This week's roundup of Houston innovators includes Adrianne Stone of Bayou City Startups, Sarma Velamuri of Luminare, and Curtis Jackson of G-Unity Foundation. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health tech to nonprofit — recently making headlines in Houston innovation.

Adrianne Stone, founder of Bayou City Startups

Every month, Adrianne Stone of Bayou City Startups hosts a happy hour for startup founders to create a safe space to network, collaborate, commensurate, and more. Photo courtesy of Adrianne Stone

Adrianne Stone knows firsthand how lonely the startup founder journey is, so she set out to help create a community for founders when she started Bayou City Startups last year. Now, Stone shares on the Houston Innovators Podcast that her monthly happy hours attract over 50 attendees on average.

"Being the venture associate with Capital Factory in Houston, I'd seen what the Houston ecosystem had to offer. There were events — happy hours, coffee meet-ups, all these things," Stone says on the show. "But it was not just a casual networking event usually. I wanted a consistent community where I could show up and say, 'guys, I had the worst week,' to people who got where I was coming from and who could commensurate or lean in and help."

The next opportunity to network with Bayou City Startups is Tuesday, July 18, from 5 to 7 pm at Kirby Ice House. Read more.

Sarma Velamuri, co-founder and CEO of Luminare

Sepsis has been the No. 1 killer hospitals, but this Houston startup has a tech to help mitigate the risk. Photo via Getty Images

When he was an internal medicine physician, Sarma Velamuri watched helplessly as a friend’s 22-year-old daughter lost her life to sepsis. He had to tell his friend that she would not be coming home.

“There are 300,000-plus people a year who die of sepsis,” says Velamuri. “It’s important that people understand it’s not just those who are most susceptible to infections.”

This fact is not only unfortunate, but preventable. And that’s why Velamuri, who describes himself as “a recovering hospitalist,” co-founded Luminare in 2014. A full-time CEO since 2017, Velamuri, who runs the company with co-founder and CTO Marcus Rydberg, is based in the TMC Innovation Factory. Read more.

Curtis Jackson, founder of the G-Unity Foundation

For the second year, Curtis Jackson's program supported Houston student entrepreneurs. Photo courtesy of G-Unity

Chances are, you've heard of 50 Cent — his 2003 album "Get Rich or Die Tryin'" was a soundtrack to many. But Curtis James Jackson III, 50 Cent's real name, has done a lot since gracing your radios. He moved to Houston in 2021 and founded the G-Unity Foundation. In May, he wrapped on the second year of the G-Unity Business Labs, a business development incubator for Houston Independent School District high schoolers.

"I’ve spent years donating my time and energy to communities in need. I started G-Unity to do the same—to give back to kids so they have it a little easier than I did," Jackson writes on the website. "Team building and entrepreneurship are skills I learned along the way, but they are so important to develop early. I look forward to G-Unity supporting programs that are doing the crucial work of teaching kids to excel at life."

Around 150 students participated, and the winners are splitting a $500,000 investment. Read more.

For the second year, Curtis Jackson's program supported Houston student entrepreneurs. Photo courtesy of G-Unity

50 Cent's Houston entrepreneurship program wraps with $500,000 investment into student-founded companies

student hustlers

The 50 Cent-backed high school entrepreneurship program wrapped up its second year of operation after helping over 100 Houston-area students build their small business plans.

G-Unity Business Labs, sponsored by Curtis James Jackson III — better known as 50 Cent — and Horizon International Group, allowed participants to build their own small businesses from the ground up. This year's cohort featured a variety of businesses, from a Caribbean hot dog food truck to a financial literacy course on personal finance.

In its second year, the program encouraged innovation and taught business acumen to entrepreneurial-minded high school students, culminating in an opportunity to create their dream companies. During this 28 week entrepreneurial internship program, around 150 students from Madison, Worthing, Yates, Kashmere, Booker T. Washington, and Wheatley high schools learned how to transform an idea they were passionate about into a full fledged product they can pitch to investors.

The after-school program consists of three stages – the first 20 weeks are about getting familiar with business concepts and building connections with peers and teacher volunteers. The next eight weeks are spent in the incubation phase as students are split up into teams and local entrepreneurs lead lessons, helping them workshop their ideas into a fleshed out corporation, before finally the teams compete in Hustle Tank, where students pitch their ideas to a panel of celebrity and entrepreneurial judges. At the event in May, the panel included 50 Cent and Mattress Mack. The five winning teams are now eligible to split $500,000 in seed money for their companies.

