Guide App, a Houston startup, is looking to help its users tap into social media better. Photo via Getty Images

Just look at any smartphone on the market and it becomes evident just how pervasive mobile apps have become, especially social media apps.

As the social networking sphere has revolutionized communication, technology has spawned multitudinous variants in the most organic way. That kind of technological momentum lends itself to why platforms like Guide App have a chance to be the next big thing in the space.

The company's CEO and co-founder, Tim Salau, tells InnovationMap that Guide is a social learning and development platform that aims to revolutionize learning experiences for creators, leaders, and organizations.

“Guide is a social learning platform for creators who are freelancers and work in the entertainment and media industry,” says Salau, Houston native and University of Texas graduate. “And they can use Guide to create and learn production skills. We pivoted in late 2019 as the pandemic hit, and we realized that Guide could be used as a B2B platform and solution for businesses to onboard and train their remote workers.

“So that's really what makes us money, and we really decided to build it because we saw that there was a huge gap in the business space of a bite-sized training platform and solution, and to do what TikTok and Reels was doing in the consumer space, but for professionals with security and privacy in mind for organizations,” he says.

With the pivot, businesses can now use Guide as a platform to onboard and train new hires for their respective companies.

“Ideally, it would be pretty much anyone within the marketing department, the product management division, or even engineers within their organizations who are creators in the sense of migrating to creative work in their own different disciplines,” says Salau. “And they could use Guide to potentially maybe create a video that's 90 seconds or less on everything a new hire needs to know within the first 90 days in the product management role or in the marketing role.”

Tapping into trends

Salau explains how he's got his ear to the ground when it comes to trends within media.

“With the way that things are moving in the entertainment and media industry and what's been happening with these strikes, I see the short-form content becoming even more important because people are not necessarily attending movie theaters at a high engagement rate,” says Salau. “Then there are multiple streaming platforms have so many gates and paywalls up, a lot of people aren't necessarily using all of these streaming platforms and seeing all of the long-form content out."

“I'm starting to see that in the next three to five years, macro content will become more important, and instead of the streaming era that we've seen in the last few years or in the last decade or so led by Netflix, I'm going to use our mock theory, we're going to start seeing a beaming era in which we're going to start seeing content being pushed to creators and consumers, that is literally tailored to what they want.”

According to Salau, platforms such as Instagram and TikTok push content based on their respective algorithms that followers don’t necessarily want to see, and that takes time away from the content they need, when they need it.

“Looking forward, it’s clear that in the sense of taking away all of the distractions that we see on these platforms, at Guide, we want to push content as it comes from the creators,” says Salau. “And for us, that focus will be on microcontent, which is content that’s 90 seconds or less.”

Data shows that the best micro content is video content that clocks in around 15 seconds.

“Content that goes up to 30 seconds is probably even cutting it a little bit too long, but the content that really goes a lot, and goes really viral on those platforms is 15 seconds,” says Salau. “And now that TikTok is becoming a more long-form entertainment platform, you're starting to see them kind of strip away from what really got them popular and buzzworthy.”

Monitoring monetization

Popularity aside, one of the major tenets of content creation is monetization.

“Getting to the point where creators will be able to monetize their content is our goal at Guide,” says Salau. “We have to build up towards that goal, but that’s the intent. We intend on having them be able to create profiles where they can actually list their merch. They can post about merch in their videos, and more importantly, get to a point where people can actually buy the entertaining content that they have.”

Once Guide reaches monetization, creators will be able to list content at the price they want it and have associated merchandise of their brand. This is a huge difference from how TikTok and Instagram and other consumer video platforms get creators paid.

“We see that it's better to actually go the other route and actually allow creators to monetize their own brand, which is what every creator often really wants,” says Salau. “That’s ideal because when a creator brings consumer brands into the picture, they have to play to what they want from an advertisement and dollars type of standpoint. So, we don't want to actually get into that world. We want to really keep everything creator oriented.”

Curating a culture of creators

At this point, Guide has about 150 creators, because they’ve been very selective with their icon program.

“We don’t believe that everyone’s a creator,” says Salau. “Because if everyone is a creator, then no one is a creator.

“And we kind of see this with a lot of the creator platforms out there. Just because anyone can create content with a smartphone doesn't mean it's content that's edifying or beneficial that people are actually enriching and learning from. So, we're really big on learning, because we see ourselves in that space.”

As Salau and team look forward with Guide, they plan on continuing to address the learning and talent development gap for remote and mobile teams. They’ll also remain focused on being the kind of platform where creators can talk about the behind-the-scenes and the process of how to make music or how to approach acting, or how to think about set production when on a set.

