TMC Innovation, Station Houston, and FanReact all made executive hires last week. Courtesy photos

It's been a busy week for Houston innovators. TMC Innovation Institute hired its new director, and Station Houston created a new director position — and filled it too. Plus, FanReact decided to divide and conquer its esports business, which meant a new executive hire.

Tom Luby, director of the TMC Innovation Institute

Tom Luby will run the Texas Medical Center's Innovation Institute. Courtesy of TMC

The Texas Medical Center has been searching for its new director over the past few months, but turns out, their pick was right next door at JLABS @ TMC serving as the site head. Tom Luby took the position, and has big plans to continue the institutes growth ahead of TMC3.

"What I hope to be helpful with is providing an overall strategic vision around TMC Innovation that allows us to scale from what's already been done here," Luby says in an InnovationMap interview.

Before moving to Houston, Luby worked in Boston's booming life sciences ecosystem. While it's not fair to compare Houston and Boston — a city that has had decades of growth in the space — he does note some similarities.

"If you roll the Boston tape back lets say 20 years where Boston was focused on generating a place where life science startups could have a chance to develop and be successful, that's where Houston is," Luby says. "We've gotten to a point where we're starting to see a really good density." Read more from the Tom Luby interview here.

Deanea LeFlore, director of community engagement, partnerships, and education at Station Houston

Deanea LeFlore is Station Houston's new director of community engagement, partnerships, and education. Courtesy of Station Houston

Station Houston hired Deanea LeFlore as director of community engagement, partnerships, and education. Previously, LeFlore served as chief of protocol for the city of Houston and a vice president of the Greater Houston Convention and Visitors Bureau.

"My passion is promoting Houston as a world-class place to invest, work and live, and I am thrilled to join an organization that embodies this same spirit," says LeFlore in a release. "Station's dedication to accelerating Houston's tech growth through collaboration and innovation compliments my professional experience and I look forward to opening our doors to new partners, expanding programming with our long-time supporters, and introducing Station to a new network of leaders." Read more about Station's new hire here.

Patrick Schneidau, CEO of RanReact

Chris Buckner (left), who has served as FanReact's CEO since its founding in 2014, will be the CEO of Mainline, and Patrick Schneidau has been hired to serve as CEO of FanReact. Photos courtesy

Houston-based FanReact has spun off its esports business as its own company, Mainline. Former FanReact CEO Chris Buckner will take the reins of the new business as CEO, and Patrick Schneidau has been hired as FanReact CEO.

Schneidau has has a long career in Houston's tech scene. He spent 12 years at Houston software company PROS and was on the leadership team when the company went public in 2007. Since he left his position as CMO at PROS, he served as the chair of the Talent Committee for Houston Exponential and serves on the board for InnovationMap.

"The Mainline business has been so successful in recent history, that it just made sense for us to dedicate resources toward building that market," Schneidau says. "The momentum in that market as a whole — and in Mainline specifically — is just too large to ignore and not put 100 percent of Chris' time in." Read more about the spinoff company here.

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Texas universities develop innovative open-source platform for cell analysis

picture this

What do labs do when faced with large amounts of imaging data? Powerful cloud computing systems have long been the answer to that question, but a new riposte comes from SPACe.

That’s the name of a new open-source image analysis platform designed by researchers at Baylor College of Medicine, Texas A&M University and the University of Houston.

SPACe, or Swift Phenotypic Analysis of Cells, was created to be used on standard computers that even small labs can access, meaning cellular analysis using images produced through cell painting has a lower barrier to entry than ever before.

“The pharmaceutical industry has been accustomed to simplifying complex data into single metrics. This platform allows us to shift away from that approach and instead capture the full diversity of cellular responses, providing richer, more informative data that can reveal new avenues for drug development,” Michael Mancini, professor of molecular and cellular biology and director of the Gulf Coast Consortium Center for Advanced Microscopy and Image Informatics co-located at Baylor College of Medicine and TAMU Institute for Bioscience and Technology.

SPACe is not only accessible because of its less substantial computational needs. Because the platform is open-source, it’s available to anyone who needs it. And it can be used by academic and pharmaceutical researchers alike.

“The platform allows for the identification of non-toxic effects of drugs, such as alterations in cell shape or effects on specific organelles, which are often overlooked by traditional assays that focus largely on cell viability,” says Fabio Stossi, currently a senior scientist with St. Jude Children’s Research Hospital, the lead author who was at Baylor during the development of SPACe.

