Good things don't just come to those who wait. If you're wanting to get your startup in front of major corporations, you need to take matters into your own hands. Pexels

If you've ever wanted to know the best way to get your startup in front of a major corporation, according to experts from both sides of the table — here's your chance.

At the Houston Innovation Open Conference, five major players in Houston's innovation ecosystem sat on a panel and discussed startups, accelerators, and more. One question asked each panelist for their advice for corporate partnerships. Here's what they had to say.

“Go to one of our programs — even if you used to work at an oil and gas company, as a startup, you need new pathways and you need help and support and lots of love along the way.”

Gabriella Rowe, CEO of Station Houston. Even with a Houston business background, there's strength in numbers, she says.

“Keep your identity along the way.”

Haibin Xu, regional manager of Shell Research Connect & GameChanger US and Canada. From the corporate side of things. Xu said sometimes the Shells of the world can't help you — find the right company that best aligns with your startup.

“Do your research. … And have a clear value proposition, and put it on the table.”

Wade Bitaraf, head of energy and sustainability practice at Plug and Play. Preparation and research is extremely important before you meet with any potential corporate partners.

“Find a community to join … and don’t limit yourself to what you think is your industry.”

Brad True, managing director of The Cannon and Cannon Ventures. True gave an example of a Cannon company that found success outside the industry they thought they were confined to.

“You have to find the pathways that are going to make it as easy as possible.”

Brian Richards, innovation lead and managing director at Accenture. Richards emphasized that startups can go bankrupt waiting for something formal from a big corporation.

Speakers at the third annual Houston Innovation Open Conference discussed policy, performance, and more. Photo by Zview/Getty Images

Overheard: 5 powerful quotes from Houstonians speaking at the Houston Open Innovation Conference

EAVESDROPPING IN Houston

When it comes to Houston's innovation ecosystem, there's a lot to discuss. From accelerator programs to role of educational institutes, the third annual Houston Open Innovation Conference covered it all on Thursday, March 28.

I had the pleasure of attending the full-day conference, which was a meeting of the minds of Houston innovation. To catch you up and rid you of your fear of missing out, check out these five overheard quotes from the day.

“I’ve charged my board on Houston Exponential, and I say to them, ‘What good is it for us to be the most diverse city in the country if we’re not solving the challenges that impact diverse communities.’”

Amanda Edwards, Houston City Council Member in At-Large Position 4, in her keynote presentation calling for Houston to lead the charge in solving inequalities in innovation.

“Competition is good. I would rather have an abundance of an ecosystem than just one (accelerator). I think each different group — whether it’s MassChallenge, Station Houston, or The Cannon or any other current or future accelerator — all has their own value proposition.”

Brian Richards, managing director, Accenture Houston Innovation Hub, during the panel about startups and entrepreneurs. The quote was in response to an audience question about competition within Houston accelerators and programs.

“If we don’t create this ecosystem, others will tap into the resources we have, and we lose or we fall short.”

Mayor Sylvester Turner, in his keynote presentation, explaining why the city is focused on developing the city's ecosystem now — before it's too late.

“I think the more emphasis on incubators and accelerators has addressed the need for community. You have people who are like minded … and you have a community that cares about something more deep rather than just being in the same physical space together.”

Grace Rodriguez, CEO and executive director of Impact Hub Houston, on the panel about accelerators and incubators. The panel question was regarding how some coworking spaces have evolved to be accelerator or incubator programs.

“This is such a uniquely positioned city because of its corporate base, because of the strength of its university structure, and because of the combination of that and the ability to collaborate within those two is a different kind of runway or opportunity.”

Susan Davenport, senior vice president, economic development at the Greater Houston Partnership, during the "Houston Innovation Ecosystem" panel.

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Austin company to bring AI-powered school to The Woodlands

AI education

Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”