The Department of Energy has doled out funding to four Houston companies. Photo via Getty Images

Four Houston companies have captured more than $45 million in federal funding to promote the capture, transportation, use, and storage of tons of carbon dioxide emissions.

The U.S. Department of Energy on May 17 announced funding for these four Houston companies:

  • BP Corporation North America Inc. — $33,411,193. The money will be earmarked for two commercial-scale storage sites along the Texas Gulf Coast. The sites will be able to ultimately store up to 15 million metric tons of CO2 per year.
  • Timberlands Sequestration LLC — $23,779,020. The funding will go toward a biomass carbon removal and storage project for the Alabama River Cellulose pulp and paper mill in Monroe County, Alabama. Atlanta-based Georgia-Pacific LLC owns the mill.
  • Magnolia Sequestration Hub LLC — $21,570,784. The money will help finance the Magnolia Sequestration Hub in Allen Parish, Louisiana, with an estimated 300 million metric tons of total CO2 storage capacity. Magnolia is a subsidiary of Houston-based Occidental Petroleum Corp.
  • Bluebonnet Sequestration Hub LLC — $16,480,117. The funding will be spent on development of the Bluebonnet Sequestration Hub along the Texas Gulf Coast, with the potential for more than 350 million metric tons of CO2 storage capacity. Bluebonnet is a subsidiary of Occidental.

Another Texas company received $3 million in Department of Energy (DOE) funding. Howard Midstream Energy Partners LLC of San Antonio will perform a study for a system capable of moving up to 250 million metric tons of CO2 per year from numerous sources to storage sites on the Gulf Coast — from the Port of Corpus Christi to the Mississippi River.

In all, the Department of Energy announced $251 million in funding for 12 projects in seven states aimed at bolstering the U.S. carbon management capabilities. The money comes from the federal Infrastructure Investment and Jobs Act, which was enacted in 2021.

“Thanks to historic clean energy investments, DOE is building out the infrastructure needed to slash harmful carbon pollution from industry and the power sector, revitalize local economies, and unlock enormous public health benefits,” U.S. Energy Secretary Jennifer Granholm says in a news release.

DOE says carbon dioxide emissions are fueling global warming, which has heightened the threat of droughts, severe fires, rising sea levels, floods, catastrophic storms, and declining biodiversity.

Precedence Research estimates the value of the global market for carbon capture and storage was $4.91 billion in 2022, and it expects the market value to reach $35.7 billion by 2032.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.