5 most popular innovation stories in Houston this week

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From a hyperloop update to new hires across town, here's what you're reading this week. Pexels

Editor's note: This week's trending stories were pretty people centric with the innovators to know from Monday and two new hires at major innovation institutions. Plus, we got an update about the potential hyperloop system and The Cannon scored a fund partnership.

3 Houston innovators to know this week

These three innovators to know are responsible for solving problems here in Houston. Courtesy photos

A good innovator sees a need and fills it. Whether it's a bigger budget for new hospital technology, a network for female software developers in Houston, or access to creatives for nonprofits, these three Houston innovators are responsible for filling the needs of Houston's innovation ecosystem. Click here to read the full story.

TMC names former JLABS leader as the director of the Innovation Institute

Tom Luby will run the Texas Medical Center's Innovation Institute. Courtesy of TMC

The Texas Medical Center didn't have to go very far to find its new Innovation Institute director. Tom Luby, who most recently served as the site head for Johnson & Johnson Innovation's JLABS @ TMC, has been hired for the position. Luby replaces Erik Halvorsen, who left abruptly in December. Click here to read the full story.

Station Houston hires new director to grow partnerships and community engagement

Deanea LeFlore is Station Houston's new director of community engagement, partnerships, and education. Courtesy of Station Houston

A downtown Houston startup acceleration hub has created a new position focused on expanding the nonprofit's partnerships, engagement, and opportunities. Station Houston hired Deanea LeFlore as director of community engagement, partnerships, and education. Previously, LeFlore served as chief of protocol for the city of Houston and a vice president of the Greater Houston Convention and Visitors Bureau. Click here to read the full story.

Rice University's angel network to be powered by Cannon Ventures

The Rice Angel Network will now be powered by Cannon Ventures. Photo courtesy of Rice University

In an effort to better connect Houston entrepreneurs with angel funds, the Rice Angel Network and Cannon Ventures have formed a new partnership. RAN will now be powered by Cannon Ventures, the investment arm of The Cannon, a West Houston coworking space. Click here to read the full story.

30-minute hyperloop from Houston to Dallas on fast track with push from federal government

U.S. Transportation Secretary Elaine Chao used SXSW to make the announcement. Photo courtesy of Hyperloop One

Creation of a transportation-in-a-tube system that promises to whisk passengers from Houston to Dallas in 30 minutes got a big boost March 12 from the federal government. During an appearance at SXSW, U.S. Transportation Secretary Elaine Chao said she has established a transportation technology council that will aim to clear regulatory and legal roadblocks for the traffic-busting Virgin Hyperloop One concept and similar transit innovations. Click here to read the full story.


U.S. Transportation Secretary Elaine Chao used SXSW to make the announcement. Photo courtesy of Hyperloop One

30-minute hyperloop from Houston to Dallas on fast track with push from federal government

Looped in

Creation of a transportation-in-a-tube system that promises to whisk passengers from Houston to Dallas in 30 minutes got a big boost March 12 from the federal government.

During an appearance at SXSW, U.S. Transportation Secretary Elaine Chao said she has established a transportation technology council that will aim to clear regulatory and legal roadblocks for the traffic-busting Virgin Hyperloop One concept and similar transit innovations.

In September 2017, the company behind Hyperloop One picked a 640-mile route in Texas for the initiative. The futuristic system — with passengers riding in pods carried through a massive tube — would connect Houston, Austin, Dallas-Fort Worth, Laredo, and San Antonio. Hyperloop One would provide two stops each in the Dallas-Fort Worth and Houston areas, and one each in Austin, Laredo, and San Antonio.

The north-south leg of Hyperloop One would run between Dallas-Fort Worth and Laredo, while the east-west leg would operate between Houston and San Antonio. As imagined now, a trip between Austin and Dallas would last 19 minutes at speeds up to 670 mph — two to three times faster than high-speed rail and 10 to 15 times faster than traditional rail. A ride from Houston to Austin would take 21 minutes, while a trek from Houston to San Antonio would last 26 minutes.

"Texas is exploring how to make hyperloop a reality at the state and local level, but federal support is a huge key for us to be certified and successful," Ryan Kelly, head of marketing and communications for Virgin Hyperloop One, tells CultureMap. "It is exciting that the federal government is recognizing us as a potential new mode of transportation that can be a leap forward for America. Hopefully, Texas can be a first mover."

Aside from Texas, Virgin Hyperloop One has U.S. projects underway in Colorado, Missouri, and the Chicago-Columbus-Pittsburgh corridor. Virgin Group, led by Sir Richard Branson, is among the investors in Hyperloop One.

The federal council unveiled at SXSW will help fast-track a first-of-its-kind transportation network in the U.S. that shares components with trains, planes, and self-driving vehicles. Members of the council will explore technological innovations, such as transit tunnels and self-driving vehicles, in the quest to speed up development of Virgin Hyperloop One and other emerging modes of mass transportation.