The platform is a better means than ever of analyzing thousands of individual cells through automated imaging platforms, thereby better capturing the variability of biological processes. Through that, SPACe allows scientists an enhanced understanding of the interactions between drugs and cells, and does it on standard computers, translating to scientists performing large-scale drug screenings with greater ease.

"This tool could be a game-changer in how we understand cellular biology and discover new drugs. By capturing the full complexity of cellular responses, we are opening new doors for drug discovery that go beyond toxicity,” says Stossi.

And the fact that it’s open-source allows scientists to access SPACe for free right now. Researchers interested in using the platform can access it through Github at github.com/dlabate/SPACe. This early version could already make waves in research, but the team also plans to continually improve their product with the help of collaborations with other institutions.

The Ion names new coworking partner for Houston innovation hub

Where to Work

Rice University subsidiary Rice Real Estate Co. has tapped coworking company Industrious as the new operator of the Ion’s 86,000-square-foot coworking space in Midtown. Industrious replaces WeWork-owned Common Desk in that role.

The Ion, owned by Rice Real Estate and located at 4201 Main St., is a 266,000-square-foot office building and innovation hub in the 16-acre Ion District.

Features of the coworking space include private suites and offices, dedicated desks, phone booths and conference rooms. In 2022, Common Desk said it was expanding the space by 28,000 square feet, bringing it to the current size.

“(Industrious’) unparalleled expertise in delivering quality, hospitality-driven workspaces complements our vision of creating a world-class ecosystem where entrepreneurs, corporations, and academia converge to drive innovation forward,” Ken Jett, president of Rice Real Estate, said in a statement.

Natalie Levine, senior manager of real estate at Industrious, says her company will work with Rice Real Estate “to continue to position the Ion as an invaluable contributor to the growth of Houston’s innovation community.”

Dallas-based commercial real estate services company CBRE said Jan. 14 that it had agreed to acquire Industrious in a deal valued at $400 million.

The Ion is Industrious’ second location in Houston. The company’s other local coworking space is at 1301 McKinney St.

Office tenants at the Ion include Occidental Petroleum, Fathom Fund, Activate, Carbon Clean, Microsoft and Chevron Technology Ventures.

Texas ranks among the 5 best states to start a business in 2025

Best for Biz

As one of the largest states in the U.S., it's no surprise Texas is big on business and entrepreneurship. Now the state is earning new praise among WalletHub's 2025 list of "Best & Worst States to Start a Business."

The Lone Star State claimed the No. 4 spot in the report's rankings, proving that Texas is in a much better business shape than it was last year when it earned No. 8 in WalletHub's annual report.

The study compared all 50 states across 25 metrics to determine the best places to start, grow, and find success with a new business. Factors that were considered include the number of startups per capita, job growth rates, financing accessibility measures, labor costs and corporate tax rates.

The three states to outperform Texas in the 2025 report are Florida (No. 1), Georgia (No. 2), and Utah (No. 3). Idaho rounded out the top five.

Across the study's three main categories, Texas performed the best in the "business environment" category, earning No. 1 nationally. This section compares the states based on five-year business survival rates, average business revenues growth and more.

Texas ranked No. 12 in the nationwide comparison of "access to resources" – which covers working age population growth, venture investment amounts per capita and other means – and earned a fair No. 34 in the report's "business costs" ranking.

But Texas can still do better with its business friendliness to reclaim a top-three overall ranking, which the state last earned in 2023.

WalletHub analyst Chip Lupo said in the report that it is imperative for potential new business owners to establish their enterprise in a place that can maximize their ability to succeed.

"Around half of all new businesses don’t survive five years, so the idea of becoming a business owner can be daunting, especially with the current high cost of living," Lupo said. "The best states have low corporate tax rates, strong economies, an abundance of reliable workers, easy access to financing and affordable real estate. On top of that, you’ll need to make sure you start in a place with an engaged customer base, if you’re operating locally."

Houston has also proven to be at the top of the destination list for entrepreneurs who are looking for their next venture.

The top 10 best states to start a new business in 2025 are:

  • No. 1 – Florida
  • No. 2 – Georgia
  • No. 3 – Utah
  • No. 4 – Texas
  • No. 5 – Idaho
  • No. 6 – Oklahoma
  • No. 7 – Nevada
  • No. 8 – Colorado
  • No. 9 – Arizona
  • No. 10 – Kentucky
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This story originally appeared on our sister site, CultureMap.