“With Instagram and TikTok, it’s really much more about fun and virality, and doing something that gets a reaction, versus helping people learn,” says Salau. “So, with us, the feedback we've received is, ‘I get it,’ and ‘I'm interested.’ And I want to continue learning and growing with y'all. Thank you.”

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UH lands $1.2M NIH grant to fight superbugs using AI, quantum sensing

drug defense

The fight against antibiotic-resistant bacteria like MRSA is getting science fiction-like upgrades at the University of Houston thanks to a new four-year, $1.26 million grant from the National Institutes of Health.

The university says the recent funding brings total federal support up to $3.5 million for 11 years for the project, which uses AI and quantum-sensing technology to better understand how bacterial proteins develop resistance to drugs.

Any medical professional will tell you that one of the worst things that can happen is almost killing an infection. Bacteria that survive attacks from conventional antibiotic treatments emerge tougher, more resistant and more aggressive than before–making them much harder to treat. A good example is the superbug methicillin-resistant Staphylococcus aureus (MRSA).

UH chemistry professors Yuhong Wang and Shoujun Xu are working on this issue. They know full well that fighting superbugs requires new technology and new approaches, which is what they aim to pioneer with their new grant.

“Drug-resistant bacterial infections such as MRSA are becoming harder to treat, creating an urgent need for faster ways to understand how antibiotics and other small molecules interact with bacterial proteins,” Wang said in a news release.

Wang and Xu’s work centers around GTP, a cellular fuel that can cause tiny changes to a cell's structure when it mutates. Sometimes, those shape changes make it easier for drugs to breach the wall and attack the cells.

The UH scientists are employing AlphaFold, an AI-powered tool that can scan large molecular libraries in seconds. From these models, they can see promising drug combinations for future testing.

Once identified, the team uses their invention, super-resolution force spectroscopy, to monitor the cells. Tiny magnetic beads are attached to genetic material, then magnified to see how strong that material is when pulled. They can measure this incredible microscopic process through an atomic magnetometer, typically used in quantum physics. Combined, all these tools allow a high-definition look at how each molecule might respond to new chemical approaches.

“We're the only chemists in the world that use an atomic magnetometer for biological research,” Xu said. “It's a technique developed by physicists, and there is usually a gap between techniques developed by physicists and biological applications. Yuhong and I have been bridging that gap together for the past 10 years.”

Eventually, Wang and Xu hope to develop powerful software that can be used by drug manufacturers to model cellular responses. With enough predictive data, the software could even get ahead of superbugs’ own mutation, allowing drugs to be developed before new strains arrive.

"We want an algorithm where you input a protein sequence, score the mutation hotspots, and develop new inhibitors before a drug-resistant species even emerges," Wang added.

SpaceX to get more than 700 acres of Texas wildlife refuge in land swap

Space News

A federal judge on Monday, September 21, refused to block the Trump administration from giving SpaceX more than 700 acres of wildlife refuge as part of a land swap in Texas, while environmental groups vowed to continue their legal challenge.

U.S. District Judge Fernando Rodriguez Jr. declined the plaintiffs' request for a preliminary injunction to prevent the parcel exchange, saying they failed to prove it would worsen ecological risks to a Gulf Coast region already transformed by billionaire Elon Musk’s rocket operations.

In June, the U.S. Fish and Wildlife Service approved moving forward with the deal with SpaceX, which would surrender 683 acres the company owns in exchange for the federal land in the Lower Rio Grande Valley National Wildlife Refuge. The 103,000-acre refuge spans four counties along the Texas border and is home to animal habitats and historical landmarks.

Maps show the land SpaceX would acquire would be closer to the company's launchpad near the U.S.-Mexico border.

The swap amounts to a gift of public lands to SpaceX, “clearing the way for bulldozers to tear into this wildlife refuge as soon as next week and turn a public treasure into a private payday,” said Laiken Jordahl, a spokesperson with the Center for Biological Diversity, which filed the lawsuit alongside other opponents including tribal groups. Jordahl said Monday that the litigation will continue even as the exchange goes forward.

“This court order is not the final word. These lands hold incredible spiritual, historical and conservation value for the people and wildlife of South Texas. We won’t stop fighting to keep this irreplaceable public wildlife refuge safe from SpaceX bulldozers,” Jordahl said in a statement.

The lawsuit asks the federal court to halt the exchange, which has worried SpaceX opponents in the area who have long criticized the company's expanding footprint over lost access to beaches and concerns over exploding rockets.

The Fish and Wildlife Service didn’t respond to a request for comment on Monday’s decision. Previously, a spokesperson had said the agency does not comment on ongoing litigation.

