This digital shopping assistant relocated to Texas last year to focus on the business-friendly market. Courtesy of ModeSens

Former Microsoft engineer Brian Li wanted to help his wife, Jing Leng, a personal shopper, make smart purchases for her clients seeking luxury clothing. The couple found it impractical and time consuming to sift through multiple websites in search of clothing that was the best fit.

Li, now CEO of ModeSens, was inspired in 2015 to develop a personal shopping tool. The name comes from rearranging the French phrase "sens de la mode," which means "fashion sense."

"It started out as something that Brian worked on in his free time. But after they started using it, they realized that other people would find it useful," says Krystle Craycraft, CMO of ModeSens. "Another resource like this does not exist. We are the only company that aggregates information at the product level, presenting information to consumers in a way that is easy to navigate, and all in one place."

Since launching in 2015 in Seattle, the company relocated to Texas last year. Now, headquartered in Dallas, the company is building a large pool of users in major cities throughout Texas. ModeSens sees a growing connection with Houston in terms of customers and fashion retailers.

Li moved the business "because Texas is a good place to do business," Craycraft says. "Many businesses are following the trend of moving to Texas because of the great climate to do business in. We love Texas."

ModeSens, using its database of information, gives luxury fashion shoppers important information about products as they search, making for a more efficient, satisfying purchase. For a given item, ModeSens provides members a list of retailers who have the item in stock, the price comparison across retailers, available colors, designer information, product reviews, special promotions, and more.

You can download the free app, create a free account, and start saving on luxury goods by searching the site or scanning barcodes in the store. As ModeSens specializes in luxury goods, they partner with almost 200 brands such as Neiman Marcus, SAKS, Gucci, Dolce & Gobana, Lane Crawford and other premier designers.

"We connect with clients through several different affiliate networks as well as direct partnerships," says Craycraft. ModeSens partners exclusively with high-end retailers, filling a specific niche for the first time.

Leng, serving as the Fashion Director at ModeSens, works with these retail partners, curating content and promoting their products in a way that helps customers buy confidently.

"The customer is the focus of ModeSens; getting them what they need to make an informed decision is our top priority," says Craycraft. "Other fashion shopping platforms show products from Forever 21 all the way up to luxury brands, but for our customers looking for luxury products, a lot of those stores are just not relevant to them. Sorting through them becomes tedious."

ModeSens puts the answers to at customers' questions at their fingertips, once signed up with a free membership.

With the brand-new release of the barcode scanning feature, customers can have access to the same comparative information while physically in a store, as well as online.

"This is a total game-changer in the industry; there is no one else doing this," says Craycraft.

Using the app, shoppers simply scan the barcode of any of the many retailers who are partnered with ModeSens, revealing detailed information that can guide their purchase.

ModeSens is building an online community of luxury shoppers that can collaborate to find exactly what they are looking for in an authentic way. Through the website, members can upload pictures of the products that they have acquired, write reviews, provide helpful information to others, and ask questions.

"We want this to be a place where anyone can share their thoughts, and photos without feeling too intimidated to contribute," Craycraft says.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.