Fram2, operated by SpaceX, is targeting to launch Monday, March 31. The crew will conduct six TRISH experiments on board. Photo courtesy TRISH.

Houston's Translational Research Institute for Space Health, or TRISH, will send its latest experiments into space aboard the Fram2 mission, the first all-civilian human spaceflight mission to launch over the Earth’s polar regions.

Fram2, operated by SpaceX, is targeting to launch Monday, March 31, at NASA’s Kennedy Space Center in Florida. The crew of four is expected to spend several days in polar orbit aboard the SpaceX Dragon spacecraft in low Earth orbit. TRISH’s research projects are among 22 experiments that the crew will conduct onboard.

The crew's findings will add to TRISH's Enhancing eXploration Platforms and ANalog Definition, or EXPAND, program and will be used to help enhance human health and performance during spaceflight missions, including missions to the moon and Mars, according to a release from TRISH.

“The valuable space health data that will be captured during Fram2 will advance our understanding of how humans respond and adapt to the stressors of space,” Jimmy Wu, TRISH deputy director and chief engineer and assistant professor in Baylor’s Center for Space Medicine, said in the release. “Thanks to the continued interest in furthering space health by commercial space crews, each human health research project sent into orbit brings us closer to improving crew member well-being aboard future spaceflight missions.”

The six TRISH projects on Fram2 include:

  • Cognitive and Physiologic Responses in Commercial Space Crew on Short-Duration Missions, led by Dr. Mathias Basner at the University of Pennsylvania Perelman School of Medicine. The crew will wear a Garmin smartwatch and a BioIntelliSense BioButton® medical grade device to track cognitive performance, including memory, spatial orientation, and attention before, during, and after the mission.
  • Otolith and Posture Evaluation II, led by Mark Shelhamer at Johns Hopkins University. The experiment will look at how astronauts’ eyes sense and respond to motion before and after spaceflight to better understand motion sickness in space.
  • REM and CAD Radiation Monitoring for Private Astronaut Spaceflight, led by Stuart George at NASA Johnson Space Center. This experiment will test space radiation exposure over the Earth’s north and south poles and how this impacts crew members.
  • Space Omics + BioBank, led by Richard Gibbs and Harsha Doddapaneni at Baylor College of Medicine. The experiment will use Baylor’s Human Genome Sequencing Center's Genomic Evaluation of Space Travel and Research program to gain insights from pre-flight and post-flight samples from astronauts.
  • Standardized research questionnaires, led by TRISH. The test asks a set of standardized research questionnaires for the crew to collect data on their sleep, personality, health history, team dynamics and immune-related symptoms.
  • Sensorimotor adaptation, led by TRISH. The project collects data before and after flight to understand sensorimotor abilities, change and recovery time to inform future missions to the moon.

TRISH, which is part of BCM’s Center for Space Medicine with partners Caltech and MIT, has launched experiments on numerous space missions to date, including Blue Origin's New Shepard rocket last November and Axiom Space's Ax-3 mission to the International Space Station last January.

Texas A&M University signed an agreement with NASA's Johnson Space Center last month, and the American Center for Manufacturing and Innovation signed a similar agreement a few weeks later. Photo via nasa.gov

NASA signs 2 public-private lease agreements at Houston campus to promote human space research

ready to launch

NASA and the American Center for Manufacturing and Innovation signed an agreement Thursday, Feb. 29 to lease underutilized land in a 240-acre Exploration Park at the agency's Johnson Space Center in Houston. The deal comes after a similar lease with the Texas A&M University System.

ACMI will enable the development of facilities to enable commercial and defense space manufacturing, while A&M reports that it will develop a facility for human spaceflight research and development.

These two public/private lease agreements allow industry and academia to use NASA Johnson land to create facilities for a collaborative development environment that increases commercial access and enhances the United States' commercial competitiveness in the space and aerospace industries.

“For more than 60 years, NASA Johnson has been the hub of human spaceflight,” NASA Johnson Director Vanessa Wyche says in a news release. “Exploration Park will be the next spoke in the larger wheel of a robust and durable space economy that will benefit not only exploration of the Moon, Mars and the asteroids, but all of humanity as the benefits of space exploration research roll home to Earth.”

Calling it the Space Systems Campus, ACMI plans to incorporate an applied research facility partnered with multiple stakeholders across academia, state and local government, the Department of Defense and regional economic development organizations.

"This Space Systems Campus will be a significant component within our objectives for a robust and durable space economy that will benefit not only the nation's efforts to explore the Moon, Mars and the asteroids, but all of humanity as the benefits of space exploration research roll home to Earth," Wyche says of the ACMI deal.

