University of Houston names new leaders within innovation, tech

appointments made

Haleh Ardebili (left) has been appointed as assistant vice president of Entrepreneurship and Startup Ecosystem, and Michael Harold as assistant vice president for Intellectual Property and Industrial Engagements at the University of Houston. Photo via UH

Two professors have assumed new leadership roles in the University of Houston’s Office of Technology, Transfer, and Innovation.

Haleh Ardebili, the Kamel Salama Endowed Professor of Mechanical Engineering, has been named assistant vice president of entrepreneurship and startup ecosystem. Michael Harold, Cullen Engineering Professor of Chemical and Biomolecular Engineering, has been named assistant vice president for intellectual property and industrial engagements.

Ardebili and Harold “are both tested leaders in their respective areas —they are already contributing to our rich academic environment with their knowledge, expertise and commitment to innovation,” says Ramanan Krishnamoorti, vice president for energy and innovation at UH, in a statement. “Having them helm our growing team will help UH continue its culture of innovation and contribution to society.”

In her new role, Ardebili will oversee entrepreneurship and startup efforts at UH. She will direct the startup and entrepreneurship staff within the Office of Technology, Transfer, and Innovation (OTTI).

Ardebili, who joined the university in 2004, previously was director of the Cullen College of Engineering’s Innovation and Entrepreneurship Initiative.

In his new role, Harold will lead the university’s technology transfer activities. He will direct the OTTI licensing and IP management staff.

Harold worked at DuPont in various technical and managerial positions between 1993 and 2000. He joined UH in 2000 as chair of the Department of Chemical Engineering. He served as chair until 2008 and again from 2013 to 2020.

“Both positions will play integral roles in increasing faculty engagement, facilitating innovations from research labs to market, and enhancing collaboration with internal and external stakeholders. These appointments underscore UH’s commitment to driving innovation, economic development, and industry partnerships,” the university says in the release.

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This week's roundup of Houston innovators includes Don Frieden of P97, Haleh Ardebili of the University of Houston, and Babur Ozden of Aquanta Vision. Photos courtesy

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from fintech to energy — recently making headlines in Houston innovation.

Don Frieden, president and CEO of P97

Don Frieden, president and CEO of P97, shares how he plans to streamline day-to-day transactions on the Houston Innovators Podcast. Photo courtesy of P97

Before Don Frieden started his company, gas stations hadn't innovated their payment technology since 1997. He knew that needed to change.

P97, founded in 2012, exists to use innovative technologies to simplify and energize daily journeys, Frieden explains on the Houston Innovators Podcast.

"We think about daily journeys from the time we leave home in the morning and when we get back at the end of the day — whether it's tolling, parking, buying fuel, fast food restaurants, it's all a part of your daily journeys, and our goal is to make things a little bit simpler each day," Frieden says on the show. Read more.

Haleh Ardebili, professor of Mechanical Engineering at University of Houston

Haleh Ardebili is the the Bill D. Cook Professor of Mechanical Engineering at UH. Photo courtesy

A new prototype out of the University of Houston feels more like science fiction than reality.

"As a big science fiction fan, I could envision a ‘science-fiction-esque future’ where our clothes are smart, interactive and powered,” according to a statement Haleh Ardebili, who last month published a paper on a new stretchable fabric-based lithium-ion battery in the Extreme Mechanics Letters.

“It seemed a natural next step to create and integrate stretchable batteries with stretchable devices and clothing," she said. "Imagine folding or bending or stretching your laptop or phone in your pocket. Or using interactive sensors embedded in our clothes that monitor our health.”

The battery uses conductive silver fabric as a platform and current collector, which stretches (or mechanically deforms) while allowing movement for electrons and ions. Traditional lithium batteries are quite rigid and use a liquid electrolyte, which are flammable and have potential risks of exploding. Read more.

Babur Ozden, founder of Aquanta Vision

Babur Ozden is the founder of Aquanta Vision. Photo via LinkedIn

Aquanta Vision Technologies, a Houston-based climate-tech startup, was selected to participate in the scale-up phase of Chevron Studio, a Houston program that matches entrepreneurs with technologies to turn them into businesses. Aquanta's computer vision software completely automates the identification of methane in optical gas imaging, or OGI. The technology originated from Colorado State University and CSU STRATA Technology Transfer.

Babur Ozden, a tech startup entrepreneur, along with Marcus Martinez, the lead inventor and Dan Zimmerle, co-inventor and director of METEC at CSU Energy Institute, came up with the technology to identify the presence and motion of methane in live video streams. Currently, this process of identifying methane requires a human camera operator to interpret the images. This can often be unreliable in the collection of emissions data.

Aquanta’s technology requires no human intervention and is universally compatible with all OGI cameras. Currently, only about 10 percent of the 20.5 million surveys done worldwide use this type of technology as it is extremely expensive to produce. Ozden said he hopes Aquanta will change that model.

“What we are doing — we are democratizing this feature, this capability, independent of the camera make and model,” Ozden says. Read more.

University of Houston Professor Haleh Ardebili (right) and Navid Khiabani, a graduate research assistant, are creating bendable batteries. Photo via UH.edu

Houston researchers develop new battery prototype to impact wearable technology

flexible innovation

A new breakthrough prototype out of the University of Houston was inspired by science fiction.

The technology is only a prototype now, but Ardebili, who's the Bill D. Cook Professor of Mechanical Engineering at UH, and the paper's first author Bahar Moradi Ghadi, a former doctoral student, think the battery could have many applications, including in smart space suits, consumer electronics and implantable biosensors.

While it's just a prototype now, the technology has a lot of potential in the wearable tech space. Photo via UH.edu

The team's focus now is to ensure the battery is "as safe as possible" before it becomes available on the market.

“Commercial viability depends on many factors such as scaling up the manufacturability of the product, cost and other factors,” Ardebili said. “We are working toward those considerations and goals as we optimize and enhance our stretchable battery.”

Ardebili first conceptualized the product several years ago and has since earned several key wards and grants to support the design, including a five-year National Science Foundation CAREER Award in 2013, a New Investigator Award from the NASA Texas Space Center Grant Consortium in 2014 and an award from the US Army Research Lab in 2017.

A number of Houston-based organizations are working to create innovative batteries.

Earlier this summer, TexPower EV Technologies Inc. opened a 6,000-square-foot laboratory and three-ton-per-year pilot production line in Northwest Houston to help the University of Texas-born company to further commercialize its cobalt-free lithium-ion cathode, which can be used in electric vehicles.

Another Houston-based company Zeta Energy has also developed proprietary sulfur-based cathodes and lithium metal anodes that have shown to have higher capacity and density and better safety profiles than lithium sulfur batteries. The company landed a $4 million grant from the U.S. Department of Energy's ARPA-E Electric Vehicles for American Low-Carbon Living, or EVs4ALL, program, in January.

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

2024 Google search volume for terms related to investing
Number of investors
Number of businesses receiving investments in 2024
Total amount of capital invested in businesses in 2024
Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

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