Rice University's Owl Spark and the University of Houston’s RED Labs will culminate at The Bayou Startup Showcase in July. Photo courtesy Rice University.

OwlSpark, a startup and small business accelerator for Rice University-affiliated ventures, has named the latest 11 companies to its program that focus on challenges across technology, health care, consumer products and other sectors. The program is hosted in tandem with the University of Houston’s RED Labs and will take place at the Ion.

The early-stage accelerator runs for 12 weeks and culminates at The Bayou Startup Showcase on July 31.

According to a news release from Rice, “the accelerator cultivates a vibrant environment where founders are empowered to build, test, and scale their ideas in a setting built for entrepreneurship.”

The program is divided into two tracks: one for high-growth tech startups and another for small businesses.

The latest OwlSpark class includes:

  • Web and mobile platform EasilyBEE, which boosts family and community engagement in K-12 schools
  • Diagnos, a wearable-integrated wellness platform that monitors health and prevents injuries in college athletes
  • Johnnie, an AI-powered records management software for rural and midsize first responder agencies
  • JustKindHumility, which offers faith-based travel journals
  • Klix, which automates early-stage clinical trial management from document screening to AI-driven patient outreach and eligibility checks
  • Lizzy’s Gourmet Gains, which offers high-protein, flavor-forward dips and dressings
  • NextStep, an AI-powered multilingual assistant helping underserved communities navigate resources for health care
  • A catheter-integrated sensor device PeriShield, which detects early infection in peritoneal dialysis patients
  • Right Design, which connects creatives with vetted employers, mentors and projects via job matching and commissions
  • UCoreAlly, which provides business support for biotech startups in marketing, business development, customer support, human resources and accounting
  • Ultrasound-based ablation system VentriTech that treats ventricular arrhythmias

The Owl Spark accelerator has supported 229 founders and launched 104 ventures with participants raising more than $116 million in funding since 2013, according to Rice.

UH also shared the 9 teams that will participate in RED Labs' latest cohort.

The latest RED Labs class includes:

  • BLEED, an art agency that helps artists commercialize their work by connecting art collectors to original artwork and artists
  • Brain Haven, which is developing nasal inhalers designed to stimulate the emotional and memory processing centers to preserve neuroplasticity and delay cognitive decline
  • Candi Wands Automated Cotton Candy, which has developed a continuously operating cotton candy machine to help entertainment venues boost passive revenue
  • ChériCollectible, a series of in-person events where Gen Z and collectors can buy, sell, and trade modern collectibles
  • JobRadar, a job board that uses AI to analyze and categorize positions in real-time and then apply candidates instantly
  • Stage Select LLC, a supplementary talent booking service that partners with multi-stage venues to help fill gaps in programming and increase profitability by finding and booking local talent for their "second stage."
  • P-LEGS, a pediatric lower-limb exoskeleton that reduces physical strain on therapists while delivering customizable gait training.
  • Roll ‘N’ Reel Photo Booth, an interactive event-based equipment rental business
  • Stayzy, which automates guest communication and handles maintenance issues with an AI-powered software for short-term rental companies that manage 20-plus rentals
Don't miss these March events — from CERAWeek to the Ion's Mardi Gras block party. Image via houston.org

10 can't-miss Houston business and innovation events for March

where to be

Editor's note: March is here, and that means the return of some of Houston’s signature innovation events, as well as insightful talks and a Mardi Gras block party. Here are the Houston business and innovation events you can't miss in March and how to register. Please note: this article might be updated to add more events.

March 5 – SheSpace Women’s Day Open House

Connect with like-minded women during a free day of coworking at SheSpace. And while you're there, take a break and enjoy a floral arranging class, complimentary breakfast, pop-up shops, happy hour and raffle prizes. Space is limited.

The event is Wednesday, March 5, from 9 a.m.–7 p.m. Click here to register.

