Greentown Labs has announced its newest climatetech incubator cohort. Photo via GreentownLabs.com

Greentown Labs announced that it added five startups to its Houston community in Q1 of 2025.

The companies are among a group of 19 that joined the climatetech incubator, which is co-located in Houston and Boston, in the same time period. The companies that joined the Houston-based lab specialize in a number of "green" applications, from converting plastic waste into sustainable materials to developing energy-storage solutions.

The new Houston members include:

  • Concept Loop, a project of Pakistan-based Innova8e Inc., aims to repurpose post-industrial and post-consumer plastic waste into sustainable building materials.
  • GeoFuels, a Sugar Land-based company that produces hydrogen by using baseload geothermal power and methane pyrolysis.
  • PLASENE, a Houston-based company with an innovative platform that converts plastic waste into liquid fuel and low-carbon hydrogen through its proprietary catalysts and modular, scalable, pre-engineered units platform. The company was named to Greentown's ACCEL Year 3 cohort earlier this year.
  • RepAir Carbon, an Israeli company with a fully electric, zero-heat carbon-removal technology that consumes minimal energy, operates without liquids or solvents, and produces no hazardous materials or waste.
  • RotorVault from Pasadena, California, is commercializing energy-storage and load-following solutions that are containerized, modular, and field-deployable systems built on flywheel technology.

Fourteen other companies will join Greentown Boston's incubator. See the full list here.

PLASENE and five other new members—Thola, Respire Energy, Andros Innovations, FAST Metals and Tato Labs—join Greentown Labs through its most recent Advancing Climatetech and Clean Energy Leaders Program, or ACCEL, cohort. ACCEL, which works to advance BIPOC-led startups in the climatetech space, announced its third cohort last month.

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A version of this story originally appeared on our sister site, EnergyCapitalHTX.

A report by web-hosting company Hostinger showed that Texas is making one of the biggest impacts on the digital economy. Photo via Getty Images

Texas lands top 10 spot in new future of tech study

report

Texas is among the top 10 states making the biggest investments in digital innovation, according to a new study.

The study, conducted by web-hosting company Hostinger, puts Texas in eighth place among the states when it comes to these key metrics:

  • Financial impact of the digital economy
  • Amount of venture capital and grants received by digital startups
  • Number of government-run tech hubs
  • Presence of top-rated business incubators

“To many, the Texas story is one of oil magnates and real estate tycoons. But in recent decades, the state has emerged as an innovation and high-tech hub,” according to a report from the Federal Reserve Bank of Dallas.

On a scale of 1 to 100, Texas received a score of 79. California nabbed the top spot with a score of 100. Appearing behind California and ahead of Texas in the ranking are:

  • No. 2: New York
  • No. 3: Washington
  • No. 4: Illinois
  • No. 5: Massachusetts
  • No. 6: Missouri
  • No. 7: Wisconsin

In terms of ranking factors, Texas benefited the most from landing at No. 2 among the states for its impact on the digital economy. The study pegged Texas’ digital economic impact at $141.7 billion, well below California’s impact of $492.8 billion.

Hostinger relied primarily on government data on 31 states to come up with the ranking. “The research provides a detailed ranking based on a composite score that reflects each state's overall investment and capacity for digital innovation,” the company says.

More than 30,000 businesses in Texas participate in the digital economy, according to the Computer & Communications Industry Association (CCIA). Those businesses employ more than 633,000 people and account for over six percent of the state’s GDP, a key measure of economic strength.

“As technology companies face increasing scrutiny through state and national legislation and litigation, it’s crucial to recognize the significant positive impacts of the digital economy that resonate across the United States,” says the CCIA.

Texas Medical Center Innovation won a Prix Galien Award, which has been described as being comparable to the Nobel Prize for the life science community. Photo by Natalie Harms/InnovationMap

Houston's Texas Medical Center wins prestigious global award recognizing leaders in life science innovation

new bling

Last month, a global organization honored innovation leaders in life sciences, and the Texas Medical Center was among the recipients of the prestigious awards program.

The 18th annual Prix Galien Awards Gala awarded TMC Innovation with the win in the "Incubators, Accelerators and Equity" category. The Galien Foundation created the awards program in 1970 in honor of Galien, the father of medical science and modern pharmacology. Alongside TMC, the other winners represented biotech, digital health, startups, and more.

"We are super proud of this distinction," Tom Luby, director of TMC Innovation says at Envision 2024 last month, crediting the TMCi team and TMC leadership for the award. "We lean on a lot of advisers and experts — people who volunteer their time to work with startups. Without (them), we would not have been successful."

