Workers in the Lone Star State put in more hours and take less vacation time than most of America. Photo by gguy44/Getty Images

Texans don't just work hard, they work harder than almost anyone else in the nation, according to a new study.

Just in time for Labor Day, WalletHub has revealed the hardest-working states for 2019, and Texas lands at No. 4, meaning only three states — North Dakota, Alaska, and South Dakota — work harder. To determine the ranking, the personal finance site reviewed a host of factors, from average workweek, commute time, and leisure time to employment rates and the share of workers with multiple jobs.

In Texas, where 96 percent of the labor force has a job, workers stay on the clock an average of 40 hours a week. While that might seem pretty standard, somehow, that makes us the state with the fourth-longest workweek.

And those hardworking Texans could use a break. Surprisingly, 29 percent of the state's workers don't use all of their vacation time. One contributing factor could be the state's high percentage of engaged workers (35 percent), described in the study as "involved in, enthusiastic about, and committed to their work and workplace."

As we know, work doesn't just start and end at your desk. WalletHub also measured workers' commute times, volunteer hours, and leisure time, which it categorized as indirect work factors.

In Texas, workers regularly travel about 26 minutes one way for their jobs, and despite their long workweeks, they make time to volunteer for 27 hours each year on average. In regards to work-life balance, Texans set aside almost six hours a day for leisure time. That may sound ample, but workers in 19 other states spend even more time relaxing.

This isn't the only recent study to call attention to how much time Texans spend on the clock.

A recent report from mobile technology company Kisi named Houston, where workers clock 43.7 hours a week, the second most overworked city in the U.S., second only to Washington, D.C. Austin also shot to the top of the list, with workers laboring 43.5 hours a week, followed by San Antonio (43.1 hours) and Dallas (42.9 hours).

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This article originally ran on CultureMap.

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Axiom Space-tested cancer drug advances to clinical trials

mission critical

A cancer-fighting drug tested aboard several Axiom Space missions is moving forward to clinical trials.

Rebecsinib, which targets a cancer cloning and immune evasion gene, ADAR1, has received FDA approval to enter clinical trials under active Investigational New Drug (IND) status, according to a news release. The drug was tested aboard Axiom Mission 2 (Ax-2) and Axiom Mission 3 (Ax-3). It was developed by Aspera Biomedicine, led by Dr. Catriona Jamieson, director of the UC San Diego Sanford Stem Cell Institute (SSCI).

The San Diego-based Aspera team and Houston-based Axiom partnered to allow Rebecsinib to be tested in microgravity. Tumors have been shown to grow more rapidly in microgravity and even mimic how aggressive cancers can develop in patients.

“In terms of tumor growth, we see a doubling in growth of these little mini-tumors in just 10 days,” Jamieson explained in the release.

Rebecsinib took part in the patient-derived tumor organoid testing aboard the International Space Station. Similar testing is planned to continue on Axiom Station, the company's commercial space station that's currently under development.

Additionally, the drug will be tested aboard Ax-4 under its active IND status, which was targeted to launch June 25.

“We anticipate that this monumental mission will inform the expanded development of the first ADAR1 inhibitory cancer stem cell targeting drug for a broad array of cancers," Jamieson added.

According to Axiom, the milestone represents the potential for commercial space collaborations.

“We’re proud to work with Aspera Biomedicines and the UC San Diego Sanford Stem Cell Institute, as together we have achieved a historic milestone, and we’re even more excited for what’s to come,” Tejpaul Bhatia, the new CEO of Axiom Space, said in the release. “This is how we crack the code of the space economy – uniting public and private partners to turn microgravity into a launchpad for breakthroughs.”