March 5 — Science and the American Presidency

Hear from former presidential science advisors—Kelvin Droegemeier who served under President Trump, Neal Lane who served under President Clinton and Alondra Nelson who served under President Biden—as they discuss their experiences leading the White House Office of Science and Technology Policy and how science is used to address issues from climate change and public health to national security and economic competitiveness. An exhibit inside Baker Hall will complement the event. The Baker Institute Science and Technology Policy Program and Rice Innovation will host the talk.

This event is Wednesday, March 5, from 5:30–8 p.m. at James A. Baker Hall. Click here to register.

March 6 — Ion Block Party - Mardi Gras Edition 

Let the good times roll this week while networking with potential collaborators, mentors and investors at the Ion. Food and drink will be available while supplies last and the Ion will provide drink tickets for one free drink at Second Draught upon check-in.

This event is Thursday, March 6, from 4–7 p.m. at the Ion. Click here to register.

March 10-14 — CERAWeek 2025

The foremost annual gathering in the energy sector returns to Houston March 10-14, 2025. Themed "Moving Ahead: Energy strategies for a complex world," CERAWeek 2025 will focus on the challenges ahead for energy security, supply, and climate ambitions. More than 10,000 participants from over 2,050 companies across 80 countries will convene in Houston for this ambitious event. CERAWeek comprises three platforms: the Executive Conference, the Innovation Agora, and Partner Programs. We'll dive into comprehensive CERAWeek recommendations in future articles.

This event begins Monday, March 10. Click here to register.

March 11 — Energy Venture Day at the Ion

Preview pitches from 40-plus energy ventures competing at CERAWeek's Energy Venture Day and Pitch Competition, co-hosted by the Rice Alliance, Ion, HETI, and TEX-E. This free, fast-paced pitch event offers an alternative to the CERAWeek event, which requires an Agora pass.

This event is Tuesday, March 11, from 9 a.m.–2:30 p.m. Click here to register.

March 13 — Code4Y'allMeetup

Connect with fellow coders at Code4Y’all's meetup at the Ion. Andrew Baines, Founder of No Experience Jobs, will present "How I Built a Job Board to Help Entry-Level Tech Talent (And What I Learned)." Hear from Baines and learn lessons from job seekers.

This event is Thursday, March 13, from 6–7 p.m. Click here to register.

March 13-14 — Veterans Business Battle

Hear pitches from veterans and entrepreneurs as they compete for $5 million in investments at Rice Businesses' 11th annual Veterans Business Battle. This year, the two-day event will also feature a Small Business Expo which invites Houston-based, veteran-owned businesses to participate in education, networking, and the opportunity to showcase their business.

This event begins Thursday, March 13, at 11:30 a.m. at McNair Hall on Rice's campus. Click here to register.

March 17 — Women in Innovation 

Celebrate Women's History Month with an engaging panel discussion hosted by the University of Houston's Division of Energy and Innovation. UH's Tanu Chatterji, Stacey Gorniak and Chrysa Latrick will discuss the achievements of trailblazing women across various industries, as well as share challenges and experiences. Lunch will be provided.

This event is Monday, March 17, from noon–1 p.m. at UH's Faculty Cafe. Find more information here.

March 24-28 — H-Town Roundup 2025

Celebrate innovation, entrepreneurship and collaboration this month during Houston Exponential's H-Town Roundup. During the fifth-annual free event series, previously known as Houston Tech Rodeo, attendees can expect insightful talks, workshops and networking events at venues across the city like the Ion, Greentown Labs, University of Houston and more.

This event begins Monday, March 24. See the full schedule of events here.

​March 27 — NASA Tech Talks

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges NASA’s Johnson Space Center and the larger aerospace community are facing and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.

This event is Thursday, March 27, from 6-7 p.m. at the Ion. Register here.

Coworking company Industrious replaces WeWork-owned Common Desk at The Ion. Photo via thecommondesk.com

The Ion names new coworking partner for Houston innovation hub

Where to Work

Rice University subsidiary Rice Real Estate Co. has tapped coworking company Industrious as the new operator of the Ion’s 86,000-square-foot coworking space in Midtown. Industrious replaces WeWork-owned Common Desk in that role.

