CenterPoint and partners launch AI initiative to stabilize the power grid

AI infrastructure

CenterPoint, NVIDIA and Palantir have formed Chain Reaction. Photo via Getty Images

Houston-based utility company CenterPoint Energy is one of the founding partners of a new AI infrastructure initiative called Chain Reaction.

Software companies NVIDIA and Palantir have joined CenterPoint in forming Chain Reaction, which is aimed at speeding up AI buildouts for energy producers and distributors, data centers and infrastructure builders. Among the initiative’s goals are to stabilize and expand the power grid to meet growing demand from data centers, and to design and develop large data centers that can support AI activity.

“The energy infrastructure buildout is the industrial challenge of our generation,” Tristan Gruska, Palantir’s head of energy and infrastructure, says in a news release. “But the software that the sector relies on was not built for this moment. We have spent years quietly deploying systems that keep power plants running and grids reliable. Chain Reaction is the result of building from the ground up for the demands of AI.”

CenterPoint serves about 7 million customers in Texas, Indiana, Minnesota and Ohio. After Hurricane Beryl struck Houston in July 2024, CenterPoint committed to building a resilient power grid for the region and chose Palantir as its “software backbone.”

“Never before have technology and energy been so intertwined in determining the future course of American innovation, commercial growth, and economic security,” Jason Wells, chairman, president and CEO of CenterPoint, added in the release.

In November, the utility company got the go-ahead from the Public Utility Commission of Texas for a $2.9 billion upgrade of its Houston-area power grid. CenterPoint serves 2.9 million customers in a 12-county territory anchored by Houston.

A month earlier, CenterPoint launched a $65 billion, 10-year capital improvement plan to support rising demand for power across all of its service territories.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

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Despite its high energy production, Texas has had more outages than any other state over the past five years due to the increasing frequency and severity of extreme weather events and rapidly growing demand. Photo via Getty Images

Untapped potential: The role of residential energy management in Texas

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Texas stands out among other states when it comes to energy production.

Even after mass rolling blackouts during Winter Storm Uri in 2021, the Lone Star State produced more electricity than any other state in 2022. However, it also exemplifies how challenging it can be to ensure grid reliability. The following summer, the state’s grid manager, the Electrical Reliability Council of Texas (ERCOT), experienced ten occasions of record-breaking demand.

Despite its high energy production, Texas has had more outages than any other state over the past five years due to the increasing frequency and severity of extreme weather events and rapidly growing demand, as the outages caused by Hurricane Beryl demonstrated.

A bigger storm is brewing

Electric demand is poised to increase exponentially over the next few years. Grid planners nationwide are doubling their five-year load forecast. Texas predicts it will need to provide nearly double the amount of power within six years. These projections anticipate increasing demand from buildings, transportation, manufacturing, data centers, AI and electrification, underscoring the daunting challenges utilities face in maintaining grid reliability and managing rising demand.

However, Texas can accelerate its journey to becoming a grid reliability success story by taking two impactful steps. First, it could do more to encourage the adoption of distributed energy resources (DERs) like residential solar and battery storage to better balance the prodigious amounts of remote grid-scale renewables that have been deployed over the past decade. More DERs mean more local energy resources that can support the grid, especially local distribution circuits that are prone to storm-related outages. Second, by combining DERs with modern demand-side management programs and technology, utilities can access and leverage these additional resources to help them manage peak demand in real time and avoid blackout scenarios.

Near-term strategies and long-term priorities

Increasing electrical capacity with utility-scale renewable energy and storage projects and making necessary electrical infrastructure updates are critical to meet projected demand. However, these projects are complex, resource-intensive and take years to complete. The need for robust demand-side management is more urgent than ever.

Texas needs rapidly deployable solutions now. That’s where demand-side management comes in. This strategy enables grid operators to keep the lights on by lowering peak demand rather than burning more fossil fuels to meet it or, worse, shutting everything off.

Demand response, a demand-side management program, is vital in balancing the grid by lowering electricity demand through load control devices to ensure grid stability. Programs typically involve residential energy consumers volunteering to let the grid operator reduce their energy consumption at a planned time or when the grid is under peak load, typically in exchange for a credit on their energy bill. ERCOT, for example, implements demand responseand rate structure programs to reduce strain on the grid and plans to increase these strategies in the future, especially during the months when extreme weather events are more likely and demand is highest.

The primary solution for meeting peak demand and preventing blackouts is for the utility to turn on expensive, highly polluting, gas-powered “peaker” plants. Unfortunately, there’s a push to add more of these plants to the grid in anticipation of increasing demand. Instead of desperately burning fossil fuels, we should get more out of our existing infrastructure through demand-side management.

Optimizing existing infrastructure

The effectiveness of demand response programs depends in part on energy customers' participation. Despite the financial incentive, customers may be reluctant to participate because they don’t want to relinquish control over their AC. Grid operators also need timely energy usage data from responsive load control technology to plan and react to demand fluctuations. Traditional load control switches don’t provide these benefits.

However, intelligent residential load management technology like smart panels can modernize demand response programs and maximize their effectiveness with real-time data and unprecedented responsiveness. They can encourage customer participation with a less intrusive approach – unlocking the ability for the customer to choose from multiple appliances to enroll. They can also provide notifications for upcoming demand response events, allowing the customer to plan for the event or even opt-out by appliance. In addition to their demand response benefits, smart panels empower homeowners to optimize their home energy and unlock extended runtime for home batteries during a blackout.

Utilities and government should also encourage the adoption of distributed energy resources like rooftop solar and home batteries. These resources can be combined with residential load management technology to drastically increase the effectiveness of demand response programs, granting utilities more grid-stabilizing resources to prevent blackouts.

Solar and storage play a key role

During the ten demand records in the summer of 2023, batteries discharging in the evening helped avoid blackouts, while solar and wind generation covered more than a third of ERCOT's daytime load demand, preventing power price spikes.

Rooftop solar panels generate electricity that can be stored in battery backup systems, providing reliable energy during outages or peak demand. Smart panels extend the runtime of these batteries through automated energy optimization, ensuring critical loads are prioritized and managed efficiently.

Load management technology, like smart panels, enhances the effectiveness of DERs. In rolling blackouts, homeowners with battery storage can rely on smart panels to manage energy use, keeping essential appliances operational and extending stored energy usability. Smart panels allow utilities to effectively manage peak demand, enabling load flexibility and preventing grid overburdening. These technologies and an effective demand response strategy can help Texans optimize the existing energy capacity and infrastructure.

A more resilient energy future

Texas can turn its energy challenges into opportunities by embracing advanced energy management technologies and robust demand-side strategies. Smart panels and distributed energy resources like solar and battery storage offer a promising path to a resilient and efficient grid. As Texans navigate increasing electricity demands and extreme weather events, these innovations provide hope for a future where reliable energy is accessible to all, ensuring grid stability and enhancing the quality of life across the state.

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Kelly Warner is the CEO of Lumin, a responsive energy management solutions company.

This article originally ran on EnergyCapital.
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Rice launches 'brain economy' initiative at World Economic Forum

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Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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