Dr. Jenny Chang's cancer research has generated more than $35 million in funding for Houston Methodist. Photo courtesy Houston Methodist

Houston Methodist Academic Institute has named cancer clinician and scientist Dr. Jenny Chang as its new executive vice president, president, CEO, and chief academic officer.

Chang was selected following a national search and will succeed Dr. H. Dirk Sostman, who will retire in February after 20 years of leadership. Chang is the director of the Houston Methodist Dr. Mary and Ron Neal Cancer Center and the Emily Herrmann Presidential Distinguished Chair in Cancer Research. She has been with Houston Methodist for 15 years.

Over the last five years, Chang has served as the institute’s chief clinical science officer and is credited with strengthening cancer clinical trials. Her work has focused on therapy-resistant cancer stem cells and their treatment, particularly relating to breast cancer.

Her work has generated more than $35 million in funding for Houston Methodist from organizations like the National Institutes of Health and the National Cancer Institute, according to the health care system. In 2021, Dr. Mary Neal and her husband Ron Neal, whom the cancer center is now named after, donated $25 million to support her and her team’s research on advanced cancer therapy.

In her new role, Chang will work to expand clinical and translational research and education across Houston Methodist in digital health, robotics and bioengineered therapeutics.

“Dr. Chang’s dedication to Houston Methodist is unparalleled,” Dr. Marc L. Boom, Houston Methodist president and CEO, said in a news release. “She is committed to our mission and to helping our patients, and her clinical expertise, research innovation and health care leadership make her the ideal choice for leading our academic mission into an exciting new chapter.”

Chang is a member of the American Association of Cancer Research (AACR) Stand Up to Cancer Scientific Advisory Council. She earned her medical degree from Cambridge University in England and completed fellowship training in medical oncology at the Royal Marsden Hospital/Institute for Cancer Research. She earned her research doctorate from the University of London.

She is also a professor at Weill Cornell Medical School, which is affiliated with the Houston Methodist Academic Institute.

Houston Methodist received millions in donations to support cancer patients. Courtesy of Methodist Hospital/Facebook

Houston hospital receives $37M in donations to continue its life-saving cancer care

guardian angels

A $25 million gift will support expansion of research conducted at the Houston Methodist Cancer Center and may help the center earn top-tier federal designation.

In honor of the $25 million donation from Dr. Mary Neal and husband Ron Neal, the cancer center is being renamed the Houston Methodist Dr. Mary and Ron Neal Cancer Center. The hospital system will raise an additional $12 million in matching funds, bringing the total to $37 million.

Dr. Marc Boom, president and CEO of Houston Methodist, says the Bellaire couple's gift "plays an important role in advancing our leading medicine mission and bringing potentially life-saving cancer treatments to more patients throughout Houston and the nation."

Mary Neal, previously in private practice as an obstetrician-gynecologist, is now a part-time volunteer physician at Houston Methodist's San Jose Clinic. Ron Neal is co-founder and co-owner of offshore development company Houston Energy. He also is CEO of Houston-based HEQ Deepwater, a more than $400 million venture formed earlier this year by Houston Energy and Houston-based private equity firm Quantum Energy Partners to buy deepwater assets in the Gulf of Mexico.

With the donation from Dr. Mary Neal and husband Ron Neal, the cancer center is being renamed the Houston Methodist Dr. Mary and Ron Neal Cancer Center. Photo courtesy of Houston Methodist

The Neals' donation will boost ongoing research led by Dr. Jenny Chang, director of the cancer center and Emily Herrmann Presidential Distinguished Chair in Cancer Research. Chang's research has advanced cancer therapy with breakthroughs such as targeted drugs for treatment of breast cancer.

Mary Neal says she and her husband believe their contribution "will further advance pivotal and innovative research beyond chemotherapy and radiation."

The gift also will fund and retain three endowed chairs and complementary funding for early stage research and therapies, support recruitment and fellowship training, and expand clinical trials at all of the community hospitals within Houston Methodist. Part of the gift is dedicated to cancer innovation efforts within the Center for Drug Repositioning and Development.

"Our vision for the Dr. Mary and Ron Neal Cancer Center is to grow our network of cancer physicians offering comprehensive care with the latest technologies and clinical trials so that patients across the region have the best access to cancer care," Chang says. "While the gift from the Neal family will have direct impact for patients at the community level in areas that are often deserts for cancer care, my hope is that it will also propel our ongoing research and work to the national level toward NCI designation."

Cancer centers designated by the National Cancer Institute (NCI) meet rigorous standards for research and clinical care. The Neals' gift is aimed at elevating research done at the cancer center and helping retain talent to accelerate Houston Methodist's pursuit of NCI designation.

Texas is home to four NCI-designated cancer centers:

  • Dan L Duncan Comprehensive Cancer Center at Houston's Baylor College of Medicine.
  • University of Texas MD Anderson Cancer Center, also in Houston.
  • Harold C. Simmons Comprehensive Cancer Center at the University of Texas Southwestern Medical Center in Dallas.
  • Mays Cancer Center at the University of Texas Health Science Center in San Antonio.

NCI designation represents "the highest federal rating a cancer center can achieve," according to the University of Chicago's NCI-designated cancer center. "It's the gold standard for cancer programs, and is bestowed upon the nation's top cancer centers in recognition of their innovative research and leading-edge treatments."

This designation can lead to benefits such as more research grants, quicker access to clinical trials for cancer treatments, and stepped-up recruitment of high-profile cancer researchers.

"At any given time, hundreds of research studies are under way at the cancer centers, ranging from basic laboratory research to clinical assessments of new treatments," the NCI says. "Many of these studies are collaborative and may involve several cancer centers, as well as other partners in industry and the community."

