Tim Boire, CEO and co-founder of VenoStent, shares his company's roadmap on this week's episode of the Houston Innovators Podcast. Photo via LinkedIn

Commercializing a health tech innovation is a long game — fraught with regulatory obstacles, cyclical rounds of funding, and continuous improvement — all fueled by the desire to enhance treatment and save lives.

That's Tim Boire's plan. And it's a thorough one at that. On this week's episode of the Houston Innovators Podcast, Boire — president and CEO of VenoStent, a medical device startup that’s designing a unique material for hemodialysis patients — shares his roadmap for his company.

"We believe we can be pioneers of a paradigm shift in vascular surgery — to not just treat problems after they've already occurred, but actually prevent them from occurring in the first place," he says in the episode.

VenoStent's most recent hurdle cleared is closing a $16 million series A round of venture funding. Two Charleston, South Carolina-based firms — Good Growth Capital and IAG Capital Partners — led the round. The TMC Venture Fund also contributed.

Now, VenoStent is headed for a 200-patient trial in the United States, with an ultimate goal of product launch in 2026. The company's unique medical device is a bioabsorbable wrap that reduces vein collapse by providing mechanical support and promoting outward vein growth.

Boire had the idea for VenoStend when he was completing his PhD at Vanderbilt University. He completed the program, and then joined the HealthWildcatters accelerator in 2017 in Dallas. After that, Boire and his co-founder, Geoff Lucks, decided to take the leap and move to Houston to join JLABS at TMC. The rest, as they say, is history.

“Houston’s been a great place to hire,” Boire says. “We've been I think very fortunate to find our employees who are stellar, true believers in the technology — amazing engineers, and amazing people.”

And, of course, Boire has a plan to continue this hiring success. He says the goal is to grow to a team of 16 by the end of the year. Marketing and sales roles will likely be filled in 2025 ahead of product launch.

“When we think about what our mission is at VenoStent, it’s to ultimately improve patient care — and we are very passionate about this specific problem that patients experience and go through,” Boire says.

“That's what drives everything we're doing as a company to improve quality and length of life for patients who have chronic kidney disease that progresses to a point where they need dialysis to sustain life," he continues. "We believe that we can become the standard care for vascular surgery starting with hemodialysis access."

As VenoStent's trials and growth goes according to plan, Boire says this product can be used for other implications.

Boire shares more on his grand plan, plus how he weathered the storm that is fundraising at a time where so much venture capital activity has slowed. Listen to the interview here — or wherever you stream your podcasts — and subscribe for weekly episodes.

7 Hills Pharma, an innovative immunotherapy company, was awarded a $13.5 million grant from the Cancer Prevention and Research Institute of Texas. Photo via Getty Images

Houston immunotherapy company to use $13.5M grant to further develop cancer treatments

future of pharma

Between Bangalore and Chennai in the Indian state of Andhra Pradesh, you’ll find the town of Tirupati. It’s home to seven peaks that host a Hindu temple complex devoted to a form of Vishnu, Venkateshvara. It is also the region from which Upendra Marathi originally hails. It’s where his father, and many other family members, attended medical school.

“My father’s first job was to take care of the pilgrims,” recalls Marathi.

It's only natural that his groundbreaking Houston company would be named 7 Hills Pharma.

“That sort of selflessness and giving back, I wanted to embody it in the name of the company,” Marathi says.

Now, 7 Hills Pharma is announcing that last month, it was awarded a $13.5 million grant from the Cancer Prevention and Research Institute of Texas (CPRIT). That’s on top of more than $13 million in NIH grants, making the company the second largest recipient of SBIR/STTR grants in Texas.

Launched in 2016, 7 Hills Pharma is working to develop drugs that can overcome the all-too-common problem of immunotherapy resistance. Thanks to the Nobel Prize-winning work of Jim Allison in the realm of immuno-oncology, the field was “very hot” at the time, says Marathi, particularly in Houston.

So what has 7 Hills developed? Oral small molecules that activate integrins — the receptors that allow cells to bind to one another — allowing for the cell-to-cell interactions that create a successful immune response to immune checkpoint inhibitors such as Yervoy. In other words, they have created capsules that increase the effectiveness of drugs that allow the body’s own immune response to fight cancers.

