The Sierra AppHaus Houston plans to host design-thinking workshops, tech discussions and hackathons. Photo via apphaus.sap.com

Houston’s Sierra Digital has launched Sierra AppHaus Houston, an innovation hub for business AI in collaboration with the the AppHaus program from software giant SAP.

Sierra Digital is the second U.S. partner to join the SAP AppHaus Network, a group of spaces focused on leveraging SAP products and technology. The operation is connected to Sierra Digital’s offices in the Sharpstown area. It features three meeting rooms and a large conference room, and can host workshops for more than 100 participants.

“Sierra Digital has been recognized as a perfect addition to the SAP AppHaus Network,” Carlos Estala Velasco, co-lead SAP AppHaus Partner Network, said in a news release. “With a committed AppHaus team equipped to apply our award-winning human-centered innovation approach, they are able to inspire and support customers throughout their journey to realize innovation. We eagerly anticipate co-innovating with the local team!”

Sierra Digital, founded in 2002, focuses on modernizing legacy SAP systems. It has developed a library of over 30 pre-built business technology applications (BTA) and is also one of the first SAP partners to develop and implement use cases for business AI. The company is also a leading member of the SAP BTP Advisory Council.

Sierra’s portfolio of pre-built BTP applications helps streamline operations by automating tasks like business partner onboarding and revenue processing with AI-driven insights. The company works in the oil and gas, chemical, manufacturing, retail and public sectors.

The first SAP AppHaus location was established in 2013, and there are now 25 globally. Three of the locations are owned by SAP, and 22 are managed by partners, including Sierra Digital. According to a LinkedIn post, Sierra Digital plans to use the Houston space for design-thinking workshops, tech discussions and even hackathons.

"We are proud to be part of the SAP AppHaus Network and to contribute our design and innovation expertise," Senthil Kumar, CEO and chairman of Sierra Digital, said in a news release. "This collaboration with SAP allows us to co-create impactful solutions that accelerate digital transformation for our clients and strengthen our regional presence."

Meet the latest global health tech startups to get an invite to Houston from TMC Innovation. Photo via tmc.edu

12 health tech startups named to Houston accelerator's next bootcamp

onboarding

Twelve promising health tech startups have been selected for the annual bootcamp at the Texas Medical Center.

TMC's Accelerator for HealthTech selected 12 companies from around the world and across specialties for the opportunity. Following the bootcamp, TMC will move forward a selection of startups to join its accelerator.

"Houston, a thriving hub for innovation, is rapidly becoming the destination of choice for healthtech companies," reads a statement from TMC. "With the Texas Medical Center at its heart, the city offers unparalleled resources, cutting-edge research facilities, and a collaborative spirit that fosters growth. This environment not only attracts startups but also provides them with the necessary tools to navigate the complex landscape of healthcare commercialization."

Through the bootcamp, the participants will engage with advisors and industry experts, refine their business models, prepare for market entry, and have opportunities for collaboration with the TMC's member organizations.

The selected bootcamp companies, according to TMC, include:

