A few local designers have pivoted to create face masks for local health care workers. Photo courtesy of Magpies & Peacocks

The coronavirus is sweeping the globe and creating new challenges. Notably, companies are not able to keep up with the demand for the N95 masks needed to keep the health care workers safe. Now, Houston's fashion industry is stepping up.

Megan Eddings, founder of Accel Lifestyle, says an article she read about the Centers for Disease Control and Prevention (CDC) advising health care professionals to wear homemade masks or bandanas due to the shortage of the N95 masks inspired her. She was compelled to help combat the COVID-19 pandemic locally and nationwide.

"Accel's Prema fabric was created to prevent the growth of bacteria," Eddings tells CultureMap. "The fabric can be washed up to 100 times and it will still be 99.99-percent anti-bacteria."

Eddings says it dawned on her that she has over 500 shirts made, here in Houston, that could easily be recreated into masks. Her supply chain team consists of 20 sewers and she notes that number can quickly double.

"We have enough supplies here to make 9,000 masks and I have 2,800 yards of fabric sitting at my factory in California," she says. "That's enough fabric to make more than 100,000 masks."

Eddings and her team also tell CultureMap that 47,000 yards of elastic is en route to the Bayou City this week.

"I knew this was serious when the president of MD Anderson responded to my Saturday morning email within three minutes of sending," she says. "He's interested, and they want the infection control team to analyze the fabric."

Other local hospitals interested in Accel Lifestyle's masks are Methodist, Texas Children's, Baylor, and Memorial Hermann. The Memorial Sloan Kettering Cancer Center in New York City has also shown interest as well as Yale's New Haven Hospital in New Haven, Connecticut.

Accel's masks are made out of their specialty anti-bacteria fabric. Photo courtesy of Accel

When Chloe Dao made the decision to temporarily close her Rice Village boutique last Tuesday, offering shopping requests by appointment only, she posted a video to her Instagram account the following day about the emotional roller coaster she's been on surrounding the COVID-19 outbreak.

In the video, Dao says she wanted to play a role in helping her community by creating a pattern and hand sewing 100 washable face masks with pockets. She noted in the caption that the pocket allows for extra filtration but that because it's a fabric mask, it does not stop the spread of the virus. Dao also recommends washing the mask before wearing it.

With production underway since her initial 100 masks, available in small/medium and medium/large, Dao and her team have produced close to 1,000 masks for Houstonians who reached out via social media.

"The requests are overwhelming," a representative for the label tells CultureMap. "We're now shifting our focus to help those on the front line of the coronavirus outbreak; the doctors, nurses, family members of doctors and nurses."

For those who would like to donate to Dao's efforts to continue producing these washable masks, click here.

Houston-based, internationally recognized nonprofit design house, Magpies & Peacocks, and Inclán Studio, a local women's ready-to-wear fashion label, are upcycling together to create nonwoven polypropylene masks, which will be distributed to Houston-area hospitals.

Founder and CEO, Sarah-Jayne Smith and vice president and director of communications/PR, Ahshia Berry, tells CultureMap that partnering together was never a question for either of our brands but more "how can we pull our resources together and help during these trying times."

Clarence Lee, a designer at Inclán Studio, tells CultureMap he searched the studio to find elastic cording that didn't get used in past collections.

"Waste as a resource and upcycling material for good use has never been more important than it is right now," Magpies & Peacocks writes on an Instagram post.

Houston Arts Alliance and Visit Houston donated excess promotional products and now, are deconstructed to reuse the material for these masks.

"It's actually a spun plastic, not a fabric, so it works effectively as a filter, and is more moisture resistant," Magpies & Peacocks tells CultureMap. "It's more compliant and efficient for the current exposure to the service industry in the midst of the crisis."

Lee, who is also a lead designer for Magpies & Peacocks, and serves as an executive board member for the nation's exclusive nonprofit design house, tells CultureMap that for them, it simply boils down to help in any capacity, especially after seeing what's happening across the country with the shortage of supplies.

He notes that they may not have all the supplies, but they do have the capability and time to sew to help those that are on the frontline, fighting and sacrificing everything they have.

"[Houston] is our home, and we all have a part to play in helping fight this," he says. "The [fashion] industry has a major role, and now is definitely the time to show how valuable it can be."

Magpies & Peacocks and Inclán Studio aim to produce 500-600 masks, and hopefully more, should they come across more materials, Lee tells CultureMap. Seven volunteers are helping to sew these nonwoven polypropylene masks.

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This article originally ran on CultureMap.

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.