But that’s not all. Tests have shown that the same discovery, called alintegimod, can also augment the effectiveness of vaccines. The pill, which co-founder and co-inventor Peter Vanderslice calls “a beautiful way to amplify the vaccines,” can potentially be applied to anything from influenza to coronavirus.

Their greatest challenge, says Vanderslice, is the very fact that the technology is so novel.

“Most large pharmas are very risk averse,” he explains. “They only want to do ‘me-too’ kinds of drugs.”

7 Hills Pharma is the third company Marathi, both a PhD and an MBA, has helped to found based on technology he co-invented. Vanderslice is director of the molecular cardiology research laboratories at The Texas Heart Institute.

“It’s very much a homegrown company,” Marathi says.

And a small one, at least for now. Working out of JLabs@TMC, the full-time team is currently just Marathi and Siddhartha De, the senior director of development. Marathi convinced De to transplant himself and his family from India for the purpose of assisting 7 Hills with preparing its drugs for clinical readiness.

The CPRIT funds will allow 7 Hills Pharma to hire several long-time team members full-time and with benefits.

“The bringing of talent and bringing of technology to TMC and what was born at Texas Heart Institute is rather remarkable,” says Rob Bent, the company’s director of operations.

The next step for 7 Hills Pharma is a Phase Ib/IIa clinical trial in patients with treatment-resistant solid tumors. And the team just finalized the deck that will help raise another $10 million to $250 million in the company’s series A. And hopefully sooner rather than later, a new set of medical pilgrims will be thanking 7 Hill Pharma for its care.

It's a busy month in Houston. Luis Alvarez/Getty Images

10+ can't-miss Houston business and innovation events for March

Where to be

Editor's note: SXSW has been canceled due to the coronavirus since the publishing on this events roundup. The original version of this article is below.

March is a busy month for Houston in general — but especially when it comes to innovation. The inaugural Houston Tech Rodeo starts out the month and the Rice Business Plan Competition closes out March in a few weeks — and the interactive weekend at SXSW falls right in the middle of the month for those planning the trip to Austin.

But for the Houston innovators in the energy industry, March got a little less busy when CERAWeek by IHS Markit was canceled due to the growing threat of the coronavirus, or COVID19.

Should any other events below have that same fate, this article will be updated.

March 2-6 — Houston Tech Rodeo

A week full of events, the Tech Rodeo is made up of over 30 innovation events across Houston. These are InnovationMap's picks for what to attend during the week. For a complete list of the events (most of which are free), head to the website.

Details: The event is from Monday, March 2, to Friday, March 6 across Houston. Learn more.

March 5 — Space Center Houston's Thought Leader Series: Designing for Human Performance

Learn how human factors engineering relates to spacecraft and spacesuit design while celebrating Women's History Month and the 20th anniversary of the International Space Station. Speakers include Celena Dopart, human factors engineer for Starliner at Boeing, and Katie Spira, NASA flight controller.

Details: The event is at 7 pm on Thursday, March 5, at Space Center Houston (1601 E NASA Pkwy). Learn more.

March 6 — Premier Talks: Women in Innovation & Technology 

Join this panel of accomplished women as they discuss the importance of being a woman in the current workforce and leading among your peers. Be empowered to self-evaluate, inspire those around you, and raise the bar on your professional goals. Discuss the challenges women face in a male dominated technology workforce and why it is important to take the limits off of your thinking.

Details: The event is from 9:15 to 11 am on Friday, March 6, at GA Houston (1301 Fannin St, Floor 21). Learn more.

March 6 — The Greater Houston Partnership’s Rise to the Top

Celebrating International Women's Day, the Greater Houston Partnership and the Partnership's Women's Business Alliance brings the Rise to the Top event. Expect a keynote address from Gretchen Watkins, president atShell Oil Company and executive vice president at Global Unconventionals, Shell Oil Company, and candid conversations from a panel of female executives discussing the challenges and triumphs of succeeding as a woman in today's business environment.