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Texas space co. takes giant step toward lunar excavator deployment

Out of this world

Lunar exploration and development are currently hampered by the fact that the moon is largely devoid of necessary infrastructure, like spaceports. Such amenities need to be constructed remotely by autonomous vehicles, and making effective devices that can survive the harsh lunar surface long enough to complete construction projects is daunting.

Enter San Antonio-based Astroport Space Technologies. Founded in San Antonio in 2020, the company has become a major part of building plans beyond Earth, via its prototype excavator, and in early February, it completed an important field test of its new lunar excavator.

The new excavator is designed to function with California-based Astrolab's Flexible Logistics and Exploration (FLEX) rover, a highly modular vehicle that will perform a variety of functions on the surface of the moon.

In a recent demo, the Astroport prototype excavator successfully integrated with FLEX and proceeded to dig in a simulated lunar surface. The excavator collected an average of 207 lbs (94kg) of regolith (lunar surface dust) in just 3.5 minutes. It will need that speed to move the estimated 3,723 tons (3,378 tonnes) of regolith needed for a lunar spaceport.

After the successful test, both Astroport and Astrolab expressed confidence that the excavator was ready for deployment. "Leading with this successful excavator demo proves that our technology is no longer theoretical—it is operational," said Sam Ximenes, CEO of Astroport.

"This is the first of many implements in development that will turn Astrolab's FLEX rover into the 'Swiss Army Knife' of lunar construction. To meet the infrastructure needs of the emerging lunar economy, we must build the 'Port' before the 'Ship' arrives. By leveraging the FLEX platform, we are providing the Space Force, NASA, and commercial partners with a 'Shovel-Ready' construction capability to secure the lunar high ground."

"We are excited to provide the mobility backbone for Astroport's groundbreaking construction technology," said Jaret Matthews, CEO of Astrolab, in a release. "Astrolab is dedicated to establishing a viable lunar ecosystem. By combining our FLEX rover's versatility with Astroport's civil engineering expertise, we are delivering the essential capabilities required for a sustainable lunar economy."

---

This article originally appeared on CultureMap.com.

Houston biotech co. raises $11M to advance ALS drug development

drug money

Houston-based clinical-stage biotechnology company Coya Therapeutics (NASDAQ: COYA) has raised $11.1 million in a private investment round.

India-based pharmaceuticals company Dr. Reddy’s Laboratories Inc. led the round with a $10 million investment, according to a news release. New York-based investment firm Greenlight Capital, Coya’s largest institutional shareholder, contributed $1.1 million.

The funding was raised through a definitive securities purchase agreement for the purchase and sale of more than 2.5 million shares of Coya's common stock in a private placement at $4.40 per share.

Coya reports that it plans to use the proceeds to scale up manufacturing of low-dose interleukin-2 (IL-2), which is a component of its COYA 302 and will support the commercial readiness of the drug. COYA 302 enhances anti-inflammatory T cell function and suppresses harmful immune activity for treatment of Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s disease and Alzheimer’s disease.

The company received FDA acceptance for its investigational new drug application for COYA 302 for treating ALS and FTD this summer. Its ALSTARS Phase 2 clinical trial for ALS treatment launched this fall in the U.S. and Canada and has begun enrolling and dosing patients. Coya CEO Arun Swaminathan said in a letter to investors that the company also plans to advance its clinical programs for the drug for FTD therapy in 2026.

Coya was founded in 2021. The company merged with Nicoya Health Inc. in 2020 and raised $10 million in its series A the same year. It closed its IPO in January 2023 for more than $15 million. Its therapeutics uses innovative work from Houston Methodist's Dr. Stanley H. Appel.

New accelerator for AI startups to launch at Houston's Ion this spring

The Collectiv Foundation and Rice University have established a sports, health and wellness startup accelerator at the Ion District’s Collectiv, a sports-focused venture capital platform.

The AI Native Dual-Use Sports, Health & Wellness Accelerator, scheduled to formally launch in March, will back early-stage startups developing AI for the sports, health and wellness markets. Accelerator participants will gain access to a host of opportunities with:

  • Mentors
  • Advisers
  • Pro sports teams and leagues
  • University athletics programs
  • Health care systems
  • Corporate partners
  • VC firms
  • Pilot projects
  • University-based entrepreneurship and business initiatives

Accelerator participants will focus on sports tech verticals inlcuding performance and health, fan experience and media platforms, data and analytics, and infrastructure.

“Houston is quickly becoming one of the most important innovation hubs at the intersection of sports, health, and AI,” Ashley DeWalt, co-founder and managing partner of The Collectiv and founder of The Collectiv Foundation, said in a news release.

“By launching this platform with Rice University in the Ion District,” he added, “we are building a category-defining acceleration engine that gives founders access to world-class research, global sports properties, hospital systems, and venture capital. This is about turning sports-validated technology into globally scalable companies at a moment when the world’s attention is converging on Houston ahead of the 2026 World Cup.”

The Collectiv accelerator will draw on expertise from organizations such as the Rice-Houston Methodist Center for Human Performance, Rice Brain Institute, Rice Gateway Project and the Texas Medical Center.

“The combination of Rice University’s research leadership, Houston’s unmatched health ecosystem, and The Collectiv’s operator-driven investment platform creates a powerful acceleration engine,” Blair Garrou, co-founder and managing partner of the Mercury Fund VC firm and a senior adviser for The Collectiv, added in the release.

Additional details on programming, partners and application timelines are expected to be announced in the coming weeks.