This Houston company has the key to a more exact searching process when it comes to finding a new home to buy. Courtesy photo

For most consumers, the home buying process includes a very specific online search. People specify their neighborhood requirements, the number of bedrooms or bathrooms, backyard size, and more — yet still, the search results in a staggering amount of homes. It's way more than anyone can reasonably look at.

That's where Martin Kay and Entera Technology, the company he founded and is CEO of, come in. Kay, a 20-year veteran of the tech sector, who's bought multiple homes as rental properties, realized the way to solve the problem of that kind of search engine overload was through machine learning. He now works with some of the largest home-buying companies in the world, helping them find properties that match the specifications they have to attract the clients they want.

"All residential real estate is a consumer product," he says. "Ultimately, the people who are going to live in that home care most about, is it a nice home with a big backyard neat good schools, is it safe? The [home buying] companies are trying to figure out what do the end consumers really care about so we can give them exactly what they need?"

To do so, Entera collects data — lots and lots of it. Kay and his team have taught their software programs what a chef's kitchen is, for example. They did so by compiling tens of thousands of photos of kitchens and telling the software, "This is a kitchen." Then, they taught it to recognize what makes a chef's kitchen — a larger size, more than one sink, high-end appliances. They used the same techniques in identifying things like millennial-friendly neighborhoods or neighborhoods that were up-and-coming on the real estate scene. They draw from listings available with the Houston Association of Realtors and beyond, a vast array of tens of thousands of homes.

Officially launched in 2017, Entera blends its data collection and analysis with on-the-ground service. After Entera's proprietary software collects what it thinks home-buying companies want, members of Entera's service team go out to look at the homes.

"We're a little bit like Netflix," he says. "They go out and get content from everyone, and they begin to watch your behavior. So, Netflix has 2,000 profiles and you probably fit five or six of those. We have almost 100 profiles and what we do is say, we're going to understand what you want, watch your behavior and instead of giving you 40,000 properties on a big map, we actually match you based on your preferences, to the five or six houses that are best for you."

While Entera has been working with larger home-buying companies — like firms that buy tens of thousands of homes every year — Kay says they have begun working with smaller entities, and he figures within the next few years, Entera will be using the same data collection and machine learning to work with individual home buyers.

Based in Houston, Entera has operations in New York and San Francisco as well. The company has 17 full-time employees, along with approximately 100 contractors in its markets. And while Kay understand a human touch is needed in business, he loves that he can use a data model to present unbiased opinions to his clients.

"[Real estate] actually affects people's lives meaningfully," Kay says. "Real estate data — where you live, what your neighborhood is, how you make that choice — …this data matters to people in a way they can tangibly touch and understand and feel. We can help people make what are big, complex choices that are often highly ambiguous. I love it because it matters. You can measure how it matters immediately."

Data-driven tech

Courtesy of Entera

Entera focuses on collecting data and analysis and pairs it with on-the-ground service. After Entera's proprietary software collects what it thinks home-buying companies want, members of Entera's service team go out to look at the homes.

A growing digital home sales platform has moved into town. Courtesy photo

Digital home buying and selling tool expands to Houston market

Real estate tech

A Phoenix-based real estate company has expanded to the Houston market and opened a new office in town.

First launched in 2015, Offerpad is a tech-enabled home buying and selling solution. As of October, Offerpad had expanded to 534 cities with access to an estimated 6.7 million home-owning households.

The company is what's known as an iBuyer — a type of investor that uses automated valuation models, or AVMs, and other technology to quickly turn around offers on homes to sellers and then resell them to home buyers. The process tends to be quicker and higher tech than the normal home selling and buying process.

Offerpad previously had expanded into Dallas before launching in Houston on January 15. It's the first expansion in 2019 — a year that's poised to be full of growth for the company, the press release says.

"The company has a very concentrated vision to bring our real estate solutions to millions more people this year," Trent Capps, Offerpad's regional market director focused on Texas, says in the release. "Our start in Texas, with Dallas-Fort Worth, has far and away exceeded our expectations and we anticipate the same for our other Texas markets. In Houston, we began receiving home offer requests weeks ago, so we foresee huge success there, as well as in San Antonio later in the quarter."

The new local office is located in The Woodlands and serves 86 cities within the Houston area including Bellaire, Pearland, Sugar Land, Seabrook, and Friendswood. San Antonio is the next Texas market Offerpad is headed for.