Details: The event is from 10:30 am to 1:30 pm on Friday, March 6, at Hilton Americas (1600 Lamar St.). Learn more.

March 10 — Equinor & Techstars Energy Accelerator Meet & Greet

If you're an energy-focused startup, don't miss this info session with the Equinor & Techstars Energy Accelerator, which is visiting Houston and looking for the 10 best energy companies for its next cohort.

Details: The event is from 6 to 9 pm on Monday, March 10, at The Ion (1301 Fannin Street, Suite 2440). Learn more.

March 10-11 — Energy 2.0: Equality, Environment, and the New Economy

Join over 100,000 people taking part in Energy 2.0 2020; an innovative experience that addresses new frontiers in the energy industry where business, workforce, environment, innovation, and policy intersect. Spread across multiple locations and continents, corporate watch sites around the globe, and simulcast online, Energy 2.0 brings energy professionals and a diverse mix of experts across various disciplines together for learning and networking opportunities.

Details: The event is from Monday, March 10, to Tuesday, March 11, online and at The Westin Houston, Memorial City (945 Gessner Rd.). Learn more.

March 12 — Lunch n' Learn: In Today's Market - Do Patents Even Matter?

Inventors and business professionals are asked to review the claims of their patent application before it is filed. This step is THE critical step that is supposed to ensure that the claims will protect their invention. The decision you make here determines if you will be part of the 97 percent of all patents that never recoup the cost of filing them.

Details: The event is from noon to 1:30 pm on Wednesday, March 12, at The Ion (1301 Fannin Street, Suite 2440). Learn more.

March 19 — Science First: How 3D Printing is Reshaping the Future of Healthcare

Technology is evolving faster than ever – and advancements in 3D printing could revolutionize the delivery of healthcare products and solutions to change the trajectory of health for humanity.

Details: The event is from 11:30 am to 2 pm on Wednesday, March 19, at JLABS @ TMC (2450 Holcombe Blvd.). Learn more.

March 24 — How to Form a Micro VC Fund Workshop at Mercury Fund

Welcoming all angels, previous founders, MBA students, aspiring and current venture capitalists that are interested in learning more about the basic essentials for starting a small venture fund. Speakers are Blair Garrou of Mercury Fund and Justin LaPoten of BADR Investments.

Details: The event is from 10 to 11 am on Tuesday, March 24, at Mercury Fund (3737 Buffalo Speedway, #Suite 1750). Learn more.

March 25 — 2020 H. Albert Napier Rice Launch Challenge - Startup Competition

The H. Albert Napier Rice Launch Challenge Startup Competition is Rice's newest entrepreneurship competition, awarding over $60,000 in prize money to Rice-affiliated teams. Students and alumni enter business ideas (high growth ventures or small business ideas) to compete.

Details: The event is from 6 to 9 pm on Wednesday, March 25, at Liu Idea Lab For Innovation & Entrepreneurship (Rice University - Cambridge Office Building). Learn more.

March 26 — T3CH Workshop: Grow With Google "Using Data to Drive Business Growth"

In this T3CH workshop, you'll learn best practices on data-driven decision making; and get practical guidance on how to find and analyze trends regarding online customer engagement with your business, so you can turn those insights into well-informed, actionable decisions.

Details: The event is from noon to 1 pm on Thursday, March 26, at Impact Hub Houston @ The Cannon Post Oak (675 Bering Drive, #200). Learn more.

March 26-28 — Rice Business Plan Competition

The event — dubbed the "world's richest and largest student startup competition" — begins later this month. The Rice Business Plan Competition will host 42 student teams from all over the world. The three-day contest consists of pitches, judging, and a closing banquet where the winners are revealed.

Details: The event is from Thursday, March 26, to Saturday, March 28, at Rice University and the Hilton Americas. Learn more.

Check out these panels, networking meetups, and more. Getty Images

10+ can't-miss Houston business and innovation events for February

Where to be

Despite the short month, Houston will play host to tons of innovation networking, panel, and meetup events throughout the month of February. And, it's a leap year, so take that as an opportunity to jump into the startup ecosystim in town.