Luby explains that a Prix Galien Award holds a Nobel Prize level of significance for the community.

TMCi was named a finalist in August, and competed against programs from Cedars-Sinai, Mayo Foundation for Medical Education and Research, TechConnect, and more.

"The Awards Committee is honored to witness the exceptional dedication and creativity of our nominees as they turn visionary ideas into transformative solutions for patients worldwide," says Michael Rosenblatt, chair of the Prix Galien USA Awards Committee, in a news release. "Their unwavering commitment to advancing patient care is truly commendable, and we are honored to celebrate their outstanding contributions to global health."

The award is displayed at TMC Innovation's office, located in the medical center at 2450 Holcombe Blvd.

A Houston-based initiative has been selected by the DOE to receive funding to develop clean energy innovation programming for startups and entrepreneurs. Photo via Getty Images

Houston initiative selected for DOE program developing hubs for clean energy innovation

seeing green

Houston has been selected as one of the hubs backed by a new program from the United States Department of Energy that's developing communities for clean energy innovation.

The DOE's Office of Technology Transitions announced the the first phase of winners of the Energy Program for Innovation Clusters, or EPIC, Round 3. The local initiative is one of 23 incubators and accelerators that was awarded $150,000 to support programming for energy startups and entrepreneurs.

The Houston-based participant is called "Texas Innovates: Carbon and Hydrogen Innovation and Learning Incubator," or CHILI, and it's a program meant to feed startups into the DOE recognized HyVelocity program and other regional decarbonization efforts.

EPIC was launched to drive innovation at a local level and to inspire commercial success of energy startups. It's the third year of the competition that wraps up with a winning participant negotiating a three-year cooperative agreement with OTT worth up to $1 million.

“Incubators and Accelerators are uniquely positioned to provide startups things they can't get anywhere else -- mentorship, technology validation, and other critical business development support," DOE Chief Commercialization Officer and Director of OTT Vanessa Z. Chan says in a news release. “The EPIC program allows us to provide consistent funding to organizations who are developing robust programming, resources, and support for innovative energy startups and entrepreneurs.”

CHILI, the only participant in Texas, now moves on to the second phase of the competition, where they will design a project continuation plan and programming for the next seven months to be submitted in September.

Phase 2 also includes two national pitch competitions with a total of $165,000 in cash prizes up for grabs for startups. The first EPIC pitch event for 2024 will be in June at the 2024 Small Business Forum & Expo in Minneapolis, Minnesota.

Last fall, the DOE selected the Gulf Coast's project, HyVelocity Hydrogen Hub, as one of the seven regions to receive a part of the $7 billion in Bipartisan Infrastructure Law. The hub was announced to receive up to $1.2 billion — the most any hub will get.

The DOE's OTT selections are nationwide. Photo via energy.gov

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This article originally ran on EnergyCapital.

Tech startups are leaving Silicon Valley in droves — and some are finding benefits in heading back to school. Miguel Tovar/University of Houston

Siliconned: Leaving Silicon Valley for universities

Houston Voices

Silicon Valley has been a tech startup paradise for decades. It has been described as the modern day Florence in the Renaissance. Tech gods from Apple and Google to Facebook and Twitter were born here. We can credit Silicon Valley as the birthplace for such world-changing innovations like smartphones, microprocessor chips, Tesla automation, and WIFI-enabled teapots.

Okay, so maybe that last one isn't changing the world, but it was created in the Valley and it's changed my life, for whatever that's worth. If Silicon Valley were a country, it would have the 19th-biggest economy on the planet. There's no doubt it is an engineer's dream. A techie's haven. A capitalist's utopia. A beacon of the modern world.

Or at least, it used to be.

Now leaving the Bay Area

There is an exodus in Silicon Valley. It's been happening for about three years. For instance, according to a 2018 poll conducted by the Bay Area Council, 46 percent of survey takers admit they plan to leave the Bay Area in the next year. Couple that with the fact that Silicon Valley investors have allocated 66 percent of their funds into startups outside of Silicon Valley, compared with 50 percent just six years ago, and you have a recipe for a great exodus to other markets around the country.

Now, just for kicks, add to all of this that the Kauffman Foundation's research has pegged Miami-Fort Lauderdale as the number one city in America for startup activity. Where does Silicon Valley's Bay Area, formerly the world's preeminent hub for tech startups, rank? Fourteenth. How the mighty have fallen.

So, to what exactly can this mass egress be attributed?

Insufficient funds

The biggest reason is cost.