As the home of Mission Control Center for the agency's human space missions, astronaut training, robotics, human health and space medicine, NASA Johnson leads the way for the human exploration. Leveraging this unique role and location, Exploration Park will play a key role in helping the human spaceflight community attain U.S. goals for the commercialization and development of a robust space economy by creating an infrastructure that fosters a multi-use environment where academic researchers, aerospace companies and entrepreneurs can collaborate with NASA. Exploration Park will create an infrastructure that allows for a multi-use space hardware development environment, where academic researchers, aerospace companies and entrepreneurs can collaborate on space exploration's greatest challenges.

"ACMI Properties will develop this Campus to serve the needs of our future tenants, aerospace industry, the Department of Defense and other significant stakeholders that comprise our ecosystem approach," said Simon Shewmaker, head of development for ACMI Properties. "Our aim is to support human spaceflight missions for the next 40 years and beyond."

NASA issued an announcement for proposals for use of the undeveloped and underutilized land near Saturn Lane on June 9, 2023, and has just completed negotiations with ACMI to formalize the lease agreement. The parcel is outside of Johnson's controlled access area and adjacent to its main campus. NASA will lease the land for 20 years with two 20-year extension options, for a potential of up to 60 years.

In the coming years, NASA and its academic, commercial, and international partners will see the completion of the International Space Station Program, the commercial development of low Earth orbit, and the first human Artemis campaign missions establishing sustainable human presence on the Moon in preparation for human missions to Mars.

Johnson already is leading the commercialization of space with the commercial cargo and crew programs and private astronaut missions to the space station. The center also is supporting the development of commercial space stations in low Earth orbit, and lunar-capable commercial spacesuits and lunar landers that will be provided as services to both NASA and the private sector to accelerate human access to space. Through the development of Exploration Park, the center will broaden the scope of the human spaceflight community that is tackling the many difficult challenges ahead.

Emily Nelson is the new chief flight director for NASA. Photo via NASA.org

NASA names new chief flight director to work out of Houston's Johnson Space Center

ground control

The Mission Control Center at NASA’s Johnson Space Center in Houston has a new chief flight director.

In her new role, Emily Nelson leads the group that directs human spaceflight missions. She succeeds Amarillo native Holly Ridings, who held the job from 2018 to 2022. Ridings now is a leader of NASA’s Gateway Program, which is working to establish the first space station that orbits the moon.

“Emily’s tenure leading our flight control teams has proven that she is remarkably knowledgeable on the realities of human spaceflight and eminently composed when facing daunting challenges,” Norm Knight, NASA’s director of flight operations, says in a news release. “She is unequivocally the right person to lead our flight director office as we endeavor to push the boundaries of human spaceflight exploration.”

Nelson manages 31 flight directors and directors-in-training who oversee a human spaceflight missions involving the International Space Station and Artemis missions to the moon.

Nelson, born in Okinawa, Japan, and raised in Austin, earned a bachelor’s degree in mechanical engineering from the University of Texas at Austin in 1998. She joined NASA in 1998 as a flight controller in the space station’s thermal operations group.

She became a flight director in 2007. Since then, she has served as lead flight director for several missions, including the station’s fourth utilization and logistics flight with the space shuttle Atlantis in 2010 and a series of spacewalks to repair the Alpha Magnetic Spectrometer. She had been NASA’s deputy chief flight director before being named acting chief flight director following Ridings’ departure.

In 2018, Nelson completed a record-breaking 735th shift as a flight director at Mission Control.

The human body undergoes specific challenges in space. A new film from TRISH explains the unique phenomenon and how research is helping to improve human life in space. Photo courtesy of NASA

Houston-based organization premieres space health tech documentary

watch now

A Houston space health organization has launched a film that is available to anyone interested in how space affects the human body.

The Translational Research Institute for Space Health, or TRISH, which is housed out of Baylor College of Medicine in consortium with Caltech and the Massachusetts Institute of Technology, announced a new documentary — “Space Health: Surviving in the Final Frontier.” The film, which covers how space affects humans both physically and mentally. It's free to watch online.

“This documentary provides an unprecedented look into the challenges – physical and mental – facing space explorers and the types of innovative research that TRISH supports to address these challenges,” says Dr. Dorit Donoviel, TRISH executive director and associate professor in Baylor’s Center for Space Medicine, in a news release. “We hope the film inspires students and researchers alike to see how their work could one day soon improve the lives of human explorers.”

The documentary interviews a wide range of experts — scientists, flight surgeons, astronauts, etc. — about all topics related to health, like food, medicine, radiation, isolation, and more. Some names you'll see on the screen include:

  • Former NASA astronaut Nicole Stott
  • Active NASA astronaut Victor Glover
  • NASA Associate Administrator Kathy Lueders
  • Inspiration4 Commander Jared Issacman
  • TRISH-funded researchers Level Ex CEO Sam Glassenberg and Holobiome CEO Philip Strandwitz

“Understanding and solving the challenges that face humans in space is critical work,” says Dr. Jennifer Fogarty, TRISH chief scientific officer, in the release. “Not only does space health research aim to unlock new realms of possibility for human space exploration, but it also furthers our ability to innovate on earth, providing insights for healthcare at home.”