Summer Reeves, VP of design of Umbridge, is in charge of managing the incubation phase and said she has noticed a significant shift in the ideas the student groups have come up with between the two cohorts of the program; the first year saw flashier tech pitches. But during the second year of the program, Reeves said the students sought to address issues they see in their day-to-day lives, including a group who worked to develop support services to aid formerly incarcerated individuals after they are released.

“This year, a lot of students were more on the practical side,” Reeves tells InnovationMap. “We actually had three teams that were focused on mental health apps which I think is a great example of what youth today are really focused on.”

Reeves started off as a mentor to four teams during the incubation phase of the program last year providing students with guidance on how to set up their business plans, create prototypes, and pitch their companies to investors. After three of her teams won the Hustle Tank competition previously, she took over planning the incubation phase and recruiting other local entrepreneurs to act as mentors.

“We give them recommendations on how to pitch and how to frame their pitch but they also have the ability to get creative so we had some students who did short skits — some that did raps and spoken word type things — lots of creativity,” Reeves says.

Patrice Allen, senior manager of G-Unity Business Labs, said they use the students’ individual strengths and creative thought processes to place them into their teams, including asking them in interviews at the beginning of the year to try to sell her a pen to understand their pitching process.

“That’s the question the students always remember,” Allen says. “‘Sell us this pen or pick something out and sell it to us.’ It’s the weirdest thing and they love it.”

In building the teams at each school, Allen worked with educators to make sure every team had students with a variety of communication and planning skills as well as financial awareness. But Allen felt students were most successful when they incorporated their personal interests into their product design. The first place team of Hustle Tank, Caribbean Hot Dog Boyz, was especially emblematic of this mindset as they combined one member's background of selling hotdogs with another’s Caribbean heritage to create a food truck that sells the unexpected combo of oxtail hotdogs.

The first place team of Hustle Tank 2023 was Caribbean Hot Dog Boyz. Photo via @gunitybusinesslab/Instagram

“To actually taste the food that they prepared was phenomenal,” Allen says “I have never ever thought that oxtails on a hotdog would be good but everybody was floored.”

Elizabeth Martin, director of communications and marketing for Horizon who runs the behind the scenes of funding, said students from the winning teams are now working on solidifying their business plans to qualify for the funds from the G-Unity foundation to develop their companies. Martin also said 50 Cent will retain a relationship with these teams, acting with varying levels of involvement depending on his deal with the students as anything from a silent partner to an investor.

“They do not walk home with $500,000 in their back pocket,” Martin explains. “We are investing in (them) — not giving — it’s an investment.”

The future of this program is uncertain as the Texas Education Association’s takeover of HISD is still in its transition phase but Martin advised to keep a lookout for an ABC Nightline interview of 50 Cent discussing G-Unity Business Labs, which is expected to release soon.

"I’ve spent years donating my time and energy to communities in need. I started G-Unity to do the same—to give back to kids so they have it a little easier than I did," Jackson writes on the website. "Team building and entrepreneurship are skills I learned along the way, but they are so important to develop early. I look forward to G-Unity supporting programs that are doing the crucial work of teaching kids to excel at life.

Rob Schapiro of Microsoft joins the Houston Innovators Podcast to discuss DEI initiatives, translating between the tech in the energy sectors, AI, and more. Photo courtesy of Microsoft

Meet the innovator who's leveraging big tech to advance Houston's ecosystem equitably

HOUSTON INNOVATORS PODCAST EPISODE 188

At a glance, Rob Schapiro's resume might not make the most sense. A trained geologist with decades of experience in the energy sector, Schapiro made the move to Microsoft three years ago.

"I saw this disconnect between technology companies and energy companies — they didn't really speak the same language," he says on this week's episode of the Houston Innovators Podcast. "I thought I could help potentially solve this problem and work between the two as a sort of translator."

Now, as Microsoft’s Energy Acceleration Program director and site leader for the company’s Houston office, which is located in the Ion, Schapiro is deeply embedded in Houston's innovation ecosystem and is dedicated to helping advance Houston's role energy transition in a sustainable and equitable way.

Inspired by the murder of George Floyd, Schapiro says he sought out opportunities in his personal life to expand his contribution to the community as an ally, and he became a big brother in Big Brothers Big Sisters. Microsoft, too, is active in supporting the community through partnering with local organizations, including SUPERGirls SHINE Foundation, the G-Unity Foundation Inc., and more.

