Houston expert: How to navigate the innovation journey — from PoC to MVP

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This Houston expert describes the main phases central to any innovation journey. Photo courtesy of Slalom

As a technologist, one thing I learned early in my career about the technology landscape is its constant improvements and I understood that companies who kept up with those changes remain successful and competitive. However, only companies mastering a disciplined innovation framework are truly able to harness the power of emerging tech to help them solve their most complex business challenges.

Innovative solutions come in all shapes and sizes, but not all of them should come to life. Specifically, when considering digital solutions, there are a few widely accepted innovation approaches in the product engineering field. This quick guide describes the main phases central to any innovation journey.

Feasibility Study

Ideating can be fun but executing a feasibility study will ground you on what will work and what may still be science fiction. The thought here is to spend two to four weeks doing research and talking to experts to answer a few key questions that will help you determine the feasibility of your idea or concept. Through the study, you will learn how to look at it from both a technology and a business perspective. More importantly, to answer the question 'Is it even possible to accomplish your goal with this technology?'

A subject matter expert (SME) will quickly tell you yes or no and why. If you find the technology is indeed suitable, then you will move on to evaluate the business feasibility. Does it make financial sense? Does it work within established business policies? Will there be a healthy Return On Investment (ROI) within an acceptable timeline? If you find positive responses to those questions, then you should feel confident to move on to a Proof of Concept (PoC) or even jump to a Minimum Viable Product (MVP). On the other hand, if either the technology is not feasible or the solution doesn't make business sense, then you've just saved yourself a lot of time, budget, and possibly headaches.

Proof of Concept

This phase is about testing the theory and proving the hypothesis, technically speaking. You'll need to go through a Proof of Concept if the technology solution you have in mind hasn't been tested in either a lab setting or in the field. Thinking outside of the box and innovating is all about trying new approaches and solving problems in a novel way, so you'll have to spend the time and budget ensuring it will work as expected. However, you must be very careful to not get carried away.

A proper PoC should take four to six weeks, max. It should help you quickly determine whether the technology will live up to its promise or if you need to pivot to another approach. Building a team with the right skillset is vital to this process because they are the ones evaluating the proposed solution and comparing it to the expected outcomes. Any signs of discord should empower the team to stop the project, saving further investment, and should help you decide if another approach is even possible. If all criteria has been met, then move on to the MVP stage.

Minimum Viable Product

At this point, you have confirmed the solution you imagined works and you are ready to unlock its potential. But you must start small. You must prioritize all the features you want this product to have and decide what the core functionality should be. This is important because if you choose too many features to start with, you may initially spend too much money and time and may even miss a window of business opportunity you may have lined up. Hence the name of the MVP, it is a product that employs the minimum time, money, and features while still being a viable product.

In summary, if you have an innovative idea for a technology solution, I recommend you first determine whether it's feasible, both technology and business wise, through a short and focused study. If feasible, then you can put that concept to the test through a PoC and determine its desirability. If this product is indeed desirable, then moving into building an MVP will help you understand its viability – and that is how you can successfully innovate while keeping risks at bay.


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Alfredo Arvide is the director for the products and innovation practice at Slalom Consulting in Houston, where he helps clients solve their most complex business challenges by leveraging emerging technologies and applying innovative technology solutions.

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Pharma giant considers Houston for $1B manufacturing campus

in the works

Another pharmaceutical giant is considering Houston’s Generation Park for a manufacturing hub.

According to a recent filing with the Texas Jobs, Energy, Technology and Innovation (JETI) program, Bristol Myers Squibb Co. is considering the northeast Houston management district for a new $1 billion multi-modal pharmaceutical manufacturing campus.

If approved, the campus, known as Project Argonaut, could create 489 jobs in Texas by 2031. Jobs would include operations technicians, engineering roles, administrative and management roles, production specialists, maintenance support, and quality control/assurance. The company predicts annual average wages for these positions to be around $96,000, according to the filing.

The project currently includes the 600,000-square-foot facility, but according to the filing, Bristol Myers Squibb “envisions this site growing in scale and capability well beyond its opening configuration."

The Texas JETI program offers companies temporary school property tax limitations in exchange for major capital investment and job creation. E.R. Squibb & Sons LLC applied for a 10-year tax abatement agreement in the Sheldon Independent School District.

The agreement promises a $ 1 billion investment. Construction would begin in 2027 and wrap in 2029.

“The proposed project reflects [Bristol Myers Squibb Co.’s] enduring commitment to bringing innovative medicines to patients and ensuring the long-term supply reliability they depend on,” the filing says. “The proposed project is purpose-built to support and manufacture medicines spanning multiple therapeutic areas and modalities, positioning the site as a long-term launch and commercial campus for decades to come. These medicines will provide therapies to the [Bristol Myers Squibb Co.’s] patients located in markets both nationally and internationally.”

