Baylor College of Medicine's Jessica Watts, Dr. Jerome Pollet, and Dr. Paul Ling with Tess. Photo by Jackelin Reyna/Houston Zoo

An innovative team from Baylor College of Medicine and Texas Children’s Hospital has worked with the Houston Zoo to develop a first-of-its-kind treatment for elephants, which has been administered to its first patient.

Tess, the beloved, 40-year-old matriarch of the Houston Zoo’s elephant herd, is recovering well after receiving the first-ever mRNA vaccine against elephant endotheliotropic herpesvirus (EEHV) 1A on Tuesday, June 18. The veterinary staff at the Houston Zoo will monitor Tess in the coming weeks to check her reaction and the efficacy of the vaccine.

EEHV 1A is a deadly infection for Asian Elephants. While generally benign in African Elephants, Asian Elephants can develop fatal hemorrhages. The fatality rate is a whopping 80 percent, making it one of the most serous threats to elephant populations outside of humans.

Anti-viral drugs have some effect on the disease, but two-thirds show no improvement. This has led to a search for a vaccine. For 15 years, the Houston Zoo and Dr. Paul Ling at Baylor College of Medicine’s Department of Virology and Microbiology have partnered to develop the drug. They have been helped by worldwide research from zoos and animal specialists, as well as graduate student Jessica Watts and Dr. Jeroen Pollet at Houston's Texas Children’s Hospital. The research has been funded by private donations, research partnerships, and grants.

Before being inoculated, the mRNA vaccine was exhaustively tested, with the dosage being extrapolated from data involving horses.

Houston Zoo veterinarians will periodically test Tess to see if she is developing the appropriate antibodies. If she is and there are no adverse reactions, the next step will be to administer the vaccine to the rest of the Houston herd. Many of these are Tess’s own children (Tucker, Tupelo, Tilly, and Teddy) and grandchildren (Winnie).

Should the vaccine prove effective, the doses will be made available worldwide to zoos and private elephant sanctuaries. It is likely to have a significant benefit on protecting and preserving the Asian Elephant population. As of January, there are fewer than 50,000 of the animas left in the wild. They are currently listed as endangered, and breeding programs and research done through the Houston Zoo are essential to keeping the animals from going extinct.

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This article originally ran on CultureMap.

The immersive new exhibit will now open next year. Image courtesy of Houston Zoo

Houston Zoo delays new, immersive island exhibit due to supply chain issues

journey delayed

Houstonians eager to meet sea lions, giant tortoises, sharks, and Humboldt penguins at the Houston Zoo will have to wait a bit longer, the zoo announced.

Galápagos Islands, the highly immersive Houston Zoo experience showcasing one of the most pristine, ecologically rich areas in the world, will not open until early 2023.

The Galápagos exhibit is part of the zoo’s 100th anniversary celebration and was slated to open fall of this year. Zoo officials cite supply chain issues for key construction materials — such as acrylic viewing panels for the state-of-the-art sea lion habitat — as the reason for the delay.

This planned exhibit is the first of its kind to showcase the wildlife of the legendary island chain that Charles Darwin studied and made famous.Guests can dive into an environment evoking the archipelago’s unique landscapes and oceanic habitats — all meant to inspire intrigue and preservation.

One major draw should be the Galápagos penguins, which are threatened by overfishing, ocean pollution, and climate change and are highly protected by the Ecuadorian government. It is the most threatened penguin species in the world, the zoo notes, with an estimated population of less than 2,000 individuals.

The Galápagos is often heralded as the planet’s ultimate area spotlighting unique species, the delicate balance of ecosystems, and the pressing need for conservation action, the zoo notes.

“We’re disappointed that the project has been delayed, but we know we’re not alone in experiencing supply chain problems,” said Houston Zoo president and CEO Lee Ehmke in a statement. “Our commitment to conservation in the Galápagos Islands, our animal residents, and our guests here in Houston remain unwavering. A short delay in our exhibit opening will not deter us from our mission of connecting communities to animals, inspiring action to save wildlife.”

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This article originally ran on CultureMap.

Memorial Park, which is currently undergoing a master plan renovation, and other Houston parks can be a great opportunity for introducing urban conservation inside the city limits. Rendering courtesy of Nelson Byrd Woltz

Houston conservationist is helping to find new ways to protect local species and ecosystems

Living on a prairie

The Houston toad is a species that was discovered in Harris County in the 1950s. It has a very distinct, loud call that reverberates at quite a high pitch. But the Houston toad's call hasn't been heard in the city of Houston for almost 50 years. The species is locally extinct and critically endangered elsewhere. In fact, it's the most endangered amphibian in North America, says Cassidy Brown Johnson, a Rice University lecturer and president of the Coastal Prairie Partnership.

"When we think about extinction, we think of the dodo bird or the woolly mammoth," Johnson says. "But extinction is happening right underneath our noses."

The Houston Zoo has a breeding facility for Houston toad, but other than that, it's extremely unlikely that the Houston toad will ever reside naturally in its namesake city.

