Through the Houston-based Muvve app, fitness fans can meet each other on the app or at curated events around town. Courtesy of Muvve

When Avi Ravishankar decided to train for a marathon in high school, he wanted to find a training buddy. He got lucky, and one found him: his classmate, Julian Se, took on the task.

"Julian decided he was going to train with me — he's a strong personality," Ravishankar says. "We started training, and to this day, we just became best friends from there."

Usually, finding fitness friends and training buddies isn't that easy — especially in a huge, spread out city of Houston. Ravishankar and Se turned their friendship into a business partnership to solve this problem. Houston-based Muvve is a mobile app that's mission is to connect fellow fitness enthusiasts across the city. The two came up with the idea as a way to merge their passions.

"The only idea we had was we wanted to have a startup with running," Ravishankar, co-founder of Muvve, says. "We loved running and tech, so we just wanted to find a way to bridge the gap there."

Ravishankar, a Rice University alumnus, says he took his idea to Owl Spark, an early stage accelerator on campus, and they just started asking people about their pain points when it came to working out.

"The big two things that we found were accountability and motivation," he says. "Out of 100 people, I would say all 100 people said that."

Ravishankar, who worked for six years in engineering at Oxy, says that these pain points are actually pretty inherent to individual sports.

"Intrinsic motivation is hard to find, especially in individual sports, like running, cycling, or yoga," he says. "Whereas, in team sports, like basketball or volleyball, you have the team to train with and motivate you."

The app, which launched in May of 2018, acts like a network for fitness lovers — just like a dating app would connect potential romantic partners. Dating apps, actually, were a big influence on Ravishankar, he says.

"I fell in love with dating apps. It was this mind-blowing idea for me of how many people you can connect with — even if it's not for dating," he says. "The amount of people I have met just through technology always blows my mind. There's so much power in it."

Through his experience as an instructor at Black Swan Yoga, Ravishankar also realized boutique fitness studios needed a place to market their events to a wider audience. This gave Ravishankar an idea of a way to bridge the gap between different fitness studios around town via the app.

"For us the goal is to have all of these events and activities to go and meet like-minded people," he says.

Muvve's goal is to have these managed market events that are curated to ensure quality, rather than the hit or miss aspect of existing platforms.

"For me the curation aspect makes for a better experience," Ravishankar says.

Now, Muvve is focused on growing its user base from 4,500 to 10,000 users by summer. Simultaneously, the company is hoping to launch its first seed round of funding, and then using its funds and its network to launch into Austin by summer.

Ravishankar says finding potential investors has been the most challenging aspect.

"There's no money in Houston for a fitness tech startup," he says. "That space isn't really respected. For me, it's kind of a trickling effect. If there's no money in it, there's no one really to help you because they don't have a vested interest."

While funding has been daunting, Ravishankar says he's had some success in hiring out his team of developers, despite the uphill battle of hiring tech talent in Houston.

"There's hidden talent, but it's not obvious talent," Ravishankar says. "I think that people get discouraged by hiring in Houston because of that."


Muvve is harnessing the power of social media and digital networks to bridge the gap between fitness lovers across the city. Courtesy of Muvve

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.