Houston entrepreneurial community builder teams up with startup to provide AI-powered founder tools

howdy, partner

The Cannon, a coworking community with locations across Houston, and nstAI, a newly launched suite of services for founders, announced a new partnership. Photo courtesy of The Cannon

A new Houston company has launched to provide a new platform of resources for entrepreneurs powered by artificial intelligence, and the new business already has its first partner.

The Cannon, a coworking community with locations across Houston, and nstAI, a newly launched suite of services for founders, announced a new partnership.

“The opportunity for The Cannon to partner with nstAI to bring a value-driven service offering to growth stage startup organizations is huge for our community. We are constantly looking for areas where we can support every startup, no matter where they are in their journey,” Jon Lambert, The Cannon’s CEO, says in a statement. “The nstAI offering, delivered through The Cannon's platform, will bring tremendous value to emerging companies who are in perhaps the most critical stage of their journey, garnering true market presence and customer share.”

Founded by seasoned entrepreneurs, nstAI's support is targeted aid startup founders during the early phases of business development, including securing non-dilutive funding, creating pitch decks and other materials, as well as making meaningful connections with mentors and potential customers.

"The journey from post-Seed funding to Series B funding is often one of the most challenging phases for founders," John Cooper, a founding partner at nstAI, adds. "We've designed nstAI to be a trusted resource in that process, offering hands-on guidance, leveraging AI-powered tools, and providing access to an unmatched global network of experts and investors."

The nstAI platform will be integrated into The Cannon's digital platform, Cannon Connect, for its members.

"nstAI is more than just a service provider; we're a community of successful entrepreneurs dedicated to supporting each other's growth and success," Mark Voytek, founding partner at nstAI, says in the release.

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This week's roundup of Houston innovators includes Jon Lambert of The Cannon, Ken Cowan of Enchanted Rock, and Richard Wilson of the University of Houston. Photos courtesy

3 Houston innovators to know this week

who's who

Editor's note: Every week, I introduce you to a handful of Houston innovators to know recently making headlines with news of innovative technology, investment activity, and more. This week's batch includes a podcast with the CEO of a community-focused coworking space, a professor joining a major health care research project, and a guest columnist with advice on navigating the energy transition.

Jon Lambert, CEO of The Cannon

Jon Lambert, CEO of The Cannon, joins the Houston Innovators Podcast to discuss the growth of The Cannon, including its newest location. Photo courtesy of The Cannon

For the past five years as CEO, Jon Lambert has faced some challenges leading The Cannon — from navigating a global pandemic to the subsequent evolved real estate market. But now, the coworking and community building company is poised for even more growth — especially with its ninth location opening up this month — thanks to its community-driven mission.

The Cannon Memorial opens its doors on Monday, May 13, with a week of free coworking and events. And while the new space, developed in partnership with MetroNational, is open for leasing, Lambert says on the Houston Innovators Podcast the first and foremost, The Cannon is a community.

"The Cannon wasn't created as a real estate play — we got into coworking because as we started supporting the community and asking the question of, 'what can we do for you?,' one of the highlights was, 'hey, we need space to work,'" he says on the show. "For us, we were going to provide space because that's one of the key needs of this community.

"Our measurement of success is not the buildings we have or the occupancy even — it's what's the success of the companies that are part of the community," he continues. Click here to read more.


Ken Cowan, senior vice president of Enchanted Rock

Ken Cowan writes a guest column for InnovationMap. Photo courtesy

As senior vice president of Enchanted Rock, a Houston-based provider of microgrid technology, Ken Cowan has seen how energy resilience has emerged as a key strategy for businesses across industries, as he writes in a guest column for InnovationMap.

"Executives must recognize the strategic imperative of investing in resilient energy infrastructure like microgrid systems, which can provide a competitive advantage against organizations that do not have similar measures in place," he writes. "In doing so, they can navigate uncertainty with confidence, set their business up for future success, and emerge stronger and more resilient than ever before."

In the piece, he explores the value proposition and other benefits to making these changes. Click here to read more.