If you know of innovation-focused events for this month or next, email me at natalie@innovationmap.com with the details and subscribe to our daily newsletter that sends fresh stories straight to your inboxes every morning.

February 4 — How AI Can Boost Your Business with Ryan Shirzadi of Tekrevol

How can artificial intelligence help grow your business? Specifically, Ryan Shirzadi of Tekrevol will be covering the social impacts, industries affected, why you need an AI strategy, and how AI can help small businesses grow. Networking will follow the discussion and pizza will be provided by Tekrevol.

Details: The event is from 6 to 7:30 pm on Tuesday, February 4, at Station Houston (1301 Fannin Street, Suite 2440). Learn more.

February 5 — Meet and Greet with Pat Matthews, CEO & Founder of Active Capital

Meet Active Capital's founder and CEO, Pat Matthews. Rakesh Agrawal, founder and CEO of Snapstream, will interview Matthews followed up by an open Q&A and conversation with the audience.

Details: The event is from 5:30 to 6:45 pm on Wednesday, February 5, at WeWork (708 Main Street, 3rd Floor). Learn more.

February 5 — Houston Social Entrepreneurship Meetup

The meetup brings together like-minded individuals from the nonprofit, social enterprise, impact investing, technology and many other fields to understand the concept of social entrepreneurship and be inspired to find new ways to tackle local social issues. At each meetup, you'll get an intro to social entrepreneurship, hear from a social entrepreneur in Houston, and network with other changemakers from across the entrepreneur ecosystem.

Details: The event is from 5:30 to 7:30 pm on Wednesday, February 5, at Impact Hub Houston @ The Cannon Downtown (1801 Main St., 13th Floor). Learn more.

February 6 — Fail Forward presented by Frost Bank

Join BakerRipley and Frost Bank for an evening of #FailForward fun and get real, behind-the-scenes stories straight from entrepreneurs on the challenges they faced trying to access and raise funding for their small business or startups.

Details: The event is from 6 to 8 pm on Thursday, February 6, at BakerRipley Center (4450 Harrisburg Blvd.). Learn more.

February 12 — The Impact of AI on Automation and the Future of the Workforce

Technology and innovation are rapidly changing how we do and think about work. This panel event seeks to bring together respected leaders in the corporate and entrepreneurial worlds to have meaningful conversations on AI, automation and the future of workforce.

Details: The event is from 6:30 to 9 pm on Wednesday, February 12, at GA Houston (1301 Fannin St, Floor 21). Learn more.

February 13 — Female Founders Breakfast with Baker Botts and The Artemis Fund

Baker Botts L.L.P. and The Artemis Fund have come together to bring you a breakfast panel discussion on how a good corporate governance system and a little corporate housekeeping can avoid larger messes down the road.

Details: The event is from 8:30 to 10:30 am on Thursday, February 13, at Baker Botts (910 Louisiana St., 32nd Floor). Learn more.

February 18 — How She Got There: Women Leaders in Tech

Join General Assembly for an evening good conversation with a panel of females in tech. These inspirational women will share their stories on how they got to where they are today and share their insights into being a woman in business and tech.

Details: The event is from 6:30 to 9 pm on Tuesday, February 18, at GA Houston (1301 Fannin St, Floor 21). Learn more.

February 19 — Houston Angel Summit

Join the Houston Angel Network for its bi-annual summit. Attendees will learn the basics of angel investing as well as hear from experts on the topics of term sheets and tax implication of early stage investing. This event is open to accredited investors, HAN members and individuals from our partnership organizations. The price of attendance — $100 — will be applied to annual membership if attendees decide to join the Houston Angel Network.

Details: The event is from 9 am to 3 pm on Wednesday, February 19, at Liu Idea Lab for Innovation and Entrepreneurship (Cambridge Building at Rice University). Learn more.

February 20 — The Five W's of Holding Your First, First-in-Human Trial

Who, what, when, where and why to hold your first, first-in-human clinical trial? JLABS has tapped into experts in the field from Johnson & Johnson, CROs and agencies to help you answer these questions and more.

Details: The event is from 11:30 am to 2 pm on Thursday, February 20, at JLABS @ TMC (2450 Holcombe Blvd.). Learn more.

