Houstonians live well. Photo via Getty Images

A new economic analysis by the Ludwig Institute for Shared Economic Prosperity (LISEP) has revealed that Houston-The-Woodlands-Sugar Land has the 30th most prosperous local economy in the nation. The analysis ranked the 50 largest Metropolitan Statistical Areas (MSAs) in the U.S. based on several localized economic factors.

According to Houston's data, the region's population has skyrocketed 18.7 percent within the last decade, now reaching over 7.34 million people. The median age of an Houston-area resident is 35.1-years-old.

The three main criteria that determined Houston's prospering rank include a "True Living Cost" metric that tracks price changes for essential household necessities; a "True Weekly Earnings" calculation that determines the median weekly earnings of all workers (including part-timers and those who are unemployed); and a "True Rate of Unemployment Out of the Population" metric that measures the percentage of people unable to find full-time employment with a living wage.

The findings show that a little more than half of all Houston-area households are earning enough income to afford their basic needs. The remaining 46.4 percent are struggling due to a high cost of living, the report said.

"The total costs of necessities for a 4-person family [in Houston-The Woodlands-Sugar Land] increased 58.2 percent since 2005 from $54,052 to $85,492," the report said.

Furthermore, Houstonians are bringing home higher weekly earnings than they were in 2020. Houston workers are earning a median $894.89 per week, or about $47,429.17 a year. The report states the average employee has gained 8.2 percent more purchasing power since 2005, and the average Houston household has 8.1 percent of their income leftover after their necessities.

Houston's "True Rate of Unemployment Out of the Population" is 63 percent, according to the analysis.

The objective behind LISEP's report is to help policymakers assess their local economies' dynamics and to assess how much low-income and working-class families are affected, according to LISEP Chairman Gene Ludwig in the release.

"Across the nation we are seeing both ends of the spectrum — communities where middle- and working-class families are faring well and others where financial survival remains a struggle," Ludwig said. "Our challenge here is in identifying what's working well and replicating it; what's not, and scrapping it. This is where real-world data can be invaluable to policymakers."

Houston-The Woodlands-Sugar Land wasn't the only Texas metro area to earn a spot in the analysis. Austin-Round Rock worked its way up into No. 2 nationally, while San Antonio-New Braunfels ranked just outside the top 10 at No. 13. Dallas-Fort Worth-Arlington ranked four spots higher than Houston at No. 26.

The top 10 highest-performing economies in the U.S. are:

  • No. 1 – San Jose-Sunnyvale, Santa Clara, California
  • No. 2 – Austin-Round Rock, Texas
  • No. 3 – San Francisco-Oakland-Hayward, California
  • No. 4 – Baltimroe-Columbia-Towson, Maryland
  • No. 5 – Washington-Arlington-Alexandria, District of Columbia-Virginia-Maryland
  • No. 6 – Minneapolis-St. Paul-Blookington, Minnesota-Wisconsin
  • No. 7 – Portland-Vancouver-Hillsboro, Oregon-Washington
  • No. 8 – Milwaukee-Waukesha-West Allis, Wisconsin
  • No. 9 – Denver-Aurora-Lakewood, Colorado
  • No. 10 – Salt Lake City, Utah
The full report and its methodology can be found on lisep.org.

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This article originally ran on CultureMap.

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Houston biotech co. raises $11M to advance ALS drug development

drug money

Houston-based clinical-stage biotechnology company Coya Therapeutics (NASDAQ: COYA) has raised $11.1 million in a private investment round.

India-based pharmaceuticals company Dr. Reddy’s Laboratories Inc. led the round with a $10 million investment, according to a news release. New York-based investment firm Greenlight Capital, Coya’s largest institutional shareholder, contributed $1.1 million.

The funding was raised through a definitive securities purchase agreement for the purchase and sale of more than 2.5 million shares of Coya's common stock in a private placement at $4.40 per share.

Coya reports that it plans to use the proceeds to scale up manufacturing of low-dose interleukin-2 (IL-2), which is a component of its COYA 302 and will support the commercial readiness of the drug. COYA 302 enhances anti-inflammatory T cell function and suppresses harmful immune activity for treatment of Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s disease and Alzheimer’s disease.

The company received FDA acceptance for its investigational new drug application for COYA 302 for treating ALS and FTD this summer. Its ALSTARS Phase 2 clinical trial for ALS treatment launched this fall in the U.S. and Canada and has begun enrolling and dosing patients. Coya CEO Arun Swaminathan said in a letter to investors that the company also plans to advance its clinical programs for the drug for FTD therapy in 2026.