Richard Willson, Huffington-Woestemeyer Professor of chemical and biomolecular engineering at the University of Houston

Richard Willson (center) and his team are working to develop a mix-and-read antibody measurement system that uses fluorescent materials to determine the amount of antibody present in a sample. Photo via UH.edu

An engineering project at the University of Houston has been selected to join a $10 million effort to bring biopharmaceutical manufacturing into the future. The National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL) chose the lab of Richard Willson, Huffington-Woestemeyer Professor of chemical and biomolecular engineering at UH, as one of eight development projects that it will fund.

Willson and his team are working to develop a mix-and-read antibody measurement system that uses fluorescent materials to determine the amount of antibody present in a sample. The funding for this project is $200,000. This is the first grant UH has received from NIIMBL.

“In the course of the manufacturing processes, it's important to know the concentration of antibody in your sample and this measurement needs to be made many times in a typical manufacturing process,” said Willson in a press release. In the realm of fluorescents, he is also working to pioneer the use of glow sticks to detect biothreats for the U.S. Navy. His discoveries include a fluorescent material that emits one color of light when excited with another color of light. Click here to read more.

Jon Lambert, CEO of The Cannon, joins the Houston Innovators Podcast to discuss the growth of The Cannon, including its newest location. Photo courtesy of The Cannon

How this community-focused coworking concept plans to continue growth around Houston and beyond

HOUSTON INNOVATORS PODCAST EPISODE 235

For the past five years as CEO, Jon Lambert has faced some challenges leading The Cannon — from navigating a global pandemic to the subsequent evolved real estate market. But now, the coworking and community building company is poised for even more growth — especially with its ninth location opening up this month — thanks to its community-driven mission.

The Cannon Memorial opens its doors on Monday, May 13, with a week of free coworking and events. And while the new space, developed in partnership with MetroNational, is open for leasing, Lambert says on the Houston Innovators Podcast the first and foremost, The Cannon is a community.

"The Cannon wasn't created as a real estate play — we got into coworking because as we started supporting the community and asking the question of, 'what can we do for you?,' one of the highlights was, 'hey, we need space to work,'" he says on the show. "For us, we were going to provide space because that's one of the key needs of this community.

"Our measurement of success is not the buildings we have or the occupancy even — it's what's the success of the companies that are part of the community," he continues.


Lambert shares more about The Cannon's community-focused growth by giving Fulshear as an example. The new community west of Houston isn't currently working on developing a coworking facility yet, but from a programming and digital perspective, The Cannon has established a presence.

"The first phase of the project is to just mobilize the startup and early-stage business community in Fulshear and see what kind of energy and vibe we can create there and connect them to The Cannon's resources and community," Lambert says. "That's our big-picture vision. We can build a new node of community — through a new real estate opportunity, economic development or university relationship — that's beneficial in itself, but that node gets connected to everything else."

With a recent acquisition, The Cannon has further grown its ability to engage its communities digitally. In February, Village Insights, a community management platform, was acquired by The Cannon, onboarding its core employees and further integrating the platform it was already using.

When it comes to its next expansion, The Cannon has a lot of opportunity both around and beyond Houston, Lambert says.

"Any direction is an opportunity and possibility," he says. "I would project that by the end of the year, we'll probably be having another conversation about what The Cannon's doing in other cities as well — for the benefit of The Cannon Community in Houston."

Introducing — The Cannon Memorial, which is opening its doors on Monday, May 13. Photo courtesy of The Cannon

Photos: The Cannon announces opening of newest location in Memorial

ready to cowork

The Cannon is gearing up to open its latest location featuring coworking and community events and programming.

The coworking concept, which announced The Cannon Memorial earlier this year, will officially open the new location on Monday, May 13, with a full week of community-focused events. The new location was developed in partnership with MetroNational, the real estate developer behind 300-acre mixed-use development in West Houston.

“MetroNational has long been recognized for offering exceptionally located, high quality, well amenitized office space,” says Anne Marie Ratliff, vice president of Asset Management at MetroNational, in a news release. “The Cannon Memorial diversifies our existing office portfolio to provide flexible space solutions for the evolving needs of the business community.”

The Cannon Memorial has 39 furnished offices, flex user space, dedicated seating, lockable storage, a fully stocked kitchen with complimentary coffee, and five bookable meeting rooms. Members will also receive 24/7-access to the facilities and free parking in the attached garage.