February 20 — Bunker Brews Houston: How to be Mentored in Your Business

Lots of entrepreneurs fail to seek out mentors, and struggle in silence and isolation because of it. Some will find great mentors, but fail to recognize the unspoken rules of the road to acquire, activate, and maintain a mentor-mentee relationship. Hear from some great local mentors of business owners.

Details: The event is from 6 to 8 pm on Thursday, February 20, at MassChallenge (1313 Main St., Suite 210). Learn more.

February 20 — Rising Stars in Houston Health Tech

Join General Assembly for an epic night with some of the Houston's most inspiring healthtech founders and leaders. In a candid discussion, they'll share their stories and insights.

Details: The event is from 6:30 to 9 pm on Thursday, February 20, at GA Houston (1301 Fannin St, Floor 21). Learn more.

February 24 — Made in Houston: Celebrating Black History Month

In honor of Black History Month, General Assembly has organized an evening with some of Houston's legendary innovators and creators. Each speaker will share their tips and tricks on how to create a unique product, service or brand that's pushing the boundaries while sharing their journey.

Details: The event is from 6:30 to 9 pm on Monday, February 24, at GA Houston (1301 Fannin St, Floor 21). Learn more.

February 25 — The Cannon Lunch & Learn: Show me the Money

As an early stage company, raising capital is or will be a significant part of your efforts and can present major challenges. Preparation and an understanding of what drives value is crucial to attracting investors. Join Cannon partner, Baker Tilly, as they provide an overview of the capital raise process and highlight key factors to consider when preparing to raise capital.

Details: The event is from 11:30 am to 1 pm on Tuesday, February 25, at The Cannon (1334 Brittmoore Road). Learn more.

Vivante Health, which uses technology and at-home testing to help users treat chronic digestive health issues, has raised $5.8 million. Getty Images

Digital health startup based in Houston closes $5.8 million round

Money moves

A Houston health technology startup that uses digital solutions and on-demand support to help its users with digestive health has closed a Series A round of funding.

Vivante Health raised $5.8 million in a series A1 round, according to a news release. The round was led by California-based Lifeforce Capital and Athens, Greece-based Big Pi Ventures. Additionally, NFP Ventures, FCA Venture Partners, and Longmont Capital contributed to the round.

"We knew we were onto something when the market responded so positively," says Dr. Kimon Angelides, Vivante Health founder and CEO, in the release, "but support from esteemed, experienced and successful firms like Lifeforce and Big Pi, and the continued strong support from our initial investor partners, give us a very encouraging boost of confidence as we carry out our vision and further develop the GIThrive platform."

With the fresh funds, Vivante will continue to develop its GI health platform, GIThrive. The digital tool has an at-home microbiome test kit for users, as well as a breath tester that monitors food sensitivities. GIThrive also connects users to on-demand support from nutritionists and experts on the GIThrive app.

The startup's Houston headquarters is based out of the Johnson & Johnson Innovation Center, JLabs@TMC, but has offices in Nashville, Chicago, and Athens. Angelides, who honors his Greek heritage by spending a fair about of time in Greece, says in the release how important the Big Pi investment is for him.

"This partnership with Big Pi, a tech-based investment firm who's driven by the desire to support Greek talent, makes perfect sense. What's more, we have partnered with a team who themselves have been very successful entrepreneurs," says Angelides in the release.

Angelides, who has founded three other health tech companies, impressed Big Pi with his entrepreneurial track record and nationwide team

"This is one of those rare investments where the financial upside goes hand in hand with the prospect of radically improving the lives of millions of people across the globe," says Marco Veremis, investment partner with Big Pi, in the release.

Lifeforce Capital has a portfolio of software startups, including Aspire, Cricket Health, Notable Labs, One Medical, and Second Genome, per the news release, and the VC firm is excited for their new addition.

"We were immediately struck by Kim's entrepreneurial passion and big vision," says Sander Duncan, general partner with Lifeforce Capital, in the release. "We are thrilled to work with the Vivante team to build the first platform tackling digestive disease for millions of suffering patients."

