With three weeks left until game time, South by Southwest announced another long list of featured and keynote speakers. Photo via SXSW

Whether the return of South by Southwest (SXSW) in three weeks is putting butterflies in your tummy or sweat on your brow, we're in the home stretch. The newest announcement — another wave of featured speakers — does not say it's the final round, but time is running out to make adjustments before the start of the festival on March 10.

Previous announcements included keynote addresses from Patagonia CEO Ryan Gellert and team members who worked on the James Webb Space Telescope. There have also been two rounds of music showcase announcements, culminating in a list of nearly 500 performances.

The announcement on February 14 is heavy with big names including three entertainers presenting keynotes: actor, producer, and New York Times bestselling author Priyanka Chopra Jonas; Grammy Award-nominated singer-songwriter, producer, and author Margo Price; and Academy Award winner Tilda Swinton.

Two more newly announced keynote sessions come with longer descriptions: Chef José Andrés presents The Stories We Tell Can Change the World, and Bernard Sumner, Stephen Morris, and Gillian Gilbert of New Order appear in conversation with The Times rock & pop critic Will Hodgkinson.The former keynote tackles the responsibility of storytellers to address crises around the world, using Andrés' humanitarian group World Central Kitchen as a lens. The latter discusses the discography and history of the history-making band.

“Today's speaker announcement is a fantastic milestone for the 2023 event and spotlights five additional Keynotes and numerous Featured Speakers, including influential icons and up and coming innovators,” said Chief Programming Officer and Co-President Hugh Forrest. “We are extremely proud to have assembled a diverse, comprehensive conference program for SXSW, and we can’t wait to share it with our community in March.”

Organized into 25 programming tracks presented in a variety of session formats, SXSW celebrates the convergence of technology, film, television, and music. Tracks include civic engagement, climate change, design, film and TV, psychedelics, sports, travel, and more.

Just some featured speakers and sessions joining the 2023 lineup include:

  • Chair and CEO of General Motors Mary Barra with CEO, CTO, President, and co-founder of Cruise and co-founder of Twitch Kyle Vogt
  • Actress, philanthropist, entrepreneur, New York Times bestselling author, and co-founder of Hello Bello Kristen Bell, CEO of Hello Bello Erica Buxton, and actor, comedian, filmmaker, host of the podcast Armchair Expert, and co-founder of Hello Bello Dax Shepard
  • Chief Diversity Officer of TBWA\North America Aliah Berman with activist, advocate, author, and founder of the #MeToo Movement Tarana Burke
  • Founder and CEO of Joby Aviation Joe
  • Ben Bevirt with Chief Sustainability Officer at Delta Air Lines Pam Fletcher
  • Chief Digital and Commercial Officer at Unilever Conny Braams, President, Worldwide Advertising at Netflix Jeremi Gorman, founder and CEO of Media
  • Link Michael Kassan, and Senior Vice President and Chief Marketing and Communications Officer at Delta Air Lines Tim Mapes
  • Co-founder and President of OpenAI Greg Brockman with founder and CEO of Dot Dot Dot Media Laurie Segall
  • United States Secretary of Energy Jennifer M. Granholm
  • General Partner at Benchmark Bill Gurley with investor, New York Times bestselling author and host of the podcast The Tim Ferriss Show Tim Ferriss
  • The Art of Creating Influence 101 on navigating entertainment careers
  • The Blog Era: Hip-Hop's Wild Wild West on the influence of music bloggers
  • Daddy Issues in Film on fathers in film
  • Dateline 24/7: How the True Crime Powerhouse Became a Podcast Empire on a genre leader
  • Driving Personal Health Forward: The Role of Apple Watch and iPhone on digitally monitoring health at home
  • Evil Dead Rise: Flesh-Possessing Demons Come Home on the new Evil Dead film
  • An Inside Look at “Blindspotting” Season 2 with Rafael Casal and Daveed Diggs on the continuation of the series
  • Onyx Collective Presents “UnPrisoned” on a new Hulu series
  • The Kids Are (Not) Alright: Gun Violence Terrorizing Youth of America on activism and justice
  • Leguizamo Does America: Next Stop – Austin on the contributions of U.S. Latinos

For a full lineup and more information on featured sessions, visit SXSW.com.

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This article originally ran on CultureMap.

The grant program will fund and support diverse business owners. Pexels

Houston-based digital business resource launches minority-focused, celebrity-backed grant program

in the minority

A Houston-based startup that provides digital resources for entrepreneurs has introduced a new initiative to support minority-owned businesses — and the program has attracted some celebrity support.

Hello Alice has launched Business for All, which will provide funding and mentorship to small business owners. According to a news release, half of new businesses have a minority founder and these startups have only received 2 percent of annual venture capital.

"As entrepreneurs ourselves, my co-founder Elizabeth Gore and I know how valuable it is to have a network of people and resources in your corner when trying to turn a small business dream into reality," says founder and CEO of Hello Alice, Carolyn Rodz, in the release. "All businesses start small, and through Business for All, we will provide 100,000 owners with the opportunity to receive grants and mentorship through Hello Alice."

Business For All will distribute up to $200,000 in grants sized between $10,000 and $50,000. The startups will be selected through a nomination process and will focus on founders who are women, people of color, LGBTQ+ entrepreneurs, military affiliated business owners, and entrepreneurs with disabilities, according to the release.

Support for the program has come in the way of volunteer mentorship from celebs by the likes of Kristen Bell, Jean Case, Rebecca Minkoff, Phyllis Newhouse, Gwyneth Paltrow, Lisa Price, Zaw Thet, and more.

"I believe we should give every small business owner the tools they need to succeed. Business for All provides a combined voice, grants and mentorship to ensure success for every entrepreneur no matter their background," says Kristen Bell, entrepreneur, actress, and advocate, in the release.

Those entrepreneurs selected to receive grants will be invited to the inaugural Business for All Summit in fall 2020 for networking, mentorship, and business-focused programing.

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.