Eight Houston entrepreneurs are among 16 recipients of EOY’s Gulf South Award, which recognizes leaders of high-growth companies in Central Texas, South Texas, Louisiana, and Mississippi. Photo via Getty Images

Eight Houston-area entrepreneurs have been named regional winners in Ernst & Young’s 2024 Entrepreneur Of The Year program.

The eight entrepreneurs are among 16 recipients of EOY’s Gulf South Award, which recognizes leaders of high-growth companies in Central Texas, South Texas, Louisiana, and Mississippi.

A panel of judges chose the winners based on factors such as:

  • Creation of long-term value through entrepreneurship.
  • Commitment to the purpose of their business.
  • Demonstration of growth and “substantial impact.”

“The 2024 Entrepreneur Of The Year Gulf South Award winners are exceptional business leaders fueling innovation within their industries and growth within their companies,” says Anna Horndahl, an EY partner who is co-director of EOY’s Gulf South program.

The Houston area’s Gulf South winners for 2024 are:

  • Hal Brumfield of Tachus Fiber Internet, a provider of fiber-to-the-home internet service based in The Woodlands.
  • Stuart Hinchen and Peter Jenkins of QuVa Pharma, a Sugar Land-based provider of ready-to-administer injectables.
  • Andrew Levy of Avelo Airlines, a low-cost airline based in Houston.
  • Derek Maetzold of Castle Biosciences, a Friendswood-based provider of diagnostic tests.
  • Shannon Payne of Allied Fire Protection, a Pearland-based provider of fire prevention products and services.
  • John Poindexter of JB Poindexter & Co., a Houston-based provider of automotive and manufacturing goods and services.
  • Ting Qiao of Wan Bridge, a Houston-based developer and operator of build-to-rent communities.

“These entrepreneurs are shining examples of how to lead a scaling business and also care for their employees, customers and communities,” says Travis Garms, an EY partner who is co-director of EOY’s Gulf South program.

The regional winners now qualify for consideration in the EOY national awards program. The national awards are scheduled to be presented in November.

Headed to SXSW? Here's what you need to know. Photo courtesy of SXSW

Podcast: The Houston founder's guide to navigating SXSW 2024

houston innovators podcast episode 227

Tens of thousands of people are descending upon Austin for SXSW — many of whom are ambitious startup founders. For Houston entrepreneurs, there's a lot to consider before heading down the street to Austin, and Marc Nathan can help.

The native Houstonian, who works with startups as senior director of market development at Michael Best and is based in Austin, has attended the conference for over 20 years. Every year, he assembles a comprehensive SXSW guide including round up of must-attend events, tips, and more.

He joined the Houston Innovators Podcast this week to provide his thoughts on how Houston founders can make the most of the tech-focused Interactive track — or the unofficial experiences taking place around Austin.

"You do not need a badge to enjoy and get the most out of SXSW," Nathan says, explaining that having a badge is ideal for a first timer experience. "For struggling founders who are typically broke, if you can swing the travel to get to Austin — getting here, staying here, and eating here, which are all not very cheap to start with — if you can swing that, then a badge is not that critical."

He also reminds founders that getting an invite to speak on a panel, pitch in the competition, or volunteering can score you a free or discounted badge.

On the show, Nathan shares more tips — from registering to everything you're even remotely interested in to making sure you have on your comfiest walking shoes and bring your external phone charger — on the podcast, but explains that there's really one big mistake new SXSW attendees should avoid.

"The biggest mistake I see year after year — and it's really an entrepreneur problem — but don't be too sales-y. Listen before you talk," Nathan says. "Everybody at SX is going to get it — they are going to understand the language you're speaking. It's not like explaining what your startup is to your 80-year-old grandmother. But you gotta give them a reason and a way to help you."

Headed out to SXSW? Here are a few Houston-focused events to attend.

March 9 - A $20 Trillion Challenge: Financing the Energy Transition (badge required)

A couple of Houstonians join the panel of a topic that is very prevalent in the energy capital of the world: funding of the energy transition. Juliana Garaizar joins the conversation on Saturday, March 9, at 4 pm.