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CultureMap Emails are Awesome

Houston hailed as one of America's 10 best cities for startups

Startup Report

Houston's favorable economic climate is enticing new opportunities for entrepreneurship and growth, and now the city is being hailed as the 7th-best U.S. city for starting a business.

The recognition comes in CommercialCafe's recent "Best Cities for Startups" report, published December 10. The study analyzed large U.S. cities across two population categories – cities with more than 1 million residents and cities with populations between 500,000 and 1 million residents. The report analyzed relevant metrics such as office or coworking costs, Kickstarter funding success, startup density, and survival rates, among others.

Across the biggest U.S. cities with over a million residents, Phoenix, Arizona landed on top as the No. 1 best place to start a new business.

The report's findings revealed 10.6 percent of all businesses in Houston are startups that have been active for less than a year. These new businesses have a survival rate of 64.5 percent, meaning just under two-thirds of all startups in the city will still be running up to five years after they were first established.

Over the last five years, the number of new businesses established in Houston has grown nearly 15 percent. CommercialCafe said new businesses in cities with high startup growth rates tend to "attract top talent" which can eventually lead to securing "vital funding for expansion."

Independent professionals – also known as freelancers – are another crucial resource for new businesses that may need "specialized services" for a fixed amount of time, the report said. Houston's freelance workforce has grown about 9 percent from 2019-2023, and the analysis found there were 97,295 freelancers working in Houston in 2023, compared to 89,528 in 2019.

"Generally, cities in the South and Southwest have experienced strong growth during the surveyed period, in contrast to California cities like Los Angeles and San Diego, where the share of freelancers and gig workers has either stagnated or slightly declined," the report said.

Houston boasts the second-cheapest office space rent nationally, the report found. The average asking price for a 1,000-square-foot workspace (for five employees) in the city added up to $27,124 annually. For startups that want greater flexibility for their workers, the annual cost for a coworking space for the same number of employees in Houston came out to $13,200, which is the fourth-most affordable rate in the U.S.

Other Texas cities with attractive economic environments for startups

Texas, as a whole, is one of the strongest states for starting a new business. Other than Houston, San Antonio (No. 2), Dallas (No. 3), and Fort Worth (No. 4) were also recognized among the top 10 best places to start a business in the category of U.S. cities with more than a million residents.

Austin topped a separate ranking of best cities to start a business with 500,000 to 1 million residents.

"Specifically, the Texas capital was the frontrunner for indicators that looked at the overall share of startups within the local economy, as well as growth rates in five years (2019 to 2023)," the report said. "On top of that, Austin also topped the rankings for its percentage of college-educated residents and its consulting firms, which provide vital support for burgeoning enterprises."

The top 10 best cities to start a new business are:

  • No. 1 – Phoenix, Arizona
  • No. 2 – San Antonio, Texas
  • No. 3 – Dallas, Texas
  • No. 4 – Fort Worth, Texas
  • No. 5 – Jacksonville, Florida
  • No. 6 – San Diego, California
  • No. 7 – Houston, Texas
  • No. 8 – Philadelphia, Pennsylvania
  • No. 9 – Chicago, Illinois
  • No. 10 – Los Angeles, California
---

This article originally appeared on CultureMap.com.

Top Houston space news of 2025 soars with NASA deals, lunar missions

Year in Review

Editor's note: As 2025 comes to a close, we're looking back at the stories that defined Houston innovation this year. The space tech sector soared with companies landing huge NASA contracts and furthering their lunar missions. Here are the 10 biggest Houston space tech stories of the year:

Houston native picked for 2025 class of NASA astronaut candidates

Houston native Anna Menon, posing below the first A in “NASA,” is one of 10 new NASA astronaut candidates. Photo courtesy NASA.

NASA has selected 10 new astronaut candidates, including one whose hometown is Houston, for its 2025 training class. The candidates will undergo nearly two years of training before they can assume flight assignments.

Intuitive Machines lands $9.8M to complete orbital transfer vehicle

Intuitive Machines expects to begin manufacturing and flight integration on its orbital transfer vehicle as soon as 2026. Photo courtesy Intuitive Machines.

