3 Houston innovators to know this week

who's who

This week's innovators to know roundup includes Kirsten Siebach of Rice University, Mike Francis of NanoTech Inc., and Kim Raath of Topl. Photos courtesy

Editor's note: In today's Monday roundup of Houston innovators, I'm introducing you to three innovators across industries — from space exploration to materials science.

Kirsten Siebach, assistant professor at Rice University

It's Kirsten Siebach's second Mars rover mission to work on. Photo courtesy of Rice University

Kirsten Siebach is getting ready for her Mars mission — one that keeps her firmly planted on Earth, but will allow her to search for ancient microbial life on the Red Planet nonetheless. The Rice University professor has again been selected by NASA to join a research team overseeing a rover that is currently en route to Mars.

"Because there is only one rover, the whole team at NASA has to agree about what to look at, or analyze, or where to drive on any given day," Siebach says in the release. "None of the rovers' actions are unilateral decisions. But it is a privilege to be part of the discussion and to get to argue for observations of rocks that will be important to our understanding of Mars for decades." Read more.

Mike Francis, co-founder of NanoTech Inc.

Mike Francis, co-founder of NanoTech, joins the Houston Innovators Podcast to discuss his plans to fireproof California. Photo courtesy of NanoTech

Mike Francis wants to fireproof the state of California. It's a lofty goal, but he has the means. His company, NanoTech Inc., has an innovative product that can insulate and fireproof materials, and, buoyed by a $5 million seed round, he's well on his way to being able to slowly but surely fireproof existing infrastructure in the West Coast.

"We're working with all of the major players in the state of California to not only fireproof the utility infrastructure, but eventually homes and businesses," Francis says on last week's episode of the Houston Innovators Podcast. "Our goal, if we're looking into the future, is to fireproof that state — and we're working with the right people and companies to make it happen." Read more and listen to the podcast.

Kim Raath, CEO of Topl

More and more consumers are expecting transparency from companies, and this Houston startup is on a mission to use blockchain to make businesses more transparent. Courtesy of Topl

Nowadays, consumers care about where their products come from — and if they exist due to a humanitarian or sustainable supply chain — and the onus is on businesses to increase transparency. That's where Topl, a Houston-based blockchain company, and its new partner Trackz, a Denver-based supply chain software company, come in.

"Topl and TrackX's solution will be a great option for companies having to comply with new regulations and compliance mandates," says Kim Raath, CEO of Topl. "Further, our joint solution allows users to visualize their supply chain data, monitor suppliers, and easily report the progress of ESG initiatives to all stakeholders."

A Rice University scientist will be working on the team for NASA's latest Mars rover. Image courtesy of NASA/JPL-Caltech

Rice scientist tapped by NASA for Mars mission

robo-naut

A Rice University Martian geologist has been chosen by NASA as one of the 13 scientists who will be working on a new Mars rover.

Perseverance, the rover that launched in July and is expected to land on Mars in February. It will be scouting for samples to bring back to study for ancient microbial life, and Kirsten Siebach — an assistant professor of Earth, Environmental and Planetary Sciences — will be among the researchers to work on the project. Her proposal was one of 119 submitted to NASA for funding, according to a Rice press release.

"Everybody selected to be on the team is expected to put some time into general operations as well as accomplishing their own research," she says in the release. "My co-investigators here at Rice and I will do research to understand the origin of the rocks Perseverance observes, and I will also participate in operating the rover."

It's Kirsten Siebach's second Mars rover mission to work on. Photo courtesy of Rice University

Perseverance is headed for Jezero Crater, a 28-mile-wide area that once hosted a lake and river delta where, according to scientists, microbial life may have existed over 3 billion years ago. Siebach is particularly excited hopefully find fossils existing in atmospheric carbon dioxide dissolved in water — which usually exists as limestone on Earth.

"There are huge packages of limestone all over Earth, but for some reason it's extremely rare on Mars," she says. "This particular landing site includes one of the few orbital detections of carbonate and it appears to have a couple of different units including carbonates within this lake deposit. The carbonates will be a highlight of we're looking for, but we're interested in basically all types of minerals."

Siebach is familiar with rovers — she was a member of the team for NASA's Curiosity rover, which has been exploring Mars since 2012. For this new rover, Siebach knows what to expect.

"Because there is only one rover, the whole team at NASA has to agree about what to look at, or analyze, or where to drive on any given day," Siebach says in the release. "None of the rovers' actions are unilateral decisions. But it is a privilege to be part of the discussion and to get to argue for observations of rocks that will be important to our understanding of Mars for decades."

Siebach and her team — which includes Rice data scientist Yueyang Jiang and mineralogist Gelu Costin — are planning to tap into computational and machine-learning methods to map out minerals and discover evidence for former life on Mars. They will also be using a Planetary Instrument for X-ray Lithochemistry, or PIXL, to analyze the materials.