The Ion, owned by Rice Real Estate and located at 4201 Main St., is a 266,000-square-foot office building and innovation hub in the 16-acre Ion District.

Features of the coworking space include private suites and offices, dedicated desks, phone booths and conference rooms. In 2022, Common Desk said it was expanding the space by 28,000 square feet, bringing it to the current size.

“(Industrious’) unparalleled expertise in delivering quality, hospitality-driven workspaces complements our vision of creating a world-class ecosystem where entrepreneurs, corporations, and academia converge to drive innovation forward,” Ken Jett, president of Rice Real Estate, said in a statement.

Natalie Levine, senior manager of real estate at Industrious, says her company will work with Rice Real Estate “to continue to position the Ion as an invaluable contributor to the growth of Houston’s innovation community.”

Dallas-based commercial real estate services company CBRE said Jan. 14 that it had agreed to acquire Industrious in a deal valued at $400 million.

The Ion is Industrious’ second location in Houston. The company’s other local coworking space is at 1301 McKinney St.

Office tenants at the Ion include Occidental Petroleum, Fathom Fund, Activate, Carbon Clean, Microsoft and Chevron Technology Ventures.

UH's RED Labs and Rice's OwlSpark will be hosted at the Ion over 11 weeks of programming, networking, and training as each of the 18 participating companies are introduced to Houston's innovation ecosystem. Photo courtesy of the Ion

Rice, UH name student startup cohorts to annual summer accelerator

ready to grow

For the 11th year, Rice University and the University of Houston have teamed up to present their summer student accelerator programs.

UH's RED Labs and Rice's OwlSpark will be hosted at the Ion over 11 weeks of programming, networking, and training as each of the 18 participating companies are introduced to Houston's innovation ecosystem.

“The collaboration the University of Houston has with Rice University gives founders in RED Labs and OwlSpark a unique opportunity to grow along their peers in the larger Houston community and really exemplifies the spirit of collaboration that the Houston business ecosystem is known for,” Managing Director of RED Labs Liana Gonzalez-Schulenberg says in a news release. “It never fails to surprise me at the end of the summer the relationships built, the support systems created and collaborations produced across our universities. By working together, we empower the next generation of entrepreneurs to work together as they turn their visions into reality and drive positive change in the community.”

The programs conclude with the Bayou Startup Showcase on August 1, an event that's open to the public. Those interested can sign up online for more information.

“We’re celebrating more than just an 11-year partnership; we’re recognizing a dynamic alliance that has been instrumental in fostering entrepreneurship and propelling Houston to the forefront of innovation,” Managing Director of OwlSpark Jessica Fleenor adds. “This partnership exemplifies our dedication to cultivating a thriving environment where entrepreneurs can connect, grow and succeed surrounded by unparalleled resources and support. We are incredibly excited to see these new ventures grow as they join our growing network and are thrilled to host our cohorts at the Ion, positioning us at the core of our city’s vibrant innovation landscape.”

Here are the companies selected for each of the two programs, as outlined in the news release:

University of Houston RED Labs Class 12

  • Root Planters develops smart indoor plant care devices designed to prevent plant death by providing automatic watering, tailored for busy individuals and gardeners looking to maintain plant health with minimal effort.
  • Burb Groceries is an online grocery retailer for people with chronic health conditions.
  • That Dude’s Bakehouse offers premium, half-pound cookies, combining choice ingredients and craftsmanship with the mission of being the best part of somebody’s day
  • Mulligan Bandit aims to redefine golf fashion, offering affordable yet high-quality clothing that seamlessly transitions from the fairway to the streets, reflecting personal style while ensuring durability and comfort.
  • Surreal Vision offers immersive mixed reality solutions that provide dynamic visualization experiences to enhance design collaboration and client presentations.
  • Agave Catering is a catering company focused on providing high-quality, gourmet boxed lunches for professionals on the go.
  • Digitally Marie is a purposeful creative agency dedicated to reducing the opportunity gap for female entrepreneurs. Through our heart-driven approach, we elevate content production embodying their brand perception with unapologetic authenticity.
  • Unison is a personal contact relationship management tool that alleviates the risk of data loss and helps to build more meaningful professional and personal relationships.
  • Brain-eNet is a platform that provides hardware and software tools to enable the development of brain-controlled Internet of Things applications.
  • Pasha Blend Collection specializes in creating modern skincare products that embodies purity, authenticity and inclusivity.
  • Arresting Motion is a brand strategy design consultancy and marketing agency that transforms Houston’s top real estate firms into the brands they deserve.
  • CalliDanna is a consulting company that coaches girls 12 to 18 to help improve their lives professionally and personally.