Beginning May 13 and running through May 17, potential members can try out the coworking space for free, as well as attend daily events:

  • Monday, May 13: Coffee & Community (2 to 3 pm)
  • Tuesday, May 14: Community Lunch (11:30 am to 12:30 pm)
  • Wednesday, May 15: Open House and Happy Hour (4 – 6 pm)
  • Thursday, May 16: Therapeutic Thursday with 15-minute massages (noon to 2 pm)
  • Friday, May 17: Cowboy Breakfast (9 to 10 am)

"As we open the doors to our next innovation focused workspace, we couldn't be more thrilled to share this moment with our community," says Jon Lambert, CEO of The Cannon. "This week marks not just the inauguration of a new physical space, but the realization of a shared vision and the culmination of an exceptional partnership with our partners at MetroNational. More than just a space, The Cannon Memorial will be an environment where innovation thrives.”

The Cannon Memorial has 39 furnished offices.

  

Photo courtesy of The Cannon

With seven locations across the Houston area, The Cannon's digital technology allows its members a streamlined connection. Photo courtesy of The Cannon

Houston coworking company acquires digital community platform

M&A moves

After collaborating over the years, The Cannon has acquired a Houston startup's digital platform technology to become a "physical-digital hybrid" community.

Village Insights, a Houston startup, worked with The Cannon to create and launch its digital community platform Cannon Connect. Now, The Cannon has officially acquired the business. The terms of the deal were not disclosed.

“The combined commitment to support innovation communities—large and small—is evident,” Andrew Ramirez, who served as CEO for Village Insights ahead of the acquisition, says in a news release. “Village Insights and The Cannon merged to align efforts and cultivate local, regional and global innovation communities. Combining our value propositions represents a significant leap forward for the populations that we serve.”

With seven locations across the Houston area, The Cannon's digital technology allows its members a streamlined connection.

“The Cannon’s hub network stretches from The Woodlands to Galveston and across the 13-county region, with a membership base of more than 900 companies and 3,000 employees,” Jon Lambert, CEO of The Cannon, adds. “The digital extension of our physical footprint brings comprehensive innovation and business development support to communities that need it the most. Cannon Connect’s virtual- connection capabilities stand to remarkably expand our universe of ecosystem opportunities.”

Village Insights was founded in 2020. According to the release, the acquisition began in December, and members of the Village Insights core leadership team have rolled onto new roles at The Cannon.

“The integration of a world-class onsite member experience and Cannon Connect’s superior virtual resource network creates a seamless, streamlined environment for member organizations,” Clemmie Martin, The Cannon’s newly appointed chief of staff, says in the release. “Cannon Connect and this acquisition have paved new pathways to access and success for all.”

The Cannon is opening a new location just down the road from its headquarters. Photo courtesy of The Cannon

Houston coworking concept expands with new location

coming soon

The Cannon has announced its latest coworking location, and it's not too far from where the company's original facility launched.

The Cannon Memorial is expected to open this spring in Two Memorial City Plaza (820 Gessner) within MetroNational's Memorial City, a 265-acre planned development in west Houston. The coworking concept will take up one floor with 21,960 square feet of space.

"We are delighted to unveil The Cannon Memorial as a pivotal addition to Houston's dynamic business landscape," Jon Lambert, CEO of The Cannon, says in a news release. "Our expansion into Two Memorial City Plaza aligns seamlessly with our mission to cultivate innovation, collaboration, and success within the business community. We eagerly anticipate welcoming entrepreneurs and professionals to experience the unparalleled environment we've created."

The new location is less than three miles from The Cannon West Houston (1334 Brittmoore Rd) and will feature:

  • 38 private office spaces
  • accomodations for over 60 flex users
  • 24/7 access for members
  • free covered parking in the attached garage
  • programmed events, workshops, and networking sessions

“MetroNational is thrilled that The Cannon Memorial is opening and is another exciting milestone in our continued commitment to constantly elevate and enhance the services and experiences at Memorial City,” Anne Marie Ratliff, vice president of Asset Management at MetroNational, says in the release. “This partnership represents not just a collaboration but a testament to our dedication to staying at the forefront of innovation.”

The Cannon — founded in 2017 by Lawson Gow, the son of David Gow, founder of InnovationMap's parent company, Gow Media — has a presence in seven of Houston's regions, including west Houston, downtown, uptown, Fish Creek, The Woodlands, Pearland, and Galveston.

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

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