  • Alyf, founded in Newport Beach, California, has developed a personalized cardiac care system that brings patients and providers together with real-time, AI-driven insights, enabling them to monitor, track, and improve cardiac health outcomes collaboratively.
  • Seoul, South Korea-based Deepmetrics leverages artificial intelligence to provide ICU smart care services that optimize medical device settings, such as mechanical ventilators, to reduce mortality and shorten the length of stay for critically ill patients worldwide.
  • Equity Quotient, from New York City, is a healthcare intelligence platform that automates compliance and provides actionable insights by aggregating public, private, and first-party data, using proprietary analytics to help leaders address disparities, improve outcomes, and lower care costs.
  • Also from New York City, Ethermed's AI-powered solution streamlines prior authorizations, eliminating up to 90 percent of auths and 70 percent of the labor involved. Ethermed requires no workflow changes, is fully auditable, and offers aligned incentives from a mission-driven, human-focused company.
  • Fibricheck, based in Hasselt, Belgium, transforms ordinary smartphones into regulated digital heart rhythm monitors, offering unparalleled access to cardiovascular diagnostics for patients and streamlined workflows for physicians.
  • Austin-based NearWave has developed a non-invasive, AI-powered handheld imaging device that can predict breast cancer therapy response within seven days.
  • Pragmaclin, founded in Newfoundland, Canada, developed a cutting-edge PRIMS (Parkinson’s Remote Interactive Management System) that leverages depth cameras and machine learning to monitor and assess Parkinson’s Disease symptoms, offering healthcare professionals remote and in-clinic insights to enhance treatment decisions.
  • Somnair, a Baltimore, Maryland, company, is developing a non-invasive neurostimulation oral appliance for treating obstructive sleep apnea, offering a sleek, retainer-sized device that provides an effective alternative to CPAP or invasive surgery for millions of patients.
  • Vancouver, Canada-headquartered Total Flow Medical is developing solutions to enhance the quality of care and life for patients requiring the use of a heart-lung machine during surgery or life support.
  • Tympulse, hailing from Dublin, Ireland, is commercializing TympanoColl, an innovative and disruptive solution for eardrum (Tympanic Membrane) repair in an outpatient setting through the ear canal.
  • Perth, Australia-based Vital Trace is developing a continuous lactate monitor for real-time, accurate detection of fetal distress.
  • New York City's WorkUp is a healthcare-specific talent pipeline management platform that connects students with tailored resources for their clinical career journey, providing personalized support as their needs evolve.
Energy Tech Nexus has opened in downtown Houston. Photo by Natalie Harms/EnergyCapital

New downtown Houston hub opens to support energy transition innovators

now open

Three Houston energy innovators have cut the ribbon on a new space for energy transition innovation.

The Energy Tech Nexus, located in the historic Niels Esperson Building at the corner of Travis and Rusk Avenue, opened on September 10, which was proclaimed Energy Tech Nexus Day by the city.

Jason Ethier and Juliana Garaizar, formerly in leadership roles at Greentown Labs, teamed up with Nada Ahmed, previously headed innovation and transformation at Aker Solutions, launched ETN as a community for energy transition startups. The new hub plans to host incubation programs, provide mentorship, and open doors to funding and strategic partnerships for its members.

"We are creating more than a space for innovation," Garaizar, who serves as CEO of ETN, says in a news release. "We are crafting a community where pioneers in technology and energy converge to challenge the status quo and accelerate the shift to sustainable energy solutions."

The hub describes its goal of tackling the "trilemma" of energy security, sustainability, and affordability while also contributing to the mission of setting up Houston as the global center for energy transition. To accomplish that mission, ETN will help facilitate rapid deployment of cutting-edge energy technologies.

'The future of energy is not just being written here in Houston; it's being rewritten in more sustainable, efficient, and innovative ways," adds Garaizar. "Houston provides the perfect backdrop for this transformation, offering a rich history in energy and a forward-looking approach to its challenges and opportunities."

"We believe that a broad spectrum of perspectives is crucial in solving global energy challenges. It's about bringing everyone to the table — startups, industry leaders, and investors from all backgrounds," she continues.

Ethier, who co-hosts the Energy Tech Startups Podcast with Ahmed, says he hopes that ETN acts as a meeting place for energy transition innovators.

"By providing the right tools, access, and expertise, we are enabling these companies to leap from ideation to implementation at an unprecedented pace;" Ethier explains. "The interaction between startups and established companies within Energy Tech Nexus creates a unique synergy, fostering innovations that might otherwise take years to mature in isolation."

Payal Patel, an angel investor who has held leadership roles at Station Houston, Plug and Play Ventures, and Softeq, also contributed to launching ETN, which is collaborating with George Liu, who has over 15 years of investment banking experience across energy, cleantech and hardtech with more than $20 billion in M&A projects across his career.

In May, ETN teamed up with Impact Hub Houston to establish the Equitable Energy Transition Alliance and Lab to accelerate startup pilots for underserved communities. The initiative announced that it's won the 2024 U.S. Small Business Administration Growth Accelerator Fund Competition, or GAFC, Stage One award.

ETN celebrated its opening during the inaugural Houston Energy and Climate Week.

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This article originally ran on EnergyCapital.

Introducing the Rice Nexus. Rendering courtesy of Rice University

Rice University reveals details of collaborative hub expected to open in the Ion later this year

coming soon

Rice University is going beyond the hedges with its hub at the Ion, for which the school has just details and renderings.