TRISH is funded by NASA’s Human Research Program and seeks both early stage and translation-ready research and technology to protect and improve the health and performance of space explorers. This film was enabled by a collaboration with NASA and HRP.

Orion — NASA's program that will take astronauts to the moon by 2024 — has a new leader. Photo courtesy of NASA

NASA names new female exec to human spaceflight program

ready for take off

NASA is preparing to return to the moon by 2024 — and the organization just tapped the woman who will lead the program.

Catherine Koerner was announced last week as the manager of NASA's Orion Program, the spacecraft that will be used for the moon-bound Artemis missions. According to a press release, Koerner's position was effective Tuesday, September 8, and will be based at NASA's Johnson Space Center in Houston.

"I'm honored to be selected as the Orion Program Manager. Orion is a key element of the agency's Artemis infrastructure, and I look forward to leading the team responsible for developing and building America's deep space human spacecraft," Koerner says in the release. "Next year we'll be launching the Artemis I test flight — a major milestone — and the first of the Artemis mission series on our way to putting the first woman and the next man on the Moon."

Catherine Koerner is leading the Orion Program from Houston's Johnson Space Center. Photo courtesy of NASA

Prior to this position, Koerner led the Human Health and Performance Directorate team at Johnson, and she's also served as flight director, space shuttle manager for the Missions Operations Directorate, deputy manager of the Vehicle Office and manager of the Transportation Integration Office for the International Space Station Program, per the release.

In her new role, Koerner will be oversee design, development, and testing for the Orion spacecraft and any other ongoing projects within the program.

"Cathy brings to Orion a diverse background in engineering and human health, two key components for the Artemis program that will see the spacecraft send our astronauts to the Moon, ushering in a sustainable presence on the lunar surface," says Kathy Lueders, NASA's associate administrator for human exploration and operations, in the release. "Working with our partners, her leadership will guide the program to achievements that will inspire and benefit humanity."

Lueders was recently named to her position in June, and both these appointments are a part of NASA's plans to scale its human spaceflight team. NASA also just called for recruitment in Mission Control at JSC.

"Cathy brings 30 years of human spaceflight experience to the challenging task of managing the Orion program," says JSC Director Mark Geyer in the release. "I am confident she will lead Orion into flight and into a sustainable future."



Koerner succeeds Mark Kirasich, who is currently leading NASA's Advanced Exploration Systems Division in the Human Exploration and Operations Mission Directorate at NASA Headquarters. Howard Hu, who was acting Orion program manager, will serve as Orion deputy program manager.

Orion, the Space Launch System (SLS), and Exploration Ground Systems programs are foundational elements of NASA's Artemis program. Artemis I will be the first integrated flight test of Orion and the SLS next year. Artemis II will follow as the first human mission, taking astronauts farther into space than ever before. On Artemis III, astronauts will set foot on the Moon by 2024.

NASA is now hiring. Photo via nasa.gov

NASA is hiring flight directors at Houston's Johnson Space Center

mission control

NASA has put out the virtual "now hiring" sign at Johnson Space Center. United States citizens have until Thursday, September 10, to apply for the position of flight director.

Now that American astronauts are once again launching off from American soil, NASA is amping up its flight director staff, according to a news release. Applications are open online for the flight director position, which oversees flights to the International Space Station from mission control at JSC.

"NASA flight directors need a unique mixture of confidence and humility, innovation and organization," says Holly Ridings, chief flight director at JSC, in the release. "The situations you have to deal with are occasionally very tough, and the stakes are always very high. But if you are able to handle that responsibility, there is nothing like knowing that you played a key role in the historic work that NASA does on a day-to-day basis."

Flight director candidates must be U.S. citizens and have a bachelor's degree from an accredited institution in engineering, biological science, physical science, computer science, or mathematics, per the release. Additionally, they also will need related experience — more details are available online.

The selected flight director hires will be announced later in the fall, and then will begin extensive training with NASA.

This summer, NASA and SpaceX's launch of astronauts Robert Behnken and Douglas Hurley market the first American liftoff in nearly a decade.

Following the mission, NASA named its new human spaceflight director, Kathy Lueders. In that announcement, NASA Administrator Jim Bridenstine alluded to the missions that are in the works for human spaceflight.

"We have our sights set on the Moon and even deeper into space, and Kathy is going to help lead us there," Bridenstine said.

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Houston doctor aims to revolutionize hearing aid industry with tiny implant

small but mighty

“What is the future of hearing aids?” That’s the question that led to a potential revolution.