Coya was founded in 2021. The company merged with Nicoya Health Inc. in 2020 and raised $10 million in its series A the same year. It closed its IPO in January 2023 for more than $15 million. Its therapeutics uses innovative work from Houston Methodist's Dr. Stanley H. Appel.

New accelerator for AI startups to launch at Houston's Ion this spring

The Collectiv Foundation and Rice University have established a sports, health and wellness startup accelerator at the Ion District’s Collectiv, a sports-focused venture capital platform.

The AI Native Dual-Use Sports, Health & Wellness Accelerator, scheduled to formally launch in March, will back early-stage startups developing AI for the sports, health and wellness markets. Accelerator participants will gain access to a host of opportunities with:

  • Mentors
  • Advisers
  • Pro sports teams and leagues
  • University athletics programs
  • Health care systems
  • Corporate partners
  • VC firms
  • Pilot projects
  • University-based entrepreneurship and business initiatives

Accelerator participants will focus on sports tech verticals inlcuding performance and health, fan experience and media platforms, data and analytics, and infrastructure.

“Houston is quickly becoming one of the most important innovation hubs at the intersection of sports, health, and AI,” Ashley DeWalt, co-founder and managing partner of The Collectiv and founder of The Collectiv Foundation, said in a news release.

“By launching this platform with Rice University in the Ion District,” he added, “we are building a category-defining acceleration engine that gives founders access to world-class research, global sports properties, hospital systems, and venture capital. This is about turning sports-validated technology into globally scalable companies at a moment when the world’s attention is converging on Houston ahead of the 2026 World Cup.”

The Collectiv accelerator will draw on expertise from organizations such as the Rice-Houston Methodist Center for Human Performance, Rice Brain Institute, Rice Gateway Project and the Texas Medical Center.

“The combination of Rice University’s research leadership, Houston’s unmatched health ecosystem, and The Collectiv’s operator-driven investment platform creates a powerful acceleration engine,” Blair Garrou, co-founder and managing partner of the Mercury Fund VC firm and a senior adviser for The Collectiv, added in the release.

Additional details on programming, partners and application timelines are expected to be announced in the coming weeks.

4 Houston-area schools excel with best online degree programs in U.S.

Top of the Class

Four Houston-area universities have earned well-deserved recognition in U.S. News & World Report's just-released rankings of the Best Online Programs for 2026.

The annual rankings offer insight into the best American universities for students seeking a flexible and affordable way to attain a higher education. In the 2026 edition, U.S. News analyzed nearly 1,850 online programs for bachelor's degrees and seven master's degree disciplines: MBA, business (non-MBA), criminal justice, education, engineering, information technology, and nursing.

Many of these local schools are also high achievers in U.S. News' separate rankings of the best grad schools.

Rice University tied with Texas A&M University in College Station for the No. 3 best online master's in information technology program in the U.S., and its online MBA program ranked No. 21 nationally.

The online master's in nursing program at The University of Texas Medical Branch in Galveston was the highest performing master's nursing degree in Texas, and it ranked No. 19 nationally.

Three different programs at The University of Houston were ranked among the top 100 nationwide:
  • No. 18 – Best online master's in education
  • No. 59 – Best online master's in business (non-MBA)
  • No. 89 – Best online bachelor's program
The University of Houston's Clear Lake campus ranked No. 65 nationally for its online master's in education program.

"Online education continues to be a vital path for professionals, parents, and service members seeking to advance their careers and broaden their knowledge with necessary flexibility," said U.S. News education managing editor LaMont Jones in a press release. "The 2026 Best Online Programs rankings are an essential tool for prospective students, providing rigorous, independent analysis to help them choose a high-quality program that aligns with their personal and professional goals."

A little farther outside Houston, two more universities – Sam Houston State University in Huntsville and Texas A&M University in College Station – stood out for their online degree programs.

Sam Houston State University

  • No. 5 – Best online master's in criminal justice
  • No. 30 – Best online master's in information technology
  • No. 36 – Best online master's in education
  • No. 77 – Best online bachelor's program
  • No. 96 – Best online master's in business (non-MBA)
Texas A&M University
  • No. 3 – Best online master's in information technology (tied with Rice)
  • No. 3 – Best online master's in business (non-MBA)
  • No. 8 – Best online master's in education
  • No. 9 – Best online master's in engineering
  • No. 11 – Best online bachelor's program
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This article originally appeared on CultureMap.com.