Grand prize winner, Traci Johannson, 3 Sons Foods; Jody Hall, H-E-B; George Johannson; Winell Herron, H-E-B; Luke and Ayden Johannson; James Harris, H-E-B. Photo courtesy of H-E-B

Five homegrown Texas businesses are enjoying Lone Star State-sized bragging rights after a big win on August 8. The entrepreneurs are the collective winners of H-E-B's sixth-annual Primo Picks Quest for Texas Best contest, which recognizes the most innovative products. Collectively, the winners earn $80,000 in prizes, and, just as important, coveted shelf space in H-E-Bs across the state.

A Houston family leads the way, joining winners from Austin; San Antonio; Woodway; and Atlanta, Texas. Houston's 3 Sons Foods won a grand prize of $25,000 and featured placement as a Texas Primo Pick for Diablo Verde Sauce, a creamy cilantro offering. The company is owned by and operated by Traci Johannson and her three young sons: George (11), Luke (14), and Ayden (16). A portion of Diablo Verde sales goes to the International Rhino Foundation to help stop the illegal poaching of rhinos, according to a release.

First place honors — and a $20,000 prize — go to Austin's Courtney Ray Goodson for her Uncle Ray's Peanut Brittle. Inspired by her great uncle Ray's 35-year-old recipe, Goodson's offerings include Bacon Pecan, Butternut, Pecan, and classic Peanut Brittle.

Hailing from Woodway, Texas, Derek Newball landed second place and $15,000 for his EVOKE collagen drink. Capitalizing on the collagen drink trend, Newball's coconut-based products are meant to benefit skin, hair, joints, and bones, and come in coconut, mandarin coconut, and pineapple coconut flavors.

To the Moon Family Foods, based in Atlanta, Texas, tied for third place (a $10,000 prize) with its To the Moon Family Foods Nutty-Carrot Spread. Creators Kay Lynn York and Joan Reece combine carrots, pecans, and "mouthwatering" spices for a spread to be used on sandwiches; meats; or even rolled in balls, coated, and fried.

Tying with To the Moon at third place (and a $10,000 prize) is San Antonio's Grain4Grain Low-Carb Flour and Mix. Owners Yoni Medhin and Matt Mechtly recycle spent grains from local microbreweries to make a low-carb, high-protein, high-fiber flour. For every pound of flour sold, Grain4Grain donates a pound to those in need.

The 2019 Quest for Texas Best competition drew more than 800 entries from nearly 140 cities and towns across the state after a call for entries in February of this year. Through two qualifying rounds, submissions were judged on taste and flavor, customer appeal, value, uniqueness, market potential, and differentiation from current products at most H-E-B stores.

"Each of these 20 competitors displayed unprecedented creativity, style, and commitment to providing outstanding, unique products for our consideration," said James Harris, director of diversity & inclusion and supplier diversity at H-E-B, in a statement. "In fact, the entries were so good that we ended up with five winners this year. We are delighted to share that diversity and ingenuity with our customers across the state."

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This story originally appeared on CultureMap.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.