Innovation isn't always the safest field. Here's what to consider within incident reporting. Graphic byMiguel Tovar/University of Houston

Exploding refrigerator? Chemical splash on the face? These are not just personally devastating lab incidents, they are also expensive.

For instance, awhile back, the University of Hawaii faced a total $115,500 fine for 15 workplace safety violations after a laboratory explosion where a postdoctoral researcher lost one of her arms. Beryl Lieff Benderly wrote in Science that the accident “resulted from a static electricity charge that ignited a tank containing a highly flammable, pressurized mixture of hydrogen, oxygen and carbon dioxide.”

Referred to as “incidents,” they are defined by University of California Santa Barbara (UCSB) in this way: “An incident is an event that results in or causes injury or damage to someone or something, or an event that has the potential to result in or cause injury or damage.”

But when asked which incidents are reportable, the answer is uniform across all research universities: all incidents must be reported.

Incidentally...

There are websites dedicated to laboratory accidents, like this one at UCSB. It lists the two accidents mentioned in this blog’s first sentence. University of Michigan Environment, Health and Safety’s website said, “Being safe at the University of Michigan requires a positive safety culture where we learn from mistakes and near-misses in order to improve and prevent future occurrences. It is vital that you report all ‘incidents’ including near- misses, injuries resulting from your activities, non-compliance with safety and environmental rules, and general unsafe work conditions so that we can learn and grow.” Northwestern University’s website on Research Health and Safety said, “Always report ‘near-misses’ just as you would an incident that causes injury or harm to property.”

Near-missing

You may be asking, what constitutes a “near-miss”? At Western Kentucky University, for example: “A laboratory “near-miss” is an unplanned situation, where with minor changes to time or setting, could have easily resulted in damage or injury to person or property. A near-miss is characterized as having little, if any, immediate impact on individuals, processes, or the environment, but provides insight into accidents that could happen.” Laboratory near misses may cause chemical spills, explosions and bodily injury, but can be treated with first-aid.

Form finding

Most universities have a form to fill out if there is an incident that could have led to a severe injury or death. The form asks for a description of the incident and even asks, in some instances, “Why did it happen?” These should be made out comprehensively and quickly.

OSHA

The Occupational Safety and Health Administration (OSHA) has a reporting process, aside from what each university requires. They need information when you call. The OSHA website states: “Be prepared to supply: Business name; names of employees affected; location and time of the incident, brief description of the incident; contact person and phone number.”

There are even time limits for how quickly one must report a severe injury that requires an in-patient hospitalization, amputation or loss of an eye (24) or fatality.

(It’s eight hours.)

The fact that “losing an eye” is one of just four reasons to contact OSHA, you may wonder, “Are a lot of people blinded in the lab, often?” Also, “Where can I buy safety goggles?”

“Are a lot of people blinded in the lab, often? Also, where can I buy safety goggles?”

The big idea

There are many websites which detail lab disasters. Some are cautionary tales, some are avoidable situations. Just be sure to wear your Personal Protective Equipment (PPE) and be safe out there. Or rather, in there.

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This article originally appeared on the University of Houston's The Big Idea. Sarah Hill, the author of this piece, is the communications manager for the UH Division of Research.

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Houston ecommerce scale-up company acquires Amazon advertising partner

all aboard

A Houston tech company has tapped an Amazon partner in a strategic acquisition and is bringing the company's full team on board.

Cart.com acquired Ohio-based Amify, a company that provides optimization and advertising solutions. The terms of the deal were not disclosed but Cart.com will on board Amify’s entire employee base, including its founder Ethan McAfee, CEO Chris Mehrabi, and COO Christine McCambridge.

As chief delivery officer, Mehrabi will take the helm of Cart.com’s professional services business and McCambridge will lead Cart.com’s marketplace services team as vice president of marketplace services operations.

“I’m happy to welcome the entire Amify team to Cart.com and have industry veterans Chris Mehrabi and Christine McCambridge join our leadership team,” Cart.com Founder and CEO Omair Tariq says in a news release. “Amify has been widely recognized for their expertise and technology and we’re excited to leverage their experience to help our customers maximize their potential across channels.”

Cart.com's membership will have access to Amify's proprietary technology platform, including advertising, creative content, supply chain strategy, and analytics. The company, which was founded in 2011, currently supports over 50 global brands and manages approximately $1 billion in gross merchandise value. According to LinkedIn, Amify has over 50 employees.