The agency issued a final environmental assessment report in June that determined the exchange would cause no significant impact to the area. The report said the federal government believed the acquisition would represent a “net conservation benefit” and provide “substantial long-term conservation value and improving landscape-scale habitat connectivity across refuges in South Texas.”

The judge said that the plaintiffs offered “relatively weak” evidence of environmental harm.

“While they rightfully argue that the preservation of wildlife and historical lands furthers the public interest, they present no evidence demonstrating that the Property will suffer aesthetic, environmental, cultural, or historical degradation during the pendency of this lawsuit,” Rodriguez wrote in his ruling.

In addition, the judge said a preliminary injunction would result in modifications to SpaceX’s development plans, “placing additional hardship on the company’s ability to meet milestones and contractual obligations.”

SpaceX did not return an email seeking comment on the judge's ruling.

The space exploration company first broke ground in Texas more than a decade ago and has expanded rapidly, so much that SpaceX employees last year voted to incorporate their own local government called Starbase.

Rice Alliance, Greentown name winners of Houston Energy and Climate Week pitch competitions

winner winners

Approximately 100 startups from around the world pitched their breakthrough technologies and businesses during Houston Energy and Climate Week, with a select few taking home top prizes and bragging rights.

Each year, investors at the Rice Alliance Energy Technology Venture Forum name the 10 most-promising startups. Greentown's Climatetech Summit also culminates in a pitch event, where member companies can earn cash prizes.

Here's who won at two of the week's anchor events and competitions.

Rice Alliance Energy Tech Venture Forum

The 23nd annual event was held Thursday, Sept. 17, at Rice University’s Jones Graduate School of Business. The most-promising companies were selected by industry experts and participating investors attending the event.

The 10 most-promising companies included:

  • Australia-based Aquafortus, which has developed a non-thermal liquid to liquid desalination technology for resource recovery from wastewater brine
  • Houston-based Focis AI, which converts industrial laser scans into a queryable digital twin of refineries and plants
  • Houston-based ironlattice, a semiconductor manufacturing company
  • Houston-based Licube, which has developed technology to produce ultra-high-purity lithium compounds for the fusion energy, pharmaceuticals, semiconductors and high-performance solid-state battery sectors
  • Houston-based Mars Materials, a clean chemical manufacturing business that is working to convert captured carbon into resources, such as carbon fiber and wastewater treatment chemicals
  • Dallas-based MCatalysis, which has developed a suite of proprietary microwave-driven catalysts to produce high-quality, ready-to-use fuels compatible with existing infrastructure
  • Oslo, Norway-based OTee, an automation machinery manufacturer
  • Houston-based Pike Robotics, which deploys its Wall-Eye robot to inspect hazardous tanks without taking assets offline
  • New Mexico-based Spiritus, a direct-air-capture (DAC) technology company
  • San Francisco-based UptimeAI Inc., which develops AI reasoning agents for industrial operations teams

Stellai won the People's Choice Award. The Norwegian company develops AI products for the waste management industry.

The energy technology ventures selected to participate in the forum were named earlier this year. See the full list here, and read about last year's winners here.

Greentown Lab's Climatetech Summit

The annual summit was held Wednesday, Sept. 16, featured a number of Houston startups in its pitch competition and lighting pitch round. Judges included Dave Dreessen,, Jon Greene, Naval Preet Singh, Philip Llewellyn, Erin Madro, Justin Yeung, Jay Kim, Rawand Rasheed and Moji Karimi.

Pitch winners included:

  • First place: Elementium Materials' CEO Matthew Dawson, winning a $10,000 cash prize sponsored by TotalEnergies plus another $10,000 in legal services sponsored by Foley Hoag. The company develops advanced battery electrolytes. It is a Greentown Boston member; though Dawson is based in Houston.
  • Second place: Houston-based Solidec CEO and co-founder Ryan DuChanois, winning $5,000 in legal services sponsored by Foley Hoag. The company electrolyzes air, water and electricity into onsite hydrogen peroxide.

Lightening pitch winners included:

  • First place: Montana-based MagDrive Technologies, winning a $1,000 cash prize sponsored by Energy Transition Ventures. The company develops magnetically actuated, zero-emission valve systems that eliminate fugitive emissions and improve reliability.
  • Second place: Houston-based HEXASpec, winning a $500 cash prize sponsored by Foley Hoag. The company has created a new material to improve heat management for the semiconductor industry.

Read Greentown's recap of the summit here.

Houston Energy and Climate Week announced that the 2027 event will move to the spring, held April 4-10.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.