"We have modified the environment so heavily, that it'd be a bit of a dicey thing to do [to reintroduce the species] because there are so few of them, it's better to focus on an environment where it's still OK for them," Johnson says. The largest population of the Houston toad is actually in Bastrop, however due to the Bastrop fires in 2011, the species is only just recently back to a good place even there.

Johnson is giving a free lecture in April at Rice regarding extinction, where she'll bring her Astros-named Houston toads, Springer and Julia Morales, as her teacher aids.

Changing tides in conservation
As cities like Houston continue to be developed, scientists and researchers are challenged with finding new ways to effect conservation. Johnson says within the industry, there's been a shift in thinking when it comes to preserving nature.

"There's a new burgeoning movement in conservation called urban conservation," she says. "For a long time, if you talked to the traditional conservationists, the idea of conservation is to protect big spaces — the national and state park systems are the perfect example."

But large parks are expensive and a huge undertaking. It's still the strongest form of conservation, but introducing conservation efforts in a city — perhaps in some of Houston's parks, like Memorial Park or Hermann Park — helps not only the species of animals involved, but also educates the local population and forms a connection with residents.

"That has a twofold kind of benefit," Johnson says. "It protects the greenspace so species to live with us, and then also it makes the connection to this place we try to protect."

Of course, this type of effort is new, and there's not a lot of data to show how this would affect the ecosystem and its species, from the migratory and genetic diversity standpoints. Despite the lack of data, Johnson says this type of effort needs to happen.

"We're going to continue to manipulate the world, and maybe if we started thinking about this now, that we can get to a point were we understand enough were we can make these some sort of functioning ecosystem," she says.

Part of the shift in thinking about these ecosystems has to do with new ways of tracking species and understanding their environments.

"Technology is helping us ask a lot of these questions," Johnson says. "Ecology is surprisingly complicated. There's so many variables. ... I think technology and our advance with computing is definitely going to help us understand it."

Using preservation to solve flooding
The educational component is also very important to conservation, and Johnson is making strides on campus with her class. Last year, her department and her class introduced a pocket prairie right on the Rice campus.

Before it was the fourth largest city in America, Houston was a prairie. That type of ecosystem — thick with prairie grass — is very absorbing when it comes to rain water.

"It's really surprising to people that the trees and all this lushness is actually all artificial," Johnson says. "We know that this ecosystem evolved with the cyclical flooding events that happened here."

This movement to bring back Houston's ancient ecosystem is a new focus on a few prairie conservationist groups — and even the Harris County Flood Control. This has been going on for a while, but recent flooding events have opened the eyes of people now looking for reliable solutions to flooding problems.

"After Hurricane Harvey, people started realizing that this might be one of the solutions we could actually investigate and see if it can help us," Johnson says. "A green space is going to absorb way more water than a parking lot."

Of course, there are other flood solutions being discussed — some even incorporating tech or even a tube system underground.

"Historically, there has been some budding of heads between the environment and technology, but I really think moving forward, those two fields have to work together. We need to use technology to save the environment," Johnson says. "I think Houston is one of the places where that conversation is starting to happen."

Missing the toads

Courtesy of Cassidy Brown Johnson

The Houston toad has been locally extinct since the 1970s.

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Bristol Myers Squibb to build $2.3B Houston pharma manufacturing campus

coming soon

New Jersey-based pharmaceutical giant Bristol Myers Squibb Co. has officially named Houston as the home of its new state-of-the-art manufacturing site.

The 60,000-square-foot facility represents a $2.3 billion investment, according to a news release. It is expected to create 500 skilled jobs and will be located in Houston's Generation Park.

BMS first announced that it was considering Houston among 16 other cities for the facility in May. The new hub will manufacture small molecule, biologic and antibody-drug conjugates and is part of a $40 billion commitment to invest in the United States over five years. Construction is slated to begin next year, with the facility coming online in 2030.

"We're building the domestic manufacturing capabilities needed to deliver the next generation of medicines and support future scientific breakthroughs. Houston and the state of Texas offer the talent, infrastructure, and partnership needed to help bring that vision to life," Christopher Boerner, CEO and board chair of BMS, said in the release.

The new facility will feature a modular, multi-modal design, which will allow the company to reconfigure and add to its manufacturing capabilities over time. BMS says it expects the facility to "(grow) in scale and capability well beyond its opening configuration."

"Our decision to build this state-of-the-art manufacturing campus in Houston, Texas, reflects our confidence in the region’s ability to support a world-class, digitally advanced supply operation,” Karin Shanahan, EVP and chief supply chain and operations officer of BMS, added in the release. “This facility is designed to deliver the speed, quality, and reliability that patients depend on, combining flexible, modular manufacturing with advanced digital capabilities to ensure consistent supply across multiple modalities. It strengthens our ability to operate with resilience and positions us to reliably deliver medicines to patients today while adapting future demands.”

Texas Gov. Greg Abbott shared that the state has granted BMS a $4.89 million Texas Enterprise Fund (TEF) grant for the project. TEF grants, administered by the Texas Economic Development & Tourism Office, support business relocation or expansion projects that create "new, good-paying jobs in the community and attract significant new capital investment to the state." The development is also a qualified project under the Texas Jobs, Energy, Technology, and Innovation (JETI) program.