The Fortune 100 company is considering 16 other cities for the new manufacturing facility in the Central and Eastern markets in the U.S. According to the Houston Chronicle, Bristol Myers Squibb Co is still in the “evaluation process” for its potential manufacturing site.

Last fall, Eli Lilly and Co. selected Generation Park for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.

Houston health tech co. lands NIH grant for AI cancer prediction tool

fresh funding

Houston-based CellChorus and Stanford Medicine were recently awarded a Phase I Small Business Innovation Research grant for the company's AI platform to test how certain cancer patients will respond to therapies.

The funding comes from the National Cancer Institute of the National Institutes of Health. According to a filing, the grant totaled just under $400,000.

CellChorus, which spun out from the University of Houston’s Technology Bridge, has developed TIMING (Time-lapse Imaging Microscopy In Nanowell Grids), which analyzes the behavior of thousands of individual immune cells over time and can identify early indicators of treatment success or failure.

The company will work with Stanford's Dr. David Miklos and Dr. Saurabh Dahiya, who have built the Bone Marrow Transplantation and Cell Therapy Biobank. The biobank manages and stores biological samples from patients treated at their clinic and in clinical trials.

"Predicting which patients will achieve durable responses after CAR-T therapy remains one of the most important challenges in the field,” Miklos said in a news release. “We aim to uncover functional cellular signatures that can guide treatment decisions and improve patient outcomes.”

The project will specifically profile cells from patients with relapsed/refractory large B-cell lymphoma (r/rLBCL). According to CellChorus, only about half of r/rLBCL patients who receive CAR-T therapy "achieve a durable, long-term remission." Others do not respond to therapy or experience relapse.

“The sooner we know whether a cancer therapy is working, the better. To maximize patient benefit, we need technology that can provide a robust and early prediction of response to therapy. The technology needs to be scalable, cost-efficient, and capable of rapid turnaround times,” Rebecca Berdeaux, chief scientific officer of CellChorus, added in the release. “We are excited to work with Drs. David Miklos and Saurabh Dahiya and their colleagues on this very important project.”

CellChorus has previously received SBIR grants from federal agencies, including a $2.5 million award in 2024 from its National Center for Advancing Translational Sciences (NCATS) and a $2.3 million SBIR Fast-Track award from the National Institute of General Medical Sciences in 2023.

Houston museum showcases America's founding documents in rare exhibit

Experience History

As the United States prepares to celebrate its 250th birthday, Houstonians have a chance to see rare documents from the founding of the nation. Freedom Plane National Tour: Documents That Forged a Nation, presented by the National Archives Foundation, will be on display at the Houston Museum of Natural Science through Monday, May 25.

The collection includes a rare engraving of the original Declaration of Independence; official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton; a draft of the Bill of Rights; the Treaty of Paris, the documented that recognized America's independence from Great Britain; and the tally of votes approving the Constitution.

The National Archives specifically chose Houston as one of only eight cities in the country to host the exhibit as a means to help the documents reach a wider audience outside of the main hub of semiquincentennial events in New England and the Washington, D.C. area.

"One of the things we decided when we put the tour together because we wanted to be off the East Coast," said Patrick Madden, CEO of the National Archives Foundation, who was onsite for the exhibit's opening in Houston. "There's a lot of 250th celebration stuff happening in the original 13 colonies. How do we get it to major markets where larger numbers of people can see it? So in the case of Houston, obviously, [is a] major market in this part of the country, but also we've partnered with the museum twice before with National Archives exhibits, so we knew that they would be up to the task of handling the exhibit and the crowds."

The star of the collection is a rare engraving of the original Declaration of Independence. Secretary of State and future president John Quincy Adams commissioned 200 exact replicas of the document from engraver William J. Stone in 1823. Less than 50 now remain. Madden joyfully pointed out that there are errors in this document, a potent reminder that the men who forged a nation made mistakes.

"There's a couple of typos in it where they had to make corrections," said Madden. "So even the founders, you know, they're all human. That resonates because here these people are making this move against the most powerful nation in the world and putting their lives on the line for a country based on ideas."

Other impressive parts of the collection include official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton, as well as one of the drafts of the Bill of Rights. Many states would not ratify the Constitution until certain rights were included in the document, leading to Washington going on a national tour assuring state leaders enshrining protections was first on the list. The draft copy on display specifically shows the First Amendment in progress.

Houston is the fourth stop on the exhibition's tour, which will take the documents to Denver, Miami, Dearborn, and Seattle through the summer. Freedom Plane is just one part of a larger patriotic celebration at the HMNS, which includes a film series celebrating American science and culture and general Americana decoration throughout the main hall.

Admission to Freedom Plane is free to the public, but separate from general admission to the museum. Space is limited, and passes are available on a first-come, first-serve basis. Non-members should expect long waits or the possibility that the day's passes are sold out. Only museum members can reserve passes for specific times. Flash photography is prohibited due to the fragile nature of the documents.

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This article originally appeared on CultureMap.com.

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