Rice University OwlSpark Class 12

  • EcoFleet Solutions offers rechargeable electric power units for semitrucks, powering air conditioning and cabin functions during stops without engine idling, cutting fuel costs, maintenance and emissions.
  • Houston Community Print Shop offers printmaking classes and equipment access, focusing on community building and supporting underserved areas.
  • KOQ Agency curates and organizes global tours and live entertainment opportunities for queer and ally artists in drag, music and entertainment.
  • Euvivo Diagnostics is developing a direct-to-consumer test that analyzes cell aging by examining mitochondrial performance and new aging markers, tailored for individuals with mitochondrial disorders.
  • Hair Hub provides a compilation of styling tutorials, educational content, planning tools and a comprehensive database of products tailored for Black hair to provide resources for users to perform cost-efficient DIY haircare.
  • xMAD.ai is a compression-as-a-service platform that democratizes access to LLMs (Large Language Models) by making them faster, more private, cost-effective and accessible to businesses of all sizes.
Introducing the 10 startups participating in the Spring 2024 cohort of the DivInc Sports Tech Accelerator, a hybrid program based in the Ion. Photo via DivInc.com

10 sports tech startups named to Houston-based hybrid accelerator

game on

DivInc has named its latest sports tech-focused cohort of its hybrid accelerator that is housed out of the Ion.

The Sports Tech Accelerator has selected the 10 companies — with technology across human performance, fan experience, and more — for its 13th cohort to participate in the 12-week hybrid program this month and through July.

The program receives support from underdog venture team, Women In Sports Tech, The Collectiv, and HTX Sports Tech, with partners Bank of America, J.P. Morgan Chase & Co., Gunderson Dettmer, Brown Advisory, Ion, and Mercury.

The spring 2024 cohort includes:

  • Detroit-based Athlytic, which uses real-time data to develop a recommended minimum price per social platform for creator-athletes.
  • Ballin AI, from Tulsa, Oklahoma, is a unique scouting automation software, transforming the labor-intensive scouting process into a streamlined, data-driven operation that boasts improved efficiency over manual work.
  • Cache AI, founded in Bronx, New York, is a platform that uses AI to generate a score for athletes that brands can use to value them without bias.
  • Prosper, Texas-based DRAFTED is a platform to support the of Latina community in sports through digital storytelling, weekly newsletters, in-person and virtual programming, and collaborative brand partnerships.
  • From Chicago, Drip Tech Co. created an artificial intelligence concierge software that provides real-time hydration monitoring, digestible data, and actionable insights to both athletes and coaches.
  • Canadian company, Drive Hockey, founded in Coquitlam, British Columbia, developed an advanced skill-tracking system for aspiring young hockey athletes using sensors and AI technology to make NHL-level analytics simple & affordable for 120,000 amateur hockey teams.
  • Cincinnati, Ohio-based LunchTable is working on a fan activation and engagement platform that can mobilize fans into digital brand ambassadors.
  • Parscape, co-located in Chicago and Los Angeles, is a rewards and cash-back powered marketplace designed for the golf industry. Houston-based TRAINR is a platform for sports and performance coaches that offers booking, payments, taxes, CRM, content creation, financial services, nationwide access to training locations, and more.
  • From Rochester, New York, WEVOLV is working to improve decision making and a more equitable industry for athletes by using human and artificial intelligence and democratizing access.
Introducing: Houston Energy and Climate Startup Week, a collaborative initiative that will showcase Houston's ecosystem of energy tech innovators. Photo via Getty Images

Houston organizations team up to bring inaugural climate startup week

mark your calendars

Three organizations are teaming up to put on a week of programming and events focused on energy and climate startups.