“Texas is a global hub for life sciences, where today’s innovations shape the future of healthcare,” Abbott said in a news release. “This $2.3 billion investment by Bristol Myers Squibb in the dynamic biotech ecosystem in Houston is a testament to the depth of our skilled workforce and the pipeline of talent coming through our nation-leading technical colleges and research universities. With lower operating costs and easy access to markets across the U.S. and the world, Texas drives affordability for consumers.”

"Bristol Myers Squibb’s announcement is a tremendous win for Texas and the Houston region, further reinforcing our position as a premier destination for life sciences and advanced manufacturing,” added Greater Houston Partnership President and CEO Steve Kean.

Last fall, Eli Lilly and Co. selected Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.

Texas foundation makes massive $180M donation to Galveston hospital

historic gift

The University of Texas Medical Branch in Galveston (UTMB) has accepted a staggering $130 million grant from the Sealy & Smith Foundation, which, combined with the $50 million that the foundation donated in 2025 to establish the Department of Cardiovascular Medicine, is the largest bequest in UTMB history.

The grant will go to grow cardiovascular imaging, diagnosis, and treatment at UTMB by establishing an inpatient cardiovascular hub on the sixth floor of Jennie Sealy Hospital. In honor of the donation, the department is being renamed the Sealy Heart and Vascular Institute.

“The Sealy & Smith Foundation has a long history of investing in initiatives that transform health care for the people of Galveston and beyond,” said John Kelso, president of The Sealy & Smith Foundation Board of Directors. “We believe the Sealy Heart & Vascular Institute has the potential to redefine cardiovascular care in our region by bringing together exceptional physicians, advanced technology, innovative research and a commitment to improving patient outcomes. This additional investment reflects our confidence in UTMB’s vision and our belief that the Institute will have a lasting impact for generations to come.”

The Sealy & Smith Foundation was established in 1922 by John Sealy II and his sister Jennie Sealy Smith. Bolstered by the Sealy fortune built on shipping, oil, banking, and railroads, the Foundation has donated more than $1.2 billion to UTMB over the last century, linking the family legacy to healthcare, teaching, and research. It was John Sealy Sr. who contributed the initial $50,000 to build a hospital on the island, which opened right alongside the new medical school created by the state legislator in what was then Texas's largest and most economically powerful city.

Since then, the Foundation has helped grow UTMB into a world-class hospital. The cardiovascular care especially is well-regarded, making the 2025 Newsweek/Statista List of America's Best Hospitals.

“This extraordinary investment reflects The Sealy & Smith Foundation’s unwavering commitment to improving health and advancing medical excellence,” said Dr. Jochen Reiser, UTMB president and CEO of the UTMB Health System. “The partnership between UTMB and The Sealy & Smith Foundation is very strong. Built on generations of shared vision and trust, it continues to redefine what an academic health system can achieve. Together, we are building one of the nation’s premier cardiovascular programs integrating exceptional patient care, groundbreaking research, innovation and world-class education to improve the lives of patients throughout Texas and beyond.”

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This article originally appeared on CultureMap.com.

UTHealth Houston team joins NASA initiative to protect border drinking water

water watch

Climate change means far more to public health than living with hotter days. Transformations in our weather are contributing to challenges in accessing safe drinking water in some communities.

One of the most dire situations is along the US–Mexico border. The National Aeronautics and Space Administration (NASA) is seeking to address that issue with its Water Quality Applications program. An 11-researcher project led by a UTHealth Houston School of Public Health faculty member has been selected to participate.

“Drinking water is one of the most fundamental public health protections, but producing safe drinking water involves a delicate balance,” Yun Hang, assistant professor of environmental and occupational health sciences, said in a news release. Her team’s proposal was one of 93 that were submitted for funding through NASA’s Research Opportunities in Space and Earth Sciences (ROSES)-2025 program.

This is the first time that NASA has worked with a team devoted to water quality applications. The group, which includes researchers from across the nation, will use satellite observations of Earth, as well as hydrologic modeling, to potentially anticipate and act on water quality conditions as they change. Challenges addressed over the course of the three-year program, which kicked off in June, might include problems with water quality due to climate variability and increased pressure on water resources.

Hang’s team will focus on a pair of borderlands: Paso del Norte and the Rio Grande Valley.

“Working closely with El Paso Water ensures that our research addresses real operational needs while helping utilities better prepare for climate-related water quality changes and continue providing safe drinking water to communities across the Texas border region,” Hang added in the release.

She and the team will use data gathered by NASA on both past and future Earth-observing missions, which will allow them to track environmental changes that may affect source water quality. Combined with past water treatment records and hydrologic models, the team will also utilize artificial intelligence to develop predictive tools that aim to stop issues before they become larger hurdles to water safety.

Another one of the project’s goals is to create visualization tools and source water summaries that can be utilized by those without scientific expertise. The tools will be produced in English and Spanish to further broaden their accessibility.

The hope is that the materials made by the team will also go far beyond the border, with protocols that can be adapted or adopted by other areas dealing with water quality issues.