The cost of living in the Bay Area is one of the steepest on the planet. Startups in the Valley pay four times what they would in any other city in the country. In fact, just last year the California Association of Realtors reported that a typical family in San Francisco has to make over $300,000 a year in order to afford a median-priced house tagged at just over a million dollars. That includes a 20 percent down payment and an $8,000 monthly payment. Because most of the startups in Silicon Valley are in their infancies, the engineers, programmers, and non-technical employees don't get compensated enough to afford such a living. As a result, they are leaving the Bay Area in droves for places where the cost of living is manageable.

One location that tech startup entrepreneurs are flocking to is the university. Universities are also retaining tech wunderkinds on campus to blossom their startups, rather than seeing them leave for the microprocessor motherland known as Silicon Valley.

Now entering university life

One of the biggest reasons universities have become hotbeds for tech startups is that campuses provide a means for people with multidisciplinary backgrounds to intermingle within the same space. A chemical engineering student with a great idea might meet an MBA during a startup launch party. Together they can build and market the second iteration of "Secret Stuff" from Space Jam, or whatever that student has in mind.

The point is that universities position aspiring entrepreneurs to network with the right people for building their company from the ground up. Even the Innovation Leadership Forum attests that innovation is born when different ways of thinking clash. That is precisely what happens on campuses every day.

Furthermore, college students also have more room to take risks. Most aspiring entrepreneurs in college between 18 and 25 are not married, do not have kids, mortgages, or any other major financial responsibilities. This allows them to have the luxury of leeway when it comes to experimenting and trial and error.

The ecosystem of innovation

In essence, academic incubators are courting tech entrepreneurs because universities offer an ecosystem designed to support and grow startups from conception to commercialization. This ecosystem includes a space where researchers, faculty, and students of all disciplines interact and form working relationships. In many cases, it also includes university owned equipment and laboratories for use by startup researchers.

There is, of course, incentive for universities to concentrate so many resources to building incubators and luring startup entrepreneurs. There is an inherent sense of responsibility that universities have to create an academic climate that encourages students to explore new ideas. A sense of responsibility that encourages them to take more risks; to be fearless in their quest to use their intellect to enrich lives; to dream.

Moreover, university incubators also position schools as progressive institutions. Such positioning attracts elite researchers and enhances a university's reputation. Further, these incubators forge a bridge that links industry and academia in a way that Silicon Valley does not. That's because with academic incubators, startups are a stone's throw away from a place teeming with researchers, scientists, hungry students, and aspiring entrepreneurs: the university campus.

Consequently, it is no wonder that tech startups are leaving Silicon Valley for universities. It's also no surprise that students who have graduated are staying with their university's incubators to develop their companies. There, they have a place that cultivates innovation, encourages risk-taking, and is set up specifically to help them bring their tech to the world. In short, the university has become a hub set up to be conducive to thriving tech startups. And tech entrepreneurs have noticed.

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This article originally appeared on the University of Houston's The Big Idea.

Rene Cantu is the writer and editor at UH Division of Research.

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Greentown Labs names Lawson Gow as its new Houston leader

head of hou

Greentown Labs has named Lawson Gow as its Head of Houston.

Gow is the founder of The Cannon, a coworking space with seven locations in the Houston area, with additional partner spaces. He also recently served as managing partner at Houston-based investment and advisory firm Helium Capital. Gow is the son of David Gow, founder of Energy Capital's parent company, Gow Media.

According to Greentown, Gow will "enhance the founder experience, cultivate strategic partnerships, and accelerate climatetech solutions" in his new role.

“I couldn’t be more excited to join Greentown at this critical moment for the energy transition,” Gow said in a news release. “Greentown has a fantastic track record of supporting entrepreneurs in Houston, Boston, and beyond, and I am eager to keep advancing our mission in the energy transition capital of the world.”

Gow has also held analyst, strategy and advising roles since graduating from Rice University.

“We are thrilled to welcome Lawson to our leadership team,” Georgina Campbell Flatter, CEO of Greentown Labs, added in the release. “Lawson has spent his career building community and championing entrepreneurs, and we look forward to him deepening Greentown’s support of climate and energy startups as our Head of Houston.”

Gow is the latest addition to a series of new hires at Greentown Labs following a leadership shakeup.

Flatter was named as the organization's new CEO in February, replacing Kevin Dutt, Greentown’s interim CEO, who replaced Kevin Knobloch after he announced that he would step down in July 2024 after less than a year in the role.

Greentown also named Naheed Malik its new CFO in January.

Timmeko Moore Love was named the first Houston general manager and senior vice president of Greentown Labs. According to LinkedIn, she left the role in January.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.