The return mission isn't expected to return until the early 2030s, so it's a long game for the scientists. However, the samples have the potential to revolutionize what we know about life on Mars with more context than before.

"Occasionally, something hits Mars hard enough to knock a meteorite out, and it lands on Earth," she says in the release. "We have a few of those. But we've never been able to select where a sample came from and to understand its geologic context. So these samples will be revolutionary."

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UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.

New Texas Stock Exchange officially begins trading in Dallas

Welcome to Y'all Street

Two-step aside, New York Stock Exchange and Nasdaq. The Dallas-based Texas Stock Exchange, nicknamed Y’all Street, just kicked off live trading with five stocks — and lots of Lone Star ambition.

“The Texas Stock Exchange aims to revitalize competition for [stock] issuers, establish the premier venue for listings, and create a world-class trading platform for all market participants,” the exchange says in a fact sheet.

The exchange — whose Texas-influenced nickname is a nod to New York City’s Wall Street — has collected at least $275 million in investments. The roughly 90 financial backers of TXSE include Bank of America, BlackRock, Charles Schwab, Citadel Securities, Dell Family Office, Fortress, Goldman Sachs, and JPMorgan Chase.

Representatives of TXSE couldn’t be reached for comment. On its website, the exchange calls itself “the most well-capitalized equities exchange to ever be approved” by the U.S. Securities and Exchange Commission (SEC).

Not to be outdone, NYSE has launched Dallas-based NYSE Texas and Nasdaq has expanded its presence in Dallas.

Y’all Street adds to Dallas-Fort Worth’s rising status as a major hub for financial services, with The Wall Street Journal naming North Texas the country’s second biggest financial hub after New York City.

“A homegrown national exchange means more jobs, more investment, and more growth opportunities for businesses and communities across the Lone Star State,” Gabriela von zur Muehlen, senior vice president and chief policy officer at the Texas Association of Business, told The Texas Tribune.

Bulent Temel, an associate professor of practice in economics at the University of Texas at San Antonio, told Texas Standard that TXSE “is going to boost the credibility of the Texas economy.”

Texas’ estimated gross domestic product (GDP), a yardstick for the size of an economy, climbed to a record-setting $2.9 trillion in 2025, making it the state with the second highest GDP after California. DFW’s estimated GDP in 2023 stood at $744.6 billion, eclipsing the GDP of many countries.

“The center of gravity for American capitalism is now headquartered in the Boom Belt,” Abbott proclaimed in April, referring to an 11-state region (including Texas) in the South and Southeast that’s seeing tremendous economic and population growth. “The Texas Stock Exchange is the natural extension of that capitalism. It ensures that capital markets will reflect the quadrant that is driving American growth.”

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This article originally appeared on CultureMap.com.

Orion vehicle manager reflects on Artemis II, looks to 2028 moon mission

Q&A

Humanity is finally headed back to the moon after more than half a century. This year's launch of the Artemis II mission in the Orion spacecraft put four crew members in lunar orbit and tested the new ship developed by Lockheed Martin.

Everything went smoothly, safely returning astronauts home, but there is always room to improve. InnovationMap chatted via email with Orion vehicle manager Branelle Rodriguez, shortly after a talk at The Ion, for insight on how Orion might perform in the future as the next lunar landing approaches in early 2028.

InnovationMap: How satisfied are you with the way Orion operated on this past mission?

Branelle Rodriguez: Orion performed exceptionally well during Artemis II, successfully demonstrating critical spacecraft capabilities, including life support systems, displays and controls, and executing manual piloting operations. Artemis II brought humans back to the moon, achieving key exploration and scientific imagery, while validating systems essential for future Artemis missions.

IM: What is the most important thing you learned about improving Orion for the next mission?

BR: The Artemis II mission provided invaluable insights into crew operations and spacecraft performance in a deep-space environment. With every mission, NASA applies lessons learned to continuously improve Orion’s operations, validate design and ensure mission readiness. Artemis II offered our first opportunity to evaluate several new systems and gain a deeper understanding of what it is like for astronauts to live and work inside the spacecraft. The operational, technical and human factors data collected are being integrated across the program to refine future missions, reduce risk and enhance overall mission success.

IM: How has Orion helped the mission to explore space?

BR: Orion is one of NASA’s foundational elements for human deep space exploration—not only supporting the mission but serving as a core component of it. It is currently the only spacecraft capable of carrying crew on deep space missions and returning them safely to Earth from the high speeds required from the vicinity of the moon. No other spacecraft has the technology to endure the extremes that come with human deep-space travel, such as advanced environmental and life support, navigation, communications, radiation shielding, and the world’s largest ablative heat shield to protect the astronauts during reentry into Earth’s atmosphere. Orion has already taken astronauts to explore space farther than ever before—252,756 miles from Earth— and will carry crews to the moon on future missions to explore the lunar South Pole region. The astronauts’ observations, samples, and data collected on these future missions will expand our understanding of our solar system and home planet.

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This conversation has been edited for brevity and clarity.

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