“The current hearing aid market and technology is old, and there are little incremental improvements, but really no significant, radical new ideas, and I like to challenge the status quo,” says Dr. Ron Moses, an ENT specialist and surgeon at Houston Methodist.

Moses is the creator of NanoEar, which he calls “the world’s smallest hearing aid.” NanoEar is an implantable device that combines the invisibility of a micro-sized tympanostomy tube with more power—and a superior hearing experience—than the best behind-the-ear hearing aid.

“You put the NanoEar inside of the eardrum in an in-office procedure that takes literally five minutes,” Moses says.

As Moses explains, because of how the human cochlea is formed, its nerves break down over time. It’s simply an inevitability that if we live long enough, we will need hearing aids.

“The question is, ‘Are we going to all be satisfied with what exists?’” he asks.

Moses says that currently, only about 20 percent of patients who need hearing aids have them. That’s because of the combination of the stigma, the expense, and the hassle and discomfort associated with the hearing aids currently available on the market. That leaves 80 percent untapped among a population of 466 million people with hearing impairment, and more to come as our population ages. In a nearly $7 billion global market, that additional 80 percent could mean big money.

Moses initially patented a version of the invention in 2000, but says that it took finding the right team to incorporate as NanoEar. That took place in 2016, when he joined forces with cofounders Michael Moore and Willem Vermaat, now the company’s president and CFO, respectively. Moore is a mechanical engineer, while Vermaat is a “financial guru;” both are repeat entrepreneurs in the biotech space.

Today, NanoEar has nine active patents. The company’s technical advisors include “the genius behind developing the brains in this device,” Chris Salthouse; NASA battery engineer Will West; Dutch physicist and audiologist Joris Dirckx; and Daniel Spitz, a third-generation master watchmaker and the original guitarist for the famed metal band Anthrax.

The NanoEar concept has done proof-of-concept testing on both cadavers at the University of Antwerp and on chinchillas, which are excellent models for human hearing, at Tulane University. As part of the TMC Innovation Institute program in 2017, the NanoEar team met with FDA advisors, who told them that they might be eligible for an expedited pathway to approval.

Thus far, NanoEar has raised about $900,000 to get its nine patents and perform its proof-of-concept experiments. The next step is to build the prototype, but completing it will take $2.75 million of seed funding.

Despite the potential for making global change, Moses has said it’s been challenging to raise funds for his innovation.

“We're hoping to find that group of people or person who may want to hear their children or grandchildren better. They may want to join with others and bring a team of investors to offset that risk, to move this forward, because we already have a world-class team ready to go,” he says.

To that end, NanoEar has partnered with Austin-based Capital Factory to help with their raise. “I have reached out to their entire network and am getting a lot of interest, a lot of interest,” says Moses. “But in the end, of course, we need the money.”

It will likely, quite literally, be a sound investment in the future of how we all hear the next generation.

Houston VC funding surged in Q1 2025 to highest level in years, report says

by the numbers

First-quarter funding for Houston-area startups just hit its highest level since 2022, according to the latest PitchBook-NVCA Venture Monitor. But fundraising in subsequent quarters might not be as robust thanks to ongoing economic turmoil, the report warns.

In the first quarter of 2025, Houston-area startups raised $544.2 million in venture capital from investors, PitchBook-NVCA data shows. That compares with $263.5 million in Q1 2024 and $344.5 million in Q1 2023. For the first quarter of 2022, local startups nabbed $745.5 million in venture capital.

The Houston-area total for first-quarter VC funding this year fell well short of the sum for the Austin area (more than $3.3 billion) and Dallas-Fort Worth ($696.8 million), according to PitchBook-NVCA data.

While first-quarter 2025 funding for Houston-area startups got a boost, the number of VC deals declined versus the first quarters of 2024, 2023 and 2022. The PitchBook-NVCA Monitor reported 37 local VC deals in this year’s first quarter, compared with 45 during the same period in 2024, 53 in 2023, and 57 in 2022.

The PitchBook-NVCA report indicates fundraising figures for the Houston area, the Austin area, Dallas-Fort Worth and other markets might shrink in upcoming quarters.

“Should the latest iteration of tariffs stand, we expect significant pressure on fundraising and dealmaking in the near term as investors sit on the sidelines and wait for signs of market stabilization,” the report says.

Due to new trade tariffs and policy shifts, the chances of an upcoming rebound in the VC market have likely faded, says Nizar Tarhuni, executive vice president of research and market intelligence at PitchBook.

“These impacts amplify economic uncertainty and could further disrupt the private markets by complicating investment decisions, supply chains, exit windows, and portfolio strategies,” Tarhuni says. “While this may eventually lead to new domestic investment and create opportunities, the overall environment is facing volatility, hesitation, and structural change.”