For over a year, Rice has been planning its Rice Nexus, a collaborative hub for the university's innovation efforts located in the Ion District, Rice Management Company's 16-acre district in Midtown. Expected to open this fall, the new space will be located across 10,000 square feet on two floors of the Ion.

“We believe in the power of innovation to transform lives and shape the future,” Rice President Reginald DesRoches says in a news release. “With the launch of the Rice Nexus at the Ion, we are embarking on a journey to unleash the full potential of Houston’s innovation ecosystem, driving positive change and rapid economic growth.”

Rendering courtesy of Rice University

The Rice Nexus will provide the university's community with prototyping tools, access to venture capital opportunities, and entrepreneurial support.

“We are thrilled to introduce the Nexus so that our faculty and students can rapidly develop, derisk and deploy solutions into the world by harnessing the full resources and capabilities of the Ion District,” Paul Cherukuri, Rice’s chief innovation officer, adds. “Houston is a grand city of innovation, and the Nexus at the Ion further amplifies Rice as a global leader in inventing and commercializing world-changing technology at both speed and scale.”

Rice reports that three startups founded by faculty — Solidec, Coflux Purification, and DirectH2 — will be located in the facility.

“The critical support provided through the Nexus highlights Rice’s leadership in pioneering essential hard tech development in the middle of the world’s energy capital, revolutionizing the country’s next-generation clean energy and chemical manufacturing technologies while fostering the next generation of innovators in energy sustainability,” says DirectH2 Co-Founder Aditya Mohite, professor of chemical and biomolecular engineering, electrical and computer engineering and materials science and nanoengineering.

Rendering courtesy of Rice University

The new building is supposed to deliver in 2026. Rendering via UH.edu

Houston business leaders make donation to rising innovation hub, establish economic inclusivity initiative

supporting students

Two University of Houston alumni have made a donation supporting a project that will create a central campus hub for innovation activity.

Ali and Emad Lakhany, along with their family, have reportedly donated to their alma mater to support the University’s planned Innovation Hub. The amount of the donation was not disclosed but also contributed to economic inclusivity research at the C. T. Bauer College of Business, according to a UH news release, by establishing the Musa and Khaleda Dakri Center for Economic Inclusion.

With the gift, UH will name the second floor of the building the Salma and Hashim Yousuf Lakhany Entrepreneurship Floor, in honor of the brothers' parents who emigrated from Pakistan in the 1960s.

"My brother Emad, sister Lina, and I are thrilled to make this generous gift to the Bauer College of Business and the University of Houston’s innovation and entrepreneurship initiatives,” says CSM Group CEO Ali Lakhany, a 2007 UH graduate, in the release.

The CSM Group is a Houston company that works in restaurant franchising, telecommunications, hospitality, and real estate development.

“Our parents, immigrants to this country, have always instilled in us a profound belief in the power of entrepreneurship and the importance of giving back. With this contribution towards the Innovation Hub, we are honored to have a floor named after our parents within this remarkable building,” he continues. “We are excited about the boundless opportunities this space will offer to students, entrepreneurs and innovators. Together, we look forward to a future of endless possibilities and positive impact."

Originally reported about by InnovationMap, the UH Innovation Hub is a 75,000 square-foot building to rise on the site of the current Technology Annex building and open in 2026. In it will reside the Cyvia and Melvyn Wolff Center for Entrepreneurship, the Musa and Khaleda Dakri Center for Economic Inclusion, the Energy Transition Institute, a large makerspace, and more.

Ali Lakhany and Emad Lakhany are UH alumni. Photo via uh.edu

The Alexandria Center for Advanced Technologies at The Woodlands is open for business. Rendering courtesy of Alexandria Real Estate Equities

Developer delivers 120,000-square-foot life science innovation hub to The Woodlands

now open

A new innovation hub mega campus has opened in The Woodlands.

The Alexandria Center for Advanced Technologies at The Woodlands comes courtesy of California-based Alexandria Real Estate Equities Inc. The campus is home to the first purpose-built, cost-effective Class A laboratory infrastructure in the Houston suburb.

