5 most popular innovation stories in Houston this week

Now trending

From a hyperloop update to new hires across town, here's what you're reading this week. Pexels

Editor's note: This week's trending stories were pretty people centric with the innovators to know from Monday and two new hires at major innovation institutions. Plus, we got an update about the potential hyperloop system and The Cannon scored a fund partnership.

3 Houston innovators to know this week

These three innovators to know are responsible for solving problems here in Houston. Courtesy photos

A good innovator sees a need and fills it. Whether it's a bigger budget for new hospital technology, a network for female software developers in Houston, or access to creatives for nonprofits, these three Houston innovators are responsible for filling the needs of Houston's innovation ecosystem. Click here to read the full story.

TMC names former JLABS leader as the director of the Innovation Institute

Tom Luby will run the Texas Medical Center's Innovation Institute. Courtesy of TMC

The Texas Medical Center didn't have to go very far to find its new Innovation Institute director. Tom Luby, who most recently served as the site head for Johnson & Johnson Innovation's JLABS @ TMC, has been hired for the position. Luby replaces Erik Halvorsen, who left abruptly in December. Click here to read the full story.

Station Houston hires new director to grow partnerships and community engagement

Deanea LeFlore is Station Houston's new director of community engagement, partnerships, and education. Courtesy of Station Houston

A downtown Houston startup acceleration hub has created a new position focused on expanding the nonprofit's partnerships, engagement, and opportunities. Station Houston hired Deanea LeFlore as director of community engagement, partnerships, and education. Previously, LeFlore served as chief of protocol for the city of Houston and a vice president of the Greater Houston Convention and Visitors Bureau. Click here to read the full story.

Rice University's angel network to be powered by Cannon Ventures

The Rice Angel Network will now be powered by Cannon Ventures. Photo courtesy of Rice University

In an effort to better connect Houston entrepreneurs with angel funds, the Rice Angel Network and Cannon Ventures have formed a new partnership. RAN will now be powered by Cannon Ventures, the investment arm of The Cannon, a West Houston coworking space. Click here to read the full story.

30-minute hyperloop from Houston to Dallas on fast track with push from federal government

U.S. Transportation Secretary Elaine Chao used SXSW to make the announcement. Photo courtesy of Hyperloop One

Creation of a transportation-in-a-tube system that promises to whisk passengers from Houston to Dallas in 30 minutes got a big boost March 12 from the federal government. During an appearance at SXSW, U.S. Transportation Secretary Elaine Chao said she has established a transportation technology council that will aim to clear regulatory and legal roadblocks for the traffic-busting Virgin Hyperloop One concept and similar transit innovations. Click here to read the full story.


U.S. Transportation Secretary Elaine Chao used SXSW to make the announcement. Photo courtesy of Hyperloop One

30-minute hyperloop from Houston to Dallas on fast track with push from federal government

Looped in

Creation of a transportation-in-a-tube system that promises to whisk passengers from Houston to Dallas in 30 minutes got a big boost March 12 from the federal government.

During an appearance at SXSW, U.S. Transportation Secretary Elaine Chao said she has established a transportation technology council that will aim to clear regulatory and legal roadblocks for the traffic-busting Virgin Hyperloop One concept and similar transit innovations.

In September 2017, the company behind Hyperloop One picked a 640-mile route in Texas for the initiative. The futuristic system — with passengers riding in pods carried through a massive tube — would connect Houston, Austin, Dallas-Fort Worth, Laredo, and San Antonio. Hyperloop One would provide two stops each in the Dallas-Fort Worth and Houston areas, and one each in Austin, Laredo, and San Antonio.

The north-south leg of Hyperloop One would run between Dallas-Fort Worth and Laredo, while the east-west leg would operate between Houston and San Antonio. As imagined now, a trip between Austin and Dallas would last 19 minutes at speeds up to 670 mph — two to three times faster than high-speed rail and 10 to 15 times faster than traditional rail. A ride from Houston to Austin would take 21 minutes, while a trek from Houston to San Antonio would last 26 minutes.

"Texas is exploring how to make hyperloop a reality at the state and local level, but federal support is a huge key for us to be certified and successful," Ryan Kelly, head of marketing and communications for Virgin Hyperloop One, tells CultureMap. "It is exciting that the federal government is recognizing us as a potential new mode of transportation that can be a leap forward for America. Hopefully, Texas can be a first mover."

Aside from Texas, Virgin Hyperloop One has U.S. projects underway in Colorado, Missouri, and the Chicago-Columbus-Pittsburgh corridor. Virgin Group, led by Sir Richard Branson, is among the investors in Hyperloop One.

The federal council unveiled at SXSW will help fast-track a first-of-its-kind transportation network in the U.S. that shares components with trains, planes, and self-driving vehicles. Members of the council will explore technological innovations, such as transit tunnels and self-driving vehicles, in the quest to speed up development of Virgin Hyperloop One and other emerging modes of mass transportation.

"Hyperloop is a new mode of transportation that is built for the 21st century," Jay Walder, CEO of Virgin Hyperloop One, says in a release. "We want to be the company that spearheads the next giant leap forward in transportation here in the United States, but we know we can't do it alone."

Kelly says it's unclear when Texas passengers might be able to travel on Virgin Hyperloop One's network, but the company hopes the first route — wherever it may be — will be ready by the end of 2028.

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This story originally ran on CultureMap.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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