"Hyperloop is a new mode of transportation that is built for the 21st century," Jay Walder, CEO of Virgin Hyperloop One, says in a release. "We want to be the company that spearheads the next giant leap forward in transportation here in the United States, but we know we can't do it alone."

Kelly says it's unclear when Texas passengers might be able to travel on Virgin Hyperloop One's network, but the company hopes the first route — wherever it may be — will be ready by the end of 2028.

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This story originally ran on CultureMap.

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6 female-founded startups shaping the Houston innovation ecosystem

meet the finalists

Female-founded businesses reached a new milestone last year. According to payroll company Gusto, female founders launched 49 percent of new businesses in 2024, reaching near parity with male-founded businesses for the first time.

And though they still face challenges, with access to VC funding at the top of the list, those women-led companies are driving major impact in the startup and innovation ecosystem.

The fifth-annual Houston Innovation Awards will honor six women-led startups that are shaping Houston innovation in our Female-founded Businesses category.

The finalists for the 2025 award, selected by our esteemed panel of judges, range from a company developing natural carbon-free fuel to another launching at-home sleep apnea technology.

Read more about these innovative startups and the visionary female founders behind them below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled at our live awards ceremony.

Tickets are now on sale for this exclusive event celebrating all things Houston innovation.

Anning Corporation

Clean energy company Anning Corporation is working to develop geologic hydrogen, a natural carbon-free fuel, using its proprietary stimulation approaches and advanced exploration modeling. The company said that geologic hydrogen has the potential to be the lowest-cost source of reliable baseload electricity in the U.S.

The company was founded by CEO Sophie Broun in 2024 and is a member of Greentown Labs. Last month, it also announced that it was chosen to participate in Breakthrough Energy’s prestigious Fellows Program. Anning raised a pre-seed round this year and is currently raising a $6 million seed round.

Bairitone Health

Bairitone Health is bringing anatomy imaging for sleep apnea to the home environment. The company's platform maps users' anatomy during natural sleep using a facial patch to determine the root cause of airway obstruction. It then offers effective therapies for each patient. The system is currently in the research and development phase and is being used in clinical trials and studies.

The company was founded in 2022 in the Texas Medical Center's Biodesign program by CEO Meagan Pitcher, CTO Onur Kilic and chief medical officer Britt Cross. It was a member of Activate Houston's inaugural cohort and has participated in numerous accelerators and incubators. It raised a pre-seed round last year of $435,000.

Brain Haven

Founded at the University of Houston, Brain Haven is developing neuroscience-based, clinically validated protocols that use sensory stimulation through smell and sound to offer a natural and non-invasive way to activate the brain and preserve neuroplasticity. The company aims to deliver an accessible and affordable way for the aging population to preserve memory, delay cognitive decline and improve quality of life.

The company was co-founded by Gail Aflalo, a graduate student in the University of Houston College of Optometry, and Jokūbas Žiburkus, an associate professor in the department of biology and biochemistry at UH. It was selected to participate in the 2024 Innov8 Cohort, where it won the cohort's Startup Pitch Day, and was included in Class 13 of UH RED Labs. Brain Haven was awarded $70,000 in seed funding from UH in June 2025 to support a year-long research initiative in adults aged 50 and above.

FlowCare

Sugar Land-based FlowCare is developing a period health platform that integrates smart dispensers, education and healthcare into one system to make free, high-quality organic period products more accessible.

The company was founded by CEO Tanu Jain, a registered nurse and product management executive, in 2024. It participated in the TiE Women Program and the Houston Community College Business Plan Competition, placing in the top five in both pitch competitions.

March Biosciences

Houston cell therapy company March Biosciences aims to treat unaddressed challenging cancers, with its MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma, currently in Phase 2 clinical trials.

The company was founded in 2021 by CEO Sarah Hein, Max Mamonkin and Malcolm Brenner and was born out of the TMC Accelerator for Cancer Therapeutics. The company completed a $29.6 million series A last year and also raised a $4.2 million seed round.

TrialClinIQ

Houston-based TrialClinIQ is an AI-powered clinical trial recruitment platform that helps identify, qualify and enroll eligible patients in appropriate trials faster and more accurately.

The company was founded in 2025 by CEO Jontel Pierce and Janette Obi.

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The Houston Innovation Awards program is sponsored by Houston Community College, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.

Former NASA astronaut, official joins Venus Aerospace board

astronaut appointment

Retired Air Force colonel and former NASA astronaut Pamela Melroy, who previously served as deputy administrator of NASA, recently joined the board of directors at Houston-based Venus Aerospace.

Venus Aerospace, a startup founded in 2020, develops rocket engine technology, including rotating rocket detonation engines for hypersonic flights. These engines promise higher power, greater fuel efficiency and lower emissions than conventional rocket engines or jet engines, according to the Interesting Engineering website. The global rocket propulsion market is expected to grow from $9.5 billion in 2025 to $29.9 billion by 2034, according to a forecast by ResearchAndMarkets.com.