"This has been one of the most rewarding aspects of my job, that I've had the ability to leverage the might of Microsoft and my own privilege to have an impact on real people," Schapiro says. "Microsoft's mission is to empower every person and every organization on the planet to achieve more, and when you think about how you do that, it's really daunting. We realized that in order to do that, it's going to require a workforce that looks really different than it does today."

Microsoft knows too well the changing workforce, both from a diversity perspective and when it comes to artificial intelligence and other new technology. In its recent Work Trend Index report, the company found that, rather than being afraid of AI replacing jobs, the majority of the workforce is interested in applying AI to mundane tasks.

Schapiro shares more about his view of how AI will affect the workforce, plus what all the energy industry needs to focus on amid the energy transition, on the podcast. He also weighs in on how Houston's innovation ecosystem has evolved and where he hopes it's going. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

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Houston lands $14M in latest CPRIT grants to advance cancer, lab-on-chip research

cancer funding

Thanks to a $4 million grant from the Cancer Prevention and Research Institute of Texas, the University of Houston has recruited a top-tier researcher developing AI-powered lab-on-a-chip technology for early cancer detection.

Tianhong Cui, a professor of mechanical engineering at the University of Minnesota Twin Cities and an adjunct professor of physiology and biomedical engineering at the Mayo Clinic, specializes in microelectromechanical systems and advanced manufacturing at microscale and nanoscale levels. In addition to lab-on-a-chip systems, Cui focuses on biosensors and water sensors.

Lab-on-a-chip devices deliver big results in a tiny package

The CPRIT grant supports Cui’s development of a microscale lab-on-a-chip system for early cancer detection and post-therapy monitoring.

“Lab-on-a-chip technology crams an entire lab’s worth of functions into a tiny device roughly the size of a USB stick,” according to Built In.

Common uses for the technology include medical diagnostics, point-of-care testing, and environmental monitoring.

Lab-on-a-chip work being carried out at UH and elsewhere in Houston promises to revolutionize cancer detection and treatment. For instance, Houston biotech company iBiochips, a spinout from the Houston Methodist Research Institute, makes lab-on-a-chip devices that bolster cancer detection and therapy.

Four local organizations gain $10 million in CPRIT grants

Four other Houston-area organizations received an additional $10 million in grants in CPRIT’s latest round of funding:

  • University of Texas MD Anderson Cancer Center received two $2 million grants to recruit researchers Zheqi Li of Harvard University’s Dana-Farber Cancer Institute and Nikolaos Koundouros of Weill Cornell Medicine.
  • Rice University received one $2 million grant to recruit researcher Maria Akoppyan, formerly of the University of Southern California.
  • UT Medical Branch at Galveston received one $2 million grant to recruit researcher Cristina Santarossa of Johns Hopkins University.
  • Houston-based biopharma company Pulmotect received one $2 million grant to support better outcomes for cancer patients by activating immunity in the lungs as a first line of defense against germs.

The funding was part of $35 million in new CPRIT grants for institutions and companies across Texas approved at the organization's most recent meeting. To date, CPRIT has awarded more than $4.2 billion in grants.

“These awards support research across the cancer continuum from prevention to new classes of therapeutics,” said Dr. Scott Hiebert, chief scientific officer of CPRIT, said in a news release. “The work of these investigators will impact the lives of Texans across the state.”

2 Houston high schools soar as America's best for 2026, says U.S. News

Honor Roll

Houston ISD's Carnegie Vanguard High School is standing tall as one of the 25 best high schools in America, according to U.S. News and World Report's 2026-2027 Best High Schools rankings.

DeBakey High School for Health Professions also ranks among the top 100 nationally, and 23 more Houston-area schools join them at the top of the class in Texas.

Each year, U.S. News evaluates approximately 27,000 public high schools on six factors: college readiness, college curriculum breadth, state assessment proficiency, state assessment performance, underserved student performance, and graduation rates.

The highest ranking public schools provide the best educational environments where "students demonstrated outstanding outcomes above expectations in math, reading and science state assessments, earned qualifying scores on an array of college-level exams, and graduated in high proportions."

"Every student deserves a pathway to success, and that journey often begins with selecting the right school," said LaMont Jones, Ed.D., managing editor for education at U.S. News. "The 2026-2027 Best High Schools rankings empower families with the valuable data and transparency they need to help make the best educational choices for them. We are proud to offer this essential resource to help shape the next generation of college-ready students."

Top ranking Houston schools
Carnegie Vanguard High School once again leads in Texas as the No. 2 best high school, and soared as No. 25 in U.S. News' national list of the best high schools, up from No. 42 last year.