The campus takes advantage of Alexandria’s cluster model, which is informed by the cluster theory of business created by Harvard Business School’s Michael E. Porter. The belief behind the cluster is that there are four critical drivers necessary to creating a thriving business cluster: location, innovation, talent and capital. With nearly three decades of creating such STEM ecosystems, Alexandria is well positioned to grow something important in The Woodlands.

The campus’ first building is a 123,392-square-foot, LEED Gold Core and Shell, and Fitwel-certified redevelopment project. One of the initial tenants in that building is Nurix Therapeutics, a San Francisco-based clinical-stage biopharmaceutical company.

“We have had an outstanding strategic relationship with Alexandria since 2014 and approached them to support our expansion to Texas,” Arthur T. Sands, MD, PhD, president and chief executive officer of Nurix said in a press release. “The Woodlands offers us a business-friendly, entrepreneurial environment that is critical to our growth. Alexandria’s thoughtfully designed new campus provides us with state-of-the-art laboratory space and dynamic amenities that are key to helping us attract and retain top talent as we work to change the future of medicine through an exciting new modality of treating disease: targeted protein modulation.”

Nurix’s focus is treating cancer and other challenging diseases using protein modulation. Its expansion to the Houston area will help the company to build both proprietary and partnered programs in oncology as well as autoimmune and inflammatory diseases.

“Our efforts in The Woodlands are much like when we entered New York City, where commercial life science was very limited before we opened our flagship Alexandria Center for Life Science – NYC in 2010,” Joel S. Marcus, executive chairman and founder of Alexandria Real Estate Equities, Inc. and Alexandria Venture Investments, says in a news release. "We are similarly committed to developing a commercial life science presence in The Woodlands.

"Steve Jobs once said, ‘the biggest innovations of the twenty-first century will be at the intersection of biology and technology,’ and his prediction has come to fruition," Marcus continues. "Here in The Woodlands, this important convergence will drive opportunities to accelerate the development of new medicines to benefit patients."

Care for a round of pickleball with a colleague? The Alexandria Center for Advanced Technologies campus is replete with appealing with amenities. They indeed include onsite pickleball courts, but also modern conference and event space; an large, welcoming courtyard and event lawn; and a wellness and fitness center so innovators can keep their bodies as healthy as their minds.

With the objective of further driving this STEM ecosystem, the company is also bringing the Alexandria Seed Capital Platform to The Woodlands. The nationwide platform unites leaders from across the life science community to catalyze early-stage investment in life science companies. If Alexandria’s goals come to fruition, more medical companies may soon be heading to Houston’s ‘burbs.

The Alexandria Center for Advanced Technologies at The Woodlands

Image courtesy of Alexandria Real Estate Equities

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Houston biotech co. raises $11M to advance ALS drug development

drug money

Houston-based clinical-stage biotechnology company Coya Therapeutics (NASDAQ: COYA) has raised $11.1 million in a private investment round.

India-based pharmaceuticals company Dr. Reddy’s Laboratories Inc. led the round with a $10 million investment, according to a news release. New York-based investment firm Greenlight Capital, Coya’s largest institutional shareholder, contributed $1.1 million.

The funding was raised through a definitive securities purchase agreement for the purchase and sale of more than 2.5 million shares of Coya's common stock in a private placement at $4.40 per share.

Coya reports that it plans to use the proceeds to scale up manufacturing of low-dose interleukin-2 (IL-2), which is a component of its COYA 302 and will support the commercial readiness of the drug. COYA 302 enhances anti-inflammatory T cell function and suppresses harmful immune activity for treatment of Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s disease and Alzheimer’s disease.

The company received FDA acceptance for its investigational new drug application for COYA 302 for treating ALS and FTD this summer. Its ALSTARS Phase 2 clinical trial for ALS treatment launched this fall in the U.S. and Canada and has begun enrolling and dosing patients. Coya CEO Arun Swaminathan said in a letter to investors that the company also plans to advance its clinical programs for the drug for FTD therapy in 2026.

Coya was founded in 2021. The company merged with Nicoya Health Inc. in 2020 and raised $10 million in its series A the same year. It closed its IPO in January 2023 for more than $15 million. Its therapeutics uses innovative work from Houston Methodist's Dr. Stanley H. Appel.