March 10 - How NASA Supports Startups and Individuals to Collaborate on its Mission (badge required)

Last month, a Houston tech company launched a lunar lander in collaboration with NASA — and that's just one of countless examples of NASA's work with tech and startup companies. Join NASA for a panel discussing innovative partnerships on Sunday, March 10, at 4 pm.

March 11 - Houston House @ SXSW 2024 (badge required)

On Monday, March 11, at the LINE Hotel, the Greater Houston Partnership is hosting four panels and a happy hour. More info on the full-day event, which features over a dozen Houston-based experts, startup founders, and more, is available online.

March 12 - Women in VC Breakfast (registration required)

Houston Women in VC and Austin Women in VC are teaming up to host a breakfast with partners JP Morgan Chase and Born Global Ventures for all the female investors headed to SXSW on Tuesday, March 12, at 9 am. Request your registration online.

Learn from the mistakes of a successful Houston entrepreneur — from teamwork tips to reasons why you should network with other startups. Emilija Manevska/Getty Images

6 things this Houston entrepreneur wishes he’d known before starting his company

Guest column

Recently, I was asked what it took to build a startup in Houston. It has taken me three attempts to create a successful startup, and there were a few things that I wish I'd known right out of the gate.

Whether your goal is to exit through a sale, an IPO, or turn your team of pirates into something that looks like a company, your business model will determine how you earn revenue and profits, and you want it to be repeatable and scalable to survive. With that in mind, here are the things I've learned along the way and what I wish I had known before I started my career as an entrepreneur.

Location does matter 

Houston is great for food, sports, and massive rainfall, but it's difficult to find a large pool of talented full-stack software engineers who speak cloud. I recruited some of the best, but it was incredibly difficult to find them compared to markets like Austin, Denver, and San Francisco.

I've seen successful companies build two separate offices, one for a headquarters, and another for development, but for us, we didn't need to build a massive team, so we remained close to customers in Houston and hired a remote team in California. If you need to build a large engineering team, consider a different city or go remote.

Startups have well-defined phases 

Your startup is not a snowflake. There have been thousands upon thousands of entrepreneurs that have succeeded and failed, and a few people have studied them to understand their histories and roadmaps. I wish I learned from them before I began, instead of spending every waking hour building a product, and competing with development time for research.

Looking back, we followed the same trail taken by many other B2B startups, like: Product-market fit, sales optimization, customer success, marketing focus, and eventually scale. It's important to know which phase you are in, who you need to hire in each phase, and most importantly, how your role changes in each one.

Partner roles need to be well understood 

One of largest factors on your probability of success is your team. When choosing your partners, I would suggest using an odd number of people to break stalemates, and to always have a CEO. One person needs to be in charge of execution, I can tell you first hand that committees do not scale well when you need a high velocity of decision making.

When choosing your team, make note of Cal Newport's research on career capital, which is the rare and valuable skills that one can leverage help your startup succeed. If your friend knows how to code or understands databases, ask yourself if he/she is the best in their class, because these are skills that you can hire for or contract out. The traits that accelerated our success were a unique blend of domain expertise, petroleum-specific software knowledge, deep business development expertise, and strong sense of diligence and commitment, which is what became our culture.

Finally, you and your partners need to know what needs to be done, and how you can individually contribute. Your contributions will change in each phase, and each of you need to understand how your roles will change, and be prepared to adapt quickly. If one of your partners writes the first line of code, doesn't mean they'll be the CTO when you have 150 people, the person that makes the first sale may not be the CRO when you have a 30 person salesforce. For those with a large ego, it's one of the hardest things to accept, but must be acknowledged in order for a team to succeed.

