 million in DOE grants given to 14 projects that seek to accelerate innovation in the critical materials sector. The federal Energy Act of 2020 defines a critical material — such as aluminum, cobalt, copper, lithium, magnesium, nickel, and platinum — as a substance that faces a high risk of supply chain disruption and “serves an essential function” in the energy sector.

“DOE is helping reduce the nation’s dependence on foreign supply chains through innovative solutions that will tap domestic sources of the critical materials needed for next-generation technologies,” says U.S. Energy Secretary Jennifer Granholm. “These investments — part of our industrial strategy — will keep America’s growing manufacturing industry competitive while delivering economic benefits to communities nationwide.”

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This article originally appeared on EnergyCapital.

Biosciences startup becomes Texas' first decacorn after latest funding

A Dallas-based biosciences startup whose backers include millionaire investors from Austin and Dallas has reached decacorn status — a valuation of at least $10 billion — after hauling in a series C funding round of $200 million, the company announced this month. Colossal Biosciences is reportedly the first Texas startup to rise to the decacorn level.

Colossal, which specializes in genetic engineering technology designed to bring back or protect various species, received the $200 million from TWG Global, an investment conglomerate led by billionaire investors Mark Walter and Thomas Tull. Walter is part owner of Major League Baseball’s Los Angeles Dodgers, and Tull is part owner of the NFL’s Pittsburgh Steelers.

Among the projects Colossal is tackling is the resurrection of three extinct animals — the dodo bird, Tasmanian tiger and woolly mammoth — through the use of DNA and genomics.

The latest round of funding values Colossal at $10.2 billion. Since launching in 2021, the startup has raised $435 million in venture capital.

In addition to Walter and Tull, Colossal’s investors include prominent video game developer Richard Garriott of Austin and private equity veteran Victor Vescov of Dallas. The two millionaires are known for their exploits as undersea explorers and tourist astronauts.

Aside from Colossal’s ties to Dallas and Austin, the startup has a Houston connection.

The company teamed up with Baylor College of Medicine researcher Paul Ling to develop a vaccine for elephant endotheliotropic herpesvirus (EEHV), the deadliest disease among young elephants. In partnership with the Houston Zoo, Ling’s lab at the Baylor College of Medicine has set up a research program that focuses on diagnosing and treating EEHV, and on coming up with a vaccine to protect elephants against the disease. Ling and the BCMe are members of the North American EEHV Advisory Group.

Colossal operates research labs Dallas, Boston and Melbourne, Australia.

“Colossal is the leading company working at the intersection of AI, computational biology, and genetic engineering for both de-extinction and species preservation,” Walter, CEO of TWG Globa, said in a news release. “Colossal has assembled a world-class team that has already driven, in a short period of time, significant technology innovations and impact in advancing conservation, which is a core value of TWG Global.”

Well-known genetics researcher George Church, co-founder of Colossal, calls the startup “a revolutionary genetics company making science fiction into science fact.”

“We are creating the technology to build de-extinction science and scale conservation biology,” he added, “particularly for endangered and at-risk species.”