DeBakey High School for Health Professions is the 9th best high school in Texas and ranks No. 91 nationally (down from No. 75 last year).

Three more local schools ranked among the best STEM schools in the country: Memorial High School in Spring Branch ISD (No. 86), Seven Lakes High School in Katy ISD (No. 96), and Dulles High School in Fort Bend ISD (No. 99).

In U.S. News' ranking of the best charter schools, four Houston-area schools made the top 100: Spring Branch ISD's Westchester Academy for International Studies (No. 62), Harmony School of Innovation - Katy (No. 72), Harmony School of Discovery - Houston (No. 78), and YES Prep - North Central (No. 100).

Other Houston-area schools that rank among the 100 best in Texas are:

  • No. 17 – Kerr High School, Alief ISD, Houston
  • No. 24 – Young Women's College Prep Academy, Houston ISD
  • No. 25 – Kinder High School for Performing and Visual Arts, Houston ISD
  • No. 31 – Challenge Early College High School, Houston ISD
  • No. 39 – Westchester Academy for International Studies, Spring Branch ISD, Houston
  • No. 44 – Tomball Star Academy, Tomball ISD
  • No. 45 – Harmony School of Innovation - Katy
  • No. 46 – North Houston Early College High School, Houston ISD
  • No. 51 – Eastwood Academy, Houston ISD
  • No. 52 – Seven Lakes High School, Katy ISD
  • No. 54 – Harmony School of Discovery - Houston
  • No. 55 – Energy Institute High School, Houston ISD
  • No. 56 – Spring Early College Academy, Spring ISD
  • No. 63 – Sharpstown International School, Houston ISD
  • No. 66 – YES Prep - North Central, Houston
  • No. 73 – Tompkins High School, Katy ISD
  • No. 76 – YES Prep - Southeast, Houston
  • No. 80 – Harmony School of Innovation - Sugar Land
  • No. 81 – Clements High School, Fort Bend ISD, Sugar Land
  • No. 82 – Houston Academy for International Studies, Houston ISD
  • No. 86 – Jordan High School, Katy ISD
  • No. 88 – Victory Early College High School, Aldine ISD, Houston
  • No. 96 – Clear Horizons Early College High School, Clear Creek ISD, Houston

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This article originally appeared on CultureMap.com.

Intuitive Machines lands $600M satellite deal, NASA ‘spacecraft bus’ contract

space deals

Houston-based space infrastructure company Intuitive Machines has scored two astronomical deals.

The deals add to the company’s soaring success. As of June 30, Intuitive Machines had a record-high $1.8 billion backlog of orders, a $1.5 billion increase from the end of last year. The current backlog includes orders for more than 80 spacecraft.

The company, which went public in 2023, expects this year’s revenue to total $900 million to $1 billion. In the first half of 2026, Intuitive Machines generated nearly $393 million in revenue.

Intuitive Machines estimates its total available market is valued at more than $150 billion.

$600 million-plus deal represents ‘important milestone’

On Monday, Intuitive Machines said it picked up a $600 million-plus deal to develop three commercial satellites for an undisclosed customer over the course of about two years.

Intuitive Machines says it will design, manufacture, set up and support several spacecraft “for a critical communications infrastructure mission.”

Steve Altemus, the company’s CEO, says the deal represents “an important milestone for Intuitive Machines and reflects the confidence our customers place in our ability to deliver high-performance spacecraft for a broad range of mission needs.”

Company nails down NASA deal for ‘spacecraft bus’

A day after announcing the $600 million-plus deal, Intuitive Machines said it secured a new contract with NASA.

Intuitive Machines says NASA’s Jet Propulsion Laboratory in Southern California will use the company’s IM 300 “spacecraft bus” for an EAGLE-VSWIR Earth observation mission. The mission is scheduled to launch in 2028.

Aside from supplying the IM 300 bus, Intuitive Machines will carry out mission support services.

The low-Earth-orbit mission will be equipped with Intuitive Machines’ hyperspectral visible to shortwave infrared (VSWIR) instrument. This technology sees colors and details that aren’t visible to the human eye.

The instrument is “designed to perform surface biology and geology observations from Earth orbit while demonstrating technologies that could support future lunar and Mars exploration missions,” Intuitive Machines says.

Intuitive Machines builds mission-critical spacecraft, systems, and infrastructure for business and government customers. To date, the company has produced more than 300 spacecraft, delivered over 575 pounds of payload to the moon and launched about 100 satellites.