Cruise is now cruising some Houston streets. The self-driving car service has launched with $5 flat-rate rides. Photo courtesy of Cruise

For the first time, Houstonians can hail an autonomous vehicle to get from point A to point B, thanks to a tech company's latest market roll out.

San Francisco-based Cruise, which has launched in its hometown, Phoenix, and Austin over the past year and a half, previously announced Houston and Dallas as the company's next stops. Dallas, where Cruise is currently undergoing testing, will roll out its service by the end of the year.

As of today, October 12, Houstonians in the Downtown, Midtown, East Downtown, Montrose, Hyde Park, and River Oaks neighborhoods can hail a ride from an autonomous electric vehicle seven days a week between the hours of 9 pm to 6 am.

"We believe that everyone has a right to safer, more accessible and more affordable transportation, and we remain focused on cities first because that’s where our mission will have the greatest impact. Houston follows that city-first strategy with its densely traversed downtown, propensity for ridehail, and vibrant cultural center," Sola Lawal, Cruise's Houston manager, tells InnovationMap. "Cruise also shares in Houston’s Vision Zero mission to end traffic deaths and serious injuries by 2030 and we’re excited to address the transportation needs of Houston communities."

Although today marks the launch to the public, Cruise's employees and their friends and family have been testing out the service since August.

"People love this shift from working for your car as the driver, to the car working for you and the time this gives people back in their days," he explains. "A common reaction from first time riders starts with people being shocked and awed for the first two minutes then the ride becomes so normal that you forget you're in a driverless car."

Founded in 2013 by CEO, CTO, and President Kyle Vogt and Chief Product Officer Dan Kan, Cruise vehicles have self-driven over 5 million miles — 1 million of those miles were cruised on Texas streets. The company's fleet includes 400 electric vehicles powered by renewable energy.

Cruise's plan for Houston is to launch and grow from there, including launching larger passenger vehicles, the Origin fleet, for bigger groups of people.

"We always start small and methodically expand from there. For us it’s all about safety and how we expand in partnership with communities, so we let that be our guide for expansion vs arbitrary timelines," Lawal says. "Our goal is to continue to expand as quickly and safely as possible so we can get folks to the Rodeo when it starts and back home, anywhere in Houston, when it ends. You can expect expanded map areas, increased supply of AVs, and expanded hours until we are 24/7 across Houston."

Cruise has raised $10 billion in capital commitments from investors, including General Motors, Honda, Microsoft, T. Rowe Price, Walmart, and others. Additionally, the tech company has also a $5 billion credit line with GM Financial, giving it the financial support needed to scale. Strategically aligned with General Motors and Honda, Cruise has fully integrated manufacturing at scale.

Cruise, which touts a pricing model competitive to existing rideshares, is launching with $5 flat-rate rides for passengers.

"Houstonians who ride with us have the chance to be part of history in the making," Lawal tells Houston's to-be Cruise riders. "The industry has made incredible progress in the last two years but we are still in the early days of what’s to come as driverless ridehail becomes a reality for more people.

"We are proud of the service we’ve built so far and the safety record we have to show for it, but will always continue to improve. We're excited to launch with the community of Houston and we simply ask that you give it a try," he continues. "And when you do please give us feedback, we’d love to hear about your experience."

Origin, a larger, six-person self-driving vehicle, will also launch in the Houston market once Cruise rolls it out. Rendering courtesy of Cruise

At an event last week, Evolve Houston celebrated its relaunch, a new leader, and its microgrant program. Photo courtesy of Evolve

Houston nonprofit relaunches, names new leader, and introduces electromobility initiative

evolve evolves

A Houston organization focused on promoting electromobility in Houston has announced some big updates.

Evolve Houston, founded in 2019 through Houston's Climate Action Plan, has relaunched as of its event Thursday, August 18. The nonprofit has also named Casey Brown as the new president and executive director. Formerly at Halliburton and Coretrax, Brown's appointment went into effect this month.

"I am honored to have been appointed by the board to lead Evolve into the next phase of our electric vehicle journey," says Brown. "I look forward to working with our partners to get more electric cars, buses, and bikes on the road, and to publish Evolve's electrification roadmap 2.0 early next year."

Additionally, thanks to funding from Evolve Corporate Catalysts General Motors and bp, the organization has introduced the eMobility Microgrant Initiative, which will facilitate a peer-review process to award microgrants to local electromobility projects. Applications for the grants are now open online and will be accepted through September 16 at 6 pm.

"Evolve Houston is committed to supporting a just transition to a more sustainable transportation system, so all residents can receive the benefits of eMobility," says Grace Millsap, Evolve Houston director of equity and investment, in a news release. "The Greater Houston area has made significant progress in improving livability. We must continue and bring the eMobility revolution to Houston's communities that remain disproportionately in need of a cleaner environment, better services, and diversified economic development.

"Evolve's eMobility Microgrant Initiative will empower and elevate residents' voices, drive further community investment, and prioritize the communities who are most impacted by climate and mobility challenges," she continues.

A community-focused initiative, the Equity Program has been established to address poor air quality and limited access to public transportation in vulnerable communities, per the release. This fall, Evolve will invest the microgrants into community-led efforts that are increasing access to all forms of electric mobility and EV charging stations.

"The Complete Communities Initiative bridges the gap between equity and opportunity for our city's most under-resourced and underserved neighborhoods. Residents living in the Complete Communities have made it clear that its past time to address the transportation and climate change challenges that impact their quality of life," says Shannon Buggs, director of the Mayor's Office for Complete Communities, in the release.

"Increasing chronic air pollution and lack of equitable mobility has disproportionately affected low-to-moderate income neighborhoods," she continues. "With the help of community leaders, the Evolve Houston Equity Program provides a pathway for our City to ensure that every resident lives in a healthy, sustainable and thriving community."

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Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”