Your idea is probably wrong, but that is okay 

We used agile and lean philosophies to build our organization, and our approach was centered around what Steve Blank calls "customer discovery," the understanding of how to find a product-market fit. These methods subscribe to the hypothesis that successful startups are defined by their team's execution, and not the idea alone. We ditched our first idea after two weeks and pivoted to a new one, and we learned from our customers very quickly and created over 115 prototypes in 10 months before making the first sale. Each group of customers saw a different prototype, and each beta-tester used a different design, a different stack, a different user experience. We had to learn quickly. Agile and lean processes helped us iterate quickly and discover what our customers needed, but a highly skilled team was needed to figure out how to use the processes correctly.

Connect with others who have made it

Success is a multi-variate formula that compounds every good and bad decision unequally. If you don't know the answer to a key decision, your team can help, if they don't know, then find another team that has navigated your trail to provide advice.

In Houston, there are not many teams who have been through this, we leaned on help from the Austin network. I'm a big believer in helping the community of entrepreneurs, and I am more than happy to throw down the rope to help others in their ascent.

Money is your oxygen

Lastly, learning to hold your breath isn't a long-term strategy for deep sea dives. You'll need to know how many months of oxygen you have in your bank account at all times. There is no magic number of months for runway, but I can tell you from experience that three months is too little for oil and gas tech startups, especially when OilCo's take three to six months to sign and pay your invoices.

I can't emphasize how difficult starting a company can be. By reflecting on the points I mentioned here, I believe that I would have avoided some pitfalls, and maybe even made it a little farther in the journey.

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James Ruiz is the founder of Houston-based Q Engineering, a data driven solutions company for E&P professionals.

Entrepreneurs' Organization had seven of its members give TED-style talks on April 25. Ammar Selo

Overheard: 9 powerful quotes from TED-style talks by Houston entrepreneurs

Eavesdropping in Houston

Moving the needle on something — whether it's changing the world or growing your business — hearing how others accomplished their own goals can be a beacon of hope and guidance for others.

The local Entrepreneurs' Organization chapter, EO Houston, hosted a series of seven TED Talk-style talks by members of the organization. These seven entrepreneurs discussed everything from being an introvert in a world of extroverts to the biggest security threat to American citizens: obesity. EO Talks took place at a breakfast event on April 25 at Houston Baptist University. If you missed the event, check out these overheard quotes from the day of discussions.

“When you get people involved in your organization, your job (as CEO) is alignment. Keep your team aligned with the strategic objectives of your company.”

— Paul Sarvadi, chairman, CEO and co-founder of Insperity, in his talk, "Take Care of Your People: An Entrepreneur's Journey." Connectivity is key, says Sarvadi.

“Taking care of your people is not rocket science. In fact, rocket science would be easier. It involves math and science — it works the same every day. But as soon as you put people in the mix, what worked yesterday might not work today.”

— Sarvadi continued in his talk about the importance of human resources in the the work place.

“What if everyone in the world knew what they stood for — imagine what that world would look like. We would know how we fit. We would be the best versions of ourselves. And, the world would be the best version of itself.”

— Winnie Hart, founder of TwinEngine in her talk, "What Do You Stand For?" Hart discussed finding one's identity and motivators — both in business and in life.

“Everywhere we look introverts are living in an extroverted world. It’s natural if you’re an introvert, like me, to feel a little insecure or that you feel the need to compete with your extraverted friends.”

— Darlene Gagnon, CEO and co-founder of Kinnect Global Management Services in her talk, "The Introverted Entrepreneur Competing in an Extroverted World." Gagnon says that introverts on track to be the most successful entrepreneurs with their execution skills, detail oriented nature, and ability to tune out the noise.

“It is the men in our lives that need to take action. Gentlemen, stand with us. Help us create a better presence so that we can sustain a future.”

— Shoshi Kaganovsky, CEO and founder of SensoLeak Global, in her talk, "Women Entrepreneurs—To Be..Or..To Be The Best." Kaganovsky compared how people say, "behind every great man is a woman," to how female leaders also need the support from the other gender.

“Entrepreneurship is an endless circle of reinventing yourself, being able to change, and keeping a positive attitude while doing so.”

— Kaganovsky continued in her talk as advice to the room of entrepreneurs.

“We can escape this crushing threat we call obesity. How are you going to make your escape?”