“Advanced rocket propulsion has been of interest to me for over a decade, and Venus Aerospace’s recent achievements in demonstrating the stability of rotating detonation rocket engines represent a significant development,” says Melroy, who left NASA earlier this year and is now a self-employed consultant living in Arlington, Virginia.

Melroy, a member of the United States Astronaut Hall of Fame, has built an illustrious career in the aerospace sector. Aside from being a NASA official, she was:

  • One of only two female astronauts to command a space shuttle mission
  • Deputy program manager of Orion space exploration initiatives at aerospace and defense contractor Lockheed Martin
  • Senior technical adviser and director of field operations for the Federal Aviation Administration’s Office of Commercial Space Transportation, where she came up with the first safety guidelines for commercial human spaceflight
  • Deputy director of the Tactical Technology Office at the Defense Advanced Research Projects Agency (DARPA).
  • An adviser for the establishment of the Australian Space Agency

Venus Aerospace said in a news release that as a leader at three federal agencies, “Melroy shaped America’s strategy in space, accelerated commercial space partnerships, and deepened space exploration.”

Sassie Duggleby, co-founder and CEO of Venus Aerospace, called Melroy “a preeminent leader in the world of aerospace.”

In May, Venus Aerospace completed the inaugural test flight of its rotating detonation rocket engine. The startup, whose headquarters is at the Houston Spaceport, says it’s the only company in the world that has manufactured a flight-proven, high-thrust rotating detonation rocket engine.

On the horizon for Venus Aerospace is production of Stargazer M4, a high-speed aircraft capable of two-hour global travel.

Venus Aerospace’s investors include Airbus Ventures, America’s Frontier Fund, Trousdale Ventures, and Prime Movers Lab. The startup also gets support from the Air Force Research Laboratory (AFWERX), the Air Force, NASA and DARPA.

Jordan Blashek, co-founder and managing partner of America’s Frontier Fund, which backs startups creating breakthrough technologies, said his firm’s investment in Venus Aerospace “underscores our focus on supporting American companies that are revolutionizing industries of the future.”

“With recent hypersonic advancements from China and Russia, safeguarding American innovation and securing our industrial base has never been more urgent,” Blashek added. “Venus Aerospace is poised to redefine hypersonic flight and ensure America’s continued leadership in aerospace innovation.”

Since its founding, Venus Aerospace has raised $78.3 million in investments, according to PitchBook data.

Texas-based energy startup raises $1 billion on heels of Houston expansion

Powering Up

Austin-based startup Base Power, which offers battery-supported energy in the Houston area and other regions, has raised $1 billion in series C funding—making it one of the largest venture capital deals this year in the U.S.

VC firm Addition led the $1 billion round. All of Base Power’s existing major investors also participated, including Trust Ventures, Valor Equity Partners, Thrive Capital, Lightspeed Venture Partners, Andreessen Horowitz (a16z), Altimeter, StepStone Group, 137 Ventures, Terrain, Waybury Capital, and entrepreneur Elad Gil. New investors include Ribbit Capital, Google-backed CapitalG, Spark Capital, Bond, Lowercarbon Capital, Avenir Growth Capital, Glade Brook Capital Partners, Positive Sum and 1789 Capital Management.

Coupled with the new $1 billion round, Base Power has hauled in more than $1.27 billion in funding since it was founded in 2023.

Base Power supplies power to homeowners and the electric grid through a distributed storage network.

“The chance to reinvent our power system comes once in a generation,” Zach Dell, co-founder and CEO of Base Power, said in a news release. “The challenge ahead requires the best engineers and operators to solve it, and we’re scaling the team to make our abundant energy future a reality.”

Zach Dell is the son of Austin billionaire and Houston native Michael Dell, chairman and CEO of Round Rock-based Dell Technologies.

In less than two years, Base Power has developed more than 100 megawatt-hours of battery-enabled storage capacity. One megawatt-hour represents one hour of energy use at a rate of one million watts.

Base Power recently expanded its service to the city of Houston. It already was delivering energy to several other communities in the Houston area. To serve the Houston region, the startup has opened an office in Katy.

The startup also serves the Dallas-Fort Worth and Austin markets. At some point, Base Power plans to launch a nationwide expansion.

To meet current and future demand, Base Power is building its first energy storage and power electronics factory at the former downtown Austin site of the Austin American-Statesman’s printing presses.

“We’re building domestic manufacturing capacity for fixing the grid,” Justin Lopas, co-founder and chief operating officer of Base Power, added in the release. “The only way to add capacity to the grid is [by] physically deploying hardware, and we need to make that here in the U.S. ... This factory in Austin is our first, and we’re already planning for our second.”

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This article originally appeared on EnergyCapitalHTX.com.

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