Greentown Labs, Halliburton Labs, and the Rice Alliance for Technology and Entrepreneurship have announced Houston Energy and Climate Startup Week 2024 taking place September 9 to 13.

“These organizations will execute events that will serve as a launching pad for an Energy and Climate Startup Week in Houston, showcasing the city as a national hub for the energy future,” Brad Burke, executive director of the Rice Alliance, says in the release. “We welcome the community to bring other energy and climate events to the week, which we’ll cross-promote as the dates approach.”

The week will assemble investors, industry leaders, and startups from across the energy industry and from around the world to showcase Houston's growing sustainable, low-carbon energy future.

The initiative is in collaboration with the Houston Energy Transition Initiative, or HETI, an initiative of the Greater Houston Partnership, as well as Activate, Digital Wildcatters, Renewable Energy Alliance Houston, and TEX-E.

“As the energy capital and one of the most diverse cities in the world, Houston stands as a center point for these solutions. The region is welcoming, diverse and has the know-how to play a critical role in building an energy abundant, low-carbon future," Jane Stricker, executive director of HETI and senior vice president at GHP, says in the release. "We welcome all who want to be part of the solution to join for this exciting, inaugural week of events.”

Attendees can expect tech and startup showcases, panels, pitches, discussions, and networking events to be hosted across Houston and at the Ion, Rice's innovation hub in Midtown. More details on the events will be added to the Ion's website as they become available.

“We look forward to the opportunity to highlight talented founders and connect them with investors, industry practitioners and university resources to help accelerate energy innovation,” Dale Winger, managing director of Halliburton Labs, says in the release. “The collaboration to launch Energy and Climate Startup Week reflects how Houston works together to scale solutions."

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New UH survey reveals concerns over AI data center growth in Houston

data findings

A new report out of the University of Houston shows that area residents remain wary of the long-term effects of operating data centers.

The recent survey from the University of Houston’s latest SPACE City Panel, conducted by the Center for Public Policy at the Hobby School of Public Affairs, shows that while 85 percent of Houston-area residents use AI, nearly 63 percent oppose the construction of AI data centers within 1 mile of their homes.

Respondents’ concerns centered around data centers’ high energy demand and the area’s power grid reliability. According to the survey, 32 percent of residents who oppose local data center projects would be more likely to support the centers if they relied on renewable energy over fossil fuels.

“Respondents understand that AI can bring economic and educational benefits, but they are also concerned about the physical infrastructure needed to fuel AI, especially data centers,” Soran Mohtadi, post-doctoral fellow at the Hobby School and a researcher on the report, said in a news release. “This physical infrastructure demands more electricity and water, leading to environmental impacts.”

Experts estimate that 6.5 gigawatts of data center capacity will be added to the Texas grid by 2030. And Houston’s data center capacity is predicted to more than double by 2028.

The Electric Reliability Council of Texas also projects electricity demand could reach 218 gigawatts by 2031, which would be more than double the record peak set in August 2023. Data centers are expected to account for 86 gigawatts of that new demand.

Survey respondents also said they are concerned about the state's future water supply, given the large amounts of water that data centers need to stay cool.

In terms of who’s responsible for that issue, 57.6 percent of respondents said they put the onus on Texas lawmakers, while 31.5 percent say tech companies should be responsible.

Additionally, more than 75 percent of respondents believed that data center developers and technology companies—not residents—should bear the cost of infrastructure upgrades to support data centers.

“Every decision legislators make has implications on residents’ everyday lives and local infrastructure now and in the future,” Maria P. Perez Arguelles, lead researcher on the report and research assistant professor at the Hobby School, added in the news release. “This issue is going to become more important in years to come, so this is just the beginning.”

Read the full report here.