— Dr. Joe Galati, liver disease expert, radio host and author in his talk, "America's #1 National Security Threat." Galati argued that it's not Russia or North Korea that pose a major threat to the United States — it's our own health issues caused by obesity.

“We’ve all heard of the term ‘side hustle.' Maybe my dad invented the ‘side hustle.’”

— Chris Hotze, CEO and founder of Crescere Capital, in his talk, "Understanding the Power of Recurring Revenue." Hotze tells the story of how his father created a residential real estate side business out of necessity, and how that entrepreneurialism affected his own business career.

“As entrepreneurs, as long as we see control, we visualize an opportunity far greater than we see the risk.”

— Ali Nasser, CEO of AltruVista in his talk, "The Entrepreneur's Opportunity Cost," Nasser explains how entrepreneurs are hesitant to put money in the stock market, yet dive into ownership and risks for their own businesses.

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Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”

Aegis Aerospace appoints Houston space leader as new president

moving up

Houston-based Aegis Aerospace's current chief strategy officer, Matt Ondler, will take on the additional role of president on Jan. 1. Ondler will succeed Bill Hollister, who is retiring.

“Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers,” Stephanie Murphy, CEO of Aegis Aerospace, said in a news release.

Hollister guided Aegis Aerospace through expansion and innovation in his three years as president, and will continue to serve in the role of chief technology officer (CTO) for six months and focus on the company's technical and intellectual property frameworks.

"Bill has played an instrumental role in shaping the success and growth of our company, and his contributions leave an indelible mark on both our culture and our achievements," Murphy said in a news release.

Ondler has a background in space hardware development and strategic leadership in government and commercial sectors. Ondler founded subsea robots and software company Houston Mechatronics, Inc., now known as Nauticus Robotics, and also served as president, CTO and CSO during a five-year tenure at Axiom Space. He held various roles in his 25 years at NASA and was also named to the Texas Aerospace Research and Space Economy Consortium Executive Committee last year.

"I am confident that with Matt at the helm as president and Bill supporting us as CTO, we will continue to build on our strong foundation and further elevate our impact in the space industry," Murphy said in a news release. "Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers."

Rice University launches new center to study roots of Alzheimer’s and Parkinson’s

neuro research

Rice University launched its new Amyloid Mechanism and Disease Center last month, which aims to uncover the molecular origins of Alzheimer’s, Parkinson’s and other amyloid-related diseases.

The center will bring together Rice faculty in chemistry, biophysics, cell biology and biochemistry to study how protein aggregates called amyloids form, spread and harm brain cells. It will serve as the neuroscience branch of the Rice Brain Institute, which was also recently established.

The team will work to ultimately increase its understanding of amyloid processes and will collaborate with the Texas Medical Center to turn lab discoveries into real progress for patients. It will hold its launch event on Jan. 21, 2026, and hopes to eventually be a launchpad for future external research funding.

The new hub will be led by Pernilla Wittung-Stafshed, a Rice biophysicist and the Charles W. Duncan Jr.-Welch Chair in Chemistry.

“To make a real difference, we have to go all the way and find a cure,” Wittung-Stafshede said in a news release. “At Rice, with the Amyloid Mechanism and Disease Center as a catalyst, we have the people and ideas to open new doors toward solutions.”

Wittung-Stafshede, who was recruited to Rice through a Cancer Prevention and Research Institute of Texas grant this summer, has led pioneering work on how metal-binding proteins impact neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Her most recent study, published in Advanced Science, suggests a new way of understanding how amyloids may harm cells and consume the brain’s energy molecule, ATP.

According to Alzheimer’s Disease International, neurodegenerative disease cases could reach around 78 million by 2030 and 139 million by 2050. Wittung-Stafshede’s father died of dementia several years ago.

“This is close to my heart,” Wittung-Stafshede added in the news release. “Neurodegenerative diseases such as dementia, Alzheimer’s and Parkinson’s are on the rise as people live longer, and age is the largest risk factor. It affects everyone.”