Houston-based Intuitive Machines, which rang the NASDAQ opening bell July 31, secured a $9.8 million Phase Two government contract for its orbital transfer vehicle. The contract will push the project through its Critical Design Review phase, which is the final engineering milestone before manufacturing can begin.

Houston tech company tapped by NASA for near space initiative

Intuitive Machines is among four companies awarded contracts for NASA’s Near Space Network. Photo via intuitivemachines.com

In January, Intuitive Machines nailed down a NASA deal to expand the agency’s communications network for spacecraft. Additionally, NASA completed the first round of “human in the loop” testing for Intuitive Machines’ Moon RACER lunar terrain vehicle at the agency’s Johnson Space Center. RACER (Reusable Autonomous Crewed Exploration Rover) is one of three commercially developed unpressurized lunar terrain vehicles being considered for NASA’s Artemis lunar initiative.

Texas Space Commission doles out $5.8 million to Houston companies

Axiom Space and FluxWorks are the latest Houston-area companies to receive funding from the Texas Space Commission. Photo via Getty Images.

Two Houston-area companies landed more than $5.8 million in funding from the Texas Space Commission. The commission granted up to $5.5 million to Houston-based Axiom Space and up to $347,196 to Conroe-based FluxWorks in June 2025. The two-year-old commission previously awarded $95.3 million to 14 projects. A little over $34 million remains in the commission-managed Space Exploration and Aeronautics Research Fund.

Houston company awarded $2.5B NASA contract to support astronaut health and space missions

NASA has awarded KBR a five-year, $2.5 billion Human Health and Performance Contract. Photo courtesy NASA.

Houston-based technology and energy solution company KBR was awarded a $2.5 billion NASA contract to support astronaut health and reduce risks during spaceflight missions. Under the terms of the Human Health and Performance Contract 2, KBR will provide support services for several programs, including the Human Research Program, International Space Station Program, Commercial Crew Program, Artemis campaign and others. This will include ensuring crew health, safety, and performance; occupational health services and risk mitigation research for future flights.

Houston engineering firm lands $400M NASA contract

Bastion Technologies has been tapped to provide safety and mission services for NASA's Marshall Space Flight Center in Alabama. Photo via nasa.gov.

NASA granted Houston-based Bastion Technologies Inc. the Safety and Mission Assurance II (SMAS II) award with a maximum potential value of $400 million. The award stipulates that the engineering and technical services company provide safety and mission services for the agency’s Marshall Space Flight Center in Huntsville, Alabama.

Houston startups win NASA funding for space tech projects

Houston startups were recently named among the nearly 300 recipients that received a portion of $44.85 million from NASA to develop space technology. Photo via NASA/Ben Smegelsky

Three Houston startups were granted awards from NASA in July 2025 to develop new technologies for the space agency. The companies were among nearly 300 recipients that received a total agency investment of $44.85 million through the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase I grant programs.

Texas Republicans are pushing to move NASA headquarters to Houston

Here's why Texas Republicans think NASA's headquarters should move to Texas in 2028. File photo.

Two federal lawmakers from Texas spearheaded a campaign to relocate NASA’s headquarters from Washington, D.C., to the Johnson Space Center in Houston’s Clear Lake area. Houston faces competition on this front, though, as lawmakers from two other states are also vying for this NASA prize. With NASA’s headquarters lease in D.C. set to end in 2028, U.S. Sen. Ted Cruz, a Texas Republican, and U.S. Rep. Brian Babin, a Republican whose congressional district includes the Johnson Space Center, wrote a letter to President Trump touting the Houston area as a prime location for NASA’s headquarters.

Intuitive Machines to acquire NASA-certified deep space navigation company

Intuitive Machines will acquire Kinetx, which marks its entry into the precision navigation and flight dynamics segment of deep space operations. Photo via Getty Images.

In August 2025, Intuitive Machines agreed to buy Tempe, Arizona-based aerospace company KinetX for an undisclosed amount. The deal is expected to close by the end of this year. KinetX specializes in deep space navigation, systems engineering, ground software and constellation mission design. It’s the only company certified by NASA for deep space navigation. KinetX’s navigation software has supported both of Intuitive Machines’ lunar missions.

