Meet the new arrivals at Greentown Houston. Photo courtesy of Greentown Labs

Greentown Labs closed out the second quarter with the addition of 17 startups, and just over half are collaborating with the Houston location.

The technology represented by the new additions span the industries of energy, agriculture, and manufacturing, with a focus on carbon capture, electrical usage efficiency, and resource accessibility.

Carbon capture

Two of the newest Houston members, Capture6 and C-Quester, are also part of the Carbon2Value Initiative, a global partnership between the Greentown Labs, Urban Future Lab in New York, and Fraunhofer, headquartered in Michigan. C2V focuses on accelerating technology solutions that capture carbon dioxide for conversion into value-adding products and services.

Similar to the way a sponge is moistened and later wrung out, C-Quester pulls CO2 from flue gas into a temperature-sensitive material that can be heated later to release carbon, making the storage and transport of CO2 easier to manage.

Capture6 uses CO2 pulled from the atmosphere through their Direct Air Capture technology in combination with water treatment methodologies to remove excess salinity from saltwater and brine, resulting in greater freshwater recovery, usable elements for a variety of industries, and carbonates transformed into mineralized form to prevent continued carbon emissions.

Energy efficiency

The Helix MICRA filters created by Helix Earth Technologies can remove CO2 from power plants and other pollutants commonly encountered in the shipping industry. The filtering technology, initially developed for NASA, also dehumidifies air conditioning systems for more efficient energy use.

H2PRO uses its water-splitting technology, E-TAC, to produce green hydrogen in a two-step process that requires less energy to perform than the more common process of electrolysis with improved safety aspects.

Steam production and distribution get an upgrade with Imperium Technologies, the first electromechanical solution that enables previously unseen systems monitoring for reduction in greenhouse gas emissions by 20 percent, on average.

With a keen focus on predictive insights, eologix deploys smart sensors to give operators advance warning of situations that could cause rotor imbalances to keep wind turbines – and the energy they produce – optimized.

Resource accessibility

NW NA supports the goals of stability, predictability, and accessibility of electric-powered vehicle use with its high-power EV-charging station, mobile electricity storage units, and renewable energy measurement and forecasting tool.

From the Metaversity under development, to its oil and gas line leak detection systems, Kauel goes all-in on AI for its clients, even helping children with kinesthetic rehabilitation through augmented and virtual reality programs.

Finally, SkyH2O brings fresh, clean water to areas with limited access to existing infrastructure or natural water resources for commercial, military, and industrial use.

Another eight startups join the cohort named above as members of the Greentown Labs Boston location: Capro-X, Carbon2Stone, Cottage, Dioxycle, enaDyne, Global Algae Innovations, Terrafixing, and Thola.

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This article originally ran on EnergyCapital.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.