Did you know that you can order an eco-conscious burger in Houston? Photo courtesy of Hopdoddy

Hearty Austin-based chain Hopdoddy Burger Bar has unveiled a new lineup of regenerative burgers that are supposed to be better for the planet and the consumer.

The term "regenerative burger" could cause a few head-scratches: Some may think of lab-grown or 3D-printed meat, while others think of plant-based alternatives but it’s neither. It is grass-fed meat, sourced a bit differently. "Regenerative farming" is a term used to describe farming and grazing practices that claim to restore and rebuild degraded soil, resulting in better-quality air and water.

Hopdoddy’s vice president of culinary Matt Schweitzer explained that it all began with with a sense of obligation to do better as a brand for the consumers and the ecosystem.

“We felt like we could really take a stand and look to move our entire supply chain in a regenerative fashion, so we could really be proud of the work we’ve done and we could hopefully leave the animals, the farmers, the ranchers, the native grasslands, and our planet a better place than before we started,” says Schweitzer.

The new menu items include the "Roosevelt Burger" with grass-fed regenerative bison; the "Nashville Hot Sandwich" with regenerative raised chicken; the "Regenerative Royale," which is a play on a classic double quarter-pounder with cheese; the "Mother Nature" with grass-fed regenerative beef; and the "Buffalo Bill" also uses regenerative bison, but appears not to be grass-fed.

The five burgers are available at all Hopdoddy locations nationwide. The beef and bison are sourced from Texas-based regenerative company Force of Nature, while the chicken is from Cooks Venture.

With this launch, Hopdoddy removes all plant-based meat substitutes from its menu, significantly reducing the options for vegans and vegetarians. The company felt the ingredients and ethos of the alternative meats — describing some such as Beyond Meats as "falsely advertised" regarding nutrition in a press release — no longer aligned with its values and mission. However, the house-made veggie patty remains on the signature "El Bandito" burger.

Schweitzer says the regenerative burgers have received positive feedback, as people are excited to know where their food comes from, how it gets to their table, and what type of impact it causes. Regarding the future of regenerative meat, he says there is no doubt it could become mainstream soon.

“I think the flavor profile, the eating experience, the story, the mission, the purpose, really speaks for itself," says Schweitzer. "So, I really think it’s a matter of time until 'regenerative' is talked about in the same way that 'organic,' or 'sustainable,' or those type of buzzwords are talked about."

To further show its commitment to regenerative agriculture, Hopdoddy is also one of the sponsors of Common Ground, a documentary about the pioneers of the regenerative movement, premiering October 4 in Austin. The "uplifting" film, according to a release, features well-known actors Laura Dern, Rosario Dawson, Jason Momoa, Woody Harrelson, Ian Somerhalder, and Donald Glover, emphasizing that this motley crew does share one thing in common: a strong belief in regenerative agriculture.

For more information about the new regenerative burgers, visit hopdoddy.com.

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This article originally ran on CultureMap.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.