Houston-born Cemvita makes breakthrough in sustainable fuel production

clean fuels

Houston-based biotech company Cemvita announced that it recently reached a critical milestone in the development of its FermOil product, which can be used to create Sustainable Aviation Fuel (SAF) and other renewable fuels at industrial scale.

The company shared in a news release that it completed a 75,000-liter industrial fermentation run at Belgium's Bio Base Europe Pilot Plant.

The campaign achieved target technical metrics for the production of FermOil, Cemvita’s renewable natural oil (RNO). FermOil is produced from industrial crude glycerin, an industrial byproduct, as opposed to traditional sugar-based feedstocks used in many bio-oil fermentation processes. It's designed to be a drop-in feedstock for creating SAFs.

Cemvita had previously advanced its FermOil production process through multiple scale-up stages before successfully reaching the 75,000-liter demonstration campaign, according to the company.

“This is not just a fermentation milestone,” Moji Karimi, CEO at Cemvita, said in the release. “It is a blueprint for how existing industrial infrastructure can evolve into circular bioeconomy infrastructure. Every biodiesel plant generating crude glycerin is a potential platform for renewable natural oil production.”

The milestone also supports the deployment of Cemvita’s industrial biomanufacturing platform, FermWorks, which integrates with existing energy and industrial infrastructure to turn waste carbon streams into SAFs and other materials. According to the release, Cemvita plans to move forward with commercial deployment discussions with partners in Brazil, Europe and in the UK. Cemvita already has a partnership with the Brazilian sustainable research institution REMA.

“We are proud to support innovative companies like Cemvita in scaling breakthrough industrial biotechnology solutions,” Hendrik Waegeman, head of business operations at Bio Base Europe Pilot Plant, added in the release. “Successfully operating at the 75,000-liter scale using a feedstock such as crude glycerin highlights both the maturity of the technology and the quality of the scale-up execution achieved by the Cemvita team.”

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Eli Lilly scoops up Houston biotech startup in $300 million deal

big pharma deal

Pharmaceutical giant Eli Lilly has acquired Houston biotech startup CrossBridge Bio, which develops antibody-drug conjugates for cancer, in a deal worth up to $300 million. The deal was celebrated by TMC Venture Fund and the University of Texas Health Science Center at Houston last week.

CrossBridge, founded in 2023, is developing ADCs based on research by Kyoji Tsuchikama and Zhiqiang An, both of UT Health Houston. Tsuchikama is an associate professor of medicinal chemistry and a globally recognized ADC pioneer, and An is a professor of molecular science and vice president of drug discovery.

Antibody-drug conjugates (ADCs) are a potent combination of targeted therapy and chemotherapy that kills cancer cells while saving healthy tissue.

Clinical trials for CrossBridge’s primary ADC candidate, CBB-120, are expected to start this year, pending approval from the U.S. Food and Drug Administration (FDA).

“I’m proud of how well our team has executed and advanced our platform in such a short time since the company’s founding,” Michael Torres, co-founder and CEO of CrossBridge, said in a news release. “By becoming a part of Lilly, a leader in patient-focused therapeutic development, we are well-positioned to further accelerate the clinical potential of this approach.”

Under the Lilly deal, CrossBridge shareholders were expected to receive an upfront payment along with a follow-up payment based on the achievement of certain milestones.

In 2024, CrossBridge closed a $10 million seed round. Among the investors in CrossBridge are the Texas Medical Center Venture Fund, CE-Ventures, Alexandria Venture Investments, Portal Innovations, Linden Lake Labs, and the Cancer Prevention and Research Institute of Texas (CPRIT). It was formed in TMC Innovation’s Accelerator for Cancer Therapeutics program."Built within the TMC ecosystem, CrossBridge Bio grew with the support, funding, and resources that helped shape its trajectory. TMC led the company's early financing and watched it evolve from its earliest days to its acquisition by Eli Lilly," William McKeon, president and CEO of the Texas Medical Center, shared in a LinkedIn post. "[This is a] strong reminder that breakthrough science and the right early backing can change what’s possible."