“We could not be more excited to join Cart.com and leverage the company’s resources and scale to deliver value to both our customers and employees,” Mehrabi says. “I’m honored to step into the role of Chief Delivery Officer and contribute to Cart.com’s incredible growth story and innovative reputation.”

Founded in Houston in 2020, Cart.com provides comprehensive physical and digital infrastructure for online merchants. The company raised a $60 million series C and grown its customer base to over 6,000 users. After making several acquisitions, the company also operates 14 fulfillment centers nationwide.

Earlier this year, Tariq sat down with the Houston Innovators Podcast to share a bit about how the company is currently in scale-up mode.

Houston health tech innovator collaborates on promising medical device funded by DOD

team work

The United States Department of Defense has awarded a grant that will allow the Texas Heart Institute and Rice University to continue to break ground on a novel left ventricular assist device (LVAD) that could be an alternative to current devices that prevent heart transplantation and are a long-term option in end-stage heart failure.

The grant is part of the DOD’s Congressionally Directed Medical Research Programs (CDMRP). It was awarded to Georgia Institute of Technology, one of four collaborators on the project that will be designed and evaluated by the co-investigator Yaxin Wang. Wang is part of O.H. “Bud” Frazier’s team at Texas Heart Institute, where she is director of Innovative Device & Engineering Applications Lab. The other institution working on the new LVAD is North Carolina State University.

The project is funded by a four-year, $7.8 million grant. THI will use about $2.94 million of that to fund its part of the research. As Wang explained to us last year, an LVAD is a minimally invasive device that mechanically pumps a person’s own heart. Frazier claims to have performed more than 900 LVAD implantations, but the devices are far from perfect.

The team working on this new research seeks to minimize near-eventualities like blood clot formation, blood damage, and driveline complications such as infection and limitations in mobility. The four institutions will try to innovate with a device featuring new engineering designs, antithrombotic slippery hydrophilic coatings (SLIC), wireless power transfer systems, and magnetically levitated driving systems.

Wang and her team believe that the non-contact-bearing technology will help to decrease the risk of blood clotting and damage when implanting an LVAD. The IDEA Lab will test the efficacy and safety of the SLIC LVAD developed by the multi-institutional team with a lab-bench-based blood flow loop, but also in preclinical models.

“The Texas Heart Institute continues to be a leading center for innovation in mechanical circulatory support systems,” said Joseph G. Rogers, MD, the president and CEO of THI, in a press release.

“This award will further the development and testing of the SLIC LVAD, a device intended to provide an option for a vulnerable patient population and another tool in the armamentarium of the heart failure teams worldwide.”

If it works as hypothesized, the SLIC LVAD will improve upon current LVAD technology, which will boost quality of life for countless heart patients. But the innovation won’t stop there. Technologies that IDEA Lab is testing include wireless power transfer for medical devices and coatings to reduce blood clotting could find applications in many other technologies that could help patients live longer, healthier lives.

Houston investor on SaaS investing and cracking product-market fit

Houston innovators podcast episode 230

Aziz Gilani's career in tech dates back to when he'd ride his bike from Clear Lake High School to a local tech organization that was digitizing manuals from mission control. After years working on every side of the equation of software technology, he's in the driver's seat at a local venture capital firm deploying funding into innovative software businesses.

As managing director at Mercury, the firm he's been at since 2008, Gilani looks for promising startups within the software-as-a-service space — everything from cloud computing and data science and beyond.

"Once a year at Mercury, we sit down with our partners and talk about the next investment cycle and the focuses we have for what makes companies stand out," Gilani says on the Houston Innovators Podcast. "The current software investment cycle is very focused on companies that have truly achieved product-market fit and are showing large customer adoption."



An example of this type of company is Houston-based RepeatMD, which raised a $50 million series A round last November. Mercury's Fund V, which closed at an oversubscribed $160 million, contributed to RepeatMD's round.

"While looking at that investment, it really made me re-calibrate a lot of my thoughts in terms what product-market fit meant," Gilani says. "At RepeatMD, we had customers that were so eager for the service that they were literally buying into products while we were still making them."

Gilani says he's focused on finding more of these high-growth companies to add to Mercury's portfolio amidst what, admittedly, has been a tough time for venture capital. But 2024 has been looking better for those fundraising.

"We've some potential for improvement," Gilani says. "But overall, the environment is constrained, interest rates haven't budged, and we've seen some potential for IPO activity."

Gilani shares more insight into his investment thesis, what areas of tech he's been focused on recently, and how Houston has developed as an ecosystem on the podcast.