Axiom Space launches semiconductor and astronaut training initiatives

Axiom Space chief astronaut Michael López-Alegría (left) trains with Axiom’s new “Project Astronaut,” Emiliano Ventura. Photo courtesy of Axiom Space.

In fall 2025, Axiom Space, a Houston-based commercial spaceflight and space infrastructure company, launched initiatives in two very different spheres — semiconductors and astronaut training.

Paraplegic engineer becomes first wheelchair user to blast into space

Space News

A paraplegic engineer from Germany blasted off on a dream-come-true rocket ride with five other passengers Saturday, December 20, leaving her wheelchair behind to float in space while beholding Earth from on high.

Severely injured in a mountain bike accident seven years ago, Michaela Benthaus became the first wheelchair user in space, launching from West Texas with Jeff Bezos’ company Blue Origin. She was accompanied by a retired SpaceX executive also born in Germany, Hans Koenigsmann, who helped organize and, along with Blue Origin, sponsored her trip. Their ticket prices were not divulged.

An ecstatic Benthaus said she laughed all the way up — the capsule soared more than 65 miles (105 kilometers) — and tried to turn upside down once in space.

“It was the coolest experience,” she said shortly after landing.

The 10-minute space-skimming flight required only minor adjustments to accommodate Benthaus, according to the company. That’s because the autonomous New Shepard capsule was designed with accessibility in mind, “making it more accessible to a wider range of people than traditional spaceflight,” said Blue Origin’s Jake Mills, an engineer who trained the crew and assisted them on launch day.

Among Blue Origin’s previous space tourists: those with limited mobility and impaired sight or hearing, and a pair of 90-year-olds.

For Benthaus, Blue Origin added a patient transfer board so she could scoot between the capsule’s hatch and her seat. The recovery team also unrolled a carpet on the desert floor following touchdown, providing immediate access to her wheelchair, which she left behind at liftoff. She practiced in advance, with Koenigsmann taking part with the design and testing. An elevator was already in place at the launch pad to ascend the seven stories to the capsule perched atop the rocket.

Benthaus, 33, part of the European Space Agency’s graduate trainee program in the Netherlands, experienced snippets of weightlessness during a parabolic airplane flight out of Houston in 2022. Less than two years later, she took part in a two-week simulated space mission in Poland.

“I never really thought that going on a spaceflight would be a real option for me because even as like a super healthy person, it’s like so competitive, right?” she told The Associated Press ahead of the flight.

Her accident dashed whatever hope she had. “There is like no history of people with disabilities flying to space," she said.

When Koenigsmann approached her last year about the possibility of flying on Blue Origin and experiencing more than three minutes of weightlessness on a space hop, Benthaus thought there might be a misunderstanding. But there wasn't, and she immediately signed on.

It’s a private mission for Benthaus with no involvement by ESA, which this year cleared reserve astronaut John McFall, an amputee, for a future flight to the International Space Station. The former British Paralympian lost his right leg in a motorcycle accident when he was a teenager.

An injured spinal cord means Benthaus can’t walk at all, unlike McFall who uses a prosthetic leg and could evacuate a space capsule in an emergency at touchdown by himself. Koenigsmann was designated before flight as her emergency helper; he and Mills lifted her out of the capsule and down the short flight of steps at flight’s end.

“You should never give up on your dreams, right?” Benthaus urged following touchdown.

Benthaus was adamant about doing as much as she could by herself. Her goal is to make not only space accessible to the disabled, but to improve accessibility on Earth too.

While getting lots of positive feedback within “my space bubble,” she said outsiders aren't always as inclusive.

“I really hope it’s opening up for people like me, like I hope I’m only the start," she said.

Besides Koenigsmann, Benthaus shared the ride with business executives and investors, and a computer scientist. They raised Blue Origin’s list of space travelers to 86.

Bezos, the billionaire founder of Amazon, created Blue Origin in 2000 and launched on its first passenger spaceflight in 2021. The company has since delivered spacecraft to orbit from Cape Canaveral, Florida, using the bigger and more powerful New Glenn rocket, and is working to send landers to the moon.