Houston, we have a problem — and it's helping local startups have access to funding. Photo by Zview/Getty Images

A few weeks ago, Mayor of Houston Sylvester Turner and Station Houston CEO Gabriella Rowe proclaimed that Houston's up-and-coming innovation ecosystem was no longer up and coming: It had arrived. But what preceded that proclamation was years of figuring out what it was Houston could do to get to this point.

"We're the fourth largest city in the United States, and in 2015 were ranked 20th out of 25 ecosystems," Rowe says at a panel at the 2019 SXSW Interactive festival.

Following that shocking news, Rowe says the city's focus was on building tools — accelerators, incubators, education — but nowhere did anyone talk about funding. Now, years later, with plenty of accelerators, workspaces, and educational programs, Rowe says Houston now has a great pipeline of companies, but the problem is finding funding for them to tap into.

Entrepreneurs are looking for three things when it comes to finding ways to fund their companies, according to Rowe. They want it to be accessible capital — not something they have to take a class on to figure out how to get to it. They also want it to be impactful and local to where their headquarters is.

"When I think about accessible, impactful, and local, I think, well, not a lot falls into that category [in Houston]," Rowe says. "We're not doing it particularly well right now."

It's a structural problem, according to Rowe. While the city has built up its entrepreneurial climate, it hasn't yet made the same effort with investors.

"Even if we have one or two funds, we need an ecosystem that supports funding in the same way we have an ecosystem that supports entrepreneurs," she says.

Joe Milam, founder of Austin-based AngelSpan, an early stage investor relations platform, says the issue in Houston — and Austin — is that industries can be siloed. There's a huge need for an honest broker to connect the dots across the city, and that person needs to be impartial.

"You gotta care about your community first, before you care about your own agenda," Milam says. "Otherwise, you're going to flounder like Houston has, and how Austin still does."

One thing everyone agreed on during the Saturday, March 9, panel was that Houston has a lot of money, but it's been sitting on the sidelines. The mission is, in addition to bringing in venture capital firms, finding ways to engage money that's already in town.

"We have to produce tools to enable that capital that's hiding," Rowe says.

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TMC lands $3M grant to launch cancer device accelerator

cancer funding

A new business accelerator at Houston’s Texas Medical Center has received a nearly $3 million grant from the Cancer Prevention and Research Institute of Texas.

The CPRIT grant, awarded to the Texas Medical Center Foundation, will help launch the Accelerator for Cancer Medical Devices. The accelerator will support emerging innovators in developing prototypes for cancer-related medical devices and advancing them from prototype to clinical trials.

“The translation of new cancer-focused precision medical devices, often the width of a human hair, creates the opportunity to develop novel treatments for cancer patients,” the accelerator posted on the CPRIT website.

Scientist, consultant, and entrepreneur Jason Sakamoto, associate director of the TMC Center for Device Innovation, will oversee the accelerator. TMC officials say the accelerator builds on the success of TMC Innovation’s Accelerator for Cancer Therapeutics.

Each participant in the Accelerator for Cancer Medical Devices program will graduate with a device prototype, a business plan, and a “solid foundation” in preclinical and clinical strategies, TMC says. Participants will benefit from “robust support” provided by the TMC ecosystem, according to the medical center, and “will foster innovation into impactful and life-changing cancer patient solutions in Texas and beyond.”

In all, CPRIT recently awarded $27 million in grants for cancer research. That includes $18 million to attract top cancer researchers to Texas. Houston institutions received $4 million for recruitment:

  • $2 million to the University of Texas MD Anderson Cancer Center to recruit Rodrigo Romero from Memorial Sloan Kettering Cancer Center in New York City
  • $2 million to MD Anderson to recruit Eric Gardner from Weill Cornell Medicine in New York City

A $1 million grant also went to Baylor College of Medicine researcher Dr. Akiva Diamond. He is an assistant professor at the medical college and is affiliated with Baylor’s Dan L. Duncan Comprehensive Cancer Center.

Houston students develop cost-effective glove to treat Parkinson's symptoms

smart glove

Two Rice undergraduate engineering students have developed a non-invasive vibrotactile glove that aims to alleviate the symptoms of Parkinson’s disease through therapeutic vibrations.

Emmie Casey and Tomi Kuye developed the project with support from the Oshman Engineering Design Kitchen (OEDK) and guidance from its director, Maria Oden, and Rice lecturer Heather Bisesti, according to a news release from the university.

The team based the design on research from the Peter Tass Lab at Stanford University, which explored how randomized vibratory stimuli delivered to the fingertips could help rewire misfiring neurons in the brain—a key component of Parkinson’s disease.

Clinical trials from Stanford showed that coordinated reset stimulation from the vibrations helped patients regain motor control and reduced abnormal brain activity. The effects lasted even after users removed the vibrotactile gloves.

Casey and Kuye set out to replicate the breakthrough at a lower cost. Their prototype replaced the expensive motors used in previous designs with motors found in smartphones that create similar tiny vibrations. They then embedded the motors into each fingertip of a wireless glove.

“We wanted to take this breakthrough and make it accessible to people who would never be able to afford an expensive medical device,” Casey said in the release. “We set out to design a glove that delivers the same therapeutic vibrations but at a fraction of the cost.”

Rice’s design also targets the root of the neurological disruption and attempts to retrain the brain. An early prototype was given to a family friend who had an early onset of the disease. According to anecdotal data from Rice, after six months of regularly using the gloves, the user was able to walk unaided.

“We’re not claiming it’s a cure,” Kuye said in the release. “But if it can give people just a little more control, a little more freedom, that’s life-changing.”

Casey and Kuye are working to develop a commercial version of the glove priced at $250. They are taking preorders and hope to release 500 pairs of gloves this fall. They've also published an open-source instruction manual online for others who want to try to build their own glove at home. They have also formed a nonprofit and plan to use a sliding scale price model to help users manage the cost.

“This project exemplifies what we strive for at the OEDK — empowering students to translate cutting-edge research into real-world solutions,” Oden added in the release. “Emmie and Tomi have shown extraordinary initiative and empathy in developing a device that could bring meaningful relief to people living with Parkinson’s, no matter their resources.”