"Dallas, Houston, and San Antonio are all cities we've had intentions of offering our service in," Founder and CEO Brian Bair says in the release. "I'm confident that Texans are going to value the solutions we've developed to the once complicated and stressful process of selling a home."

Graphic courtesy of Offerpad

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Autonomous truck company with Houston routes goes public

on a roll

Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

“We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

“We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.

Rice University scientists invent new algorithm to fight Alzheimer's

A Seismic Breakthrough

A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

“As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

“We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

“We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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This article originally appeared on CultureMap.com.

5 incubators and accelerators fueling the growth of Houston startups

meet the finalists

Houston is home to numerous accelerators and incubators that support founders in pushing their innovative startups and technologies forward.

As part of our 2025 Houston Innovation Awards, the new Incubator/Accelerator of the Year category honors a local incubator or accelerator that is championing and fueling the growth of Houston startups.

Five incubators and accelerators have been named finalists for the 2025 award. They support startups ranging from hard-tech companies to digital health startups.

Read more about these organizations below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled.

Get your tickets now on sale for this exclusive event celebrating Houston Innovation.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced last year, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its second Houston cohort this summer.

This year, the incubator grew to include its largest number of concurrent supported fellows, with 88 companies currently being supported nationally. In total, Activate has supported 296 fellows who have created 236 companies. Those companies have raised over $4 billion in follow-on funding, according to Activate. In Houston, it has supported several Innovation Awards finalists, including Solidec, Bairitone Health and Deep Anchor Solutions. It is led locally by Houston Managing Director Jeremy Pitts.

EnergyTech Nexus

Cleantech startup hub EnergyTech Nexus' mission is to accelerate the energy transition by connecting founders, investors and industrial stakeholders and helping to develop transformative companies, known as "thunderlizards."

The hub was founded in 2023 by CEO Jason Ethier, Juliana Garaizar and Nada Ahmed. It has supported startups including Capwell Services, Resollant, Syzygy Plasmonics, Hertha Metals, EarthEn Energy and Solidec—many of which are current or past Innovation Awards finalists. This year Energy Tech Nexus launched its COPILOT Accelerator, powered by Wells Fargo Innovation Incubator (IN²) at the National Renewable Energy Laboratory (NREL). COPILOT partners with Browning the Green Space, a nonprofit that promotes diversity, equity and inclusion (DEI) in the clean energy and climatech sectors. Energy Tech Nexus also launched its Liftoff fundraising program, its Investor Program, and a "strategic ecosystem partnership" with Greentown Labs.

Greentown Labs

Climatetech incubator Greentown Labs offers its community resources and a network to climate and energy innovation startups looking to grow. The collaborative community offers members state-of-the-art prototyping labs, business resources and access to investors and corporate partners. The co-located incubator was first launched in Boston in 2011 before opening in Houston in 2021.

Greentown has seen major changes and activity this year. In February, Greentown announced Georgina Campbell Flatter as its new CEO, along with a new Board of Directors. In July, it announced Lawson Gow as its Head of Houston, a "dedicated role to champion the success of Greentown Houston’s startups and lead Greentown’s next chapter of impact in the region," according to Greentown. It has since announced numerous new partnerships, including those with Energy Tech Nexus, Los Angeles-based software development firm Nominal, to launch the new Industrial Center of Excellence; and Houston-based Shoreless, to launch an AI lab onsite. Greentown Houston has supported 175 startups since its launch in 2021, with 45 joining in the last two years. Those startups include the likes of Hertha Metals, RepAir Carbon, Solidec, Eclipse Energy (formerly GoldH2) and many others.

Healthtech Accelerator (TMCi)

The Healthtech Accelerator, formerly TMCx, focuses on clinical partnerships to improve healthcare delivery and outcomes. Emerging digital health and medical device startups that join the accelerator are connected with a network of TMC hospitals and seasoned advisors that will prepare them for clinical validation, funding and deployment.

The Healthtech Accelerator is part of Texas Medical Center Innovation, which also offers the TMCi Accelerator for Cancer Therapeutics. The Healthtech Accelerator named its 19th, and latest, cohort of 11 companies last month.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with 24,000-plus members spanning 69 countries, making it one of the world’s largest communities for accelerating entrepreneurial solutions toward the United Nations' Sustainable Development Goals (SDGs).

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.