The panel at the inaugural conference featured Brad Rossacci of Accenture Innovation. Courtesy of INNO

Recently, Brad Rossacci, Accenture's Houston Innovation Hub's disruptive innovationeer and creative director, participated in the inaugural INNO, a conference dedicated to supporting the community of innovators, collaborators, and industry disruptors by providing them with a forum to share knowledge, connect with colleagues from around the world, and identify opportunities to work together.

Brad made the trip to New Orleans not just to speak, but also to see first-hand how Houston's neighboring cities are approaching the ideas, themes, and business best practices he's developing within Accenture and more broadly, within the Houston business community.

Speaking as part of the kickoff keynote, titled "What Corporate Innovators Seek," Brad was joined on stage by Aimee Quirk of InnovationOchsner, Lauren Kenney, vice president of Grid Modernization and Strategy at Entergy, and panel facilitator Chase Langdon, Partnership Strategy Manager for the New Orleans Saints and Pelicans. Seated on the INNO stage, Brad had the ideal spot to both share his own expertise, and to hear first hand about how big businesses are working with startups and entrepreneurs outside of Houston.

During the course of the discussion it became clear that all the panelists and the organizations they represent are on the same page in several important ways: all of these companies have big footprints within their local communities and beyond. All have concluded that the challenges facing their different industries and economic sectors — as well as their organizations specifically— require a broader set of skills, backgrounds, and expertise to work through than can be found within the walls of any single company. And all have come to appreciate that to remain a business leader in an increasingly agile and rapidly transforming world, the work of innovation and problem solving must be approached with intentionality and given enough freedom to move fast enough to keep up and get ahead.

They also differ in key respects. The companies represented did not all arrive at these conclusions at the same time. Accordingly, their innovation initiatives are at different stages of development and implementation, both with regard to putting together internal innovation- focused teams and in finding outside companies to partner and collaborate with. Moreover, there are challenges specific to their industries that impact how they pursue their innovation goals. They also face different challenges in terms of getting support from the rest of their organizations. Nevertheless, there have been some challenges that all panelists experienced in some capacity, as well as some agreed-upon best practices.

All agreed that when hiring for internal innovation teams or initiatives, the primary qualification is not a specific set of skills or work history, but rather a specific mindset: they are looking for creative problem solvers who are willing to think and do things differently and who are not intimidated by challenges. Another point they all agreed on is that it's not always easy to find these innovation-oriented people, and that it can be difficult to entice them away from other markets. In particular, the New Orleans based businesses represented expressed feeling the pinch of a limited talent pool.

As the conversation facilitator, Chase Langdon was informed by some of the goals and challenges he's facing as Partnership Strategy Manager for the New Orleans Saints and Pelicans. Reflecting on the structure of the discussion, shared that his team is increasingly cognizant of the potential they have to make an impact on the business community within the region by nurturing holistic economic growth. The Saints and the Pelicans are among the most visible and recognizable local business entities, and his team is actively exploring ways to leverage that visibility to drive growth through partnerships.

Accordingly, his questions reflected an interest in learning from the other organizations represented.

So what are some of the key take away points that Chase and other attendees interested in launching their own innovation initiatives, or in partnering with other organizations? Aimee noted that for those looking to do business with companies like Ocshner, it's important to think about what it takes to be a good partner, not just what it takes to get the deal done. There was general agreement that one of the advantages to working with startups is that they can move quickly as they are less burdened by legacy processes of an older institution.

Similarly, innovators and problem solvers, whether part of internal teams or outside partners, need to be empowered and supported when taking the risks inherent in exploration and experimentation. Brad, in particular, noted that he considers creating an environment that nurtures and protects the "beautiful minds" of his team and the larger Houston innovation ecosystem, to be one of the primary responsibilities of his job.

"Startups are the rockstars now," he says, and existing companies looking to remain competitive need to take a hands-on approach to cultivating a collaborative and sustainable business environment with the required diversity of experiences, perspectives, and skills that lead to breakthroughs.

------

Lizy Freudmann is head of marketing for the INNO.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.