New accelerator for AI startups to launch at Houston's Ion this spring

The Collectiv Foundation and Rice University have established a sports, health and wellness startup accelerator at the Ion District’s Collectiv, a sports-focused venture capital platform.

The AI Native Dual-Use Sports, Health & Wellness Accelerator, scheduled to formally launch in March, will back early-stage startups developing AI for the sports, health and wellness markets. Accelerator participants will gain access to a host of opportunities with:

  • Mentors
  • Advisers
  • Pro sports teams and leagues
  • University athletics programs
  • Health care systems
  • Corporate partners
  • VC firms
  • Pilot projects
  • University-based entrepreneurship and business initiatives

Accelerator participants will focus on sports tech verticals inlcuding performance and health, fan experience and media platforms, data and analytics, and infrastructure.

“Houston is quickly becoming one of the most important innovation hubs at the intersection of sports, health, and AI,” Ashley DeWalt, co-founder and managing partner of The Collectiv and founder of The Collectiv Foundation, said in a news release.

“By launching this platform with Rice University in the Ion District,” he added, “we are building a category-defining acceleration engine that gives founders access to world-class research, global sports properties, hospital systems, and venture capital. This is about turning sports-validated technology into globally scalable companies at a moment when the world’s attention is converging on Houston ahead of the 2026 World Cup.”

The Collectiv accelerator will draw on expertise from organizations such as the Rice-Houston Methodist Center for Human Performance, Rice Brain Institute, Rice Gateway Project and the Texas Medical Center.

“The combination of Rice University’s research leadership, Houston’s unmatched health ecosystem, and The Collectiv’s operator-driven investment platform creates a powerful acceleration engine,” Blair Garrou, co-founder and managing partner of the Mercury Fund VC firm and a senior adviser for The Collectiv, added in the release.

Additional details on programming, partners and application timelines are expected to be announced in the coming weeks.

4 Houston-area schools excel with best online degree programs in U.S.

Top of the Class

Four Houston-area universities have earned well-deserved recognition in U.S. News & World Report's just-released rankings of the Best Online Programs for 2026.

The annual rankings offer insight into the best American universities for students seeking a flexible and affordable way to attain a higher education. In the 2026 edition, U.S. News analyzed nearly 1,850 online programs for bachelor's degrees and seven master's degree disciplines: MBA, business (non-MBA), criminal justice, education, engineering, information technology, and nursing.

Many of these local schools are also high achievers in U.S. News' separate rankings of the best grad schools.

Rice University tied with Texas A&M University in College Station for the No. 3 best online master's in information technology program in the U.S., and its online MBA program ranked No. 21 nationally.

The online master's in nursing program at The University of Texas Medical Branch in Galveston was the highest performing master's nursing degree in Texas, and it ranked No. 19 nationally.

Three different programs at The University of Houston were ranked among the top 100 nationwide:
  • No. 18 – Best online master's in education
  • No. 59 – Best online master's in business (non-MBA)
  • No. 89 – Best online bachelor's program
The University of Houston's Clear Lake campus ranked No. 65 nationally for its online master's in education program.

"Online education continues to be a vital path for professionals, parents, and service members seeking to advance their careers and broaden their knowledge with necessary flexibility," said U.S. News education managing editor LaMont Jones in a press release. "The 2026 Best Online Programs rankings are an essential tool for prospective students, providing rigorous, independent analysis to help them choose a high-quality program that aligns with their personal and professional goals."

A little farther outside Houston, two more universities – Sam Houston State University in Huntsville and Texas A&M University in College Station – stood out for their online degree programs.

Sam Houston State University

  • No. 5 – Best online master's in criminal justice
  • No. 30 – Best online master's in information technology
  • No. 36 – Best online master's in education
  • No. 77 – Best online bachelor's program
  • No. 96 – Best online master's in business (non-MBA)
Texas A&M University
  • No. 3 – Best online master's in information technology (tied with Rice)
  • No. 3 – Best online master's in business (non-MBA)
  • No. 8 – Best online master's in education
  • No. 9 – Best online master's in engineering
  • No. 11 – Best online bachelor's program
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This article originally appeared on CultureMap.com.